Network communities within and across borders.

abstract：:Previous reports suggest that offspring of mothers who smoke during pregnancy have greater risk of developing depression. However, it is unclear whether this is due to intrauterine effects. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC) from the UK (N = 2,869), the Nord-Trøndelag health s...

journal_title：Scientific reports

authors： Taylor AE,Carslake D,de Mola CL,Rydell M,Nilsen TIL,Bjørngaard JH,Horta BL,Pearson R,Rai D,Galanti MR,Barros FC,Romundstad PR,Davey Smith G,Munafò MR

更新日期：2017-10-03 00:00:00

abstract：:We demonstrated an abnormal double-peak (annular shaped) energy deposition through dual-wavelength synthesis of the fundamental frequency (ω) and the second-harmonic frequency (2ω) of a femtosecond (fs) Ti:sapphire laser. The annular shaped distribution of the dual-wavelength fs laser was confirmed through real beam s...

journal_title：Scientific reports

authors： Han W,Jiang L,Li X,Wang Q,Wang S,Hu J,Lu Y

更新日期：2017-12-11 00:00:00

abstract：:Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-κB-mediated inflammatory response. We investigated later phases of TNF signaling, after the initial transient induction of inflammatory genes has subsided, in primary human macrophages. TNF signaling induced expression of late response gen...

journal_title：Scientific reports

authors： Huynh L,Kusnadi A,Park SH,Murata K,Park-Min KH,Ivashkiv LB

更新日期：2016-08-25 00:00:00

abstract：:Multidimensional correlation magnetic resonance imaging (MRI) is an emerging imaging modality that is capable of disentangling highly heterogeneous and opaque systems according to chemical and physical interactions of water within them. Using this approach, the conventional three dimensional MR scalar images are repla...

journal_title：Scientific reports

authors： Pas K,Komlosh ME,Perl DP,Basser PJ,Benjamini D

更新日期：2020-02-24 00:00:00

abstract：:Multiple sequence alignment (MSA) is an integral part of molecular biology. But handling massive number of large sequences is still a bottleneck for most of the state-of-the-art software tools. Knowledge driven algorithms utilizing features of input sequences, such as high similarity in case of DNA sequences, can help...

journal_title：Scientific reports

authors： Vineetha V,Biji CL,Nair AS

更新日期：2019-04-29 00:00:00

abstract：:Identification of patients with early stage non-small cell lung cancer (NSCLC) with high risk of recurrence could help identify patients who would receive additional benefit from adjuvant therapy. In this work, we present a computational histomorphometric image classifier using nuclear orientation, texture, shape, and...

journal_title：Scientific reports

authors： Wang X,Janowczyk A,Zhou Y,Thawani R,Fu P,Schalper K,Velcheti V,Madabhushi A

更新日期：2017-10-19 00:00:00

abstract：:Obstructive heart defects (OHDs) are a major health concern worldwide. The platelet-derived growth factor (PDGF) genes are known to have regulatory functions that are essential for proper heart development. In a zebrafish model, Pdgfra was further demonstrated to interact with ethanol during craniofacial development. ...

journal_title：Scientific reports

authors： Tang X,Eberhart JK,Cleves MA,Li J,Li M,MacLeod S,Nembhard WN,Hobbs CA

更新日期：2018-07-23 00:00:00

abstract：:The gut microbiota (GM) is related to obesity and other metabolic diseases. To detect GM markers for obesity in patients with different metabolic abnormalities and investigate their relationships with clinical indicators, 1,914 Chinese adults were enrolled for 16S rRNA gene sequencing in this retrospective study. Base...

journal_title：Scientific reports

authors： Zeng Q,Li D,He Y,Li Y,Yang Z,Zhao X,Liu Y,Wang Y,Sun J,Feng X,Wang F,Chen J,Zheng Y,Yang Y,Sun X,Xu X,Wang D,Kenney T,Jiang Y,Gu H,Li Y,Zhou K,Li S,Dai W

更新日期：2019-09-17 00:00:00

abstract：:We introduce a new chemical space for drugs and drug-like molecules, exclusively based on their in silico ADME behaviour. This ADME-Space is based on self-organizing map (SOM) applied to 26,000 molecules. Twenty accurate QSPR models, describing important ADME properties, were developed and, successively, used as new m...

journal_title：Scientific reports

authors： Bocci G,Carosati E,Vayer P,Arrault A,Lozano S,Cruciani G

更新日期：2017-07-25 00:00:00

abstract：:We report the temperature dependence of the dielectric function ε = ε1 + iε2 and critical point (CP) energies of biaxial α-SnS in the spectral energy region from 0.74 to 6.42 eV and temperatures from 27 to 350 K using spectroscopic ellipsometry. Bulk SnS was grown by temperature gradient method. Dielectric response fu...

journal_title：Scientific reports

authors： Nguyen HT,Le VL,Nguyen TMH,Kim TJ,Nguyen XA,Kim B,Kim K,Lee W,Cho S,Kim YD

更新日期：2020-10-27 00:00:00

abstract：:Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae, a well-known Chinese medicinal herb that presents anticancer effects in various types of cancer cell lines. In this study, we have successfully established zebrafish xenografts with 5 various human cancer cell lines; and validated these models with ant...

journal_title：Scientific reports

authors： Zhu XY,Guo DW,Lao QC,Xu YQ,Meng ZK,Xia B,Yang H,Li CQ,Li P

更新日期：2019-03-14 00:00:00

abstract：:To unravel the molecular mechanism of defense against blister blight (BB) disease caused by an obligate biotrophic fungus, Exobasidium vexans, transcriptome of BB interaction with resistance and susceptible tea genotypes was analysed through RNA-seq using Illumina GAIIx at four different stages during ~20-day disease ...

journal_title：Scientific reports

authors： Jayaswall K,Mahajan P,Singh G,Parmar R,Seth R,Raina A,Swarnkar MK,Singh AK,Shankar R,Sharma RK

更新日期：2016-07-28 00:00:00

abstract：:We performed continuous recordings (May 2015 - January 2017) of hydraulic pressure and electrical conductivity of groundwater in the 190 m-long horizontal S13 borehole drilled next to the deep underground laboratories of Gran Sasso (LNGS-INFN), located in the core of the Gran Sasso carbonate aquifer (central Italy) at...

journal_title：Scientific reports

authors： De Luca G,Di Carlo G,Tallini M

更新日期：2018-10-29 00:00:00

abstract：:Electroporation (EP), the increase of cell membrane permeability due to the application of electric pulses, is a universal phenomenon with a broad range of applications. In medicine, some of the foremost EP-based tumor treatments are electrochemotherapy (ECT), irreversible electroporation, and gene electrotransfer (GE...

journal_title：Scientific reports

authors： Marino M,Luján E,Mocskos E,Marshall G

更新日期：2021-01-14 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Oviedo-Casado S,Urbina A,Prior J

更新日期：2018-03-13 00:00:00

abstract：:Bacterial outer membrane lipopolysaccharide (LPS) potently stimulates the mammalian innate immune system, and can lead to sepsis, the primary cause of death from infections. LPS is sensed by Toll-like receptor 4 (TLR4) in complex with its lipid-binding coreceptor MD-2, but subtle structural variations in LPS can profo...

journal_title：Scientific reports

authors： Paramo T,Tomasio SM,Irvine KL,Bryant CE,Bond PJ

更新日期：2015-12-09 00:00:00

abstract：:This study aimed to investigate changes in types of dental arch form during adolescence and explore adolescent changes in size and form of dental arch. Hong Kong Chinese were recruited and digital dental arch models were obtained at ages 12, 15, and 18 years. Geometric morphometrics was used to investigate adolescent ...

journal_title：Scientific reports

authors： Wen YF,Wong HM,Pei T,McGrath C

更新日期：2019-12-06 00:00:00

abstract：:Climate can modulate human health at large spatial scales, but the influence of global, regional, and local environments remains poorly understood, especially for neglected diseases, such as mycoses. In this work, we present the correlation between climatic variables and hospitalizations for mycoses in Brazilian state...

journal_title：Scientific reports

authors： Silva FB,Santos JRN,da Silva LC,Gomes WC,Villis PCM,Gomes EDS,Pinheiro EAD,Azevedo CMPES,Dias RDS,Monteiro CA,Santos JRA

更新日期：2019-05-06 00:00:00

abstract：:The graphdiyne (GD), a carbon allotrope with a 2D structure comprising benzene rings and carbon-carbon triple bonds, can be synthesized through cross-coupling on the surface of copper foil. The key problem is in understanding the dependence of layers number and properties, however, the controlled growth of the layers ...

journal_title：Scientific reports

authors： Qian X,Liu H,Huang C,Chen S,Zhang L,Li Y,Wang J,Li Y

更新日期：2015-01-13 00:00:00

abstract：:The use of cardiac troponins (cTn) is the gold standard for diagnosing myocardial infarction. Independent of myocardial infarction (MI), however, sex, age and kidney function affect cTn levels. Here we developed a method to adjust cTnI levels for age, sex, and renal function, maintaining a unified cut-off value such a...

journal_title：Scientific reports

authors： Boeckel JN,Palapies L,Klotsche J,Zeller T,von Jeinsen B,Perret MF,Kleinhaus SL,Pieper L,Tzikas S,Leistner D,Bickel C,Stalla GK,Lehnert H,Lindahl B,Wittchen HU,Silber S,Baldus S,Maerz W,Dimmeler S,Blankenberg S,Mün

更新日期：2018-05-24 00:00:00

abstract：:The restoration of dentine lost in deep caries lesions in teeth is a routine and common treatment that involves the use of inorganic cements based on calcium or silicon-based mineral aggregates. Such cements remain in the tooth and fail to degrade and thus normal mineral volume is never completely restored. Here we de...

journal_title：Scientific reports

authors： Neves VC,Babb R,Chandrasekaran D,Sharpe PT

更新日期：2017-01-09 00:00:00

abstract：:We have recently demonstrated that the rate-limiting enzymes in human glucose metabolism organize into cytoplasmic clusters to form a multienzyme complex, the glucosome, in at least three different sizes. Quantitative high-content imaging data support a hypothesis that the glucosome clusters regulate the direction of ...

journal_title：Scientific reports

authors： Jeon M,Kang HW,An S

更新日期：2018-02-09 00:00:00

abstract：:Prostate cancer is the most commonly diagnosed cancer in men with African American men disproportionally suffering from the burden of this disease. Biomarkers that could discriminate indolent from aggressive and drug resistance disease are lacking. MicroRNAs are small non-coding RNAs that affect numerous physiological...

journal_title：Scientific reports

authors： Cagle P,Niture S,Srivastava A,Ramalinga M,Aqeel R,Rios-Colon L,Chimeh U,Suy S,Collins SP,Dahiya R,Kumar D

更新日期：2019-07-05 00:00:00

abstract：:In the field of correlative microscopy, light and electron microscopy form a powerful combination for morphological analyses in zoology. Due to sample thickness limitations, these imaging techniques often require sectioning to investigate small animals and thereby suffer from various artefacts. A recently introduced n...

journal_title：Scientific reports

authors： Ferstl S,Schwaha T,Ruthensteiner B,Hehn L,Allner S,Müller M,Dierolf M,Achterhold K,Pfeiffer F

更新日期：2020-03-03 00:00:00

abstract：:Organic thin-film transistors for high frequency applications require large transconductances in combination with minimal parasitic capacitances. Techniques aiming at eliminating parasitic capacitances are prone to produce a mismatch between electrodes, in particular gaps between the gate and the interlayer electrodes...

journal_title：Scientific reports

authors： Zojer K,Rothländer T,Kraxner J,Schmied R,Palfinger U,Plank H,Grogger W,Haase A,Gold H,Stadlober B

更新日期：2016-09-27 00:00:00

abstract：:We report on a combined photoluminescence imaging and atomic force microscopy study of single, isolated self-assembled InAs quantum dots. The motivation of this work is to determine an approach that allows to assess single quantum dots as candidates for quantum nanophotonic devices. By combining optical and scanning p...

journal_title：Scientific reports

authors： Sapienza L,Liu J,Song JD,Fält S,Wegscheider W,Badolato A,Srinivasan K

更新日期：2017-07-24 00:00:00

abstract：:The yield of pepper plants (Capsicum spp.) is their most important trait and is affected by the flower number and flowering time. Capsicum annuum produces a single flower per node and has an early flowering habit. By contrast, Capsicum chinense yields multiple flowers per node and has a late flowering character. Howev...

journal_title：Scientific reports

authors： Zhu Z,Sun B,Wei J,Cai W,Huang Z,Chen C,Cao B,Chen G,Lei J

更新日期：2019-01-31 00:00:00

abstract：:The development of a low-cost, fast, and large-scale process for the synthesis and manipulation of nanostructured metal oxides is essential for incorporating materials with diverse practical applications. Herein, we present a facile one-pot synthesis method using combustion waves that simultaneously achieves fast redu...

journal_title：Scientific reports

authors： Shin J,Lee KY,Yeo T,Choi W

更新日期：2016-02-23 00:00:00

abstract：:The activation of the majority of AGC kinases is regulated by two phosphorylation events on two conserved serine/threonine residues located on the activation loop and on the hydrophobic motif, respectively. In AGC kinase family, phosphomimetic substitutions with aspartate or glutamate, leading to constitutive activati...

journal_title：Scientific reports

authors： Somale D,Di Nardo G,di Blasio L,Puliafito A,Vara-Messler M,Chiaverina G,Palmiero M,Monica V,Gilardi G,Primo L,Gagliardi PA

更新日期：2020-01-17 00:00:00

abstract：:The ability to reprogram adult somatic cells into induced pluripotent stem cells (iPSCs) and the subsequent development of protocols for their differentiation into disease-relevant cell types have enabled in-depth molecular analyses of multiple disease states as hitherto impossible. Neurons differentiated from patient...

journal_title：Scientific reports

authors： Heman-Ackah SM,Bassett AR,Wood MJ

更新日期：2016-06-24 00:00:00