Abstract:
PURPOSE:Often PIRADS 3 findings are usually followed up with further MRIs of the prostate. Current guidelines do not state an optimal interval between the initial MRI and the follow-up MRI. The aim of this study was to find out if PIRADS 3 lesions evolve over time and to determine how long the optimal interval between initial MRI and follow-ups should be. METHODS:In this retrospective study, 141 consecutive patients were included who underwent at least one follow-up MRI after an initial PIRADS 3 finding. Changes in PIRADS score and the interval between the first and the follow-up MRI were recorded. An optimal duration was calculated. RESULTS:Of all patients, 76.6% had a change from PIRADS 3 to either 2 or 4 in the first follow-up MRI. Reclassifications to PIRADS 4 happened earlier than reclassifications to PIRADS 2 (after 366.5 ± 217.9 days and after 534.2 ± 253.0 days, respectively). An optimal point of time for a follow-up to distinguish between changes to PIRADS 2 versus PIRADS 4 turned out to be 379 days (12.4 months, AUC 0.734, p = 0.0001). Of all patients with a PIRADS 3 lesion 14.8% harboured a prostate carcinoma. CONCLUSION:Performing follow-up mpMRI rather than immediate biopsy may be beneficial for patients with PIRADS 3, as most lesions can be reclassified after a manageable period of time. Upgrades to PIRADS 4 seem to happen earlier and within fewer follow-ups than downgrades to PIRADS 2. The optimal interval for follow-up MRIs seems to be 12.4 months.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Steinkohl F,Gruber L,Bektic J,Nagele U,Aigner F,Herrmann TRW,Rieger M,Junker Ddoi
10.1007/s00345-017-2135-0subject
Has Abstractpub_date
2018-03-01 00:00:00pages
367-373issue
3eissn
0724-4983issn
1433-8726pii
10.1007/s00345-017-2135-0journal_volume
36pub_type
杂志文章abstract:BACKGROUND:Chronic intraprostatic inflammation is suspected to play a major role in the pathogenesis of prostate cancer (PCa). Polymorphisms in interleukin-10 (IL-10), a key anti-inflammatory cytokine gene can influence immune response and immune evasion of tumor cells. Its role as an anti-metastatic molecule is also w...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-008-0361-1
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:Monopolar transurethral resection of the prostate (TURP) is the gold standard surgical treatment for bothersome moderate to severe lower urinary tract symptoms (LUTS) secondary to benign prostate obstruction. The aim of the study is to compare monopolar versus bipolar TURP focusing on operative and functiona...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-017-2023-7
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:To place chemoprevention of prostate cancer in current clinical context. METHODS:Review of recently published updates of large, randomized, controlled trials of primary chemoprevention of prostate cancer. RESULTS:With extended post-intervention follow-up, SELECT demonstrated a 17% increased risk of prostat...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0822-9
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:Our objective was to determine the impact of preoperative frailty, as measured by validated Risk Analysis Index (RAI), on the occurrence of postoperative complications after urologic surgeries in a national database comprised of diverse practice groups and cases. STUDY DESIGN:The National Surgical Quality Impr...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-016-1845-z
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:We aimed to investigate the association between nocturia and serum metabolites identified using metabolomics analysis. METHODS:This study enrolled 66 men aged 65-80 years, recruited from the outpatient department of a university hospital. The participants were stratified as follows: Nocturia group [45 men with...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02647-4
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:Natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single-site surgery (LESS) are the next steps in the evolution of laparoscopic surgery, promising reduced morbidity and improved cosmetic result. The inconsistent terminology initially used led to confusion. Understanding the tech...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-012-0899-9
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To assess oncologic outcomes after salvage radiotherapy (SRT) without androgen deprivation therapy (ADT) in patients with persistently detectable PSA after radical prostatectomy (RT). METHODS:Two hundred and one patients who failed to achieve an undetectable PSA received SRT without ADT. The primary endpoint w...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-013-1214-0
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To compare prognostic performance of MSKCC and IMDC risk models in patients with synchronous mRCC. METHODS:Retrospective analysis of pre-therapeutic MSKCC and IMDC prognostic factors and outcomes in patients with synchronous mRCC treated at a single institute in the targeted therapy era was performed. Cytoredu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-016-1769-7
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2291-x
更新日期:2018-10-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1571-y
更新日期:2015-12-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1379-1
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:The significance of a positive UroVysion FISH assay is uncertain in patients with normal cystoscopy. This multicenter study evaluates the clinical significance of a positive FISH assay in patients with no visible tumor and excluding those with a positive cytology. METHODS:A multi-institutional, retrospectiv...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1452-9
更新日期:2015-09-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
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更新日期:2020-08-31 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章,评审
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更新日期:2019-01-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0932-z
更新日期:2013-04-01 00:00:00
abstract::One of the historic landmarks in urology is the first planned nephrectomy performed in 1869 by Gustav Simon of Heidelberg (1824-1877). In the history of medicine the reflections and considerations of the specialized surgeon reveal distinguished analyses of the "case" and, thus, the beginning of a modern scientific dis...
journal_title:World journal of urology
pub_type: 传,历史文章,杂志文章
doi:10.1007/s003450050125
更新日期:1999-06-01 00:00:00
abstract::Gastrin releasing peptide (GRP) is a neuropeptide that has been suggested to play a role in the development of some malignancies. Our aim was: (1) to identify the expression of GRP in cancerous prostate glands, and (2) to correlate its expression to various pathological parameters and to the patient's clinical outcome...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-003-0339-y
更新日期:2003-08-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1257-x
更新日期:2014-12-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0099-6
更新日期:2006-06-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-008-0238-3
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:Data assessing the effectiveness of single-use flexible ureteropyeloscopy (FURS) are limited. This study evaluates and compares single-use FURS with conventional reusable FURS. METHODS:A systematic search using electronic databases (Pubmed and Embase) was performed for studies evaluating single-use FURS in the...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-017-2131-4
更新日期:2018-04-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2187-9
更新日期:2018-05-01 00:00:00
abstract:PURPOSE/OBJECTIVE(S):Recent in vitro and in vivo evidence has suggested that statin medications may have anticancer activity. We sought to determine whether statin use was associated with improved clinical outcome in men treated with brachytherapy for prostate cancer. MATERIALS/METHODS:A database of men with prostate ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1281-x
更新日期:2015-01-01 00:00:00
abstract::The aim of this cross-sectional study was to compare single with repeated high-intensity focused ultrasound (HIFU) treatment in patients with localized prostate cancer, regarding treatment-related morbidity. A number of 223 consecutive patients with localized prostate cancer were treated with HIFU. Among them, 174 (78...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0107-x
更新日期:2006-11-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03151-w
更新日期:2020-03-14 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the factors affecting the lower urinary tract symptoms (LUTS) related quality of life (QoL) score. METHODS:This retrospective study analyzed 29,123 men who underwent health check-ups from January 2007 to July 2011 at a single institution. Those patients who completed th...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2052-2
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:The introduction of robotic surgical technology into urological reconstruction, particularly pediatrics, has introduced new horizons for reducing the morbidity and enhancing the efficacy of surgical repair of congenital conditions in children. In reviewing the evolution of pediatric urological applications of r...
journal_title:World journal of urology
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To systematically analyze the impact of prophylactic abdominal or retroperitoneal drain placement or omission in uro-oncologic surgery. METHODS:This systematic review follows the Cochrane recommendations and was conducted in line with the PRISMA and the AMSTAR-II criteria. A comprehensive database search inclu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02978-2
更新日期:2020-08-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00