Abstract：
:Spontaneous contractions and those elicited by electrical stimulation were studied in isolated segments of bovine mesenteric lymphatic vessels. The effects of three general anesthetics, pentobarbitone, halothane, and ether, on these spontaneous and evoked contractions were studied. Pentobarbitone and halothane inhibited spontaneous contractions in a dose-dependent fashion. In doses of 10(-4) M or greater both drugs completely abolished spontaneous contractility but when contractions were elicited by electrical stimulation pentobarbitone inhibited them in a dose-dependent manner whereas halothane did not. In contrast to the above results ether in doses as high as 10(-2) M had little effect on lymphatic contractility. It is concluded that, in doses similar to plasma levels found during general anaesthesia, halothane and pentobarbitone significantly depressed lymphatic contractility while ether did not.
journal_name
Microvasc Resjournal_title
Microvascular researchauthors
McHale NG,Thornbury KDdoi
10.1016/0026-2862(89)90073-3subject
Has Abstractpub_date
1989-01-01 00:00:00pages
70-6issue
1eissn
0026-2862issn
1095-9319journal_volume
37pub_type
杂志文章abstract：:We describe a sensitive, reliable, and convenient procedure to assay cell adhesion based on flow cytometry which allows quantitative studies of all major peripheral blood leukocytes adhering to microvascular endothelial cells. Using this assay, we show that adhesion of mononuclear cells is significantly increased in t...
journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1996.0047
更新日期：1996-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(83)90012-2
更新日期：1983-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2012.03.010
更新日期：2012-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1993.1048
更新日期：1993-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1997.2043
更新日期：1997-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(89)90046-0
更新日期：1989-05-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1997.2015
更新日期：1997-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2012.10.002
更新日期：2013-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
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更新日期：2002-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(91)90012-z
更新日期：1991-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1998.2105
更新日期：1998-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.2002.2437
更新日期：2002-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.2002.2421
更新日期：2002-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2018.11.002
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Sepsis is a fatal systemic inflammatory response syndrome caused by severe infection. The aim of this study was to measure hepatic microcirculation during the sepsis with laser speckle contrast imaging (LSCI), as well as investigating the underlying mechanisms. METHODS:Sepsis was induced by cecal ligation a...
journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2014.10.006
更新日期：2015-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1997.2045
更新日期：1998-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2004.11.001
更新日期：2005-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
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更新日期：2000-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2012.06.011
更新日期：2012-11-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.mvr.2014.05.008
更新日期：2014-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(84)90030-x
更新日期：1984-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(85)90051-2
更新日期：1985-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2004.08.003
更新日期：2004-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章,评审
doi：10.1016/j.mvr.2009.03.004
更新日期：2009-06-01 00:00:00
abstract：:A study was designed to compare three independent measures of cutaneous blood flow in normal healthy volunteers: xenon-133 washout, helium flux, and laser velocimetry. All measurements were confined to the volar aspect of the forearm. In a large group of subjects we found that helium flux through intact skin changes n...
journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(88)90058-1
更新日期：1988-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1999.2146
更新日期：1999-05-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2009.07.006
更新日期：2009-12-01 00:00:00
abstract：:Excessive generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), by activated neutrophils and endothelial cells, has been implicated in the pathophysiology of endothelial barrier dysfunction. Disruption of the integrity of this barrier markedly increases permeability to fluids, solutes and in...
journal_title：Microvascular research
pub_type： 杂志文章,评审
doi：10.1016/j.mvr.2008.10.005
更新日期：2009-01-01 00:00:00
