Abstract:
:This corrects the article DOI: 10.1038/nature19356.
journal_name
Naturejournal_title
Natureauthors
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie Helmut Fucdoi
10.1038/nature24643subject
Has Abstractpub_date
2017-11-16 00:00:00pages
398issue
7680eissn
0028-0836issn
1476-4687pii
nature24643journal_volume
551pub_type
杂志文章,已发布勘误相关文献
NATURE文献大全abstract::Temperature-sensitive paralysis is the most striking defect of adult Drosophila carrying the shibire mutation. This is believed to be due to a reversible block of endocytosis, which prevents membrane cycling and thus depletes synaptic vesicles. The shibire mutation also affects many tissues outside the nervous system....
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/351411a0
更新日期:1991-05-30 00:00:00
abstract::Transport of fermions, particles with half-integer spin, is central to many fields of physics. Electron transport runs modern technology, defining states of matter such as superconductors and insulators, and electron spin is being explored as a new carrier of information. Neutrino transport energizes supernova explosi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09989
更新日期:2011-04-14 00:00:00
abstract::In this Letter, Supplementary Fig. 1 was missing. This error has been corrected online. ...
journal_title:Nature
pub_type: 已发布勘误
doi:10.1038/s41586-019-1207-2
更新日期:2019-05-01 00:00:00
abstract::Thermoelectric materials are of interest for applications as heat pumps and power generators. The performance of thermoelectric devices is quantified by a figure of merit, ZT, where Z is a measure of a material's thermoelectric properties and T is the absolute temperature. A material with a figure of merit of around u...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35098012
更新日期:2001-10-11 00:00:00
abstract::Single-stranded RNA viruses encompass broad classes of infectious agents and cause the common cold, cancer, AIDS and other serious health threats. Viral replication is regulated at many levels, including the use of conserved genomic RNA structures. Most potential regulatory elements in viral RNA genomes are uncharacte...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature08237
更新日期:2009-08-06 00:00:00
abstract::The existence of so great a diversity of species on Earth remains a mystery, the solution to which may also explain why and how biodiversity influences the functioning of ecosystems. The answer may lie in quantifying the trade-offs that organisms face in dealing with the constraints of their environment. Societal resp...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35012217
更新日期:2000-05-11 00:00:00
abstract::Membrane-bound receptors often form large assemblies resulting from binding to soluble ligands, cell-surface molecules on other cells and extracellular matrix proteins. For example, the association of membrane proteins with proteins on different cells (trans-interactions) can drive the oligomerization of proteins on t...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature10183
更新日期:2011-07-27 00:00:00
abstract::Light absorption by the visual pigment rhodopsin triggers, through G-protein coupling, a cascade of events in the outer segment of the rod cell of the vertebrate retina that results in membrane hyperpolarization and nerve excitation. Rhodopsin, which contains 348 amino acids, has seven helices that cross the disk memb...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/362770a0
更新日期:1993-04-22 00:00:00
abstract::Circulating tumour cells in women with advanced oestrogen-receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer acquire a HER2-positive subpopulation after multiple courses of therapy. In contrast to HER2-amplified primary breast cancer, which is highly sensitive to HER2-targete...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature19328
更新日期:2016-09-01 00:00:00
abstract:: ...
journal_title:Nature
pub_type: 评论,信件
doi:10.1038/d41586-019-00232-8
更新日期:2019-01-01 00:00:00
abstract::Ordinarily, photons do not interact with one another. However, atoms can be used to mediate photonic interactions1,2, raising the prospect of forming synthetic materials3 and quantum information systems4-7 from photons. One promising approach combines highly excited Rydberg atoms8-12 with the enhanced light-matter cou...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1354-5
更新日期:2019-07-01 00:00:00
abstract::Individuals with congenital or acquired prolongation of the QT interval, or long QT syndrome (LQTS), are at risk of life-threatening ventricular arrhythmia. LQTS is commonly genetic in origin but can also be caused or exacerbated by environmental factors. A missense mutation in the L-type calcium channel Ca(V)1.2 lead...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09855
更新日期:2011-03-10 00:00:00
abstract::Cell competition-the sensing and elimination of less fit 'loser' cells by neighbouring 'winner' cells-was first described in Drosophila. Although cell competition has been proposed as a selection mechanism to optimize tissue and organ development, its evolutionary generality remains unclear. Here, by using live imagin...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1199-y
更新日期:2019-05-01 00:00:00
abstract::Fireflies communicate with each other by emitting yellow-green to yellow-orange brilliant light. The bioluminescence reaction, which uses luciferin, Mg-ATP and molecular oxygen to yield an electronically excited oxyluciferin species, is carried out by the enzyme luciferase. Visible light is emitted during relaxation o...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04542
更新日期:2006-03-16 00:00:00
abstract::Cytotoxic T cells lyse only those virus infected target cells in vitro which express, in addition to the viral antigen(s), those K or D region products of the major histocompatibility complex (MHC) which were present during anti-viral sensitisation in vivo. This 'associative recognition' by cytotoxic T cells could ref...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/267160a0
更新日期:1977-05-12 00:00:00
abstract::Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis, which is a significant cause of morbidity in China and the Philippines. Here we present a draft genomic sequence for the worm. The genome provides a global insight into the molecular architecture and host interaction of this complex metaz...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature08140
更新日期:2009-07-16 00:00:00
abstract::Cornelia de Lange syndrome (CdLS) is a dominantly inherited congenital malformation disorder, caused by mutations in the cohesin-loading protein NIPBL for nearly 60% of individuals with classical CdLS, and by mutations in the core cohesin components SMC1A (~5%) and SMC3 (<1%) for a smaller fraction of probands. In hum...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11316
更新日期:2012-09-13 00:00:00
abstract::Histone post-translational modifications (PTMs) are associated with epigenetic states that form the basis for cell-type-specific gene expression1,2. Once established, histone PTMs can be maintained by positive feedback involving enzymes that recognize a pre-existing histone modification and catalyse the same modificat...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-018-0239-3
更新日期:2018-06-01 00:00:00
abstract::How the brain selects appropriate sensory inputs and suppresses distractors is unknown. Given the well-established role of the prefrontal cortex (PFC) in executive function, its interactions with sensory cortical areas during attention have been hypothesized to control sensory selection. To test this idea and, more ge...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature15398
更新日期:2015-10-29 00:00:00
abstract::The cyanobacterium Prochlorococcus is the dominant oxygenic phototroph in the tropical and subtropical regions of the world's oceans. It can grow at a range of depths over which light intensities can vary by up to 4 orders of magnitude. This broad depth distribution has been hypothesized to stem from the coexistence o...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/30965
更新日期:1998-06-04 00:00:00
abstract::Targeting of proteins to appropriate subcellular compartments is a crucial process in all living cells. Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome. The SRP-riboso...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature08870
更新日期:2010-05-27 00:00:00
abstract::Sex roles are typically thought of as being fixed for a given species. In most animals males compete for females, whereas the females are more reluctant to mate. Therefore sexual selection usually acts most strongly on males. This is explained by males having a higher potential reproductive rate than females, leading ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature02562
更新日期:2004-06-03 00:00:00
abstract::Achieving site selectivity in carbon-hydrogen (C-H) functionalization reactions is a long-standing challenge in organic chemistry. The small differences in intrinsic reactivity of C-H bonds in any given organic molecule can lead to the activation of undesired C-H bonds by a non-selective catalyst. One solution to this...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature12963
更新日期:2014-03-13 00:00:00
abstract::When a force deforms an elastic object, practical experience suggests that the resulting displacement will be in the same direction as the force. This property is known as positive stiffness. Less familiar is the concept of negative stiffness, where the deforming force and the resulting displacement are in opposite di...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35069035
更新日期:2001-03-29 00:00:00
abstract::The Rab GTPases function as specific regulators of membrane transport. The GTP/GDP cycle is believed to control shuttling of Rab proteins between the cytosol and organelle membranes. In vitro, Rab proteins are removed from membranes by a protein that inhibits GDP dissociation (rabGDI), which leads to formation of a cy...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/368157a0
更新日期:1994-03-10 00:00:00
abstract::Population-level analyses often use average quantities to describe heterogeneous systems, particularly when variation does not arise from identifiable groups. A prominent example, central to our current understanding of epidemic spread, is the basic reproductive number, R(0), which is defined as the mean number of inf...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04153
更新日期:2005-11-17 00:00:00
abstract::The age of dense interstellar cloud cores, where stars and planets form, is a crucial parameter in star formation and difficult to measure. Some models predict rapid collapse, whereas others predict timescales of more than one million years (ref. 3). One possible approach to determining the age is through chemical cha...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13924
更新日期:2014-12-11 00:00:00
abstract::A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resu...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11209
更新日期:2012-06-13 00:00:00
abstract::Methane-oxidizing bacteria (methanotrophs) require large quantities of copper for the membrane-bound (particulate) methane monooxygenase. Certain methanotrophs are also able to switch to using the iron-containing soluble methane monooxygenase to catalyse methane oxidation, with this switchover regulated by copper. Met...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature14854
更新日期:2015-09-03 00:00:00
abstract::Magnetars are neutron stars with X-ray and soft γ-ray outbursts thought to be powered by intense internal magnetic fields. Like conventional neutron stars in the form of radio pulsars, magnetars exhibit 'glitches' during which angular momentum is believed to be transferred between the solid outer crust and the superfl...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature12159
更新日期:2013-05-30 00:00:00