Bisoprolol protects myocardium cells against ischemia/reperfusion injury by attenuating unfolded protein response in rats.

abstract：:A new extraordinary application of deoxyribonucleic acid (DNA) thin-solid-film was experimentally explored in the field of ultrafast nonlinear photonics. Optical transmission was investigated in both linear and nonlinear regimes for two types of DNA thin-solid-films made from DNA in aqueous solution and DNA-cetyltrime...

journal_title：Scientific reports

authors： Khazaeinezhad R,Hosseinzadeh Kassani S,Paulson B,Jeong H,Gwak J,Rotermund F,Yeom DI,Oh K

更新日期：2017-01-27 00:00:00

abstract：:Waddlia chondrophila is a Gram-negative intracellular bacterial organism that is related to classical chlamydial species and has been implicated as a cause of abortion in cattle. Despite an increasing number of observational studies linking W. chondrophila infection to cattle abortion, little direct experimental evide...

journal_title：Scientific reports

authors： Wheelhouse N,Flockhart A,Aitchison K,Livingstone M,Finlayson J,Flachon V,Sellal E,Dagleish MP,Longbottom D

更新日期：2016-11-14 00:00:00

abstract：:Drug delivery by micro- and nano-carriers enables controlled transport of pharmaceuticals to targeted sites. Even though carrier fabrication has made much progress recently, the delivery including controlled particle distribution and adhesion within the body remains a great challenge. The adhesion of carriers is stron...

journal_title：Scientific reports

authors： Müller K,Fedosov DA,Gompper G

更新日期：2014-05-02 00:00:00

abstract：:Gastric cancer is one of the most aggressive cancers and is the second leading cause of cancer death worldwide. Approximately 40% of global gastric cancer cases occur in China, with peritoneal metastasis being the prevalent form of recurrence and metastasis in advanced disease. Currently, there are limited clinical ap...

journal_title：Scientific reports

authors： Zhang J,Huang JY,Chen YN,Yuan F,Zhang H,Yan FH,Wang MJ,Wang G,Su M,Lu G,Huang Y,Dai H,Ji J,Zhang J,Zhang JN,Jiang YN,Chen SJ,Zhu ZG,Yu YY

更新日期：2015-09-02 00:00:00

abstract：:Given that drug abuse and dependence are common reasons for hospitalization, we aimed to derive and validate a model allowing early identification of life-threatening hospital admissions for drug dependence or abuse. Using the French National Hospital Discharge Data Base, we extracted 66,101 acute inpatient stays for ...

journal_title：Scientific reports

authors： Nguyen TL,Boudemaghe T,Leguelinel-Blache G,Eiden C,Kinowski JM,Le Manach Y,Peyrière H,Landais P

更新日期：2017-03-14 00:00:00

abstract：:Our goal was to evaluate early results of the clinical application of autologous whole bone marrow stem cell transplantation (AWBMSCT) for critical limb ischemia (CLI) in patients with Buerger's disease. We retrospectively analyzed the data of 58 limbs of 37 patients (mean age, 43.0 years; range, 28-63 years; male, 91...

journal_title：Scientific reports

authors： Heo SH,Park YS,Kang ES,Park KB,Do YS,Kang KS,Kim DI

更新日期：2016-01-21 00:00:00

abstract：:In this study, we report on a new approach for remote temperature probing that provides accuracy as good as 0.017°C (0.0055% accuracy) by measuring the magnetisation curve of magnetic nanoparticles. We included here the theoretical model construction and the inverse calculation method, and explored the impact caused b...

journal_title：Scientific reports

authors： Zhong J,Liu W,Kong L,Morais PC

更新日期：2014-10-15 00:00:00

abstract：:At present, there is a growing interest in the study of the neurotropic activity of polyunsaturated fatty acids ethanolamides (N-acylethanolamines). N-docosahexaenoylethanolamine (DHEA, synaptamide) is an endogenous metabolite and structural analogue of anandamide, a widely studied endocannabinoid derived from arachid...

journal_title：Scientific reports

authors： Ponomarenko AI,Tyrtyshnaia AA,Pislyagin EA,Dyuizen IV,Sultanov RM,Manzhulo IV

更新日期：2021-01-12 00:00:00

abstract：:Antibody humanization is a key step in the preclinical phase of the development of therapeutic antibodies, originally developed and tested in non-human models (most typically, in mouse). The standard technique of Complementarity-Determining Regions (CDR) grafting into human Framework Regions of germline sequences has ...

journal_title：Scientific reports

authors： Clavero-Álvarez A,Di Mambro T,Perez-Gaviro S,Magnani M,Bruscolini P

更新日期：2018-10-04 00:00:00

abstract：:We have prepared and studied a family of cyanobiphenyl dimers with varying linking groups with a view to exploring how molecular structure dictates the stability of the nematic and twist-bend nematic mesophases. Using molecular modelling and 1D 1H NOESY NMR spectroscopy, we determine the angle between the two aromatic...

journal_title：Scientific reports

authors： Mandle RJ,Archbold CT,Sarju JP,Andrews JL,Goodby JW

更新日期：2016-11-07 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is a chronic disease, and dietary modification is a crucial part of disease management. Okara is a sustainable source of fibre-rich food. Most of the valorization research on okara focused more on the physical attributes instead of the possible health attributes. The fermentation of oka...

journal_title：Scientific reports

authors： Chan LY,Takahashi M,Lim PJ,Aoyama S,Makino S,Ferdinandus F,Ng SYC,Arai S,Fujita H,Tan HC,Shibata S,Lee CK

更新日期：2019-11-26 00:00:00

abstract：:Melimine and Mel4 are chimeric cationic peptides with broad-spectrum antimicrobial activity. They have been shown to be highly biocompatible in animal models and human clinical trials. The current study examined the mechanism of action of these two antimicrobial peptides against P. aeruginosa. The effect of the peptid...

journal_title：Scientific reports

authors： Yasir M,Dutta D,Willcox MDP

更新日期：2019-05-08 00:00:00

abstract：:Membranes with selective superwettability for oil/water separation have received significant attention during the past decades. Hierarchical structures and surface roughness are believed to improve the oil repellency and the stability of Cassie-Baxter state. Diatoms, unicellular photosynthetic algae, possess sophistic...

journal_title：Scientific reports

authors： Lo YH,Yang CY,Chang HK,Hung WC,Chen PY

更新日期：2017-05-03 00:00:00

abstract：:Brain metastasis is a significant unmet clinical problem in breast cancer treatment. It is always associated with poor prognosis and high morbidity. Recently, Slit2/Robo1 pathway has been demonstrated to be involved in the progression of breast carcinoma. However, until present, there are no convincing reports that su...

journal_title：Scientific reports

authors： Qin F,Zhang H,Ma L,Liu X,Dai K,Li W,Gu F,Fu L,Ma Y

更新日期：2015-09-24 00:00:00

abstract：:The aim of this study was to use functional neuroimaging to investigate whether oxytocin modulates the neural response to visual food cues in brain regions involved in the control of food intake. Twenty-four normal weight volunteers received intranasal oxytocin (24 IU) or placebo in a double-blind, randomized crossove...

journal_title：Scientific reports

authors： van der Klaauw AA,Ziauddeen H,Keogh JM,Henning E,Dachi S,Fletcher PC,Farooqi IS

更新日期：2017-06-27 00:00:00

abstract：:Methylmercury causes serious damage to the central nervous system, but the molecular mechanisms of methylmercury toxicity are only marginally understood. In this study, we used a gene-deletion mutant library of budding yeast to conduct genome-wide screening for gene knockouts affecting the sensitivity of methylmercury...

journal_title：Scientific reports

authors： Hwang GW,Murai Y,Takahashi T,Naganuma A

更新日期：2014-07-30 00:00:00

abstract：:Porphyry systems supply most copper and significant gold to our economy. Recent studies indicate that they are frequently associated with high Sr/Y magmatic rocks, but the meaning of this association remains elusive. Understanding the association between high Sr/Y magmatic rocks and porphyry-type deposits is essential...

journal_title：Scientific reports

authors： Chiaradia M,Ulianov A,Kouzmanov K,Beate B

更新日期：2012-01-01 00:00:00

abstract：:The spine flexibility creates one of the most significant challenges to proper positioning in radiation therapy of head and neck cancers. Even though existing immobilization techniques can reduce the positioning uncertainty, residual errors (2-3 mm along the cervical spine) cannot be mitigated by single translation-ba...

journal_title：Scientific reports

authors： Ostyn M,Wang S,Kim YS,Kim S,Yeo WH

更新日期：2019-10-07 00:00:00

abstract：:A species that requires sexual reproduction but cannot reproduce is doomed to extinction. The important increasing loss of species emphasizes the ecological significance of elucidating the effects of environmental stressors, such as pesticides, on reproduction. Despite its special reproductive behavior, the honey bee ...

journal_title：Scientific reports

authors： Kairo G,Provost B,Tchamitchian S,Ben Abdelkader F,Bonnet M,Cousin M,Sénéchal J,Benet P,Kretzschmar A,Belzunces LP,Brunet JL

更新日期：2016-08-23 00:00:00

abstract：:The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We exposed an organotypi...

journal_title：Scientific reports

authors： Morgan MM,Livingston MK,Warrick JW,Stanek EM,Alarid ET,Beebe DJ,Johnson BP

更新日期：2018-05-08 00:00:00

abstract：:It was previously demonstrated that microRNA-199a (miR-199a) was down-regulated in testicular germ cell tumor (TGCT) partially caused by hypermethylation of its promoter. miR-199a is encoded by two loci in the human genome, miR-199a-1 on chromosome (Chr) 19 and miR-199a-2 on Chr 1. Both loci encode the same miR-199a. ...

journal_title：Scientific reports

authors： Chen BF,Suen YK,Gu S,Li L,Chan WY

更新日期：2014-09-18 00:00:00

abstract：:Large classes of electronic, photonic, and acoustic crystals and quasi-crystals have been predicted to support topological wave-modes. Some of these modes are stabilized by certain symmetries but others occur as pure wave phenomena, hence they can be observed in many other media that support wave propagation. Surface ...

journal_title：Scientific reports

authors： Apigo DJ,Kanwal A,Palmieri J,Dobiszewski KF,Farrow RC,Thomas GA,Prodan EV,Prodan C

更新日期：2018-02-20 00:00:00

abstract：:High-precision radiotherapy (HPR) has established its important role in the treatment of tumors due to its precise dose distribution. Given its more complicated delivery process, HPR commonly requires more fraction delivery time (FDT). However, it is unknown whether it has an identical response of prolonged FDT on dif...

journal_title：Scientific reports

authors： Yao Q,Zheng R,Xie G,Liao G,Du S,Ren C,Li R,Lin X,Hu D,Yuan Y

更新日期：2015-03-13 00:00:00

abstract：:Rice (Oryza sativa L.) is one of the essential staple food crops and tillering, panicle branching and grain filling are three important traits determining the grain yield. Although miRNAs have been reported being regulating yield, no study has systematically investigated how miRNAs differentially function in high and ...

journal_title：Scientific reports

authors： Hu J,Zeng T,Xia Q,Qian Q,Yang C,Ding Y,Chen L,Wang W

更新日期：2018-05-31 00:00:00

abstract：:Molecular crystals demonstrate drastically different behavior in solid and liquid state, mainly due to their difference in structural frameworks. Therefore, designing of unique structured molecular compound which can work at both these interfaces has been a challenge. Here, we present remarkable 'molecular' property b...

journal_title：Scientific reports

authors： Mande HM,Ghalsasi PS

更新日期：2015-09-28 00:00:00

abstract：:We evaluated surgical outcomes of bilateral rectus (BLR) recession in patients with intermittent exotropia who underwent diagnostic monocular occlusion. Records of patients with intermittent exotropia who were preoperatively examined one-hour monocular occlusion and underwent BLR recession were reviewed retrospectivel...

journal_title：Scientific reports

authors： Lee JY,Song JE,Chang HR,Choi CY,Han SY

更新日期：2020-05-08 00:00:00

abstract：:This paper studies the social acceptability and feasibility of a focused protection strategy against coronavirus disease 2019 (COVID-19). We propose a control scheme to develop herd immunity while satisfying the following two basic requirements for a viable policy option. The first requirement is social acceptability:...

journal_title：Scientific reports

authors： Akamatsu T,Nagae T,Osawa M,Satsukawa K,Sakai T,Mizutani D

更新日期：2021-01-21 00:00:00

abstract：:Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-κB-mediated inflammatory response. We investigated later phases of TNF signaling, after the initial transient induction of inflammatory genes has subsided, in primary human macrophages. TNF signaling induced expression of late response gen...

journal_title：Scientific reports

authors： Huynh L,Kusnadi A,Park SH,Murata K,Park-Min KH,Ivashkiv LB

更新日期：2016-08-25 00:00:00

abstract：:The pressure dependence of the superconducting transition temperature (Tc) and unit cell metrics of tetragonal (NH3)yCs0.4FeSe were investigated in high pressures up to 41 GPa. The Tc decreases with increasing pressure up to 13 GPa, which can be clearly correlated with the pressure dependence of c (or FeSe layer spaci...

journal_title：Scientific reports

authors： Izumi M,Zheng L,Sakai Y,Goto H,Sakata M,Nakamoto Y,Nguyen HLT,Kagayama T,Shimizu K,Araki S,Kobayashi TC,Kambe T,Gu D,Guo J,Liu J,Li Y,Sun L,Prassides K,Kubozono Y

更新日期：2015-04-01 00:00:00

abstract：:This work reports the first study of current-driven magnetization noise in a single, nanometerscale, ferromagnetic (Co) particle, attached to normal metal leads by high-resistance tunneling junctions. As the tunnel current increases at low temperature, the magnetic switching field decreases, its probability distributi...

journal_title：Scientific reports

authors： Jiang W,Birk FT,Davidović D

更新日期：2013-01-01 00:00:00