Abstract：
INTRODUCTION:This study aimed to investigate dental pulp responses to novel bioactive glass (BG) pulp capping materials after direct pulp capping in vivo. METHODS:Novel BG pulp capping materials are composed of powder and fluid. The powder is BG (82.36% SiO2, 15.36% CaO, and 2.28% P2O5), and the fluid is provided in 2 kinds: (1) phosphate buffer solution (BG-PB) and (2) phosphate buffer solution with the addition of 1 wt% sodium alginate (BG-PB-SA). After mixing the powder and fluid, BG-PB and BG-PB-SA were prepared. Cavities with mechanical pulp exposure were prepared on maxillary first molars of Wistar rats. The exposures were randomly capped with BG-PB, BG-PB-SA, or mineral trioxide aggregate (MTA). After 1 (n = 6) and 4 weeks (n = 8), maxillary segments were obtained and prepared for histologic analysis with a scoring system. Statistical analysis was performed using the Kruskal-Wallis and Mann-Whitney U tests with the significance set at .05. RESULTS:After 1 week, few inflammatory cells were present in the BG-PB, BG-PB-SA, and MTA groups. Moreover, a thin layer of newly generated matrix was observed in most specimens. After 4 weeks, all specimens from the 3 groups formed a heavy dentin bridge. BG-PB and BG-PB-SA groups exhibited no or slight inflammatory response, whereas the MTA group exhibited a slight to moderate inflammatory response. No significant difference was observed in pulp inflammation and dentin formation among the 3 groups at either time point (P > .05). CONCLUSIONS:When used as a pulp capping agent, BG-PB and BG-PB-SA had similar favorable cellular and inflammatory pulp responses to those of MTA. Therefore, BG is a promising pulp capping material.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Long Y,Liu S,Zhu L,Liang Q,Chen X,Dong Ydoi
10.1016/j.joen.2017.03.011subject
Has Abstractpub_date
2017-10-01 00:00:00pages
1647-1650issue
10eissn
0099-2399issn
1878-3554pii
S0099-2399(17)30301-1journal_volume
43pub_type
杂志文章abstract：INTRODUCTION:Enterococcus faecalis is a frequently isolated microorganism in persistent periapical lesion or secondary infection. However, no evidence has demonstrated that E. faecalis induced inflammation directly in the apical area. This study aimed to explore the mechanism of the inflammatory responses of human peri...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.08.028
更新日期：2015-12-01 00:00:00
abstract：INTRODUCTION:The lysyl oxidase (LOX) family is an emerging family of amine oxidases responsible for the formation of collagen fibrils in the extracellular matrix. To date, 5 LOX family genes have been identified in humans, encoding LOX and LOX-like proteins (LOXL, LOXL2, LOXL3, and LOXL4). The goal of this study was to...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2012.03.014
更新日期：2012-06-01 00:00:00
abstract：:This study investigated the retreatment effectiveness of .04 Taper nickel-titanium rotary ProFiles. Thirty extracted single-rooted anterior teeth were instrumented and obturated with gutta-percha/Roth's Sealer using lateral condensation. They were distributed into three groups of 10 each. Retreatment for group A was d...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200002000-00010
更新日期：2000-02-01 00:00:00
abstract：:Pulp regeneration is a biologic process occurring under specific circumstances. An endodontic treatment modality to accomplish pulp regeneration has emerged based on the response of undifferentiated cells that are often referred to as stem cells. The treatment itself is currently empirical based on clinicians' thought...
journal_title：Journal of endodontics
pub_type： 杂志文章,评审
doi：10.1016/j.joen.2014.01.017
更新日期：2014-04-01 00:00:00
abstract：:The purpose of this study was to examine the effect of the smear layer on apical microleakage over 16 wk. One hundred and four extracted human teeth were assigned to four groups treated as follows: group A1--smear layer was left intact and canals were obturated with gutta-percha and Roth 811; group A2--smear layer was...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(99)80010-7
更新日期：1999-02-01 00:00:00
abstract：INTRODUCTION:The aim of the present study was to compare sonic activation using EDDY (VDW, Munich, Germany), passive ultrasonic irrigation (PUI), and mechanical activation using the XPendo Finisher (FKG Dentaire, La Chaux-des-Fonds, Switzerland) for the removal of calcium hydroxide from artificial grooves in straight r...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2018.11.001
更新日期：2019-03-01 00:00:00
abstract：INTRODUCTION:This in vitro study compared the performance of the XP-endo Shaper (XP; FKG, La Chaux-de-Fonds, Switzerland) in curved canals when used with a higher speed (3000 rpm) without a glide path with the manufacturer's protocol. METHODS:Twenty extracted mandibular molars with separate mesial curved canals were m...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.10.014
更新日期：2020-01-01 00:00:00
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journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200109000-00004
更新日期：2001-09-01 00:00:00
abstract：:Removing posts from root canals prior to endodontic retreatment is often a challenge. The Gonon post removing system (Thomas Extracteur De Pivots; FFDM-Pneumat, Bourges, France) is safe and efficient and can be used for anterior, bicuspid, and even molar teeth. The Gonon system is illustrated with one clinical case. ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(89)80200-6
更新日期：1989-11-01 00:00:00
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journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(99)80278-7
更新日期：1999-06-01 00:00:00
abstract：INTRODUCTION:An ideal root canal sealer creates a bacteria-resistant seal and exhibits antimicrobial activity, biocompatibility, and osteoconductivity. The aim of this study was to assess the effects of 3 root canal sealers on cell viability, inflammatory response, and osteogenic potential in MC3T3-E1 cells. METHODS:A...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2018.09.006
更新日期：2019-01-01 00:00:00
abstract：:The purpose of this study was to evaluate the durability of insulated probes designed to be used with the Endocater Apex Locator when put through multiple cleaning and autoclaving cycles. The manufacturer has reported that the plastic coating on the probes is reliable with normal use and sterilizable up to a maximum o...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81502-5
更新日期：1993-08-01 00:00:00
abstract：INTRODUCTION:The objective of this ex vivo study was to compare the efficacy of passive ultrasonic irrigation (PUI) versus a new activation system using reciprocating motion (EasyClean [EC]; Easy Equipamentos Odontológicos, Belo Horizonte, Brazil) to remove debris from the root canal walls at 6 predetermined apical lev...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.01.016
更新日期：2016-04-01 00:00:00
abstract：INTRODUCTION:An ideal orthograde or retrograde filling material should seal the pathways of communication between the root canal system and its surrounding tissues. It should also be nontoxic, noncarcinogenic, nongenotoxic, biocompatible, insoluble in tissue fluids, and dimensionally stable. Mineral trioxide aggregate ...
journal_title：Journal of endodontics
pub_type： 杂志文章,评审
doi：10.1016/j.joen.2009.09.006
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:Root fusion is an anatomic variation in maxillary second molars (MSMs); however, the nature of this canal morphology as it relates to its root anatomy has not been fully clarified. The purpose of this study was to investigate the relationship between features of fused roots and root canal anatomy in MSMs u...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2013.10.035
更新日期：2014-06-01 00:00:00
abstract：INTRODUCTION:Experimental studies show that dental pulp cells respond unfavorably to contact with resin composite restorative material. Hypothetically, in a random population, the frequency of apical periodontitis should be higher for teeth restored with resin composite than with amalgam. Therefore, the aim was to comp...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.05.002
更新日期：2014-09-01 00:00:00
abstract：:Microbial control--fundamental to healing of apical periodontitis--is central to endodontic practice. The effectiveness of antibacterial measures is generally monitored (in clinical research studies) by microbiological root canal sampling (MRS), which is often used as a predictor for healing. This article addresses th...
journal_title：Journal of endodontics
pub_type： 杂志文章,评审
doi：10.1016/j.joen.2006.11.006
更新日期：2007-03-01 00:00:00
abstract：INTRODUCTION:Warm vertically compacted gutta-percha obturation techniques use root canal sealers that are heated during the obturation. This study aims at investigating the suitability of selected sealers with warm gutta-percha obturation techniques. METHODS:The composition of an experimental sealer (Septodont; Saint ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.06.007
更新日期：2015-01-01 00:00:00
abstract：:Inflammation of pulp tissue appears as a consequence of caries progression. Its main characteristic is inflamed infiltrate whose cells contain lymphocytes. CD44 is a widely expressed adhesion molecule present in several body cells such as leukocytes and parenchymatous cells, including endothelial cells, epithelial cel...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2007.05.022
更新日期：2007-10-01 00:00:00
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journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2011.10.018
更新日期：2012-02-01 00:00:00
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journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.07.024
更新日期：2014-12-01 00:00:00
abstract：:This study investigated the possibility of saliva recontamination occurring between the root canal wall and sealer through dentinal tubules exposed after the cementum was removed at the cervical level by root planing and treatment with citric acid. Thirty-four extracted human maxillary anterior teeth were randomly pla...
journal_title：Journal of endodontics
pub_type： 杂志文章
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更新日期：1996-11-01 00:00:00
abstract：INTRODUCTION:The effect of endodontic involvement on tooth loss has not been quantified, so the present study aimed to assess this relationship after controlling for other relevant risk factors for tooth loss. METHODS:We analyzed data from 791 participants (18,798 teeth) in the Veterans Affairs Dental Longitudinal Stu...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.08.051
更新日期：2010-12-01 00:00:00
abstract：:A tight and long-lasting seal of root-end fillings is of prime clinical importance. A hundred standard bovine root sections, each 3 mm high and with a central pulp lumen of 2.6 mm in diameter, were filled with five commonly used or potential root-end filling materials. At 24 h, or at 3, 6, or 12 months after filling, ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(98)80077-0
更新日期：1998-08-01 00:00:00
abstract：:Taurodontism is a morphoanatomical change in the shape of a tooth, which usually occurs in multirooted teeth. An enlarged body and pulp chamber, as well as apical displacement of the pulpal floor, are characteristic features. Endodontic treatment of a taurodont tooth is challenging, because it requires special care in...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200305000-00009
更新日期：2003-05-01 00:00:00
abstract：:The aim of this study was to test the effect of different concentrations of sodium hypochlorite, chlorhexidine, and cetrimide on the following bacterial strains: Facultative aerobes-anaerobes: Candida albicans ATCC 10231; Enterococcus faecalis ATCC 29212; Escherichia coli ATCC 25,922; Pseudomonas aeruginosa ATCC 27,85...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81170-2
更新日期：1999-05-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to examine the effect of pulp cell injection on host angiogenesis during wound healing. METHODS:Pulp cells were isolated from extracted premolars by the outgrowth method. Fluorescently labeled pulp cells or phosphate-buffered saline were locally injected into a mouse wound healin...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2013.01.011
更新日期：2013-06-01 00:00:00
abstract：INTRODUCTION:Anesthetic efficacy of inferior alveolar nerve block decreases in patients with irreversible pulpitis. It was hypothesized that premedication with nonsteroidal anti-inflammatory drugs might improve the success rates in patients with inflamed pulps. METHODS:Sixty-nine adult volunteers who were actively exp...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2009.11.010
更新日期：2010-03-01 00:00:00
abstract：INTRODUCTION:The aim of this retrospective study was to evaluate the outcome of endodontic microsurgery and to examine prognostic factors related to healing. METHODS:The clinical records of all patients who had undergone endodontic microsurgery from 1997-2003 at the National Dental Centre of Singapore were examined. T...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.04.005
更新日期：2014-08-01 00:00:00
abstract：INTRODUCTION:Previous studies in patients with irreversible pulpitis have reported increased success of the inferior alveolar nerve block (IANB) using premedication with ketorolac. Preemptive nitrous oxide administration has also shown an increase in the success of the IANB. Recently, ketorolac has been made available ...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2017.09.011
更新日期：2018-01-01 00:00:00
