Pathway-based expression profiling of benign prostatic hyperplasia and prostate cancer delineates an immunophilin molecule associated with cancer progression.

abstract：:Enterovirus A71 (EV-A71), which belongs to the family Picornaviridae, can invade the central nervous system (CNS) and cause severe CNS complications or death. The EV-A71 antigen has been detected in the neurons in the brains of humans who died from EV-A71 infection. However, the effect of EV-A71 infection on human neu...

journal_title：Scientific reports

authors： Lin JY,Huang HI

更新日期：2020-09-17 00:00:00

abstract：:Effective quality assurance is essential in any screening programme. This article provides a unique insight into key quality indicators of five rounds of the first population-based colorectal cancer screening programme implemented in Spain (2000-2012), providing the results according to the type of screening (prevalen...

journal_title：Scientific reports

authors： Binefa G,Garcia M,Milà N,Fernández E,Rodríguez-Moranta F,Gonzalo N,Benito L,Clopés A,Guardiola J,Moreno V

更新日期：2016-01-20 00:00:00

abstract：:In this report, we demonstrate mid-infrared dual-waveband (i.e., ~3 μm and ~2 μm) pulses from a cascaded gain-switched Ho3+-doped ZBLAN fiber laser by the use of hybrid pumping of 1150 nm CW and pulse LDs for the first time. Stable ~3 μm gain-switched pulses with the maximum output power 262.14 mW and shortest pulse d...

journal_title：Scientific reports

authors： Luo H,Li J,Zhu C,Lai X,Hai Y,Liu Y

更新日期：2017-12-04 00:00:00

abstract：:The study of the preparation phase of large earthquakes is essential to understand the physical processes involved, and potentially useful also to develop a future reliable short-term warning system. Here we analyse electron density and magnetic field data measured by Swarm three-satellite constellation for 4.7 years,...

journal_title：Scientific reports

authors： De Santis A,Marchetti D,Pavón-Carrasco FJ,Cianchini G,Perrone L,Abbattista C,Alfonsi L,Amoruso L,Campuzano SA,Carbone M,Cesaroni C,De Franceschi G,De Santis A,Di Giovambattista R,Ippolito A,Piscini A,Sabbagh D,Soldani M

更新日期：2019-12-30 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) is a substantial burden throughout Asia, but the effects of temperature pattern on HFMD risk are inconsistent. To quantify the effect of temperature on HFMD incidence, Wuhan was chosen as the study site because of its high temperature variability and high HFMD incidence. Daily serie...

journal_title：Scientific reports

authors： Huang J,Chen S,Wu Y,Tong Y,Wang L,Zhu M,Hu S,Guan X,Wei S

更新日期：2018-01-31 00:00:00

abstract：:Fermentation is the key process to produce the special color of congou black tea. The machine vision technology is applied to detect the color space changes of black tea's color in RGB, Lab and HSV, and to find out its relevance to black tea's fermentation quality. And then the color feature parameter is used as input...

journal_title：Scientific reports

authors： Dong C,Liang G,Hu B,Yuan H,Jiang Y,Zhu H,Qi J

更新日期：2018-07-12 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is the only blood based protein biomarker at present, used for preoperative screening of advanced colorectal cancer (CRC) patients to determine the appropriate curative treatments and post-surveillance screening for tumour recurrence. Current diagnostics for CRC detection have several li...

journal_title：Scientific reports

authors： Shamsuddin SH,Jayne DG,Tomlinson DC,McPherson MJ,Millner PA

更新日期：2021-01-12 00:00:00

abstract：:Gold nanoparticles (GNP) have been intensively investigated for applications in cancer imaging and therapy. Most imaging studies focused on microscopic imaging. Their potential as optical imaging probes for whole body small animal imaging has rarely been explored. Taking advantage of their surface plasmon resonance (S...

journal_title：Scientific reports

authors： Xu K,Shi J,Pourmand A,Udayakumar TS,Dogan N,Zhao W,Pollack A,Yang Y

更新日期：2018-06-19 00:00:00

abstract：:Lon is an essential, multitasking AAA(+) protease regulating many cellular processes in species across all kingdoms of life. Altered expression levels of the human mitochondrial Lon protease (hLon) are linked to serious diseases including myopathies, paraplegia, and cancer. Here, we present the first 3D structure of f...

journal_title：Scientific reports

authors： Kereïche S,Kováčik L,Bednár J,Pevala V,Kunová N,Ondrovičová G,Bauer J,Ambro Ľ,Bellová J,Kutejová E,Raška I

更新日期：2016-09-16 00:00:00

abstract：:Two-dimensional nanostructures with controllable magnetic and electronic properties are desirable for their versatile applications in quantum devices. Here, we present a first-principles design on their magnetic and electronic switching controlled by tension. We find that hydrogenated VTe2 monolayer experiences a tran...

journal_title：Scientific reports

authors： Pan H

更新日期：2014-12-17 00:00:00

abstract：:A frequency reconfigurable dipole antenna based on a silicon radiator is presented. The silicon radiator is activated with the aid of highly dense solid-state plasma by injecting carriers into the intrinsic region of p-i-n diodes. The fabrication and design guideline of the reconfigurable dipole antenna with this plas...

journal_title：Scientific reports

authors： Kim DJ,Jo ES,Cho YK,Hur J,Kim CK,Kim CH,Park B,Kim D,Choi YK

更新日期：2018-10-09 00:00:00

abstract：:The South Asian subcontinent is characterized by a complex history of human migrations and population interactions. In this study, we used genome-wide data to provide novel insights on the demographic history and population relationships of six Indo-European populations from the Indian State of West Maharashtra. The s...

journal_title：Scientific reports

authors： Debortoli G,Abbatangelo C,Ceballos F,Fortes-Lima C,Norton HL,Ozarkar S,Parra EJ,Jonnalagadda M

更新日期：2020-06-22 00:00:00

abstract：:Voltage gated sodium channels are key players in aberrant pain signaling and sensitization of nociceptors after peripheral nerve injury. The extent to which sodium channel activity after injury contributes to synaptic transmission at the first pain synapse however remains unclear. To investigate the effect of axotomy ...

journal_title：Scientific reports

authors： Vysokov N,McMahon SB,Raouf R

更新日期：2019-09-09 00:00:00

abstract：:Spiders can cause trophic cascades affecting litter decomposition rates. However, it remains unclear how spiders with different foraging strategies influence faunal communities, or present cascading effects on decomposition. Furthermore, increased dry periods predicted in future climates will likely have important con...

journal_title：Scientific reports

authors： Liu S,Chen J,Gan W,Schaefer D,Gan J,Yang X

更新日期：2015-07-23 00:00:00

abstract：:Among the 146 patients enrolled in the Korean FH registry, 83 patients who had undergone appropriate LLT escalation and were followed-up for ≥ 6 months were analyzed for pathogenic variants (PVs). The achieved percentage of expected low-density lipoprotein-cholesterol (LDL-C) reduction (primary variable) and achieveme...

journal_title：Scientific reports

authors： Kim H,Lee CJ,Pak H,Kim DI,Rhee MY,Lee BK,Ahn Y,Cho BR,Woo JT,Hur SH,Jeong JO,Lee JH,Lee SH

更新日期：2020-11-09 00:00:00

abstract：:Natural Bacillus isolates generate limited amounts of surfactin (<10% of their biomass), which functions as an antibiotic or signalling molecule in inter-/intra-specific interactions. However, overproduction of surfactin in Bacillus amyloliquefaciens MT45 was observed at a titre of 2.93 g/l, which is equivalent to hal...

journal_title：Scientific reports

authors： Zhi Y,Wu Q,Xu Y

更新日期：2017-01-23 00:00:00

abstract：:Efficiently detecting and characterizing individual spins in solid-state hosts is an essential step to expand the fields of quantum sensing and quantum information processing. While selective detection and control of a few 13C nuclear spins in diamond have been demonstrated using the electron spin of nitrogen-vacancy ...

journal_title：Scientific reports

authors： Oh H,Yun J,Abobeih MH,Jung KH,Kim K,Taminiau TH,Kim D

更新日期：2020-09-10 00:00:00

abstract：:Are you walking at me? Biological movement and the encoding of its motion and orientation. A person's motion conveys a wealth of information that ranges from the complex, such as intention or emotional state, to the simple, such as direction of locomotion. How we recognise and recover people's motion is addressed by m...

journal_title：Scientific reports

authors： Benton CP,Thirkettle M,Scott-Samuel NE

更新日期：2016-02-29 00:00:00

abstract：:This study investigates the effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on persistent post-concussion syndrome (PCS). The study design was a randomized (coin toss), placebo controlled, and double-blind study. Thirty-seven participants with PCS were assessed for eligibility; 22 were randomised and 18 ...

journal_title：Scientific reports

authors： Moussavi Z,Suleiman A,Rutherford G,Ranjbar Pouya O,Dastgheib Z,Zhang W,Salter J,Wang X,Mansouri B,Lithgow B

更新日期：2019-04-02 00:00:00

abstract：:Anisotropic Fe3O4 nanoparticle and a series of its graphene composites have been successfully prepared as high-frequency absorbers. The crystal structure, morphology and magnetic property of the samples were detailed characterized through X-ray diffractometer (XRD), transmission electron microscopy (TEM) and vibrating...

journal_title：Scientific reports

authors： Yin Y,Zeng M,Liu J,Tang W,Dong H,Xia R,Yu R

更新日期：2016-05-04 00:00:00

abstract：:Diabetes mellitus (DM) is associated with higher risk of tendinopathy, which reduces tolerance to exercise and functional activities and affects lifestyle and glycemic control. Expression of tendon-related genes and matrix metabolism in tenocytes are essential for maintaining physiological functions of tendon. However...

journal_title：Scientific reports

authors： Wu YF,Wang HK,Chang HW,Sun J,Sun JS,Chao YH

更新日期：2017-03-07 00:00:00

abstract：:An early bottleneck in the rapid isolation of new antibody fragment binders using in vitro library approaches is the inertia encountered in acquiring and preparing soluble antigen fragments. In this report, we describe a simple, yet powerful strategy that exploits the properties of the SpyCatcher/SpyTag (SpyC/SpyT) co...

journal_title：Scientific reports

authors： Fierle JK,Abram-Saliba J,Brioschi M,deTiani M,Coukos G,Dunn SM

更新日期：2019-09-06 00:00:00

abstract：:Organ regenerative therapy aims to reproduce fully functional organs to replace organs that have been lost or damaged as a result of disease, injury, or aging. For the fully functional regeneration of ectodermal organs, a concept has been proposed in which a bioengineered organ is developed by reproducing the embryoni...

journal_title：Scientific reports

authors： Asakawa K,Toyoshima KE,Ishibashi N,Tobe H,Iwadate A,Kanayama T,Hasegawa T,Nakao K,Toki H,Noguchi S,Ogawa M,Sato A,Tsuji T

更新日期：2012-01-01 00:00:00

abstract：:It is recognized that T helper 2 (Th2) polarization plays a critical role in a large number of immune disorders. Yet, the remedies for reconciling the established Th2 polarization are still limited currently. Published data indicate that micro RNA-17-92 cluster is associated with the skewed immune response; 25 vitamin...

journal_title：Scientific reports

authors： Yu ZJ,Zeng L,Luo XQ,Geng XR,Xu R,Chen K,Yang G,Luo X,Liu ZQ,Liu ZG,Liu DB,Yang PC,Li HB

更新日期：2017-04-03 00:00:00

abstract：:Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein that controls the cellular response to oxidative stress and possesses DNA-repair functions. It has important roles in the progression and outcomes of various diseases; however, its function and therapeutic prospects with respect to kidney injury ...

journal_title：Scientific reports

authors： Maruyama K,Nakagawa N,Aonuma T,Saito Y,Hayasaka T,Kano K,Horiuchi K,Takehara N,Kawabe JI,Hasebe N

更新日期：2019-05-24 00:00:00

abstract：:The MADS-box transcription factors play essential roles in many physiological and biochemical processes of plants, especially in fruit ripening. Here, a tomato MADS-box gene, SlCMB1, was isolated. SlCMB1 expression declined with the fruit ripening from immature green to B + 7 (7 days after Breaker) fruits in the wild ...

journal_title：Scientific reports

authors： Zhang J,Hu Z,Yao Q,Guo X,Nguyen V,Li F,Chen G

更新日期：2018-02-21 00:00:00

abstract：:Detection of nitroaromatic explosives with high sensitivity and selectivity is extremely important for civilian and military safety. Here, we report the synthesis and multimodal sensing applications of an emissive alanine based dansyl tagged copolymer P(MMA-co-Dansyl-Ala-HEMA) (DCP), synthesized by RAFT copolymerizati...

journal_title：Scientific reports

authors： Kumar V,Maiti B,Chini MK,De P,Satapathi S

更新日期：2019-05-13 00:00:00

abstract：:Friction is a major inhibitor in almost every mechanical system. Enlightened by the Leidenfrost effect - a droplet can be levitated by its own vapor layer on a sufficiently hot surface - we demonstrate for the first time that a small cart can also be levitated by Leidenfrost vapor. The levitated cart can carry certain...

journal_title：Scientific reports

authors： Hashmi A,Xu Y,Coder B,Osborne PA,Spafford J,Michael GE,Yu G,Xu J

更新日期：2012-01-01 00:00:00

abstract：:Light-inducible gene regulation has great potential for remote and noninvasive control of the fate and function of target cells. One method to achieve such control is delivery of heat shock protein (HSP) promoter-driven protein expression vectors and photothermal heaters into the cells, followed by activation by illum...

journal_title：Scientific reports

authors： Nakatsuji H,Kawabata Galbraith K,Kurisu J,Imahori H,Murakami T,Kengaku M

更新日期：2017-07-05 00:00:00

abstract：:Enzyme replacement therapies have revolutionized patient treatment for multiple rare lysosomal storage diseases but show limited effectiveness for addressing pathologies in "hard-to-treat" organs and tissues including brain and bone. Here we investigate the plant lectin RTB as a novel carrier for human lysosomal enzym...

journal_title：Scientific reports

authors： Acosta W,Ayala J,Dolan MC,Cramer CL

更新日期：2015-09-18 00:00:00