Dimerization in tailoring uptake efficacy of the HSV-1 derived membranotropic peptide gH625.

abstract：:Artificial interface anisotropy is demonstrated in alternating Co/Pt and Co/Pd stripe patterns, providing a means of forming magnetic anisotropy using lithography. In-plane hysteresis loops measured along two principal directions are explained in depth by two competing shape and interface anisotropies, thus confirming...

journal_title：Scientific reports

authors： Kim SN,Nam YJ,Kim YD,Choi JW,Lee H,Lim SH

更新日期：2016-05-24 00:00:00

abstract：:Continuous gas-phase synthesis of nanoparticles is associated with rapid agglomeration, which can be a limiting factor for numerous applications. In this report, we challenge this paradigm by providing experimental evidence to support that gas-phase methods can be used to produce ultrapure non-agglomerated "singlet" n...

journal_title：Scientific reports

authors： Feng J,Biskos G,Schmidt-Ott A

更新日期：2015-10-29 00:00:00

abstract：:Cancer cachexia is a complex multi-organ syndrome characterized by body weight loss, weakness, muscle atrophy and fat depletion. With a prevalence of 1 million people in Europe and only limited therapeutic options, there is a high medical need for new approaches to treat cachexia. Our latest results highlighted microb...

journal_title：Scientific reports

authors： Pötgens SA,Brossel H,Sboarina M,Catry E,Cani PD,Neyrinck AM,Delzenne NM,Bindels LB

更新日期：2018-08-17 00:00:00

abstract：:By using a half soap bubble heated from below, we obtain large isolated single vortices whose properties as well as their intensity are measured under different conditions. By studying the effects of rotation of the bubble on the vortex properties, we found that rotation favors vortices near the pole. Rotation also in...

journal_title：Scientific reports

authors： Meuel T,Xiong YL,Fischer P,Bruneau CH,Bessafi M,Kellay H

更新日期：2013-12-13 00:00:00

abstract：:Acute Ischemic Stroke (AIS) in the young is increasing in prevalence and the largest subtype within this cohort is cryptogenic. To curb this trend, new ways of defining cryptogenic stroke and associated risk factors are needed. We aimed to gain insights into the presence or absence of cardiovascular risk factors in ca...

journal_title：Scientific reports

authors： Dardick JM,Flomenbaum D,Labovitz DL,Cheng N,Liberman AL,Esenwa C

更新日期：2021-01-11 00:00:00

abstract：:In the present work, the mechanisms involved in the recently reported antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring viraemia of carp rhabdovirus (SVCV) in fish are explored. The results neither indicate blocking of the attachment or the binding step of the viral replicatio...

journal_title：Scientific reports

authors： Bello-Perez M,Pereiro P,Coll J,Novoa B,Perez L,Falco A

更新日期：2020-01-17 00:00:00

abstract：:Imputation is a computational method based on the principle of haplotype sharing allowing enrichment of genome-wide association study datasets. It depends on the haplotype structure of the population and density of the genotype data. The 1000 Genomes Project led to the generation of imputation reference panels which h...

journal_title：Scientific reports

authors： Ahmad M,Sinha A,Ghosh S,Kumar V,Davila S,Yajnik CS,Chandak GR

更新日期：2017-07-27 00:00:00

abstract：:The long-term survival of relict populations depends on the accessibility of appropriate sites (microrefugia). In recent times, due to the mass extinction of rare species that has resulted from the loss of natural habitats, the question is - Are there any human-made sites that can act as refugial habitats? We examined...

journal_title：Scientific reports

authors： Zielińska KM,Kiedrzyński M,Grzyl A,Rewicz A

更新日期：2016-08-18 00:00:00

abstract：:In social interactions, including cooperation and conflict, individuals can adjust their behaviour over the shorter term through learning within a generation, and natural selection can change behaviour over the longer term of many generations. Here we investigate the evolution of cognitive bias by individuals investin...

journal_title：Scientific reports

authors： Leimar O,McNamara JM

更新日期：2019-11-08 00:00:00

abstract：:Bisphenol A (BPA) is widely used in the manufacture of plastics and epoxy resins and is prevalent in the aquatic environment. BPA disrupts endocrine pathways in fish, but the long-term developmental implications are unknown. We demonstrate that BPA deposition in the eggs of rainbow trout (Oncorhynchus mykiss), an ecol...

journal_title：Scientific reports

authors： Sadoul B,Birceanu O,Aluru N,Thomas JK,Vijayan MM

更新日期：2017-10-26 00:00:00

abstract：:The potential angiogenic effect of roxarsone, a feed additive widely used to promote animal growth worldwide, was demonstrated recently. We explored the mechanism of vascular endothelial growth factor (VEGF) and its receptor (VEGFR) in roxarsone promotion of rat vascular endothelial cells (ECs) and B16F10 mouse xenogr...

journal_title：Scientific reports

authors： Chen S,Xu J,Wei Q,Zhao Z,Chen X,Cui H,Zhang Y

更新日期：2019-11-22 00:00:00

abstract：:ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the ARTs that catalyse ...

journal_title：Scientific reports

authors： Rakhimova A,Ura S,Hsu DW,Wang HY,Pears CJ,Lakin ND

更新日期：2017-03-02 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Kamath PL,Manlove K,Cassirer EF,Cross PC,Besser TE

更新日期：2020-04-22 00:00:00

abstract：:The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5' capping, splicing and polyadenylation. Therefore to facilitate expression...

journal_title：Scientific reports

authors： Tunnicliffe RB,Tian X,Storer J,Sandri-Goldin RM,Golovanov AP

更新日期：2018-10-09 00:00:00

abstract：:Dairy cows are often fed a high-concentrate (HC) diet to meet lactation demands; however, long-term concentrate feeding is unhealthy and decreases milk fat. Therefore, we investigated the effects of liver lipid metabolism on milk fat synthesis. Ten lactating Holstein cows were assigned randomly into HC and LC (low-con...

journal_title：Scientific reports

authors： Li L,Cao Y,Xie Z,Zhang Y

更新日期：2017-03-13 00:00:00

abstract：:To date, there is only scarce evidence for a considerable association of subjective and objective stress measures, which might be attributable to method bias (e.g., confounding) and/or asynchrony of their temporal changes. To validate different subjective stress measures by a physiological measure of long-term stress ...

journal_title：Scientific reports

authors： Weckesser LJ,Dietz F,Schmidt K,Grass J,Kirschbaum C,Miller R

更新日期：2019-01-31 00:00:00

abstract：:We present two transmission-mode dielectric Fresnel-Zone Plate Lens (FZPL) antennas for use within the V-band spectrum. The proposed FZPs are realized via pure plastic material using two different additive manufacturing processes. The proposed FZP lenses are designed with half (λ/2) and quarter (λ/4) phase correction ...

journal_title：Scientific reports

authors： Pourahmadazar J,Denidni TA

更新日期：2018-03-28 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Prywer J,Torzewska A

更新日期：2020-01-27 00:00:00

abstract：:Mountain glaciers form landscapes with U-shaped valleys, roche moutonées and overdeepenings through bedrock erosion. However, little evidence for active glacial carving has been provided particularly for areas above the Equilibrium Line Altitude (ELA) where glaciers originate. This is mainly due to our lack of informa...

journal_title：Scientific reports

authors： Nishiyama R,Ariga A,Ariga T,Lechmann A,Mair D,Pistillo C,Scampoli P,Valla PG,Vladymyrov M,Ereditato A,Schlunegger F

更新日期：2019-05-06 00:00:00

abstract：:Adverse maternal environments, such as diabetes and obesity, impair placental mitochondrial function, which affects fetal development and offspring long-term health. The underlying mechanisms and effective interventions to abrogate such effect remain unclear. Our previous studies demonstrated impaired mitochondrial bi...

journal_title：Scientific reports

authors： Jiang S,Teague AM,Tryggestad JB,Jensen ME,Chernausek SD

更新日期：2020-05-20 00:00:00

abstract：:We developed a spongy-like porous polymer (spongy monolith) consisting of poly(ethylene-co-glycidyl methacrylate) with continuous macropores that allowed efficient in situ reaction between the epoxy groups and proteins of interest. Immobilization of protein A on the spongy monolith enabled high-yield collection of imm...

journal_title：Scientific reports

authors： Kubota K,Kubo T,Tanigawa T,Naito T,Otsuka K

更新日期：2017-03-14 00:00:00

abstract：:Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and proteins may be one important factor contributing to developmental failure in somatic cell cloned embryos. In the present study, we found microRNA-449b (miR-449b) was highly expressed in sperm. Target gene predictions and experimen...

journal_title：Scientific reports

authors： Wang M,Gao Y,Qu P,Qing S,Qiao F,Zhang Y,Mager J,Wang Y

更新日期：2017-10-17 00:00:00

abstract：:Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could also contribute to u...

journal_title：Scientific reports

authors： Sato TK,Kawano S,Endo T

更新日期：2019-05-21 00:00:00

abstract：:Exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) share similar abnormal choroidal vasculature, but responses to treatments are different. In this study, we sequenced the whole HTRA1 gene and its promoter by direct sequencing in a Hong Kong Chinese PCV cohort. We identified r...

journal_title：Scientific reports

authors： Ng TK,Liang XY,Lai TY,Ma L,Tam PO,Wang JX,Chen LJ,Chen H,Pang CP

更新日期：2016-06-24 00:00:00

abstract：:Mycoplasma mobile, a fish pathogen, exhibits its own specialized gliding motility on host cells based on ATP hydrolysis. The special protein machinery enabling this motility is composed of surface and internal protein complexes. Four proteins, MMOBs 1630, 1660, 1670, and 4860 constitute the internal complex, including...

journal_title：Scientific reports

authors： Tulum I,Kimura K,Miyata M

更新日期：2020-03-02 00:00:00

abstract：:The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all organisms. In an evolutionary heartbeat, humans have taken control of their light environment with electric light. Humans are highly sensitive to light, yet most people now use light until bedtime. We evaluated the impact...

journal_title：Scientific reports

authors： Cain SW,McGlashan EM,Vidafar P,Mustafovska J,Curran SPN,Wang X,Mohamed A,Kalavally V,Phillips AJK

更新日期：2020-11-05 00:00:00

abstract：:A relation exists between network proximity of molecular entities in interaction networks, functional similarity and association with diseases. The identification of network regions associated with biological functions and pathologies is a major goal in systems biology. We describe a network diffusion-based pipeline f...

journal_title：Scientific reports

authors： Bersanelli M,Mosca E,Remondini D,Castellani G,Milanesi L

更新日期：2016-10-12 00:00:00

abstract：:Dibutyl phthalate (DBP) is well known as a high-priority pollutant. This study explored the impacts of DBP on the metabolic pathways of microbes in black soils in the short term (20 days). The results showed that the microbial communities were changed in black soils with DBP. In nitrogen cycling, the abundances of the...

journal_title：Scientific reports

authors： Xu W,You Y,Wang Z,Chen W,Zeng J,Zhao X,Su Y

更新日期：2018-02-08 00:00:00

abstract：:This paper presented a conformal smoothing theory, and smoothing capability evaluation was established on the proposed theory. According to pressure distribution model, processing parameters have been optimized and the CPP sample with a size of 340 × 340 mm was applied in conformal smoothing. The middle spatial freque...

journal_title：Scientific reports

authors： Song C,Zhang W,Shi F,Lin Z,Nie X

更新日期：2020-02-13 00:00:00

abstract：:The Irish Travellers are a population with a history of nomadism; consanguineous unions are common and they are socially isolated from the surrounding, 'settled' Irish people. Low-resolution genetic analysis suggests a common Irish origin between the settled and the Traveller populations. What is not known, however, i...

journal_title：Scientific reports

authors： Gilbert E,Carmi S,Ennis S,Wilson JF,Cavalleri GL

更新日期：2017-02-09 00:00:00