Effect of ethanol on the spontaneous transmitter release by nerve endings in the process of maturation.

abstract：BACKGROUND:Genetic influences on smoking cessation treatment outcome may be affected by pretreatment patient characteristics. Nicotine dependence is arguably the most salient clinical factor in smoking cessation. METHODS:In this secondary analysis of clinical trial data (N=793), we examined nicotine dependence severit...

journal_title：Drug and alcohol dependence

authors： Leventhal AM,Lee W,Bergen AW,Swan GE,Tyndale RF,Lerman C,Conti DV

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Contingency management (CM) is efficacious for reducing drug use, but it has rarely been applied to patients with severe and persistent mental health problems. This study evaluated the efficacy of CM for reducing cocaine use in psychiatric patients treated at a community mental health center. METHODS:Ninete...

journal_title：Drug and alcohol dependence

authors： Petry NM,Alessi SM,Rash CJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Injection drug users (IDUs) are at high-risk for hepatitis B virus (HBV) and HIV. Due to concerns about non-adherence to multi-dose vaccine regimens however, IDUs are severely under-immunized against HBV and have been excluded from phase III trials of multi-dose candidate HIV vaccines in the United States. ...

journal_title：Drug and alcohol dependence

authors： Seal KH,Kral AH,Lorvick J,McNees A,Gee L,Edlin BR

更新日期：2003-08-20 00:00:00

abstract：:Studies on ethanol-exposed animals have revealed changes in anionic phospholipids in brain membranes. The intention of this study was to investigate whether there was a similar effect on man. Assuming platelets to be an adequate model for CNS synaptosomes, concentration and fatty acid composition of anionic phospholip...

journal_title：Drug and alcohol dependence

authors： Alling C,Jönsson G,Gustavsson L,Jensen L,Simonsson P

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Substance use disorders (SUD) might concern as many as 8-15% of physicians. Previous studies suggest that self-diagnosis and self-medication are common practices among physicians. The aim of this review was to identify if barriers to seeking help and medical care for impaired physicians exist. We also aimed ...

journal_title：Drug and alcohol dependence

authors： Vayr F,Herin F,Jullian B,Soulat JM,Franchitto N

更新日期：2019-06-01 00:00:00

abstract：:The aim of the present study is to analyze whether the addition of propylthiouracil reverts the influence of ethanol on the development of periportal and pericentral hepatocytes and their nuclei in male albino mice. Propylthiouracil-treated animals showed decreased cellular and nuclear areas when compared with the con...

journal_title：Drug and alcohol dependence

authors： González-Reimers CE,Santolaria-Fernández FJ,González-Hernández T,Batista-López N,Gómez-Sirvent JL,Pérez-Delgado MM,Ferres-Torres R

更新日期：1988-02-01 00:00:00

abstract：:Little is known about the relative severity or typical sequence of Diagnostic and Statistical Manual (DSM-IV) symptoms of nicotine dependence. Using data from the National Comorbidity Study (NCS), the current study used a Rasch logistic item response model to assess the unidimensionality of the construct of nicotine d...

journal_title：Drug and alcohol dependence

authors： Strong DR,Kahler CW,Ramsey SE,Brown RA

更新日期：2003-11-24 00:00:00

abstract：BACKGROUND:Despite evidence that cannabinoid receptors are located in movement-related brain regions (e.g., basal ganglia, cerebral cortex, and cerebellum), and that chronic cannabis use is associated with structural and functional brain changes, little is known about the long-term effect of cannabis use on human movem...

journal_title：Drug and alcohol dependence

authors： Pearson-Dennett V,Todd G,Wilcox RA,Vogel AP,White JM,Thewlis D

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Alcohol abuse and dependence can be disabling disorders, but accurate information is lacking on the prevalence of current DSM-IV alcohol abuse and dependence and how this has changed over the past decade. The purpose of this study was to present nationally representative data on the prevalence of 12-month DS...

journal_title：Drug and alcohol dependence

authors： Grant BF,Dawson DA,Stinson FS,Chou SP,Dufour MC,Pickering RP

更新日期：2004-06-11 00:00:00

abstract：:Our objective was to examine the cost of long-term residential (LTR) and outpatient drug-free (ODF) treatments for cocaine-dependent patients participating in the Drug Abuse Treatment Outcome Studies (DATOS), calculate the tangible cost of crime to society, and determine treatment benefits. Subjects were 502 cocaine-d...

journal_title：Drug and alcohol dependence

authors： Flynn PM,Kristiansen PL,Porto JV,Hubbard RL

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Both cannabis use and alcohol use are elevated among people living with HIV, but few studies have investigated the relationship between cannabis use and alcohol use in this population. This study examined the longitudinal association between cannabis use and alcohol use among people living with HIV and explo...

journal_title：Drug and alcohol dependence

authors： Wardell JD,Shuper PA,Hendershot CS

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Few studies have tested the hypothesis that adolescent cannabis users show structural brain alterations in adulthood. The present study tested associations between prospectively-assessed trajectories of adolescent cannabis use and adult brain structure in a sample of boys followed to adulthood. METHODS:Data...

journal_title：Drug and alcohol dependence

authors： Meier MH,Schriber RA,Beardslee J,Hanson J,Pardini D

更新日期：2019-09-01 00:00:00

abstract：:Heroin is an illicit narcotic abused by millions of people worldwide. In our earlier studies we have shown that heroin intoxication changes the antioxidant status in human brain. In the present work we continued our studies by estimating the effect of heroin abuse on reduced glutathione (GSH) and enzymes related to th...

journal_title：Drug and alcohol dependence

authors： Gutowicz M,Kaźmierczak B,Barańczyk-Kuźma A

更新日期：2011-01-01 00:00:00

abstract：:Since 1981, the Alberta Alcohol and Drug Abuse Commission has been conducting a primary prevention program intended to alter the development of intoxicant use patterns in adolescents. The program uses an integrated set of approaches involving mass communications, face-to-face program elements, community action and sma...

journal_title：Drug and alcohol dependence

authors： Skirrow J

更新日期：1987-09-01 00:00:00

abstract：:Position preference, i.e., the tendency to drink from onelocation rather than the other, was found to be relatively unimportant in determining the drinking behavior of rats presented with a choice between water and a 7% (v/v) ethanol solution in typical two-bottle choice situations. It accounted for essentially none o...

journal_title：Drug and alcohol dependence

authors： Sinclair JD

更新日期：1976-06-01 00:00:00

abstract：:A single dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. This effect is probably mediated through effects of ethanol on acetylcholine release. Choline uptake has also been shown to be altered in ethanol-dependent animals, and these effects may be coupled to alterat...

journal_title：Drug and alcohol dependence

authors： Hunt WA,Majchrowicz E

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:This study describes the frequency and characteristics of aggression and/or violence in ambulance attendances involving alcohol, illicit and/or pharmaceutical drug use in Victoria, Australia between January 2012 and January 2017. METHODS:Patient characteristics, context, and substance use involvement in amb...

journal_title：Drug and alcohol dependence

authors： Coomber K,Curtis A,Vandenberg B,Miller PG,Heilbronn C,Matthews S,Smith K,Wilson J,Moayeri F,Mayshak R,Lubman DI,Scott D

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Although both men and women use e-cigarettes, most preclinical nicotine research has focused on its effects in male rodents following injection. The goals of the present study were to develop an effective e-cigarette nicotine delivery system, to compare results to those obtained after subcutaneous (s.c.) inj...

journal_title：Drug and alcohol dependence

authors： Lefever TW,Lee YO,Kovach AL,Silinski MA,Marusich JA,Thomas BF,Wiley JL

更新日期：2017-03-01 00:00:00

abstract：:The main question addressed by this paper is whether DSM-IV substance dependence diagnoses obtained from two different instruments (the semi-structured WHO Schedules for Clinical Assessment in Neuropsychiatry, SCAN and the highly structured WHO Composite International Diagnostic Interview--Substance Abuse Module, SAM)...

journal_title：Drug and alcohol dependence

authors： Compton WM,Cottler LB,Dorsey KB,Spitznagel EL,Mager DE

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Persistence and emergence of ADHD in adulthood are associated with substance problems. We investigate differential implications of ADHD course for tobacco, alcohol, or marijuana problems by sex, then whether substance misuse results from ADHD or contributes to it, through a twin differences design. METHODS:...

journal_title：Drug and alcohol dependence

authors： Elkins IJ,Saunders GRB,Malone SM,Wilson S,McGue M,Iacono WG

更新日期：2020-07-01 00:00:00

abstract：:A standardized questionnaire, with satisfactory retake item reliabilities and well established validities, was administered to a representative sample of female university students (N = 2366), drawn from Cairo and Ein-Shams Universities, both located in Greater Cairo. Results, relevant to demographic and drug related ...

journal_title：Drug and alcohol dependence

authors： Soueif MI,Hannourah MA,Darweesh ZA,el-Sayed AM,Yunis FA,Taha HS

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Although studies have shown a cross-sectional link between discrimination and smoking, the prospective influence of discrimination on smoking cessation has yet to be evaluated. Thus, the purpose of the current study was to determine the influence of everyday and major discrimination on smoking cessation amon...

journal_title：Drug and alcohol dependence

authors： Kendzor DE,Businelle MS,Reitzel LR,Castro Y,Vidrine JI,Mazas CA,Cinciripini PM,Lam CY,Adams CE,Correa-Fernández V,Cano MÁ,Wetter DW

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Stress is thought to contribute to both initiation and relapse to drug abuse. However, the mechanisms by which stress influences drug use are unclear. Interestingly, responses to acute administration of stimulant drugs resemble certain neuronal and hormonal responses to acute stress, and there is accumulatin...

journal_title：Drug and alcohol dependence

authors： Hamidovic A,Childs E,Conrad M,King A,de Wit H

更新日期：2010-06-01 00:00:00

abstract：:In 1974 we started a follow-up of patients with different psychoactive substance use disorders (PSUD) according to DSM-III; 2082 cases out of 2127 were analyzed; 1370 patients had taken legal drugs (i.e. prescription drugs and/or over-the-counter drugs); 444 patients suffered from abuse or dependence of legal drugs al...

journal_title：Drug and alcohol dependence

authors： Poser W,Poser S,Eva-Condemarin P

更新日期：1992-04-01 00:00:00

abstract：AIMS:This study investigated the serum levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in a group of chronic ketamine abusers in comparison to healthy controls. The correlations between the serum BDNF, NGF level with the subjects' demographic, pattern of ketamine use were also examined....

journal_title：Drug and alcohol dependence

authors： Ke X,Ding Y,Xu K,He H,Zhang M,Wang D,Deng X,Zhang X,Zhou C,Liu Y,Ning Y,Fan N

更新日期：2014-09-01 00:00:00

abstract：:Peripheral and autonomic neuropathy has been evaluated, both by clinical and neurophysiological and by clinical methods, respectively, in 33 alcoholics, 20 of them cirrhotics. Nerve dysfunction was compared with liver function parameters, the Child-Pugh score, and parameters derived from ethanol consumption. Few relat...

journal_title：Drug and alcohol dependence

authors： Gonzalez-Reimers E,Alonso-Socas M,Santolaria-Fernandez F,Hernandez-Peña J,Conde-Martel A,Rodriguez-Moreno F

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:States have attempted to reduce prescription opioid abuse through strengthening the regulation of pain management clinics; however, the effect of such measures remains unclear. We quantified the impact of Texas's September 2010 "pill mill" law on opioid prescribing and utilization. METHODS:We used the IMS H...

journal_title：Drug and alcohol dependence

authors： Lyapustina T,Rutkow L,Chang HY,Daubresse M,Ramji AF,Faul M,Stuart EA,Alexander GC

更新日期：2016-02-01 00:00:00

abstract：:Recently, incarcerated individuals are at increased risk of opioid overdose. Methadone maintenance treatment (MMT) is an effective way to address opioid use disorder and prevent overdose; however, few jails and prisons in the United States initiate or continue people who are incarcerated on MMT. In the current study, ...

journal_title：Drug and alcohol dependence

authors： Brinkley-Rubinstein L,McKenzie M,Macmadu A,Larney S,Zaller N,Dauria E,Rich J

更新日期：2018-03-01 00:00:00

abstract：:The current study explored the judgments individuals with Substance Use Disorders (SUDs) make regarding the authenticity of enjoyment smiles and masking smiles containing traces of negative emotions. Accuracy at identifying the masked negative emotions were also examined. Eye-movements were recorded to observe relatio...

journal_title：Drug and alcohol dependence

authors： Pelot A,Perron M,Lewis S,Roy-Charland A

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Benzodiazepine overdose rates have increased in the US, largely from concomitant use of other drugs such as opioids. Studies are needed to examine trends in prescription tranquilizer (e.g., benzodiazepine) use-with a particular focus on use of other drugs such as opioids-to continue to inform prevention effo...

journal_title：Drug and alcohol dependence

authors： Palamar JJ,Han BH,Martins SS

更新日期：2019-02-01 00:00:00