Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions.

abstract：:NiFe nanoparticles-decorated & N-doped graphene is introduced as an effective and stable non-precious electrocatalyst for ORR in the acid medium. Compared to conventional Pt/C electrodes under the same conditions, the proposed nanocatalyst shows closer onset potential and current density. Typically, the observed onset...

journal_title：Scientific reports

authors： Barakat NAM,El-Deen AG,Ghouri ZK,Al-Meer S

更新日期：2018-02-28 00:00:00

abstract：:Subsea hypersaline anoxic brine pools are among the most extreme habitable environments on Earth that offer clues to life on other planets. Brine is toxic to macrofauna as remotely operated vehicles commonly observe dead and preserved remains in brine pools. While brine pools are often assumed to be stable stratified ...

journal_title：Scientific reports

authors： Sawyer DE,Mason RA,Cook AE,Portnov A

更新日期：2019-01-15 00:00:00

abstract：:Increasing evidence has confirmed that immunoglobulins (Igs) can be expressed in non-B cells. Our previous work demonstrated that mesangial cells and podocytes express IgA and IgG, respectively. The aim of this work was to reveal whether proximal tubular epithelial cells (PTECs) express Igs. High-throughput single-cel...

journal_title：Scientific reports

authors： Deng Z,Wang X,Liu Y,Tian X,Deng S,Sun Y,Wang S,Zheng D,Cui Z,Pan Y,A L,Yan H,Qiu X,Wang Y

更新日期：2020-11-12 00:00:00

abstract：:Electrochemical biosensors have been studied intensively for several decades. Numerous sensing concepts and related interface architectures have been developed. However, all such architectures suffer a trade-off: simple architectures favour usability, whereas complex architectures favour better performance. To overcom...

journal_title：Scientific reports

authors： Zhu X,Feng C,Ye Z,Chen Y,Li G

更新日期：2014-02-25 00:00:00

abstract：:The brain-derived neurotrophic factor BDNF plays a critical role in neuronal development and the induction of L-LTP at glutamatergic synapses in several brain regions. However, the cellular and molecular mechanisms underlying these BDNF effects have not been firmly established. Using in vitro cultures of cortical neur...

journal_title：Scientific reports

authors： Ammar MR,Thahouly T,Hanauer A,Stegner D,Nieswandt B,Vitale N

更新日期：2015-10-06 00:00:00

abstract：:The effects of ocean acidification (OA) on the early recruitment of pteropods in the Scotia Sea, was investigated considering the process of spawning, quality of the spawned eggs and their capacity to develop. Maternal OA stress was induced on female pteropods (Limacina helicina antarctica) through exposure to present...

journal_title：Scientific reports

authors： Manno C,Peck VL,Tarling GA

更新日期：2016-05-16 00:00:00

abstract：:Macular edema due to neovascular age-related macular degeneration, diabetes or retinal vein occlusion can cause central vision loss. Intravitreal treatment with antibody-based biopharmaceutical compounds designed to neutralize vascular endothelial growth factor (VEGF) has proven to be an efficient strategy to ameliora...

journal_title：Scientific reports

authors： Sivertsen MS,Jørstad ØK,Grevys A,Foss S,Moe MC,Andersen JT

更新日期：2018-02-01 00:00:00

abstract：:The objective of our study is to highlight the therapeutic effect and mechanism of action by which purified Flaxseed hydrolysate (PFH) which is a lignan rich fraction exerts its anticancer activity on a human breast cancer cell line (T47D) and in mice bearing tumor. HPLC analysis of PFH of six flaxseed cultivars had s...

journal_title：Scientific reports

authors： Ezzat SM,Shouman SA,Elkhoely A,Attia YM,Elsesy MS,El Senousy AS,Choucry MA,El Gayed SH,El Sayed AA,Sattar EA,El Tanbouly N

更新日期：2018-01-11 00:00:00

abstract：:Pregnane X receptor (PXR) regulates glucose and lipid metabolism, but little is known of the nutritional regulation of PXR function. We investigated the genome wide effects of the nutritional status on the PXR mediated gene regulation in the liver. Mice were treated with a PXR ligand pregnenolone 16α-carbonitrile (PCN...

journal_title：Scientific reports

authors： Hassani-Nezhad-Gashti F,Kummu O,Karpale M,Rysä J,Hakkola J

更新日期：2019-11-13 00:00:00

abstract：:A fluorimetric Hg2+ test strip has been developed using a lotus-inspired fabrication method for suppressing the "coffee stains" toward the uniform distribution of probe materials through creating a hydrophobic drying pattern for fast solvent evaporation. The test strips were first loaded with the model probes of fluor...

journal_title：Scientific reports

authors： Qiao Y,Shang J,Li S,Feng L,Jiang Y,Duan Z,Lv X,Zhang C,Yao T,Dong Z,Zhang Y,Wang H

更新日期：2016-11-04 00:00:00

abstract：:Unexpected reactor accidents and radioisotope production and consumption have led to a continuous increase in the global-scale contamination of radionuclides. In particular, anthropogenic radioiodine has become critical due to its highly volatile mobilization and recycling in global environments, resulting in widespre...

journal_title：Scientific reports

authors： Lee SY,Lee JY,Min JH,Kim SS,Baik MH,Chung SY,Lee M,Lee Y

更新日期：2016-06-17 00:00:00

abstract：:Dietary gluten causes severe disorders like celiac disease in gluten-intolerant humans. However, currently understanding of its impact in tolerant individuals is limited. Our objective was to test whether gliadin, one of the detrimental parts of gluten, would impact the metabolic effects of an obesogenic diet. Mice we...

journal_title：Scientific reports

authors： Zhang L,Andersen D,Roager HM,Bahl MI,Hansen CH,Danneskiold-Samsøe NB,Kristiansen K,Radulescu ID,Sina C,Frandsen HL,Hansen AK,Brix S,Hellgren LI,Licht TR

更新日期：2017-03-16 00:00:00

abstract：:Early fruit development is crucial for crop production in tomato. After fertilization, the ovary undergoes cell division and cell expansion before maturation. Although the roles of regulatory signals such as hormone and carbohydrate during early fruit development have been studied, the spatial distribution and the seq...

journal_title：Scientific reports

authors： Zhang S,Xu M,Qiu Z,Wang K,Du Y,Gu L,Cui X

更新日期：2016-03-18 00:00:00

abstract：:This study sought to clarify the effects of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in angiogenesis and neurological functional recovery after cerebral ischaemic stroke in mice. In vivo, we performed behavioural tests to determine functional recovery after stroke. Double immunofluorescence staining of CD31 and...

journal_title：Scientific reports

authors： Wang D,Liu Y,Chen L,Li P,Qu Y,Zhu Y,Zhu Y

更新日期：2017-04-24 00:00:00

abstract：:The prevalence of a macrophage phenotype in atherosclerotic plaque may drive its progression and/or instability. Macrophages from coronary plaques are not available, and monocyte-derived macrophages (MDMs) are usually considered as a surrogate. We compared the MDM profile obtained from coronary artery disease (CAD) pa...

journal_title：Scientific reports

authors： Eligini S,Cosentino N,Fiorelli S,Fabbiocchi F,Niccoli G,Refaat H,Camera M,Calligaris G,De Martini S,Bonomi A,Veglia F,Fracassi F,Crea F,Marenzi G,Tremoli E

更新日期：2019-06-18 00:00:00

abstract：:Applying a circular economy approach, this research explores the use of cheese whey permeate (CWP), by-product of whey ultrafiltration, as cheap substrate for the production of bacterial cellulose (BC) and Sakacin-A, to be used in an antimicrobial packaging material. BC from the acetic acid bacterium Komagataeibacter ...

journal_title：Scientific reports

authors： Rollini M,Musatti A,Cavicchioli D,Bussini D,Farris S,Rovera C,Romano D,De Benedetti S,Barbiroli A

更新日期：2020-12-07 00:00:00

abstract：:The networks of predator-prey interactions in ecological systems are remarkably complex, but nevertheless surprisingly stable in terms of long term persistence of the system as a whole. In order to understand the mechanism driving the complexity and stability of such food webs, we developed an eco-evolutionary model i...

journal_title：Scientific reports

authors： Allhoff KT,Ritterskamp D,Rall BC,Drossel B,Guill C

更新日期：2015-06-04 00:00:00

abstract：:APOBEC3 family members are cytidine deaminases with roles in intrinsic responses to infection by retroviruses and retrotransposons, and in the control of other DNA viruses, such as herpesviruses, parvoviruses and hepatitis B virus. Although effects of APOBEC3 members on viral DNA have been demonstrated, it is not know...

journal_title：Scientific reports

authors： Milewska A,Kindler E,Vkovski P,Zeglen S,Ochman M,Thiel V,Rajfur Z,Pyrc K

更新日期：2018-04-13 00:00:00

abstract：:Fundamental life history processes of mycorrhizal fungi with inconspicuous fruiting bodies can be difficult to elucidate. In this study we investigated the species identities and life history of the orchid mycorrhizal Tulasnella fungi, which associate with the south eastern Australia orchid genus Chiloglottis. Tulasne...

journal_title：Scientific reports

authors： Ruibal MP,Triponez Y,Smith LM,Peakall R,Linde CC

更新日期：2017-07-17 00:00:00

abstract：:For the first time, high-surface-area (approximately 1465 m(2) g(-1)), highly porous and heteroatom-enriched activated carbon (HAC) was prepared from banana stems (Musa paradisiaca, Family: Musaceae) at different carbonization temperatures of 700, 800 and 900 °C (HAC) using a simple and eco-friendly method. The amount...

journal_title：Scientific reports

authors： Madhu R,Veeramani V,Chen SM

更新日期：2014-04-23 00:00:00

abstract：:The present work aimed to find out the effect of different levels of hydrolysable tannin (HT) on serum hormonal profile, biochemical indices, lipid profile, apparent digestibility of nutrients and body weight gain in healthy female rats. Forty five adult healthy female rats of 8 weeks old were randomly divided into fi...

journal_title：Scientific reports

authors： Manzoor F,Nisa MU,Hussain HA,Ahmad N,Umbreen H

更新日期：2020-11-26 00:00:00

abstract：:We compared coincidence-anticipation performance in normal vision and stroboscopic vision as a function of time-on-task. Participants estimated the arrival time of a real object that moved with constant acceleration (-0.7, 0, +0.7 m/s2) in a pseudo-randomised order across 4 blocks of 30 trials in both vision condition...

journal_title：Scientific reports

authors： Ballester R,Huertas F,Uji M,Bennett SJ

更新日期：2017-12-20 00:00:00

abstract：:The FDA-approved prophylactic antimalarial drug atovaquone (ATO) recently was repurposed as an antitumor drug. Studies show that ATO exerts a profound antiproliferative effect in several cancer cells, including breast, ovarian, and glioma. Analogous to the mechanism of action proposed in parasites, ATO inhibits mitoch...

journal_title：Scientific reports

authors： Cheng G,Hardy M,Topchyan P,Zander R,Volberding P,Cui W,Kalyanaraman B

更新日期：2020-10-21 00:00:00

abstract：:Aquaporins (AQPs) are a ubiquitous family of transmembrane water channel proteins. A subgroup of AQP water channels also facilitates transmembrane diffusion of small, polar solutes. A constriction within the pore, the aromatic/arginine (ar/R) selectivity filter, is thought to control solute permeability: previous stud...

journal_title：Scientific reports

authors： Kitchen P,Salman MM,Pickel SU,Jennings J,Törnroth-Horsefield S,Conner MT,Bill RM,Conner AC

更新日期：2019-12-30 00:00:00

abstract：:Bisphenol A (BPA), a member of the environmental endocrine disruptors (EDCs), has recently received increased attention because of its effects on brain insulin resistance. Available data have indicated that brain insulin resistance may contribute to neurodegenerative diseases. However, the associated mechanisms that u...

journal_title：Scientific reports

authors： Wang T,Xie C,Yu P,Fang F,Zhu J,Cheng J,Gu A,Wang J,Xiao H

更新日期：2017-08-08 00:00:00

abstract：:miRNAs play an indispensable role in human carcinogenesis. Dysregulated miR-1180-3p has been observed in several types of cancer, including hepatocellular carcinoma (HCC). This study intends to correlate the expression level of miR-1180-3p with clinical features and overall survival in HCC patients. The expression and...

journal_title：Scientific reports

authors： Zhou Z,Zhou X,Jiang Y,Qiu M,Liang X,Lin Q,Guo Q,Nong C,Huo R,Chen Q,Liu H,Liu Y,Zhu S,Wang M,Yu H

更新日期：2020-07-14 00:00:00

abstract：:Virtual-hand-illusion studies often use explicit and implicit measures of body ownership but no agreed-on implicit measure of agency exists. We investigated whether the Intentional Binding (IB) effect could serve as such a measure. A pilot study confirmed that current consistency increases both perceived agency and IB...

journal_title：Scientific reports

authors： Ma K,Hommel B,Chen H

更新日期：2019-03-07 00:00:00

abstract：:We study localized photonic excitations in a quasi-two-dimensional non-ideal binary microcavity lattice with use of the virtual crystal approximation. The effect of point defects (vacancies) on the excitation spectrum is investigated by numerical modelling. We obtain the dispersion and the energy gap of the electromag...

journal_title：Scientific reports

authors： Rumyantsev V,Fedorov S,Gumennyk K,Sychanova M,Kavokin A

更新日期：2014-11-06 00:00:00

abstract：:Paclitaxel (PTX) has been recognized as a promising drug for intervention of vascular reconstructions. However, it is still difficult to achieve local drug delivery in a spatio-temporally controllable manner under real-time image guidance. Here, we introduce an ultrasound (US) triggered image-guided drug delivery appr...

journal_title：Scientific reports

authors： Zhu X,Guo J,He C,Geng H,Yu G,Li J,Zheng H,Ji X,Yan F

更新日期：2016-02-22 00:00:00

abstract：:Ensuring lumpfish health and welfare in salmon farms is vital to reduce the high mortality rates reported and to guarantee a high delousing efficiency. Recent observations of farmed lumpfish livers have shown colours ranging from pale (colours 1 and 2), through bright orange (colours 3 and 4), to dark reddish-brown (c...

journal_title：Scientific reports

authors： Eliasen K,Patursson EJ,McAdam BJ,Pino E,Morro B,Betancor M,Baily J,Rey S

更新日期：2020-06-02 00:00:00