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Antimicrobial cerium ion-chitosan crosslinked alginate biopolymer films: A novel and potential wound dressing.

Abstract：

:Wound dressings require good antiseptic properties, mechanical strength and, more trustably, natural material ingredients. Antimicrobial properties of cerium ions and chitosan are known and alginate based wound dressings are commercially available. In this study, the advantages of these materials were combined and alginate films were crosslinked with cerium(III) solution and chitosan added cerium(III) solution. Films were characterized by Fourier transform infrared spectroscopy (FTIR), light transmittance, scanning electron microscopy (SEM), swelling experiments, water vapor transmittance tests, and mechanical stretching tests. The antibacterial and physical properties of the films were compared with those of conventional calcium alginate films. Both cerium ion crosslinked and cerium ion-chitosan crosslinked alginate films gained antibacterial activity against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria. Cerium alginate-chitosan films showed high resistance to being deformed elastically. Results show that cerium alginate-chitosan films can be flexible, ultraviolet-protecting, and antibacterial wound dressings.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Kaygusuz H,Torlak E,Akın-Evingür G,Özen İ,von Klitzing R,Erim FB

doi

10.1016/j.ijbiomac.2017.07.144

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

1161-1165

issue

Pt 1

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(17)31007-3

journal_volume

105

pub_type

杂志文章

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