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Viscosity of alpha-crystallin solutions.

Abstract：

:Accommodation in the mammalian lens requires flexure of lens fibres and some redistribution of their contents involving limited viscous flow. Shear-dependent viscosity of bovine alpha-crystallin solutions was determined with the Contraves Low-Shear Rheometer between 4.4 and 347 mg ml(-1), and at 15.5, 25, 30, and 37 degrees C. All solutions showed significant shear thinning, with markedly higher viscosity at physiological levels of approximately 300 mg ml(-1). Viscosity-concentration graphs were similar at low (1.0 s(-1)) and high (94.5 s(-1)) shear rates, indicating low molecular interaction in solution. Arrhenius plots which might have indicated the size of the energy barrier to displacement of molecules or aggregates were inconclusive.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Tiffany JM,Koretz JF

doi

10.1016/s0141-8130(02)00018-1

keywords:

subject

Has Abstract

pub_date

2002-06-18 00:00:00

pages

179-85

issue

3-4

eissn

0141-8130

issn

1879-0003

pii

S0141813002000181

journal_volume

30

pub_type

杂志文章

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