Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE-/- mice fed a high-fat diet.

abstract：:Relatively low serum lipid levels are thought to be an important factor contributing to the low incidence of ischemic heart diseases (IHD) in Japanese. It has been proven that obesity or overweight constitutes a basal condition for several risk factors in atherosclerosis. The purpose of this study is to obtain data on...

journal_title：Atherosclerosis

authors： Yamamoto A,Horibe H,Mabuchi H,Kita T,Matsuzawa Y,Saito Y,Nakaya N,Fujioka T,Tenba H,Kawaguchi A,Nakamura H,Goto Y

更新日期：1999-03-01 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) migration and proliferation are critical events in the development of neointima following vascular injury. In this study, we found that CD9 is constitutively expressed in the VSMC of the neointima of injured carotid arteries. The in vitro migration and proliferation of human coronary...

journal_title：Atherosclerosis

authors： Kotha J,Zhang C,Longhurst CM,Lu Y,Jacobs J,Cheng Y,Jennings LK

更新日期：2009-04-01 00:00:00

abstract：:Quantitative assessment of atherosclerosis during its natural history and following therapeutic interventions is important, as cardiovascular disease remains the most significant cause of morbidity and mortality in industrial societies. While coronary angiography delineates the vessel lumen, permitting only the indire...

journal_title：Atherosclerosis

authors： von Birgelen C,Slager CJ,Di Mario C,de Feyter PJ,Serruys PW

更新日期：1995-12-01 00:00:00

abstract：:The metabolism of homocysteine requires contributions of several enzymes and vitamin cofactors. Earlier studies identified a common polymorphism of methylenetetrahydrofolate reductase that was associated with mild hyperhomocysteinemia. Common variants of two other enzymes involved in homocysteine metabolism, methionin...

journal_title：Atherosclerosis

authors： Jacques PF,Bostom AG,Selhub J,Rich S,Ellison RC,Eckfeldt JH,Gravel RA,Rozen R,National Heart, Lung and Blood Institute, National Institutes of Health.

更新日期：2003-01-01 00:00:00

abstract：:Epidemiological evidence supports the use of non-high-density lipoprotein cholesterol (non-HDL-C), apolipoprotein B-100 (apoB), and low-density lipoprotein particles as markers of atherogenic risk. Treatment guidelines also identify these as additional targets of lipid-modifying intervention in patients with elevated ...

journal_title：Atherosclerosis

authors： Rosenson RS

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:This study examined whether combined ultrasound assessment of plaque size and echolucency in the carotid artery had an additive effect for predicting coronary events in patients with coronary artery disease (CAD). Ultrasound assessment of either plaque size or echolucency of carotid artery provides prognosti...

journal_title：Atherosclerosis

authors： Hirano M,Nakamura T,Kitta Y,Sano K,Kodama Y,Kobayashi T,Fujioka D,Saito Y,Yano T,Watanabe K,Watanabe Y,Kawabata K,Obata JE,Kugiyama K

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Serum γ-glutamyl transferase (GGT) levels are known to be positively associated with obesity. We aimed at verifying an association between baseline GGT levels and the development of obesity in Korean men. PATIENTS AND METHODS:This prospective cohort study was performed on 18,510 initially non-...

journal_title：Atherosclerosis

authors： Suh YJ,Park SK,Choi JM,Ryoo JH

更新日期：2013-04-01 00:00:00

abstract：:LDL and HDL became more fluid when health, free-living, premenopausal women were fed reduced fat diets with higher proportions of polyunsaturated fatty acids. Lipoproteins were isolated from plasma of 31 female subjects fed one of two sets of diets from typical U.S.A. foods with P/S ratios of 0.3 or 1.0. All subjects ...

journal_title：Atherosclerosis

authors： Berlin E,Judd JT,Nair PP,Jones DY,Taylor PR

更新日期：1991-02-01 00:00:00

abstract：:Atherosclerosis is considered a chronic inflammatory disease of the arterial wall. Recently, compelling evidence has arisen for the role of monocytes and neutrophils and a particular protein complex that resides within these cells - the NLRP3 inflammasome - in atherosclerosis-associated inflammation. It is now also kn...

journal_title：Atherosclerosis

authors： Martínez GJ,Celermajer DS,Patel S

更新日期：2018-02-01 00:00:00

abstract：AIMS:This study was set up to compare the accuracy, sensitivity and specificity of gene expression results between the Illumina HumanHT-12 v3 Expression BeadChip (GWE) and the TaqMan qRT-PCR low-density array (LDA) in atherosclerotic plaques. METHODS:Gene expression levels of 196 genes were determined from 22 atherosc...

journal_title：Atherosclerosis

authors： Raitoharju E,Seppälä I,Lyytikäinen LP,Levula M,Oksala N,Klopp N,Illig T,Laaksonen R,Kähönen M,Lehtimäki T

更新日期：2013-01-01 00:00:00

abstract：:The haptoglobin genotype has been demonstrated to be an independent risk factor for CVD in multiple epidemiological studies. The primary function of haptoglobin is to mitigate the deleterious effects of extracorpuscular hemoglobin. We sought to determine if the protein products of the two haptoglobin alleles differed ...

journal_title：Atherosclerosis

authors： Guetta J,Strauss M,Levy NS,Fahoum L,Levy AP

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Increasing studies have suggested that albuminuria might be an important risk factor for peripheral artery disease (PAD). However, studies focusing on the association between low-grade albuminuria and PAD are limited. It would be of great interest to elucidate the association between low-grade albuminuria an...

journal_title：Atherosclerosis

authors： Xu B,Dai M,Li M,Sun K,Zhang J,Wang T,Sun J,Chen Y,Xu M,Lu J,Bi Y

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to identify which factors influence limb salvage after bone marrow mononuclear cell implantation (BMI) in patients with chronic critical limb ischemia (CLI). METHODS:Thirteen no-option CLI patients treated with BMI were enrolled in the present study. Limb ischemia was assessed using ...

journal_title：Atherosclerosis

authors： Iso Y,Soda T,Sato T,Sato R,Kusuyama T,Omori Y,Shoji M,Koba S,Katagiri T,Kobayashi Y,Suzuki H

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Epidemiological, biological and clinical links between periodontal and cardiovascular diseases are now well established. Several human studies have detected bacterial DNA corresponding to periodontal pathogens in cardiovascular samples. Intraplaque hemorrhage has been associated with a higher risk of atherosc...

journal_title：Atherosclerosis

authors： Rangé H,Labreuche J,Louedec L,Rondeau P,Planesse C,Sebbag U,Bourdon E,Michel JB,Bouchard P,Meilhac O

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The goal of the study was to examine possible sex-related differences in the clinical characteristics and risk factors in Japanese patients with peripheral arterial disease (PAD). METHODS:Sex-related differences in clinical profiles, risk factors and treatments were examined in 730 consecutive patients with ...

journal_title：Atherosclerosis

authors： Kumakura H,Kanai H,Araki Y,Kasama S,Sumino H,Ito T,Iwasaki T,Takayama Y,Ichikawa S,Fujita K,Nakashima K,Minami K

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Adherence to a Mediterranean-style diet (MeDi) may protect against clinical vascular events by reducing atherosclerosis, but data is limited. This is the first observational study of the association between MeDi adherence and carotid plaque thickness and area. METHODS:The study included 1374 participants of ...

journal_title：Atherosclerosis

authors： Gardener H,Wright CB,Cabral D,Scarmeas N,Gu Y,Cheung K,Elkind MS,Sacco RL,Rundek T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Carbohydrates and fat intake have both been linked to development of atherosclerosis. We examined associations between glycemic index (GI) and fat intake with carotid atherosclerosis. METHODS:The Atherosclerosis Risk in Communities (ARIC) cohort enrolled participants during the period 1987-1989 and...

journal_title：Atherosclerosis

authors： Dearborn JL,Qiao Y,Guallar E,Steffen LM,Gottesman RF,Zhang Y,Wasserman BA

更新日期：2016-08-01 00:00:00

abstract：:No evidence of premature vascular disease is found in apolipoprotein A-I(Milano) (apoA-I(M)) human carriers, despite very low high density lipoprotein (HDL) cholesterol levels. Whether apoA-I(M) may impart a "gain of function" in atherosclerosis protection compared to wild-type apoA-I is hotly debated. To address this...

journal_title：Atherosclerosis

authors： Parolini C,Chiesa G,Gong E,Caligari S,Cortese MM,Koga T,Forte TM,Rubin EM

更新日期：2005-12-01 00:00:00

abstract：:In vitro incubations of human low density lipoproteins (LDL), high density lipoproteins (HDL) and lipoprotein-free plasma at 37 degrees for 6 h revealed no significant net mass transfers of esterified cholesterol from either lipoprotein fraction to the other. Observed transfers of esterified [3H]cholesterol from LDL t...

journal_title：Atherosclerosis

authors： Barter PJ,Jones ME

更新日期：1979-09-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) is known to be a secretory product of activated macrophages. TNF-alpha activates endothelial cells, stimulates angiogenesis and induces proliferation of smooth muscle cells (SMCs). Therefore, TNF-alpha has been suggested to be actively involved in the inflammatory events associa...

journal_title：Atherosclerosis

authors： Lei X,Buja LM

更新日期：1996-08-23 00:00:00

abstract：:Mast cells (MCs) contribute to atherogenesis by releasing pro-inflammatory mediators to activate vascular cells and other inflammatory cells. This study examined whether MC activation or stabilization affects diet-induced atherosclerosis in low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice. When Ldlr(-/-) mi...

journal_title：Atherosclerosis

authors： Wang J,Sjöberg S,Tia V,Secco B,Chen H,Yang M,Sukhova GK,Shi GP

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND/AIM:In type 2 diabetes and other insulin-resistant conditions, postprandial hypertriglyceridaemia is an important metabolic perturbation. To further elucidate alterations in the clearance of triglyceride-rich lipoproteins in type 2 diabetes we focused on the nutritional regulation of adipose tissue lipoprote...

journal_title：Atherosclerosis

authors： Eriksson JW,Burén J,Svensson M,Olivecrona T,Olivecrona G

更新日期：2003-02-01 00:00:00

abstract：AIMS:To examine the association between white blood cell count (WBC) and metabolic syndrome (MS) in an older Chinese population. METHODS:Three thousand and twenty men and 7,256 women aged 50-85 years were recruited and received a medical check-up including measurement of complete blood count, blood pressure, obesity i...

journal_title：Atherosclerosis

authors： Lao XQ,Neil Thomas G,Jiang C,Zhang W,Adab P,Lam TH,Cheng KK

更新日期：2008-12-01 00:00:00

abstract：:In animal model studies, the uptake of chylomicron remnants after entering in the space of Disse occurs mainly by low-density lipoprotein (LDL) receptor and LDL receptor-related protein (LRP). In subjects, the relative importance of each one of these receptors for the clearance of chylomicron remnants is not fully und...

journal_title：Atherosclerosis

authors： Sposito AC,Santos RD,Hueb W,Ventura LI,Vinagre CC,Ramires JA,Maranhão RC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is recognized that arteries can enlarge to compensate atherosclerosis. The role of diameter enlargement of unaffected arteries is not well known. We hypothesized that brachial and common carotid arteries diameters were larger in subjects with carotid atherosclerosis compared to subjects withou...

journal_title：Atherosclerosis

authors： Montalcini T,Gorgone G,Gazzaruso C,Sesti G,Perticone F,Pujia A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Recent failures of clinical trials promoting HDL-elevating therapies have prompted research groups to focus on its functional activity in disease. Endothelial effects of HDL can be measured with in vitro cell assays. The reproducibility and biological relevance of these assays have not been explored both in ...

journal_title：Atherosclerosis

authors： O'Neill F,McLoughlin E,Riwanto M,Manz J,Adler A,Sutill E,Khan T,Haywood R,Kay CW,D'Aiuto F,Charakida M,Landmesser U,Deanfield J

更新日期：2015-08-01 00:00:00

abstract：:Chronic renal failure markedly accelerates atherogenesis in apolipoprotein E-deficient (apoE(-/-)) mice. To study the putative role of receptor for advanced glycation end products (RAGE) in development of uremic atherosclerosis, apoE(-/-) mice received intraperitoneal injections thrice weekly of a neutralizing murine ...

journal_title：Atherosclerosis

authors： Bro S,Flyvbjerg A,Binder CJ,Bang CA,Denner L,Olgaard K,Nielsen LB

更新日期：2008-12-01 00:00:00

abstract：:The relations between triglyceride-rich lipoproteins, alimentary lipaemia and coronary heart disease (CHD) have remained obscure and much debated. We studied the basal and postprandial plasma levels of chylomicron remnants and very low density lipoproteins (VLDL) of varying particle size in 32 male postinfarction pati...

journal_title：Atherosclerosis

authors： Karpe F,Steiner G,Uffelman K,Olivecrona T,Hamsten A

更新日期：1994-03-01 00:00:00

abstract：:Remnant lipoproteins are known to promote atherosclerosis especially in patients with type III hyperlipoproteinemia (HLP). In the current study, the effects of atorvastatin were investigated with special reference to the exogenous and endogenous apolipoprotein (apo) B-containing lipoprotein metabolism in type III HLP....

journal_title：Atherosclerosis

authors： Ishigami M,Yamashita S,Sakai N,Hirano K,Hiraoka H,Nakamura T,Matsuzawa Y

更新日期：2003-06-01 00:00:00

abstract：:In previous works, it has been evidenced that lipoperoxidative injury to macrophages caused by oxidatively modified low-density lipoprotein (O-LDL) plays an important role in foam cell formation, and that PSK, a protein bound polysaccharide extracted from the class Basidiomycetes Coriolus Versicolor, can protect macro...

journal_title：Atherosclerosis

authors： Yuan C,Mei Z,Liu S,Yi L

更新日期：1996-08-02 00:00:00