Abstract：
OBJECTIVES:The aim of this study was to determine the prevalence of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) among healthcare workers (HCWs) compared with non-HCWs at Duhok city, Kurdistan Region, northern Iraq. METHODS:A total of 182 HCWs with different occupations and working in different hospital units as well as 198 non-HCWs were recruited. Nasal swab samples were collected and were inoculated on mannitol salt agar and incubated at 35°C for 48h. Isolates identified as S. aureus underwent antimicrobial sensitivity testing to oxacillin. MRSA isolates were selected and investigated for presence of the mecA gene. RESULTS:Among the HCWs, 41/182 (22.5%) were carriers of S. aureus compared with 37/198 (18.7%) non-HCWs (P=0.4). Amongst the S. aureus carriers, 25/41 strains (61.0%) isolated from HCWs were MRSA compared with 8/37 strains (21.6%) isolated from non-HCWs (P=0.039). The mean age of MRSA carriers was 35.6±6.7years compared with 30±5.8years for MRSA non-carriers (P=0.0177). The mean working years of MRSA carriers was significantly higher than that of MRSA non-carriers (7.8±5.5years vs. 3.9±5.3years; P=0.04). CONCLUSIONS:The prevalence of MRSA was very high amongst HCWs. Regular screening of carriers is required for prevention of nosocomial infections.
journal_name
J Glob Antimicrob Resistjournal_title
Journal of global antimicrobial resistanceauthors
Hussein NR,Assafi MS,Ijaz Tdoi
10.1016/j.jgar.2017.01.010subject
Has Abstractpub_date
2017-06-01 00:00:00pages
78-81eissn
2213-7165issn
2213-7173pii
S2213-7165(17)30046-2journal_volume
9pub_type
杂志文章abstract：OBJECTIVES:This study aimed to characterise insertional mutations disturbing themgrB gene in carbapenem-resistant Klebsiella pneumoniae (CRKp). METHODS:A total of 118 clinical CRKp isolates were surveyed for polymyxin resistance and insertion sequence (IS) elements disruptingmgrB. RESULTS:Of the 118 isolates, 78 (66....
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.11.003
更新日期：2020-11-24 00:00:00
abstract：OBJECTIVES:Rates of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) have increased. A meta-analysis was conducted to explore risk factors for CRKP infection in order to provide a theoretical basis for reducing the CRKP infection rate and actively preventing CRKP infection. METHODS:Onl...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2019.09.006
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVES:Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. METHODS:In vitro testing was performed by the lactate dehydrogenase assay in chloroquine (CQ)-sensitive Plasmodium falci...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.07.027
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to determine the percentage of antimicrobial-resistant isolates and the associated resistance mechanisms in Gram-negative bacteria from South Western Nigeria. METHODS:A total of 306 non-duplicate unbiased Gram-negative isolates were recovered from patients admitted to three teachin...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2019.10.016
更新日期：2020-06-01 00:00:00
abstract：:According to the World Health Organization (WHO), as of today, there are 2.165.500 confirmed cases of the novel coronavirus disease (COVID-19) and 145.705 deaths in over 185 countries. Unfortunately, despite the tremendous efforts to develop a vaccine initiated by various leading health institutions all over the world...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.07.005
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:Urinary tract infections (UTIs) are one of the most common infections in humans. Studies have shown that antibiotics for UTIs are usually prescribed empirically before the results of urine culture are available. The aim of the study was to assess the antimicrobial resistance patterns of bacteria isolated fro...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2019.01.022
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:Thousands of cases of multidrug-resistant tuberculosis (TB) have been observed in the Philippines, but studies on the Mycobacterium tuberculosis (MTB) genotypes that underlie the observed drug resistance profiles are lacking. This study aimed to analyse the whole genomes of clinical MTB isolates representing...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2018.08.009
更新日期：2018-12-01 00:00:00
abstract：:Environmental fungicides are used in agriculture to reduce fungal spoilage of crops to a minimum, and the polyene macrolide natamycin is used as a food preservative. The use of natamycin in yoghurt has recently been authorised in the USA and some other countries. However, resistance development is a serious risk assoc...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章,评审
doi：10.1016/j.jgar.2017.10.024
更新日期：2018-06-01 00:00:00
abstract：:Coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses increase oxidative stress in the body leading to cellular and tissue damage. To combat this, administration of high-dose vitamin C (ascorbic acid or ascorbate), in addition to standard conventional supportive treat...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章,评审
doi：10.1016/j.jgar.2020.09.025
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND AND AIM:The global rise of antimicrobial resistance among bacterial strains is a rapidly growing challenge and is becoming a major public health concern. This study documents the worldwide spread and genotype distribution of human clinical isolates of New Delhi metallo-β-lactamase-producing Klebsiella pneumo...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章,评审
doi：10.1016/j.jgar.2020.10.016
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:Escherichia coli and Enterobacter cloacae are two major pathogens causing urinary tract infection (UTI). Here we characterised the genome of an NDM-1-producing E. cloacae strain and an extended-spectrum β-lactamase (ESBL)-producing E. coli strain that were co-isolated from a UTI. METHODS:The genomes of E. c...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2019.04.007
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVES:Mortality associated with carbapenemase-producing Enterobacteriaceae is high as there are few therapeutic options. Escherichia coli sequence type 410 (ST410) is currently an international high-risk clone and is responsible for a large number of clinical infections. Here we report the draft genome sequence of...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2019.10.027
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVES:Recently, a growing resistance to antimalarial drugs such as chloroquine, sulfadoxine-pyrimethamine, artemisinin derivatives and mefloquine has been observed. The pharmacokinetic limitation of the current therapy and multi-drug resistance has resulted in an urgent need to study the new antimalarial combinati...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.02.018
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:Multidrug-resistant (MDR) Enterobacter aerogenes strains are frequently associated with nosocomial infections and high mortality rates, representing a serious public health problem. The aim of this study was to present the draft genome sequence of a MDR KPC-2-producing E. aerogenes isolated from a perineal s...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2017.07.016
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:This meta-analysis was performed to compare polymyxin monotherapy and polymyxin-based combination therapy for carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections. METHODS:We conducted searches on MEDLINE, Embase and Cochrane Collaborative database for both observational studies and randomised cont...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.08.024
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:Staphylococcus aureus remains the most important cause of infections in hospitals and long-term care facilities. The aim of this study was to analyse the resistance, virulence, and epidemiological and genetic relationships of S. aureus from bloodstream infections (BSIs) and pneumonia from patients in Souther...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2017.07.009
更新日期：2017-12-01 00:00:00
abstract：:Antimicrobial resistance severely limits the therapeutic options for many clinically important bacteria. In Gram-negative bacteria, multidrug resistance is commonly facilitated by plasmids that have the ability to accumulate and transfer refractory genes amongst bacterial populations. The aim of this study was to isol...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2016.01.011
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVES:Recently, the virulence factor sasX was described on the mobile genetic element φSPβ prophage in a ST239-SCCmecIII methicillin-resistant Staphylococcus aureus (MRSA) clone. The aim of this study was to identify sesI, an sasX homologue, in an MRSA ST239 strain. METHODS:MRSA strain VB1490 was isolated from a ...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2019.02.006
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:Bacillus spp., which have relevance to pseudo-epidemics in clinics, may cause serious infections as well as high morbidity and mortality in hospitalised patients with haematological malignancies. Here we report the isolation of Bacillus sp. M13(2017) with a multidrug-resistant phenotype and spore-producing s...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2018.07.002
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:Multidrug-resistant bacteria have become a serious threat worldwide. In particular, the coexistence of carbapenemase genes and mcr-1 leaves few available treatment options. Here we report a multidrug-resistant Escherichia coli isolate harbouring both mcr-1 and blaNDM-9 from a patient with a urinary tract inf...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2018.10.003
更新日期：2019-03-01 00:00:00
abstract：:Acinetobacter calcoaceticus-baumannii complex is a common cause of hospital-acquired infections (HAIs) globally, remarkable for its high rate of antibiotic resistance, including to carbapenems. There are few data on the resistance of A. baumannii in Vietnam, which are essential for developing evidence-based treatment ...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2014.05.003
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVES:This study aimed to determine the prevalence of linezolid-resistant (LR) vancomycin-resistant enterococci and to investigate the mechanisms of linezolid resistance with clinical and microbiological characterisation. METHODS:All vancomycin-resistant Enterococcus faecium (VREF) isolated from blood and rectal ...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2017.09.009
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVES:The Klebsiella pneumoniae carbapenemase (blaKPC) gene is one of the most widespread carbapenemase genes in the world. However, there are few reports on KPC-producing bacteria in Japan. The aim of this study was therefore to investigate KPC-producing K. pneumoniae in Japan. METHODS:A KPC-2-producingK. pneumo...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.12.007
更新日期：2020-12-26 00:00:00
abstract：:In the past few years, Europe has experienced an enormous influx of refugees and migrants owing to the ongoing civil war in Syria as well as conflicts, violence and instability in other Asian and African countries. Available data suggest that refugees carry a significant burden of multidrug-resistant (MDR) organisms, ...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章,评审
doi：10.1016/j.jgar.2017.03.013
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:Corynebacterium urealyticum is a non-diphtherial urease-producing clinically relevant corynebacterium associated with urinary tract infections. Most clinical C. urealyticum isolates are multidrug-resistant. Whole-genome sequencing (WGS) of C. urealyticum VH4248 isolated from a clinical urine sample at Hospit...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.07.020
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:The aims of this study were (i) to determine the frequency of plasmid-mediated resistance to fluoroquinolones (FQs) in Escherichia coli isolated from patients with urinary tract infections (UTIs) of nosocomial and community origin and (ii) to determine the relationships between the presence of extended-spect...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2017.12.013
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVES:Ralstonia pickettii has been increasingly recognised as an emerging opportunistic pathogen in hospital settings in recent years, especially in patients with prolonged hospital stay. Clinical manifestations associated with R. pickettii infection range from mild infections to severe invasive life-threatening i...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2020.02.020
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to examine the performance of the chromogenic β LACTA™ test for the rapid detection of expanded-spectrum cephalosporin (ESC) non-susceptibility among Enterobacteriaceae in a region endemic for potent β-lactamases. METHODS:The β LACTA™ test was applied prospectively on 235 consecuti...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2017.05.018
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:Acinetobacter spp. isolates carrying the blaNDM-1 gene are frequently reported. However, most reported blaNDM-1 genes are carried by clinical strains. Here we report a carbapenem-resistant Acinetobacter towneri isolate from hospital sewage in China co-harbouring blaNDM-1 and blaOXA-58 in the genome. METHODS...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2018.11.015
更新日期：2019-03-01 00:00:00
abstract：:Haemophilus influenzae is an important human pathogen usually susceptible to quinolones. Here we report the emergence of high-level ciprofloxacin-monoresistant H. influenzae in the Region of Southern Denmark. Four isolates were collected for phenotypic and molecular characterisation using whole-genome sequencing (WGS)...
journal_title：Journal of global antimicrobial resistance
pub_type： 杂志文章
doi：10.1016/j.jgar.2015.12.004
更新日期：2016-06-01 00:00:00
