The major neurotransmitter systems in the basolateral amygdala and the ventral tegmental area mediate morphine-induced memory consolidation impairment.

abstract：:Immunohistochemistry for vanilloid receptor 1-like receptor (VRL-1), a candidate transducer for high-threshold noxious heat, was performed on rat trigeminal primary sensory neurons. The immunoreactivity was detected in 14% of the trigeminal ganglion cell bodies, while the neurons in the mesencephalic trigeminal tract ...

journal_title：Neuroscience

authors： Ichikawa H,Sugimoto T

更新日期：2000-01-01 00:00:00

abstract：:Migration of postmitotic neurons in the developing cortex along radial glial fiber is essential for the formation of cortical layers. Several neurological diseases are caused by defects in neuronal migration, underlining the importance of this process for brain function. Multiple molecules are involved in this process...

journal_title：Neuroscience

authors： Wang JT,Song LZ,Li LL,Zhang W,Chai XJ,An L,Chen SL,Frotscher M,Zhao ST

更新日期：2015-04-30 00:00:00

abstract：:Resident microglia are involved in immune responses of the central nervous system and may contribute to neuronal degeneration and death. Here, we tested in adult rats whether injection of bacterial lipopolysaccharide (which causes inflammation and microglial activation) just above the substantia nigra, results in the ...

journal_title：Neuroscience

authors： Lu X,Bing G,Hagg T

更新日期：2000-01-01 00:00:00

abstract：:The inferior colliculus (IC) integrates ascending auditory input from the lower brainstem and descending input from the auditory cortex. Understanding how IC cells integrate these inputs requires identification of their synaptic arrangements. We describe excitatory synapses in the dorsal cortex, central nucleus, and l...

journal_title：Neuroscience

authors： Nakamoto KT,Mellott JG,Killius J,Storey-Workley ME,Sowick CS,Schofield BR

更新日期：2013-05-01 00:00:00

abstract：:Cultures of 11 day old chick embryo pectoral muscle were used to study the effects of direct electrical stimulation and neurochemicals such as acetylcholine, acetyl-beta-methylcholine, tetrodotoxin, and d-tubocurarine on the acetylcholinesterase levels of muscle. The results suggest that excitation-contraction is an i...

journal_title：Neuroscience

authors： Walker CR,Wilson BW

更新日期：1976-06-01 00:00:00

abstract：:The ability to generate subthreshold membrane potential oscillations in neurons from the inferior olive nucleus has been attributed to the electrical properties of these neurons, as well as to the properties of the network. In the present in vitro study we quantitatively characterized both intrinsic membrane and netwo...

journal_title：Neuroscience

authors： Lampl I,Yarom Y

更新日期：1997-05-01 00:00:00

abstract：:The role of GABA(A) receptors in the mediodorsal thalamus (mdT) in turning behaviour of rats was studied. Neither the GABA(A) receptor agonist muscimol (50 ng) nor the antagonist bicuculline (200 ng) unilaterally injected into the mdT elicited any behavioural change. Unilateral injection of the acetylcholine receptor ...

journal_title：Neuroscience

authors： Ikeda H,Kotani A,Lee J,Koshikawa N,Cools AR

更新日期：2009-04-10 00:00:00

abstract：:Several genes encoding subunits of the neuronal nicotinic acetylcholine receptors have been cloned and regulatory elements involved in the transcription of the alpha 2 and alpha 7-subunit genes have been described. Yet, the detailed mechanisms governing the neuron-specific transcription and the spatio-temporal express...

journal_title：Neuroscience

authors： Bessis A,Salmon AM,Zoli M,Le Novère N,Picciotto M,Changeux JP

更新日期：1995-12-01 00:00:00

abstract：:The human brain is composed of complex networks of 100 billion neurons that underlie its higher functions. The set of neural connections in the brain has recently attracted growing interest from the scientific community. It is important to identify individual differences in these neural connections to study the backgr...

journal_title：Neuroscience

authors： Takao H,Hayashi N,Ohtomo K

更新日期：2015-08-20 00:00:00

abstract：:Choline is essential to the development and function of the central nervous system and supplemental choline during development is neuroprotective against a variety of insults, including neurotoxins like dizocilpine (MK-801). MK-801 is an NMDA receptor antagonist that is frequently used in rodent models of psychologica...

journal_title：Neuroscience

authors： Nickerson CA,Brown AL,Yu W,Chun Y,Glenn MJ

更新日期：2017-10-11 00:00:00

abstract：:Activation of neurokinin-1 (NK-1) receptors in the rostral ventromedial medulla (RVM) can facilitate pain transmission in conditions such as inflammation, and thereby contribute to hyperalgesia. Since blockade of NK-1 receptors in the RVM can attenuate hyperalgesia produced by prolonged inflammation, we examined the r...

journal_title：Neuroscience

authors： Khasabov SG,Brink TS,Schupp M,Noack J,Simone DA

更新日期：2012-11-08 00:00:00

abstract：:How does our mind produce physical, goal-directed action of our body? For about 200years, philosophers and psychologists hypothesized the transformation from mind to body to rely on the anticipation of an action's sensory consequences. Whereas this hypothesis received tremendous support from behavioral experiments, th...

journal_title：Neuroscience

authors： Pfister R,Melcher T,Kiesel A,Dechent P,Gruber O

更新日期：2014-02-14 00:00:00

abstract：:Fathers play a substantial role in infant care in a small but significant number of mammalian species, including humans. However, the neural circuitry controlling paternal behavior is much less understood than its female counterpart. In order to characterize brain areas activated by paternal care, male California mice...

journal_title：Neuroscience

authors： de Jong TR,Measor KR,Chauke M,Harris BN,Saltzman W

更新日期：2010-09-01 00:00:00

abstract：:Several lines of evidence suggest that integrin receptors play a pivotal role in consolidation of long-term potentiation (LTP), but which of the many integrin dimers are involved remains to be discovered. The present study used an LTP reversal paradigm to test if alpha3 integrins make an important contribution. Functi...

journal_title：Neuroscience

authors： Kramár EA,Bernard JA,Gall CM,Lynch G

更新日期：2002-01-01 00:00:00

abstract：:In humans, bromocriptine (BRO) is used as a treatment for many disorders, such as prolactinomas, even during pregnancy and lactation. Previously we demonstrated that maternal BRO treatment at the end of lactation programs offspring for obesity and several endocrine dysfunctions. Here, we studied the long-term effects ...

journal_title：Neuroscience

authors： Carvalho JC,Lisboa PC,de Oliveira E,Peixoto-Silva N,Pinheiro CR,Fraga MC,Claudio-Neto S,Franci CR,Manhães AC,Moura EG

更新日期：2016-06-14 00:00:00

abstract：:To investigate whether acetylcholine is released in a similar fashion in different regions of the cortex, in vivo microdialysis was used to measure acetylcholine efflux simultaneously in the medial prefrontal and the frontoparietal cortex, under both basal conditions and following tactile stimulation. Additionally, th...

journal_title：Neuroscience

authors： Himmelheber AM,Fadel J,Sarter M,Bruno JP

更新日期：1998-10-01 00:00:00

abstract：:Multiple descending systems for pain control originate from the rostral medulla and midbrain. These systems are involved in the antinociceptive action produced by opioids. One category of descending inhibitory controls is activated specifically by noxious stimuli and has been termed diffuse noxious inhibitory controls...

journal_title：Neuroscience

authors： Bouhassira D,Chitour D,Villaneuva L,Le Bars D

更新日期：1995-12-01 00:00:00

abstract：:To determine the role of the frontal cortex in the generalization of limbic seizures, we first produced unilateral cortical spreading depression to reversibly suppress neuronal activity in the motor cortex and then triggered an amygdala-kindled seizure. Three minutes following induction of unilateral spreading depress...

journal_title：Neuroscience

authors： Kelly ME,Battye RA,McIntyre DC

更新日期：1999-01-01 00:00:00

abstract：:The cre/loxP system is used routinely to manipulate gene expression in the mouse nervous system. In order to delete genes specifically from the telencephalon, the Foxg1-cre line was created previously by replacing the intron-less Foxg1 coding region with cre, resulting in a Foxg1 heterozygous mouse. As the telencephal...

journal_title：Neuroscience

authors： Eagleson KL,Schlueter McFadyen-Ketchum LJ,Ahrens ET,Mills PH,Does MD,Nickols J,Levitt P

更新日期：2007-08-24 00:00:00

abstract：:Microelectrode recordings were made from 5-10 micron dia axons of adult rat spinal cord in vitro. Action potentials in response to electrical stimulation were recorded intracellularly and electrical characteristics of the axons were examined by injecting current pulses through a bridge circuit. All action potentials l...

journal_title：Neuroscience

authors： Blight AR,Someya S

更新日期：1985-05-01 00:00:00

abstract：:Recently, it was reported that stimulation of the infralimbic cortex produces a feedforward inhibition of central amygdala neurons. The interest of this observation comes from the fact that the central nucleus is the main output station of the amygdala for conditioned fear responses and evidence that the infralimbic c...

journal_title：Neuroscience

authors： Berretta S,Pantazopoulos H,Caldera M,Pantazopoulos P,Paré D

更新日期：2005-01-01 00:00:00

abstract：:The present studies aimed to determine whether estradiol (E(2)) modulates the stimulation of cocaine- and amphetamine-regulated transcript (CART) peptide in the mesolimbic and nigrostriatal dopaminergic systems. I.c.v. administration of the CART peptide (55-102, 1 microg/3 microl) increased dopamine turnover (3,4-dihy...

journal_title：Neuroscience

authors： Shieh KR,Yang SC

更新日期：2008-07-17 00:00:00

abstract：:Histamine, a putative neuromodulator and neurotransmitter, can depolarize supraoptic neurons and enhance depolarizing afterpotentials that play a key role in determining the excitability of these neurons. This study investigated intracellular signal transduction involved in histamine-induced enhancement of depolarizin...

journal_title：Neuroscience

authors： Li Z,Miyata S,Hatton GI

更新日期：1999-01-01 00:00:00

abstract：:In the ascending auditory pathway, the central nucleus of the inferior colliculus (IC) receives and integrates excitatory and inhibitory inputs from many bilateral lower auditory nuclei, intrinsic projections within the IC, contralateral IC through the commissure of the IC and from the auditory cortex. All these presy...

journal_title：Neuroscience

authors： Wang H,Shen S,Zheng T,Bi L,Li B,Wang X,Yang Y,Jen PH

更新日期：2018-10-15 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) produce widespread and complex effects on neocortex excitability. We studied how heteromeric nAChRs regulate inhibitory post-synaptic currents (IPSCs), in fast-spiking (FS) layer V neurons of the mouse frontal area 2 (Fr2). In the presence of blockers of ionotropic glutamate ...

journal_title：Neuroscience

authors： Aracri P,Meneghini S,Coatti A,Amadeo A,Becchetti A

更新日期：2017-01-06 00:00:00

abstract：:Iron may catalyse the production of reactive oxygen species during post-ischemic reoxygenation and subsequently lead to brain damage. Ferritin, an iron sequestering and storage protein, can also be a source of iron after ischemic insult. However, its role in ischemia-reperfusion has not been carefully investigated. In...

journal_title：Neuroscience

authors： Chi SI,Wang CK,Chen JJ,Chau LY,Lin TN

更新日期：2000-01-01 00:00:00

abstract：:The gp130 cytokines leukemia inhibitory factor and interleukin-6 are neuroactive cytokines associated with peripheral nerve injury. Here we show that exogenous administration of these factors selectively regulates neuropeptide phenotype in intact sensory neurons in a manner consistent with their role as injury-induced...

journal_title：Neuroscience

authors： Thompson SW,Priestley JV,Southall A

更新日期：1998-06-01 00:00:00

abstract：:The anatomical localization and pharmacology of alpha5 subunit-containing GABA type-A receptors in the human hippocampal formation of Alzheimer's disease patients were studied with an alpha5 receptor selective ligand, [3H]L-655,708 and compared to age-matched human controls. Autoradiographic analyses revealed a hetero...

journal_title：Neuroscience

authors： Howell O,Atack JR,Dewar D,McKernan RM,Sur C

更新日期：2000-01-01 00:00:00

abstract：:Sigma receptor (sigmaR), known as a unique nonopiate, nonphencyclidine brain receptor, can bind diverse classes of psychotropic drugs, neurosteroids and other synthetic compounds, such as (+)pentazocine, etc. Two types of sigmaRs have been identified: sigmaR1 and sigmaR2. In this work, we examined the expression of si...

journal_title：Neuroscience

authors： Liu LL,Wang L,Zhong YM,Yang XL

更新日期：2010-06-02 00:00:00

abstract：:The axonal transport of the molecular forms of acetylcholinesterase was investigated in regenerating facial nerves of guinea-pig and rat. Four forms were separated by velocity sedimentation corresponding to 16S (A12), 10S (G4), 6S (G2) and 4S (G1) acetylcholinesterase. They displayed species-specific changes, which ar...

journal_title：Neuroscience

authors： Engel AK,Tetzlaff W,Kreutzberg GW

更新日期：1988-02-01 00:00:00