KATP Channels Mediate Differential Metabolic Responses to Glucose Shortage of the Dorsomedial and Ventrolateral Oscillators in the Central Clock.

abstract：:On an SiO2-patterned c-plane sapphire substrate, GaN domains were grown with their polarity controlled in accordance with the pattern. While N-polar GaN was grown on hexagonally arranged circular openings, Ga-polar GaN was laterally overgrown on mask regions due to polarity inversion occurring at the boundary of the c...

journal_title：Scientific reports

authors： Jang D,Jue M,Kim D,Kim HS,Lee H,Kim C

更新日期：2018-03-07 00:00:00

abstract：:In the central nervous system of vertebrates, cell bodies of neurons are often assembled as nuclei or cellular layers that play specific roles as functional units. The purpose of this work was to selectively highlight such cell assemblies by magnetic resonance imaging using signals from water protons that are associat...

journal_title：Scientific reports

authors： Watanabe T,Wang X,Tan Z,Frahm J

更新日期：2019-03-25 00:00:00

abstract：:Crypt neurons are a third type of olfactory receptor neurons with a highly unusual "one cell type--one receptor" mode of expression, the same receptor being expressed by the entire population of crypt neurons. Attempts to identify the target region(s) of crypt neurons have been inconclusive so far. We report that TrkA...

journal_title：Scientific reports

authors： Ahuja G,Ivandic I,Saltürk M,Oka Y,Nadler W,Korsching SI

更新日期：2013-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is an EBV-associated epithelial malignancy prevalent in southern China. Presence of treatment-resistant cancer stem cells (CSC) may associate with tumor relapse and metastasis in NPC. ICG-001 is a specific CBP/β-catenin antagonist that can block CBP/β-catenin-mediated transcription of st...

journal_title：Scientific reports

authors： Chan KC,Chan LS,Ip JC,Lo C,Yip TT,Ngan RK,Wong RN,Lo KW,Ng WT,Lee AW,Tsao GS,Kahn M,Lung ML,Mak NK

更新日期：2015-04-21 00:00:00

abstract：:Seed germination behavior is an important factor in the distribution of species. Many studies have shown that germination is controlled by phylogenetic constraints, however, it is not clear whether phylogenetic constraints or environmental cues explain seed germination of a genus from a common ancestor. In this study,...

journal_title：Scientific reports

authors： Fang XW,Zhang JJ,Xu DH,Pang J,Gao TP,Zhang CH,Li FM,Turner NC

更新日期：2017-09-12 00:00:00

abstract：:Circadian disruption resulting from exposure to irregular light-dark patterns and sleep deprivation has been associated with beta amyloid peptide (Aβ) aggregation, which is a major event in Alzheimer's disease (AD) pathology. We exposed 5XFAD mice and littermate controls to dim-light vs. bright-light photophases to in...

journal_title：Scientific reports

authors： Nagare R,Possidente B,Lagalwar S,Figueiro MG

更新日期：2020-07-10 00:00:00

abstract：:Chronic myeloid leukemia (CML) is characterized in the majority of cases by a t(9;22)(q34;q11) translocation, also called the Philadelphia chromosome, giving rise to the BCR-ABL1 fusion protein. Current treatment with tyrosine kinase inhibitors is directed against the constitutively active ABL1 domain of the fusion pr...

journal_title：Scientific reports

authors： Löf L,Arngården L,Olsson-Strömberg U,Siart B,Jansson M,Dahlin JS,Thörn I,Christiansson L,Hermansson M,Larsson A,Ahlstrand E,Wålinder G,Söderberg O,Rosenquist R,Landegren U,Kamali-Moghaddam M

更新日期：2017-04-04 00:00:00

abstract：:Superconductivity in noncentrosymmetric compounds has attracted sustained interest in the last decades. Here we present a detailed study on the transport, thermodynamic properties and the band structure of the noncentrosymmetric superconductor La 7 Ir 3 (T c  ~ 2.3 K) that was recently proposed to break the time-rever...

journal_title：Scientific reports

authors： Li B,Xu CQ,Zhou W,Jiao WH,Sankar R,Zhang FM,Hou HH,Jiang XF,Qian B,Chen B,Bangura AF,Xu X

更新日期：2018-01-12 00:00:00

abstract：:Few studies have examined the potential transcription factor (TF) simultaneously associated with cisplatin resistance and metastasis in ovarian cancer. To assess a related mechanism, a 345-channel protein/DNA array and transcriptional activity ELISA were performed to compare the TF activities in the cisplatin-sensitiv...

journal_title：Scientific reports

authors： Sun P,Song Y,Liu D,Liu G,Mao X,Dong B,Braicu EI,Sehouli J

更新日期：2018-09-07 00:00:00

abstract：:Due to their immunosuppressive properties, mesenchymal stem cells (MSC) have been evaluated for the treatment of immunological diseases. However, the animal-derived growth supplements utilized for MSC manufacturing may lead to clinical complications. Characterization of alternative media formulations is imperative for...

journal_title：Scientific reports

authors： Oikonomopoulos A,van Deen WK,Manansala AR,Lacey PN,Tomakili TA,Ziman A,Hommes DW

更新日期：2015-11-13 00:00:00

abstract：:Guanine-rich quadruplex (G-QD) are formed by conversion of nucleotides with specific sequences by stabilization of positively charged K+ or Na+. These G-QD structures differentially absorb two-directional (right- and left-handed) circularly polarized light, which can discriminate the parallel or anti-parallel structur...

journal_title：Scientific reports

authors： Kim R,Youn YS,Kang M,Kim E

更新日期：2020-11-24 00:00:00

abstract：:Male moths efficiently recognize conspecific sex pheromones thanks to their highly accurate and specific olfactory system. The Heliothis/Helicoverpa species are regarded as good models for studying the perception of sex pheromones. In this study, we performed a series of experiments to investigate the peripheral mecha...

journal_title：Scientific reports

authors： Chang H,Guo M,Wang B,Liu Y,Dong S,Wang G

更新日期：2016-01-08 00:00:00

abstract：:Despite efforts to characterize the different aspects of musical abilities in humans, many elements of this complex area remain unknown. Musical abilities are known to be associated with factors like intelligence, training, and sex, but a comprehensive evaluation of the simultaneous impact of multiple factors has not ...

journal_title：Scientific reports

authors： Smith LM,Bartholomew AJ,Burnham LE,Tillmann B,Cirulli ET

更新日期：2017-11-28 00:00:00

abstract：:Channelrhodopsins are light-gated ion channels of green algae used for the precise temporal and spatial control of transmembrane ion fluxes. The channelrhodopsin Chrimson from Chlamydomonas noctigama allows unprecedented deep tissue penetration due to peak absorption at 590 nm. We demonstrate by electrophysiological r...

journal_title：Scientific reports

authors： Vierock J,Grimm C,Nitzan N,Hegemann P

更新日期：2017-08-30 00:00:00

abstract：:The Brazilian Urban Mobility Policy integrates urban transport with traffic planning, establishing appropriate public policies that indicate the need for a safe and accessible public transport system. The major challenge is the inclusion of the elderly and people with disabilities. In this paper, we quantify the impac...

journal_title：Scientific reports

authors： Azevedo GA,Sampaio RR,Filho ASN,Moret MA,Murari TB

更新日期：2021-01-12 00:00:00

abstract：:EndMT has an important effect on metastasis and progression of tumor. This work will elucidate the effect of miR-494 on EndMT and development of HCC. Therefore, the differential miRNA expression among non-tumorous, para-tumorous and tumorous tissues was analyzed. Moreover, luciferase activities of SIRT3 3'UTR treated ...

journal_title：Scientific reports

authors： Zhang J,Zhu Y,Hu L,Yan F,Chen J

更新日期：2019-05-10 00:00:00

abstract：:Transparent anti-fogging and self-cleaning coatings are of great interest for many applications, including solar panels, windshields and displays or lenses to be used in humid environments. In this paper, we report on the simultaneous synthesis, at atmospheric pressure, of anatase TiO2 nanoparticles and low-temperatur...

journal_title：Scientific reports

authors： Chemin JB,Bulou S,Baba K,Fontaine C,Sindzingre T,Boscher ND,Choquet P

更新日期：2018-06-25 00:00:00

abstract：:Circulating miRNAs have attracted attention as serum biomarkers for several diseases. In this study, we aimed to evaluate the diagnostic value of circulating miRNA-21 (miR-21) as a novel biomarker for elderly patients with type 2 cardiorenal syndrome (CRS-2). A total of 157 elderly patients with chronic heart failure ...

journal_title：Scientific reports

authors： Wang Y,Liang Y,Zhao W,Fu G,Li Q,Min X,Guo Y

更新日期：2020-03-17 00:00:00

abstract：:Directed transport of biological species across the surface of a substrate is essential for realizing lab-on-chip technologies. Approaches that utilize localized magnetic fields to manipulate magnetic particles carrying biological entities are attractive owing to their sensitivity, selectivity, and minimally disruptiv...

journal_title：Scientific reports

authors： Rapoport E,Beach GSD

更新日期：2017-08-31 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Yu C,Li T,Zhang R,Yang X,Yang Z,Xin L,Zhao Z

更新日期：2020-04-29 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...

journal_title：Scientific reports

authors： Duca F,Zotter-Tufaro C,Kammerlander AA,Aschauer S,Binder C,Mascherbauer J,Bonderman D

更新日期：2018-01-18 00:00:00

abstract：:The villous cytotrophoblastic cells have the ability to fuse and differentiate, forming the syncytiotrophoblast (STB). The syncytialisation process is essential for placentation. Nevertheless, the mechanisms involved in cell fusion and differentiation are yet to be fully elucidated. It has been suggested that cell sur...

journal_title：Scientific reports

authors： Bastida-Ruiz D,Wuillemin C,Pederencino A,Yaron M,Martinez de Tejada B,Pizzo SV,Cohen M

更新日期：2020-06-15 00:00:00

abstract：:Photonic integrated circuits for photonic computing open up the possibility for the realization of ultrahigh-speed and ultra wide-band signal processing with compact size and low power consumption. Differential equations model and govern fundamental physical phenomena and engineering systems in virtually any field of ...

journal_title：Scientific reports

authors： Yang T,Dong J,Lu L,Zhou L,Zheng A,Zhang X,Chen J

更新日期：2014-07-04 00:00:00

abstract：:Soil water retention curve (SWRC) plays an important role in simulating soil water movement and assessing soil water holding capacity and availability. Comparison of fitness between different models to determine the best SWRC model of specific regions is required. In this study, three popular models, van Genuchten, Br...

journal_title：Scientific reports

authors： Pan T,Hou S,Liu Y,Tan Q

更新日期：2019-12-05 00:00:00

abstract：:Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages. Here, we use a low-carbon based strategy to cultivate low-abundance bacteria from Spongia officinalis. This approach favoured the growth of Alphaproteoba...

journal_title：Scientific reports

authors： Karimi E,Keller-Costa T,Slaby BM,Cox CJ,da Rocha UN,Hentschel U,Costa R

更新日期：2019-02-13 00:00:00

abstract：:The killer toxin K1 is a virally encoded fungal A/B toxin acting by disrupting plasma membrane integrity. The connection of α and β constitutes a critical feature for toxin biology and for decades the formation of three disulphide bonds linking the major toxin subunits was accepted as status quo. Due to the absence of...

journal_title：Scientific reports

authors： Gier S,Lermen M,Schmitt MJ,Breinig F

更新日期：2019-09-11 00:00:00

abstract：:This study explores the radiation field temperatures introduced by the laser spot, the re-emitting wall in a hohlraum and the entire hohlraum drive source. This investigation, which is the first of its kind, is based on the radiation fluxes from the laser spot and the re-emitting wall, which have been accurately measu...

journal_title：Scientific reports

authors： Ren K,Liu S,Xie X,Du H,Hou L,Jing L,Yang D,Zhao Y,Yan J,Yang Z,Li Z,Dong J,Yang G,Li S,Cao Z,Lan K,Huo W,Liu J,Ren G,Ding Y,Jiang S

更新日期：2019-03-25 00:00:00

abstract：:Stylopine is a protoberberine-type alkaloid that has potential biological activities. Based on the successful microbial production of (S)-reticuline, we attempted to produce stylopine from (S)-reticuline by the reaction of berberine bridge enzyme, cheilanthifoline synthase (CYP719A5), and stylopine synthase (CYP719A2)...

journal_title：Scientific reports

authors： Hori K,Okano S,Sato F

更新日期：2016-02-29 00:00:00

abstract：:Amorphophallus paeoniifolius, is a commercially important vegetable crop because of its high production potential. In this study, we generated a total of 166 Gb of genomic data from 16 wild and 20 cultivated A. paeoniifolius individuals in southwestern China using restriction site associated DNA sequencing (RAD-seq). ...

journal_title：Scientific reports

authors： Gao Y,Yin S,Wu L,Dai D,Wang H,Liu C,Tang L

更新日期：2017-10-27 00:00:00

abstract：:Light modulates global features of the important human pathogen Acinetobacter baumannii lifestyle including metabolism, tolerance to antibiotics and virulence, most of which depend on the short BLUF-type photoreceptor BlsA. In this work, we show that the ability to circumvent iron deficiency is also modulated by light...

journal_title：Scientific reports

authors： Tuttobene MR,Cribb P,Mussi MA

更新日期：2018-05-16 00:00:00