Optimization of human mesenchymal stem cell manufacturing: the effects of animal/xeno-free media.

abstract：:The intensity of a nonlinear terahertz (THz) source is primarily given by its spectral density. In this letter, we introduce triangular Selinium (Se) as a novel THz emitter and show numerically its superior properties to the currently used crystals for intense THz generation. The excellent phase matching enables the a...

journal_title：Scientific reports

authors： Shalaby M,Hauri CP

更新日期：2015-01-27 00:00:00

abstract：:Boolean networks are widely used to model gene regulatory networks and to design therapeutic intervention strategies to affect the long-term behavior of systems. In this paper, we investigate the less-studied one-bit perturbation, which falls under the category of structural intervention. Previous works focused on fin...

journal_title：Scientific reports

authors： Hu M,Shen L,Zan X,Shang X,Liu W

更新日期：2016-05-19 00:00:00

abstract：:The transition from unicellular to multicellular organisms poses the question as to when genes that regulate cell-cell interactions emerged during evolution. The receptor and ligand pairing of plexins and semaphorins regulates cellular interactions in a wide range of developmental and physiological contexts. We survey...

journal_title：Scientific reports

authors： Junqueira Alves C,Yotoko K,Zou H,Friedel RH

更新日期：2019-02-13 00:00:00

abstract：:Lysophospholipids (LPLs) are known to have potentially important roles in the initiation and maintenance of neuropathic pain in animal models. This study investigated the association between the clinical severity of lumbar spinal stenosis (LSS) and the cerebrospinal fluid (CSF) levels of LPLs, using human samples. We ...

journal_title：Scientific reports

authors： Hayakawa K,Kurano M,Ohya J,Oichi T,Kano K,Nishikawa M,Uranbileg B,Kuwajima K,Sumitani M,Tanaka S,Aoki J,Yatomi Y,Chikuda H

更新日期：2019-06-24 00:00:00

abstract：:Heating on the microscale using focused lasers gave rise to recent applications, e.g., in biomedicine, biology and microfluidics, especially using gold nanoparticles as efficient nanoabsorbers of light. However, such an approach naturally leads to nonuniform, Gaussian-like temperature distributions due to the diffusiv...

journal_title：Scientific reports

authors： Durdevic L,Robert HML,Wattellier B,Monneret S,Baffou G

更新日期：2019-03-15 00:00:00

abstract：:Hypertension is a public health issue in Iran. The study aimed to estimate the prevalence, awareness, treatment, and control of hypertension, and to explore their determinants among 10,040 Kurdish adults from Ravansar Non-Communicable Disease (RaNCD) cohort study in Iran. Univariate, and multivariate analyses were use...

journal_title：Scientific reports

authors： Rajati F,Hamzeh B,Pasdar Y,Safari R,Moradinazar M,Shakiba E,Bazargan-Hejazi S,Karim H,Najafi F

更新日期：2019-08-27 00:00:00

abstract：:We report a water decomposition mode called 'Aquaionic Splitting (AiS)' by means of iron corrosion in aqueous solution. In this paper, we investigated the phenomenon by controlling the reaction between iron and water. A pseudo-sacrificial protection method with oil paint was employed to select the anode and cathode fo...

journal_title：Scientific reports

authors： Murakami S,Zhang L,Watanabe S

更新日期：2020-02-03 00:00:00

abstract：:Aryl nitriles are versatile compounds that can be synthesized via transition-metal-mediated cyanation of aryl halides. Most of the supported-heterogeneous catalysts are noble-metals based and there are very limited numbers of efficient non-noble metal based catalysts demonstrated for the cyanation of aryl halides. Her...

journal_title：Scientific reports

authors： Mayakrishnan G,Elayappan V,Kim IS,Chung IM

更新日期：2020-01-20 00:00:00

abstract：:Cell survival is facilitated by the maintenance of mitochondrial membrane potential (MMP). B cell activating factor (BAFF) plays a role in survival, differentiation, and maturation of B cells. In the present study, we examined whether BAFF could attenuate oxidative stress-induced B cell death by the regulation of MMP ...

journal_title：Scientific reports

authors： Park S,Jang JW,Moon EY

更新日期：2020-07-16 00:00:00

abstract：:Peach is an economically import fruit crop worldwide, and serves as a model species of the Rosaceae family as well. However, peach functional genomics studies are severely hampered due to its recalcitrance to regeneration and stable transformation. Here, we report a fast and efficient Agrobacterium rhizogenes-mediated...

journal_title：Scientific reports

authors： Xu S,Lai E,Zhao L,Cai Y,Ogutu C,Cherono S,Han Y,Zheng B

更新日期：2020-02-18 00:00:00

abstract：:Human travel impacts the spread of infectious diseases across spatial and temporal scales, with broad implications for the biological and social sciences. Individual data on travel patterns have been difficult to obtain, particularly in low-income countries. Travel survey data provide detailed demographic information,...

journal_title：Scientific reports

authors： Wesolowski A,Stresman G,Eagle N,Stevenson J,Owaga C,Marube E,Bousema T,Drakeley C,Cox J,Buckee CO

更新日期：2014-07-14 00:00:00

abstract：:Rivers are an important aquatic conduit that connects terrestrial sources of dissolved inorganic carbon (DIC) and other elements with oceanic reservoirs. The Mekong River, one of the world's largest rivers, is firstly examined to explore inter-annual fluxes of dissolved and particulate constituents during 1923-2011 an...

journal_title：Scientific reports

authors： Li S,Bush RT

更新日期：2015-11-02 00:00:00

abstract：:We report on the magnetic field control of a bipolar resistive switching in Ag/TiO2/FTO based resistive random access memory device through I-V characteristics. Essentially, in the presence of magnetic field and in the low resistance state, an abrupt change in the resistance of the device demands higher voltage, hinti...

journal_title：Scientific reports

authors： Sahu DP,Jammalamadaka SN

更新日期：2017-12-08 00:00:00

abstract：:Due to their small dimensions, electrophysiology on thin and intricate axonal branches in support of understanding their role in normal and diseased brain function poses experimental challenges. To reduce experimental complexity, we coupled microelectrode arrays (MEAs) to bi-level microchannel devices for the long-ter...

journal_title：Scientific reports

authors： Habibey R,Latifi S,Mousavi H,Pesce M,Arab-Tehrany E,Blau A

更新日期：2017-08-17 00:00:00

abstract：:Lipases are interfacially activated enzymes that catalyze the hydrolysis of ester bonds and constitute prime candidates for industrial and biotechnological applications ranging from detergent industry, to chiral organic synthesis. As a result, there is an incentive to understand the mechanisms underlying lipase activi...

journal_title：Scientific reports

authors： Bohr SS,Lund PM,Kallenbach AS,Pinholt H,Thomsen J,Iversen L,Svendsen A,Christensen SM,Hatzakis NS

更新日期：2019-11-07 00:00:00

abstract：:Tupistra chinensis is widely distributed in southwestern China and its rhizome is a famous folk medicine for the treatment of carbuncles and pharyngitis. Its chemical identity of potent antiproliferative and anti-inflammatory constituents has been carried out in this study. Twenty-three polyhydroxylated spirostanol sa...

journal_title：Scientific reports

authors： Xiang L,Yi X,Wang Y,He X

更新日期：2016-08-17 00:00:00

abstract：:SARS-CoV-2 can transmit efficiently in humans, but it is less clear which other mammals are at risk of being infected. SARS-CoV-2 encodes a Spike (S) protein that binds to human ACE2 receptor to mediate cell entry. A species with a human-like ACE2 receptor could therefore be at risk of being infected by SARS-CoV-2. We...

journal_title：Scientific reports

authors： Wei Y,Aris P,Farookhi H,Xia X

更新日期：2021-01-18 00:00:00

abstract：:Aminopeptidases have emerged as new promising drug targets for the development of novel anti-parasitic drugs. An aspartyl aminopeptidase-like gene has been identified in the Toxoplasma gondii genome (TgAAP), although its function remains unknown. In this study, we characterized TgAAP and performed functional analysis ...

journal_title：Scientific reports

authors： Zheng J,Cheng Z,Jia H,Zheng Y

更新日期：2016-09-28 00:00:00

abstract：:The widespread use of electric light and electronic devices has resulted in an excessive exposure to light during the late-evening and at night. This late light exposure acutely suppresses melatonin and sleepiness and delays the circadian clock. Here we investigate whether the acute effects of late-evening light expos...

journal_title：Scientific reports

authors： Te Kulve M,Schlangen LJM,van Marken Lichtenbelt WD

更新日期：2019-11-05 00:00:00

abstract：:The charge transport properties of hybrid halide perovskites are investigated with a combination of density functional theory including van der Waals interaction and the Boltzmann theory for diffusive transport in the relaxation time approximation. We find the mobility of electrons to be in the range 5-10 cm(2)V(-1)s(...

journal_title：Scientific reports

authors： Motta C,El-Mellouhi F,Sanvito S

更新日期：2015-08-03 00:00:00

abstract：:Age-related hearing loss (ARHI) is the most common sensory disorder in the elderly. Although telomere attrition has been shown as a determinant in the pathobiology of various age-related diseases, it remains unknown whether telomere length is associated with ARHI. We hypothesized that decreased leukocyte telomere leng...

journal_title：Scientific reports

authors： Liu H,Luo H,Yang T,Wu H,Chen D

更新日期：2017-08-31 00:00:00

abstract：:Distance, environmental heterogeneity and local adaptation can strongly influence population structure and connectivity. Understanding how these factors shape the genomic landscape of threatened species is a major goal in conservation genomics and wildlife management. Herein, we use thousands (6,859) of single nucleot...

journal_title：Scientific reports

authors： Sánchez-Ramírez S,Rico Y,Berry KH,Edwards T,Karl AE,Henen BT,Murphy RW

更新日期：2018-07-25 00:00:00

abstract：:Sheepgrass (Leymus chinensis) is one of the dominant grass species present on typical steppes of the Inner Mongolia Plateau. However, L. chinensis has developed a dwarfing phenotype in response to the stressful habitat in grasslands that are severely degraded due to heavy grazing. The lack of transcriptomic and genomi...

journal_title：Scientific reports

authors： Ren W,Hou X,Wu Z,Kong L,Guo H,Hu N,Wan D,Zhang J

更新日期：2018-12-17 00:00:00

abstract：:Desert locusts (Schistocerca gregaria) show a dramatic form of socially induced phenotypic plasticity known as phase polyphenism. In the absence of conspecifics, locusts occur in a shy and cryptic solitarious phase. Crowding with conspecifics drives a behavioural transformation towards gregariousness that occurs withi...

journal_title：Scientific reports

authors： Mallon EB,Amarasinghe HE,Ott SR

更新日期：2016-10-18 00:00:00

abstract：:Aluminium adjuvants remain the most widely used and effective adjuvants in vaccination and immunotherapy. Herein, the particle size distribution (PSD) of aluminium oxyhydroxide and aluminium hydroxyphosphate adjuvants was elucidated in attempt to correlate these properties with the biological responses observed post v...

journal_title：Scientific reports

authors： Mold M,Shardlow E,Exley C

更新日期：2016-08-12 00:00:00

abstract：:Ocular graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation (HSCT). Here we compared the diagnostic rates of ocular GVHD, including its severity, prognosis and the agreement, obtained using three grading scales: the National Institutes of Health (NIH) eye score, Japan...

journal_title：Scientific reports

authors： Tatematsu Y,Ogawa Y,Abe T,Kamoi M,Uchino M,Saijo-Ban Y,Yaguchi S,Mukai S,Mori T,Okamoto S,Tsubota K

更新日期：2014-10-22 00:00:00

abstract：:Voltage-gated potassium (Kv) channels comprise pore-forming α subunits and a multiplicity of regulatory proteins, including the cardiac-expressed and cardiac arrhythmia-linked transmembrane KCNE subunits. After recently uncovering novel, N-terminally extended (L) KCNE3 and KCNE4 isoforms and detecting their transcript...

journal_title：Scientific reports

authors： Abbott GW

更新日期：2016-12-06 00:00:00

abstract：:Low pH in the tumor micromilieu is a recognized pathological feature of cancer. This attribute of cancerous cells has been targeted herein for the controlled release of chemotherapeutics at the tumour site, while sparing healthy tissues. To this end, pH-sensitive, hollow ZnO-nanocarriers loaded with paclitaxel were sy...

journal_title：Scientific reports

authors： Puvvada N,Rajput S,Kumar BNP,Sarkar S,Konar S,Brunt KR,Rao RR,Mazumdar A,Das SK,Basu R,Fisher PB,Mandal M,Pathak A

更新日期：2015-07-06 00:00:00

abstract：:Regular drusen, an accumulation of material below the retinal pigment epithelium (RPE), have long been established as a hallmark early feature of nonneovascular age-related macular degeneration (AMD). Advances in imaging have expanded the phenotype of AMD to include another extracellular deposit, reticular pseudodruse...

journal_title：Scientific reports

authors： Mishra Z,Ganegoda A,Selicha J,Wang Z,Sadda SR,Hu Z

更新日期：2020-06-12 00:00:00

abstract：:Some studies have reported that upper limb tightness is a risk factor for shoulder/elbow pain in high school baseball pitchers; but there has been insufficient research on the relationship between lower limb tightness and shoulder and elbow pain in pitchers. This study aimed to clarify the correlation among pre-season...

journal_title：Scientific reports

authors： Hamano N,Shitara H,Tajika T,Ichinose T,Sasaki T,Kamiyama M,Miyamoto R,Kuboi T,Endo F,Yamamoto A,Takagishi K,Chikuda H

更新日期：2020-11-17 00:00:00