Correlation between Ultrasound Elastography and Histologic Characteristics of Papillary Thyroid Carcinoma.

Abstract:

:The aim of this study was to investigate the correlation between elastography and histologic characteristics including fibrosis and calcification. We also wanted to investigate whether other clinicopathologic indexes influence the strain ratio (SR) of papillary thyroid carcinomas (PTCs). We retrospectively reviewed 126 papillary thyroid carcinomas (PTCs) from 103 patients who underwent ultrasonography and elastography before surgery. The histologic characteristics and clinicopathologic indexes were compared with the SR of ultrasound elastography (UE). The results showed that there was a significantly positive correlation between fibrosis degree and SR measurements (r = 0.754, p = 0.000); the SR was significantly different between the groups with and without calcification (11.34 ± 10.08 vs. 6.81 ± 7.33, p = 0.000). The standard coefficients of collagen and stromal calcification were 0.684 and 0.194, respectively. There was no significant correlation between SR and indices such as size, position, co-existence with Hashimoto's thyroiditis (HT), multifocality or cervical lymph node (CLN) metastasis. In conclusion, we found that the SR of UE is positively correlated with the fibrosis of PTC. Stromal calcification will elevate the SR dramatically, but psammoma bodies will not when they exist in the absence of stromal calcification.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Yi L,Qiong W,Yan W,Youben F,Bing H

doi

10.1038/srep45042

subject

Has Abstract

pub_date

2017-03-22 00:00:00

pages

45042

issn

2045-2322

pii

srep45042

journal_volume

7

pub_type

杂志文章
  • Stereopsis and retinal microstructures following macular hole surgery.

    abstract::The aim of this prospective study was to evaluate the changes in stereopsis in patients who underwent vitrectomy for macular hole (MH) and assess the relationship between stereopsis and retinal microstructures. Fifty-two patients who underwent successful vitrectomy for unilateral MH and 20 control participants were re...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-76648-4

    authors: Okamoto F,Moriya Y,Sugiura Y,Murakami T,Morikawa S,Hoshi S,Hiraoka T,Oshika T

    更新日期:2020-11-11 00:00:00

  • Lifetime risks, expected years of life lost, and cost-per-life year of esophageal cancer in Taiwan.

    abstract::Besides lifetime risks, we estimated life expectancy (LE), expected years of life lost (EYLL), lifetime costs, and cost-per-LY (life-year) stratified by different stages of esophageal cancer (EC). From the Taiwan Cancer Registry, we collected 14,420 EC to estimate the incidence rates during 2008-2014. They were follow...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-60701-3

    authors: Lai WW,Lin CN,Chang CC,Wang JD

    更新日期:2020-02-28 00:00:00

  • Using Artificial Intelligence and Novel Polynomials to Predict Subjective Refraction.

    abstract::This work aimed to use artificial intelligence to predict subjective refraction from wavefront aberrometry data processed with a novel polynomial decomposition basis. Subjective refraction was converted to power vectors (M, J0, J45). Three gradient boosted trees (XGBoost) algorithms were trained to predict each power ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-65417-y

    authors: Rampat R,Debellemanière G,Malet J,Gatinel D

    更新日期:2020-05-22 00:00:00

  • Interaction of Caveolin-3 and HCN is involved in the pathogenesis of diabetic cystopathy.

    abstract::A growing body of research suggests that impaired bladder Cajal-like interstitial cells (ICCs) are a important component in the pathogenesis of diabetes-induced bladder dysfunction, although the molecular mechanisms have not been illustrated completely. The purpose of this study was to examine whether the hyperpolariz...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24844

    authors: Dong X,Song Q,Zhu J,Zhao J,Liu Q,Zhang T,Long Z,Li J,Wu C,Wang Q,Hu X,Damaser M,Li L

    更新日期:2016-04-28 00:00:00

  • The immune mediated role of extracellular HMGB1 in a heterotopic model of bladder cancer radioresistance.

    abstract::Radical cystectomy (RC) together with bilateral pelvic lymph node dissection remains the standard treatment for muscle invasive bladder cancer (MIBC). However, radiation-based treatments such as tri-modal therapy (TMT) involving maximally performed transurethral resection of bladder tumor (TURBT), radiotherapy (XRT), ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-42864-w

    authors: Ayoub M,Shinde-Jadhav S,Mansure JJ,Alvarez F,Connell T,Seuntjens J,Piccirillo CA,Kassouf W

    更新日期:2019-04-23 00:00:00

  • The depleted mineralization of the fungicide chlorothalonil derived from loss in soil microbial diversity.

    abstract::There are lack of studies regarding the effects of microbial diversity on specific soil functions, such as pesticides degradation. This study evaluated the role of bacterial community diversity and biochar on chlorothalonil (CTN) degradation, using 'dilution to extinction' approach, PCR-DGGE/16S rRNA gene technique, a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-14803-0

    authors: de Souza AJ,de Andrade PAM,de Araújo Pereira AP,Andreote FD,Tornisielo VL,Regitano JB

    更新日期:2017-11-07 00:00:00

  • Preserved neurogenesis in non-demented individuals with AD neuropathology.

    abstract::Rare individuals remain cognitively intact despite the presence of neuropathology usually associated with fully symptomatic Alzheimer's disease (AD), which we refer to as Non-Demented with Alzheimer's disease Neuropathology (NDAN). Understanding the involved mechanism(s) of their cognitive resistance may reveal novel ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep27812

    authors: Briley D,Ghirardi V,Woltjer R,Renck A,Zolochevska O,Taglialatela G,Micci MA

    更新日期:2016-06-14 00:00:00

  • Comparison of phosphorylation and assembly of photosystem complexes and redox homeostasis in two wheat cultivars with different drought resistance.

    abstract::Reversible phosphorylation of proteins and the assembly of thylakoid complexes are the important protective mechanism against environmental stresses in plants. This research was aimed to investigate the different responses of the antioxidant defense system and photosystem II (PSII) to osmotic stress between drought-re...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13145-1

    authors: Chen YE,Cui JM,Su YQ,Zhang CM,Ma J,Zhang ZW,Yuan M,Liu WJ,Zhang HY,Yuan S

    更新日期:2017-10-05 00:00:00

  • Multi-wavelength growth of nanosecond laser-induced surface damage on fused silica gratings.

    abstract::The nanosecond laser-induced damage growth phenomenon on the exit surface of fused silica grating is investigated at 1064 nm and 355 nm separately and also simultaneously. Experiments are first carried out on damage sites on a plane fused silica sample showing two different morphologies, and a damage type is selected ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18957-9

    authors: Chambonneau M,Lamaignère L

    更新日期:2018-01-17 00:00:00

  • Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes.

    abstract::Hepatitis C virus (HCV) infection of hepatocytes promotes liver fibrosis by activation of hepatic stellate cells (HSCs) and excessive deposition of extracellular matrix in liver tissue. Whether or not host factors released from the HCV-infected hepatocytes play role in HSCs activation is unclear. In this study, HSCs w...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04259-7

    authors: Cheng JC,Tseng CP,Liao MH,Peng CY,Yu JS,Chuang PH,Huang JT,Chen JJW

    更新日期:2017-06-30 00:00:00

  • AutoImpute: Autoencoder based imputation of single-cell RNA-seq data.

    abstract::The emergence of single-cell RNA sequencing (scRNA-seq) technologies has enabled us to measure the expression levels of thousands of genes at single-cell resolution. However, insufficient quantities of starting RNA in the individual cells cause significant dropout events, introducing a large number of zero counts in t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-34688-x

    authors: Talwar D,Mongia A,Sengupta D,Majumdar A

    更新日期:2018-11-05 00:00:00

  • Spin polarization of excitons in organic multiferroic composites.

    abstract::Recently, the discovery of room temperature magnetoelectricity in organic charge transfer complexes has reignited interest in the multiferroic field. The solution processed, large-area and low cost organic semiconductor materials offer new possibilities for the functional all organic multiferroic devices. Here we repo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28656

    authors: Han S,Yang L,Gao K,Xie S,Qin W,Ren S

    更新日期:2016-06-23 00:00:00

  • The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata.

    abstract::SeviL is a recently isolated lectin found to bind to the linear saccharides of the ganglioside GM1b (Neu5Ac[Formula: see text](2-3)Gal[Formula: see text](1-3)GalNAc[Formula: see text](1-4)Gal[Formula: see text](1-4)Glc) and its precursor, asialo-GM1 (Gal[Formula: see text](1-3)GalNAc[Formula: see text](1-4)Gal[Formula...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-78926-7

    authors: Kamata K,Mizutani K,Takahashi K,Marchetti R,Silipo A,Addy C,Park SY,Fujii Y,Fujita H,Konuma T,Ikegami T,Ozeki Y,Tame JRH

    更新日期:2020-12-16 00:00:00

  • Genetic diversity and population structure of the Bacillus cereus group bacteria from diverse marine environments.

    abstract::The phylogenetic diversity of marine bacteria belonged to the Bacillus cereus group has not been well investigated. Here, we present the genetic diversity and population structure of 71 bacteria from diverse marine environments, using a multilocus sequence typing (MLST) approach and the analyses of digital DNA-DNA hyb...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00817-1

    authors: Liu Y,Lai Q,Du J,Shao Z

    更新日期:2017-04-06 00:00:00

  • Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals.

    abstract::The study of postsynaptic excitation to inhibition (E/I ratio) imbalances in human brain diseases, is a highly relevant functional measurement poorly investigated due to postmortem degradation of synaptic receptors. We show that near-simultaneous recording of microtransplanted synaptic receptors after simulated morgue...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-65377-3

    authors: Scaduto P,Sequeira A,Vawter MP,Bunney W,Limon A

    更新日期:2020-05-25 00:00:00

  • Spatio-temporal analysis of malaria incidence in the Peruvian Amazon Region between 2002 and 2013.

    abstract::Malaria remains a major public health problem in the Peruvian Amazon where the persistence of high-risk transmission areas (hotspots) challenges the current malaria control strategies. This study aimed at identifying significant space-time clusters of malaria incidence in Loreto region 2002-2013 and to determine signi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep40350

    authors: Soto-Calle V,Rosas-Aguirre A,Llanos-Cuentas A,Abatih E,DeDeken R,Rodriguez H,Rosanas-Urgell A,Gamboa D,D Alessandro U,Erhart A,Speybroeck N

    更新日期:2017-01-16 00:00:00

  • Plasma channel formation in NIR laser-irradiated carrier gas from an aerosol nanoparticle injector.

    abstract::Aerosol nanoparticle injectors are fundamentally important for experiments where container-free sample handling is needed to study isolated nanoparticles. The injector consists of a nebuliser, a differential pumping unit, and an aerodynamic lens to create and deliver a focused particle beam to the interaction point in...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-45120-3

    authors: Klimešová E,Kulyk O,Gu Y,Dittrich L,Korn G,Hajdu J,Krikunova M,Andreasson J

    更新日期:2019-06-20 00:00:00

  • Towards ultimate low frequency air-core magnetometer sensitivity.

    abstract::Air-core magnetometers are amongst the most commonly used magnetic field detectors in biomedical instruments. They offer excellent sensitivity, low fabrication complexity and a robust, cost-effective solution. However, air-core magnetometers must be tailored to the specific application to achieve high sensitivity, whi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-02099-z

    authors: Pellicer-Guridi R,Vogel MW,Reutens DC,Vegh V

    更新日期:2017-05-23 00:00:00

  • Resolving the Architecture and Early Evolution of a Forearc Basin (Georgia Basin, Canada) Using Detrital Zircon.

    abstract::Convergent-margin basins (CMBs) are commonly associated with active arcs, and hence are rich in detrital zircon (DZ) whose ages closely reflect the timing of deposition. Consequently, maximum depositional ages (MDA) from DZ geochronology can be employed to resolve the stratigraphy and evolution of CMBs. Herein, we use...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-51795-5

    authors: Huang C,Dashtgard SE,Kent BAP,Gibson HD,Matthews WA

    更新日期:2019-10-25 00:00:00

  • Prion protein modulates glucose homeostasis by altering intracellular iron.

    abstract::The prion protein (PrPC), a mainly neuronal protein, is known to modulate glucose homeostasis in mouse models. We explored the underlying mechanism in mouse models and the human pancreatic β-cell line 1.1B4. We report expression of PrPC on mouse pancreatic β-cells, where it promoted uptake of iron through divalent-met...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24786-1

    authors: Ashok A,Singh N

    更新日期:2018-04-26 00:00:00

  • A Clinically Relevant Functional Model of Type-2 Cardio-Renal Syndrome with Paraventricular Changes consequent to Chronic Ischaemic Heart Failure.

    abstract::Cardiorenal syndrome, de novo renal pathology arising secondary to cardiac insufficiency, is clinically recognised but poorly characterised. This study establishes and characterises a valid model representative of Type 2 cardiorenal syndrome. Extensive permanent left ventricular infarction, induced by ligation of the ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-58071-x

    authors: Harrison JC,Smart SDG,Besley EMH,Kelly JR,Read MI,Yao Y,Sammut IA

    更新日期:2020-01-27 00:00:00

  • Plastic flow anisotropy drives shear fracture.

    abstract::Fracture of initially crack-free bodies often occurs due to plastic instabilities known as shear bands. Previous computer simulations advanced a myriad of mechanisms to rationalize shear banding. However, they were restricted to planar geometries. We investigate the relevance of anisotropic plasticity by picking an ax...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-38437-y

    authors: Benzerga AA,Thomas N,Herrington JS

    更新日期:2019-02-05 00:00:00

  • Rattlesnakes are extremely fast and variable when striking at kangaroo rats in nature: Three-dimensional high-speed kinematics at night.

    abstract::Predation plays a central role in the lives of most organisms. Predators must find and subdue prey to survive and reproduce, whereas prey must avoid predators to do the same. The resultant antagonistic coevolution often leads to extreme adaptations in both parties. Few examples capture the imagination like a rapid str...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep40412

    authors: Higham TE,Clark RW,Collins CE,Whitford MD,Freymiller GA

    更新日期:2017-01-13 00:00:00

  • Gene expression of Lactobacillus plantarum and the commensal microbiota in the ileum of healthy and early SIV-infected rhesus macaques.

    abstract::Chronic HIV infection results in impairment of gut-associated lymphoid tissue leading to systemic immune activation. We previously showed that in early SIV-infected rhesus macaques intestinal dysfunction is initiated with the induction of the IL-1β pathway in the small intestine and reversed by treatment with an exoge...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24723

    authors: Golomb BL,Hirao LA,Dandekar S,Marco ML

    更新日期:2016-04-22 00:00:00

  • Noncanonical NF-κB mediates the Suppressive Effect of Neutrophil Elastase on IL-8/CXCL8 by Inducing NKRF in Human Airway Smooth Muscle.

    abstract::Neutrophil elastase (NE) suppresses IL-8/CXCL8 in human airway smooth muscle cells (hASM) while stimulating its production in respiratory epithelial cells. This differential effect is mediated by the selective induction of NKRF and dysregulation in chronic inflammatory diseases. We hypothesized that the differential a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep44930

    authors: Ho SC,Wu SM,Feng PH,Liu WT,Chen KY,Chuang HC,Chan YF,Kuo LW,Lee KY

    更新日期:2017-03-21 00:00:00

  • Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.

    abstract::Sideroflexin4 (SFXN4) is a member of a family of nuclear-encoded mitochondrial proteins. Rare germline mutations in SFXN4 lead to phenotypic characteristics of mitochondrial disease including impaired mitochondrial respiration and hematopoetic abnormalities. We sought to explore the function of this protein. We show t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-55907-z

    authors: Paul BT,Tesfay L,Winkler CR,Torti FM,Torti SV

    更新日期:2019-12-23 00:00:00

  • A five-year longitudinal observational study in morbidity and mortality of negative appendectomy in Sulaimani teaching Hospital/Kurdistan Region/Iraq.

    abstract::The most common surgical emergency is suspected acute appendicitis, the lifetime risk of acute appendicitis is estimated to be 8.6% for men and 6.7% for women, with a male to female ratio of 1.4:1; correct diagnosis can be made in 70-80% of patients after the operations about 32% of appendectomies revealed normal appe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-58847-1

    authors: Ahmed HO,Muhedin R,Boujan A,Aziz AHS,Abdulla AM,Hardi RA,Abdulla AA,Sidiq TA

    更新日期:2020-02-06 00:00:00

  • Matching relations for optimal entanglement concentration and purification.

    abstract::The bilateral controlled NOT (CNOT) operation plays a key role in standard entanglement purification process, but the CNOT operation may not be the optimal joint operation in the sense that the output entanglement is maximized. In this paper, the CNOT operations in both the Schmidt-projection based entanglement concen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25958

    authors: Kong FZ,Xia HZ,Yang M,Yang Q,Cao ZL

    更新日期:2016-05-18 00:00:00

  • Chocolate for breakfast prevents circadian desynchrony in experimental models of jet-lag and shift-work.

    abstract::Night-workers, transcontinental travelers and individuals that regularly shift their sleep timing, suffer from circadian desynchrony and are at risk to develop metabolic disease, cancer, and mood disorders, among others. Experimental and clinical studies provide evidence that food intake restricted to the normal activ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-63227-w

    authors: Escobar C,Espitia-Bautista E,Guzmán-Ruiz MA,Guerrero-Vargas NN,Hernández-Navarrete MÁ,Ángeles-Castellanos M,Morales-Pérez B,Buijs RM

    更新日期:2020-04-10 00:00:00

  • Individual differences predict endorsement of water resilience.

    abstract::In the epoch of the Anthropocene change, complexity, and uncertainty create a demand for new systems of water management and governance. One such management model that is rapidly gaining traction amongst both scholars and practitioners is the concept of water resilience. Although increasing attention has been paid to ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62896-x

    authors: Baird J,Dale G,Farhad S

    更新日期:2020-04-06 00:00:00