Preserved neurogenesis in non-demented individuals with AD neuropathology.

abstract：:Sodium taurocholate cotransporting polypeptide (NTCP) is a recently discovered hepatitis B virus (HBV) receptor. In the present study, we used TK-NOG mice with a humanized liver to examine the impact of endogenous NTCP expression on HBV infection. Upon inoculation with HBV, these mice exhibited clear viremia in 2 week...

journal_title：Scientific reports

authors： Nakabori T,Hikita H,Murai K,Nozaki Y,Kai Y,Makino Y,Saito Y,Tanaka S,Wada H,Eguchi H,Takahashi T,Suemizu H,Sakamori R,Hiramatsu N,Tatsumi T,Takehara T

更新日期：2016-06-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： An T,Fan T,Zhang XQ,Liu YF,Huang J,Liang C,Lv BH,Wang YQ,Zhao XG,Liu JX,Fu YH,Jiang GJ

更新日期：2020-04-22 00:00:00

abstract：:Microstructures in nature are ultrafine and ordered in biological roles, which have attracted material scientists. Spirulina forms three-dimensional helical microstructure, one of remarkable features in nature beyond our current processing technology such as lithography in terms of mass-productivity and structural mul...

journal_title：Scientific reports

authors： Kamata K,Piao Z,Suzuki S,Fujimori T,Tajiri W,Nagai K,Iyoda T,Yamada A,Hayakawa T,Ishiwara M,Horaguchi S,Belay A,Tanaka T,Takano K,Hangyo M

更新日期：2014-05-12 00:00:00

abstract：:For the first time, high-surface-area (approximately 1465 m(2) g(-1)), highly porous and heteroatom-enriched activated carbon (HAC) was prepared from banana stems (Musa paradisiaca, Family: Musaceae) at different carbonization temperatures of 700, 800 and 900 °C (HAC) using a simple and eco-friendly method. The amount...

journal_title：Scientific reports

authors： Madhu R,Veeramani V,Chen SM

更新日期：2014-04-23 00:00:00

abstract：:Cyclin Y (CCNY) is a member of the cyclin protein family, known to regulate cell division in proliferating cells. Interestingly, CCNY is expressed in neurons that do not undergo cell division. Here, we report that CCNY negatively regulates long-term potentiation (LTP) of synaptic strength through inhibition of AMPA re...

journal_title：Scientific reports

authors： Cho E,Kim DH,Hur YN,Whitcomb DJ,Regan P,Hong JH,Kim H,Ho Suh Y,Cho K,Park M

更新日期：2015-07-29 00:00:00

abstract：:Glutamate (Glu), the key excitatory neurotransmitter in the central nervous system, is considered essential for brain functioning and has a vital role in learning and memory formation. Earlier it was considered as a harmful agent but later found to be useful for many body functions. However, studies regarding the effe...

journal_title：Scientific reports

authors： Tabassum S,Ahmad S,Madiha S,Shahzad S,Batool Z,Sadir S,Haider S

更新日期：2020-07-08 00:00:00

abstract：:Spiny mice of the genus Acomys display several unique physiological traits, including menstruation and scar-free wound healing; characteristics that are exceedingly rare in mammals, and of considerable interest to the scientific community. These unique attributes, and the potential for spiny mice to accurately model h...

journal_title：Scientific reports

authors： Mamrot J,Legaie R,Ellery SJ,Wilson T,Seemann T,Powell DR,Gardner DK,Walker DW,Temple-Smith P,Papenfuss AT,Dickinson H

更新日期：2017-08-21 00:00:00

abstract：:Early antiretroviral therapy (ART) initiation is a recommended public health approach for the prevention of HIV-1 transmission. In this cohort study, we included 13132 serodiscordant couples. ART was initiated for patients with CD4+ T cell counts less than 200 cells/uL, 350 cells/uL, and 500 cells/uL respectively. Thi...

journal_title：Scientific reports

authors： Liu P,Tang Z,Lan G,Zhu Q,Chen H,You Y,Yang X,Liang S,Chen Y,Xing H,Liao L,Feng Y,Shen Z,Ruan Y,Shao Y

更新日期：2018-02-21 00:00:00

abstract：:Transverse-tubules (T-tubules) play pivotal roles in Ca2+-induced, Ca2+ release and excitation-contraction coupling in cardiomyocytes. The purpose of this study was to uncover mechanisms where sarco/endoplasmic reticulum Ca2+ ATPase (SERCA2a) improved cardiac function through T-tubule regulation during myocardial isch...

journal_title：Scientific reports

authors： Wang S,Zhou Y,Luo Y,Kan R,Chen J,Xuan H,Wang C,Chen J,Xu T,Li D

更新日期：2021-01-21 00:00:00

abstract：:One of the ways dredging can affect benthic habitats is through high levels of sediment deposition, which has the potential to smother sessile organisms such as sponges. In order to provide pressure-response values to sedimentation and tease apart the different cause-effect pathways of high turbidity, 5 sponge species...

journal_title：Scientific reports

authors： Pineda MC,Strehlow B,Sternel M,Duckworth A,Haan JD,Jones R,Webster NS

更新日期：2017-07-14 00:00:00

abstract：:Rather than the conventional concept of viewing conductive carbon black (CB) to be chemically inert in microbial electrochemical cells (MECs), here we confirmed the redox activity of CB for its feasibility as an electron sink in the microbial battery (MB). Acting as the cathode of a MB, the solid-state CB electrode sh...

journal_title：Scientific reports

authors： Zhang X,Guo K,Shen D,Feng H,Wang M,Zhou Y,Jia Y,Liang Y,Zhou M

更新日期：2017-08-01 00:00:00

abstract：:High-grade gliomas are the most aggressive malignant brain tumors. Accurate pre-operative prognosis for this cohort can lead to better treatment planning. Conventional survival prediction based on clinical information is subjective and could be inaccurate. Recent radiomics studies have shown better prognosis by using ...

journal_title：Scientific reports

authors： Nie D,Lu J,Zhang H,Adeli E,Wang J,Yu Z,Liu L,Wang Q,Wu J,Shen D

更新日期：2019-01-31 00:00:00

abstract：:We studied whether in patients with stable COPD blood gases (BG), especially oxygenated hemoglobin (OxyHem) as a novel biomarker confer information on disease burden and prognosis and how this adds to the information provided by the comorbidity pattern and systemic inflammation. Data from 2137 patients (GOLD grades 1-...

journal_title：Scientific reports

authors： Trudzinski FC,Jörres RA,Alter P,Kahnert K,Waschki B,Herr C,Kellerer C,Omlor A,Vogelmeier CF,Fähndrich S,Watz H,Welte T,Jany B,Söhler S,Biertz F,Herth F,Kauczor HU,Bals R,COSYCONET consortium.

更新日期：2020-06-29 00:00:00

abstract：:Many remarkable properties of graphene are derived from its large energy window for Dirac-like electronic states and have been explored for applications in electronics and photonics. In addition, strong electron-phonon interaction in graphene has led to efficient photo-thermo energy conversions, which has been harness...

journal_title：Scientific reports

authors： Tian Y,Tian H,Wu YL,Zhu LL,Tao LQ,Zhang W,Shu Y,Xie D,Yang Y,Wei ZY,Lu XH,Ren TL,Shih CK,Zhao J

更新日期：2015-06-08 00:00:00

abstract：:Full-endoscopic transforaminal lumbar discectomy (FETD) is increasingly used in patients with lumbar disc herniation (LDH). There is little knowledge on the related factors, including the straight leg raising test (SLR), that influence the operation. Consecutive patients with LDH who came to our hospital from August 2...

journal_title：Scientific reports

authors： Wei FL,Gao H,Yan X,Yuan Y,Qian S,Gao Q,Guo S,Xue W,Qian J,Zhou C

更新日期：2020-10-05 00:00:00

abstract：:Protein aggregation is a process by which misfolded proteins polymerizes into aggregates and forms fibrous structures with a β-sheet conformation, known as amyloids. It is an undesired outcome, as it not only causes numerous neurodegenerative diseases, but is also a major deterrent in the development of protein biopha...

journal_title：Scientific reports

authors： Rajan R,Matsumura K

更新日期：2017-04-04 00:00:00

abstract：:Graphene oxide is being used in energy, optical, electronic and sensor devices due to its unique properties. However, unlike its counterpart - graphene - the thermal transport properties of graphene oxide remain unknown. In this work, we use large-scale molecular dynamics simulations with reactive potentials to system...

journal_title：Scientific reports

authors： Mu X,Wu X,Zhang T,Go DB,Luo T

更新日期：2014-01-28 00:00:00

abstract：:A new miniplate applied differently from conventional application method for bone fixation has been developed. The novel approach is the insertion of the screw into the bone before miniplate installation. This study aimed to assess the stress distribution of a newly designed Yang's Keyhole (YK)- plate for segmental-bo...

journal_title：Scientific reports

authors： Kim JW,Park KN,Lee CH,Kim YS,Kim YH,Yang BE

更新日期：2018-06-12 00:00:00

abstract：:Current theoretical analyses of defect properties without solving the detailed balance equations often estimate Fermi-level pinning position by omitting free carriers and assume defect concentrations can be always tuned by atomic chemical potentials. This could be misleading in some circumstance. Here we clarify that:...

journal_title：Scientific reports

authors： Yang JH,Yin WJ,Park JS,Wei SH

更新日期：2015-11-20 00:00:00

abstract：:Complex interactions occur between tumor and host immune system at each site in the metastatic setting, the outcome of which can determine behavior ranging from dormancy to rapid growth. An additional layer of complexity arises from the understanding that cytotoxic T cells can traffic through the host circulatory syst...

journal_title：Scientific reports

authors： Walker R,Poleszczuk J,Pilon-Thomas S,Kim S,Anderson AARA,Czerniecki BJ,Harrison LB,Moros EG,Enderling H

更新日期：2018-06-21 00:00:00

abstract：:The order Chlamydiales are biphasic intracellular bacterial pathogens infecting humans and domesticated animals. Wildlife infections have also been reported, with the most studied example being Chlamydia pecorum infections in the koala, an iconic Australian marsupial. In koalas, molecular evidence suggests that spill-...

journal_title：Scientific reports

authors： Burnard D,Huston WM,Webb JK,Jelocnik M,Reiss A,Gillett A,Fitzgibbon S,Carver S,Carrucan J,Flanagan C,Timms P,Polkinghorne A

更新日期：2017-10-09 00:00:00

abstract：:The fly Ormia ochracea has the remarkable ability, given an eardrum separation of only 520 μm, to pinpoint the 5 kHz chirp of its cricket host. Previous research showed that the two eardrums are mechanically coupled, which amplifies the directional cues. We have now performed a mechanics and optimization analysis whic...

journal_title：Scientific reports

authors： Liu H,Currano L,Gee D,Helms T,Yu M

更新日期：2013-01-01 00:00:00

abstract：:In the present work, a catalyst-free physical vapour deposition method is used to synthesize high yield of Bi2Se3 nanoribbons. By replacing standard glass or quartz substrates with aluminium covered with ultrathin porous anodized aluminium oxide (AAO), the number of synthesized nanoribbons per unit area can be increas...

journal_title：Scientific reports

authors： Kunakova G,Meija R,Andzane J,Malinovskis U,Petersons G,Baitimirova M,Bechelany M,Bauch T,Lombardi F,Erts D

更新日期：2019-08-05 00:00:00

abstract：:In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...

journal_title：Scientific reports

authors： Giddey AD,de Kock E,Nakedi KC,Garnett S,Nel AJ,Soares NC,Blackburn JM

更新日期：2017-03-06 00:00:00

abstract：:Gene loss is a major contributor to the evolution of bacterial gene content. Gene loss may occur as a result of shifts in environment leading to changes in the intensity and/or directionality of selection applied for the maintenance of specific genes. Gene loss may also occur in a more neutral manner, when gene functi...

journal_title：Scientific reports

authors： Bolotin E,Hershberg R

更新日期：2016-10-13 00:00:00

abstract：:The reduced micromorphic model (RMM) is used to study the effect of the applied force on a hemisphere made of phononic crystals that belongs to the metamaterials group. The strain tensor, the micro-strain tensor and the coupling between them are the kinematic relations used to measure the deformation and micro-deforma...

journal_title：Scientific reports

authors： El Dhaba AR

更新日期：2020-02-18 00:00:00

abstract：:During spring of 2009, a new influenza virus AH1N1 spread in the world causing acute respiratory illness and death, resulting in the first influenza pandemic since 1968. Blood levels of potentially-toxic and essential elements of 40 pneumonia and confirmed AH1N1 were evaluated against two different groups of controls,...

journal_title：Scientific reports

authors： Moya M,Bautista EG,Velázquez-González A,Vázquez-Gutiérrez F,Tzintzun G,García-Arreola ME,Castillejos M,Hernández A

更新日期：2013-01-01 00:00:00

abstract：:Stress is one of major factors that cause sleep problems. Hypocretin represents a stress-related neuropeptide and is well known in maintaining physiological wakefulness. The hypocretinergic neurons originate in the lateral hypothalamic area (LHA) and transmit to several brain regions, including the median raphe nuclei...

journal_title：Scientific reports

authors： Hsiao YT,Lo Y,Yi PL,Chang FC

更新日期：2019-06-03 00:00:00

abstract：:Magnetic skyrmions are topological quasiparticles of great interest for data storage applications because of their small size, high stability, and ease of manipulation via electric current. However, although models exist for some limiting cases, there is no universal theory capable of accurately describing the structu...

journal_title：Scientific reports

authors： Büttner F,Lemesh I,Beach GSD

更新日期：2018-03-13 00:00:00

abstract：:Phytoplankton play key roles in the oceans by regulating global biogeochemical cycles and production in marine food webs. Global warming is thought to affect phytoplankton production both directly, by impacting their photosynthetic metabolism, and indirectly by modifying the physical environment in which they grow. In...

journal_title：Scientific reports

authors： D'Alelio D,Rampone S,Cusano LM,Morfino V,Russo L,Sanseverino N,Cloern JE,Lomas MW

更新日期：2020-02-25 00:00:00