Potentially-toxic and essential elements profile of AH1N1 patients in Mexico City.

Abstract:

:During spring of 2009, a new influenza virus AH1N1 spread in the world causing acute respiratory illness and death, resulting in the first influenza pandemic since 1968. Blood levels of potentially-toxic and essential elements of 40 pneumonia and confirmed AH1N1 were evaluated against two different groups of controls, both not infected with the pandemic strain. Significant concentrations of potentially-toxic elements (lead, mercury, cadmium, chromium, arsenic) along with deficiency of selenium or increased Zn/Cu ratios characterized AH1N1 cases under study when evaluated versus controlled cases. Deficiency of selenium is progressively observed from controls I (influenza like illness) through controls II (pneumonia) and finally pneumonia-AH1N1 infected patients. Cases with blood Se levels greater than the recommended for an optimal cut-off to activate glutathione peroxidase (12.5 μg/dL) recovered from illness and survived. Evaluation of this essential element in critical pneumonia patients at the National Institutes is under evaluation as a clinical trial.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Moya M,Bautista EG,Velázquez-González A,Vázquez-Gutiérrez F,Tzintzun G,García-Arreola ME,Castillejos M,Hernández A

doi

10.1038/srep01284

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

1284

issn

2045-2322

pii

srep01284

journal_volume

3

pub_type

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