Abstract:
:Pelvic disorders can be associated with changes in the biomechanical properties in the muscle, ligaments and/or connective tissue form fascia and ligaments. In this sense, the study of their mechanical behavior is important to understand the structure and function of these biological soft tissues. The aim of this study was to establish the biomechanical properties of the pelvic floor muscles of continent and incontinent women, using an inverse finite element analysis (FEA). The numerical models, including the pubovisceral muscle and pelvic bones were built from magnetic resonance (MR) images acquired at rest. The numerical simulation of Valsalva maneuver was based on the finite element method and the material constants were determined for different constitutive models (Neo-Hookean, Mooney-Rivlin and Yeoh) using an iterative process. The material constants (MPa) for Neo-Hookean (c1) were 0.039 ± 0.022 and 0.024 ± 0.004 for continent vs. incontinent women. For Mooney-Rivlin (c1) the values obtained were 0.026 ± 0.010 vs. 0.016 ± 0.003, and for Yeoh (c1) the values obtained were 0.031 ± 0.023 vs. 0.016 ± 0.002, (p < 0.05). Muscle displacements obtained in the numerical simulations of Valsalva maneuver were compared with the muscle displacements obtained through additional dynamic MRI. Incontinent women presented a higher antero-posterior displacement than the continent women. The results were also similar between MRI and numerical simulations (40.27% vs. 42.17% for Neo-Hookean, 39.87% for Mooney-Rivlin and 41.61% for Yeoh). Using an inverse FEA coupled with MR images allowed to obtain the in vivo biomechanical properties of the pelvic floor muscles, leading to a relationship between them for the continent and incontinent women in a non-invasive manner.
journal_name
Comput Methods Biomech Biomed Enginauthors
Silva MET,Brandão S,Parente MPL,Mascarenhas T,Natal Jorge RMdoi
10.1080/10255842.2017.1304542subject
Has Abstractpub_date
2017-06-01 00:00:00pages
842-852issue
8eissn
1025-5842issn
1476-8259journal_volume
20pub_type
杂志文章abstract::Marker-based motion capture presents the problem of gaps, which are traditionally processed using motion capture software, requiring intensive manual input. We propose and study an automated method of gap-filling that uses inverse kinematics (IK) to close the loop of an iterative process to minimize error, while nearl...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1789971
更新日期:2020-11-01 00:00:00
abstract::The purpose of this study is to develop a system capable of performing calculation of temporal gait parameters using two low-cost wireless accelerometers and artificial intelligence-based techniques as part of a larger research project for conducting human gait analysis. Ten healthy subjects of different ages particip...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2015.1032945
更新日期:2016-01-01 00:00:00
abstract::This article develops a two prion population model that simulates prion trafficking between an infected dendritic cell and a neuron. The situation when the two cells are connected by a tunnelling nanotube (TNT) is simulated. Two mechanisms of prion transport are considered: lateral diffusion in the TNT membrane and ac...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.763938
更新日期:2014-11-01 00:00:00
abstract::There are few previous studies on the elastic properties of ureter and most have been limited to essentially one-dimensional deformation measurements. The object of this study was, therefore, to identify regional variations in the multiaxial behaviour of rabbit ureter, subjected to in vitro inflation/extension testing...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2012.761692
更新日期:2014-11-01 00:00:00
abstract::Blunt and rotational head impacts due to vehicular collisions, falls and contact sports cause relative motion between the brain and skull. This increases the normal and shear stresses in the (skull/brain) interface region consisting of cerebrospinal fluid (CSF) and subarachnoid space (SAS) trabeculae. The relative mot...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840903064897
更新日期:2009-02-01 00:00:00
abstract::Cell-cell and cell-matrix adhesions are fundamental to numerous physiological processes, including angiogenesis, tumourigenesis, metastatic spreading and wound healing. We use cellular potts model to computationally predict the organisation of cells within a 3D matrix. The energy potentials regulating cell-cell (JCC) ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.792917
更新日期:2015-01-01 00:00:00
abstract::In electromagnetic dosimetry, anatomical human models are commonly obtained by segmentation of magnetic resonance imaging or computed tomography scans. In this paper, a human head model extracted from thermal infrared images is examined in terms of its applicability to specific absorption rate (SAR) calculations. Sinc...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.563738
更新日期:2011-07-01 00:00:00
abstract::Mutual information (MI)-based registration, which uses MI as the similarity measure, is a representative method in medical image registration. It has an excellent robustness and accuracy, but with the disadvantages of a large amount of calculation and a long processing time. In this paper, by computing the medical ima...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.557372
更新日期:2012-01-01 00:00:00
abstract::Computational models are increasingly being used to investigate the mechanical properties of cardiac tissue. While much insight has been gained from these studies, one important limitation associated with computational modeling arises when using in vivo images of the heart to generate the reference state of the model....
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2016.1183122
更新日期:2016-12-01 00:00:00
abstract::The objective of this investigation was to develop probabilistic finite element (FE) models of the anterior longitudinal ligament (ALL) and posterior longitudinal ligament (PLL) of the cervical spine that incorporate the natural variability of biological specimens. In addition to the model development, a rigorous vali...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2012.726353
更新日期:2014-01-01 00:00:00
abstract::In this review, we provide an overview of the simulation techniques employed for modelling the flow of red blood cells (RBCs) in blood plasma. The scope of this review omits the fluid modelling aspect while focusing on other key components in the RBC-plasma model such as (1) describing the RBC deformation with shell-b...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章,评审
doi:10.1080/10255842.2013.783574
更新日期:2015-01-01 00:00:00
abstract::The rate of bone loss is subject to considerable variation between individuals. With the 'mechanostat' model of Frost, genetic variations in bone mechanoresponsiveness are modelled by different mechanostat 'setpoints'--which may also change with age or disease. In this paper, the following setpoints are used: epsilonm...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840802136150
更新日期:2008-10-01 00:00:00
abstract::In this article, the problem of laminar, isothermal, incompressible and viscous flow in a rectangular domain bounded by two moving porous walls, which enable the fluid to enter or exit during successive expansions or contractions, is investigated. The governing non-linear equations and their associated boundary condit...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2010.497490
更新日期:2011-10-01 00:00:00
abstract::The phenotype expression in X-linked adrenoleukodystrophy is one of the most intriguing issues of the disease, because there is no general correlation between the type of ABCD1 gene mutation and the clinical phenotype. In this study, we use the cross-impact analysis to build a descriptively quantitative relationship b...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840903279974
更新日期:2010-06-01 00:00:00
abstract::This study is aimed at setting a method of experimental parameter estimation for large-deforming nonlinear viscoelastic continuous fibre-reinforced composite material model. Specifically, arterial tissue was investigated during experimental research and parameter estimation studies, due to medical, scientific and soci...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2012.666532
更新日期:2013-01-01 00:00:00
abstract::An appropriate method of application of the hip-joint force and stress analysis of the pelvic bone, in particular the acetabulum, is necessary to investigate the changes in load transfer due to implantation and to calculate the reference stimulus for bone remodelling simulations. The purpose of the study is to develop...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.843674
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Develop a finite element (FE) model of a skull to perform biomechanical studies of maxillary expansion using bone anchors (BA). MATERIALS AND METHODS:A skull model was developed and assigned material properties based on Hounsfield unit (HU) values of cone-beam computerized tomography (CBCT) images. A 3 mm di...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840601098098
更新日期:2007-04-01 00:00:00
abstract::The aim of this study was to investigate and present a new mapping method to describe muscle pain sensitivity based on the assessment of pressure pain threshold (PPT) over the trapezius muscle. PPT data were recorded from 36 points in 20 healthy males using a standardised grid. Points were clustered using the K-means ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840903446979
更新日期:2010-12-01 00:00:00
abstract::The aim of this study was to develop a generic musculoskeletal model of a healthy 10-year-old child and examine the effects of geometric scaling on the calculated values of lower-limb muscle forces during gait. Subject-specific musculoskeletal models of five healthy children were developed from in vivo MRI data, and t...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1817405
更新日期:2020-09-17 00:00:00
abstract::A novel, coarse-grained, single-framework 'Eulerian' model for blood flow in the microvascular circulation is presented and used to estimate the variations in flow properties that accrue from all of the following: (i) wall position variation, associated with the endothelial cells' (ECs) shape, (ii) glycocalyx layer (G...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.799146
更新日期:2015-01-01 00:00:00
abstract::The mechanical properties of soft biological tissues in general and early stage engineered tissues in particular limit the feasibility of conventional tensile tests for their mechanical characterisation. Furthermore, the most important mode in development of deep tissue injury (DTI) is compression. Therefore, an inver...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840701771768
更新日期:2008-10-01 00:00:00
abstract::Most of musculoskeletal models (MSKM) estimate the tibiofemoral joint reaction load at a single point or do not support large lower-limb ranges. This study aimed to adapt a generic MSKM that allows large knee and hip flexions to compute medial and lateral tibiofemoral contact forces (TFCF) during gait and squat tasks....
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1757662
更新日期:2020-08-01 00:00:00
abstract::Design optimization for cementless hip prosthesis signifies one of the key topics of research to improve its performances. However, majority of the studies have not considered the presence of uncertainties while it has been shown that a deterministic optimization leads to an unreliable design. In this paper, a multi-o...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1768247
更新日期:2020-09-01 00:00:00
abstract::Fretting and corrosion at the taper-head interface in total hip arthroplasty has been reported as a potential cause of early failure of the implant system. The finite element (FE) method can be used to study the mechanics at the taper junction that are difficult to assess experimentally. Taper mismatch is one of the f...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2019.1627524
更新日期:2019-10-01 00:00:00
abstract::Rupture of intracranial saccular aneurysms continues to result in significant morbidity and mortality. Although it has long been thought that biomechanical factors play key roles in the genesis, growth, and rupture of these lesions, few analysis have employed realistic descriptions of the geometries and material prope...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/01495739708936698
更新日期:1998-01-01 00:00:00
abstract::Finite element analysis provides a means of describing cellular mechanics in tissue, which can be useful in understanding and predicting physiological and pathological changes. Many prior studies have been limited to simulations of models containing single cells, which may not accurately describe the influence of mech...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2014.900545
更新日期:2015-01-01 00:00:00
abstract::The goal and clinical relevance of this work was the development of closed formulas that are correct and simple enough for a fast decision making by the orthodontist in the daily praxis. This paper performs a parametric three-dimensional finite element linear analysis on a maxillary central incisor with a root of para...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840290032126
更新日期:2002-04-01 00:00:00
abstract::The behavior of blood cells and vessel compliance significantly influence hemodynamic parameters, which are closely related to the development of aortic dissection. Here the two-phase non-Newtonian model and the fluid-structure interaction (FSI) method are coupled to simulate blood flow in a patient-specific dissected...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2019.1577398
更新日期:2019-05-01 00:00:00
abstract::The combination of computational methods with 3D printing allows for the control of scaffolds microstructure. Lately, triply periodic minimal surfaces (TPMS) have been used to design porosity-controlled scaffolds for bone tissue engineering (TE). The goal of this work was to assess the mechanical properties of TPMS Gy...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2019.1569638
更新日期:2019-05-01 00:00:00
abstract::Rupture prediction of abdominal aortic aneurysms (AAAs) remains a clinical challenge. Finite element analysis (FEA) may allow for improved identification for intervention timing, but the method needs further substantiation. In this study, experimental photoelastic method and finite element techniques were compared usi...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.574618
更新日期:2012-01-01 00:00:00