Abstract:
:Cardiac resynchronization therapy (CRT) threw lights on heart failure treatment, however, parts of patients showed nonresponse to CRT. Unfortunately, it lacks effective parameters to predict CRT non-response. In present study, we try to seek effective electro-echocardiographic predictors on CRT non-response. This is a retrospective study to review a total of 227 patients of dyssynchronous heart failure underwent CRT implantation. Logistic analysis was performed between CRT responders and CRT non-responders. The primary outcome was the occurrence of improved left ventricular ejection fraction 1 year after CRT implantation. We concluded that LVEDV > 255 mL (OR = 2.236; 95% CI, 1.016-4.923) rather than LVESV > 160 mL (OR = 1.18; 95% CI, 0.544-2.56) and TpTe/QTc > 0.203 (OR = 5.206; 95% CI, 1.89-14.34) significantly predicted CRT non-response. Oppositely, S wave > 5.7 cm/s (OR = 0.242; 95% CI, 0.089-0.657), E/A > 1 (OR = 0.211; 95% CI, 0.079-0.566), E'/A' > 1 (OR = 0.054; 95% CI, 0.017-0.172), CLBBB (OR = 0.141; 95% CI, 0.048-0.409), and QRS duration >160 ms (OR = 0.52; 95% CI, 0.305-0.922) surprisingly predicted low-probability of CRT non-response.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yu Z,Chen X,Han F,Qin S,Li M,Wu Y,Su Y,Ge Jdoi
10.1038/srep44009subject
Has Abstractpub_date
2017-03-10 00:00:00pages
44009issn
2045-2322pii
srep44009journal_volume
7pub_type
杂志文章abstract::More than 20 years after the first outbreaks, the phylogenetic picture of PRRSV is still incomplete and full of gaps, especially in regards of PRRSV 1. Due to the exceptional diversity observed at the eastern borders of Europe and the low number of available sequences from Central Eastern European countries, the autho...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26036-w
更新日期:2018-05-17 00:00:00
abstract::It is highly important to understand the heterogeneous wettability properties of porous media for enhanced oil recovery (EOR). However, wettability measurements are still challenging in directly investigating the wettability of porous media. In this paper, we propose a multidimensional nuclear magnetic resonance (NMR)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31803-w
更新日期:2018-09-07 00:00:00
abstract::The SLRP opticin (OPTC) has been demonstrated to be produced and degraded in osteoarthritic (OA) human cartilage. Here, we investigated the in vivo effect of OPTC deficiency in OA cartilage. OA was induced in 10-week-old Optc -/- and Optc +/+ mice. Ten weeks post-surgery, cartilage was processed for histology and immu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18047-w
更新日期:2018-01-11 00:00:00
abstract::Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap. Here, we evaluated the impact of sexual dimorphism and of the estrous cycle on muscle strength and running power of C57BL/6 mice. Like men, male mi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29050-0
更新日期:2018-07-16 00:00:00
abstract::Thymoquinone has been reported to exhibit antioxidant and anti-inflammatory effects. Inflammation plays an important role in pathogenesis of diabetic peripheral neuropathy. This study investigated the effects of TQ on proliferation and apoptosis of Schwann cells exposed to high glucose conditions and electrophysiologi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31656
更新日期:2016-08-22 00:00:00
abstract::Honeybee pupae morphology can be affected by a number of stressor, but in vivo investigation is difficult. A computed tomography (CT) technique was applied to visualize a comb's inner structure without damaging the brood. The CT scan was performed on a brood comb containing pupae developed from eggs laid by the queen ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46474-4
更新日期:2019-07-23 00:00:00
abstract::Glyoxalase pathway plays an important role in stress adaptation and many clinical disorders. The first enzyme of this pathway, glyoxalase I (GlxI), uses methylglyoxal as a substrate and requires either Ni(II)/Co(II) or Zn(II) for activity. Here we have investigated the origin of different metal ion specificities of Gl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03076
更新日期:2013-11-13 00:00:00
abstract::Driven diffusive systems have been a paradigm for modelling many physical, chemical, and biological transport processes. In the systems, spatial correlation plays an important role in the emergence of a variety of nonequilibrium phenomena and exhibits rich features such as pronounced oscillations. However, the lack of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19652
更新日期:2016-01-25 00:00:00
abstract::Chloroquine (CQ) is widely used as an anti-inflammatory therapeutic for rheumatic diseases. Although its modes of action on the innate immune system are well described, there is still insufficient knowledge about its direct effects on the adaptive immune system. Thus, we evaluated the influence of CQ on activation par...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42191
更新日期:2017-02-07 00:00:00
abstract::Nerve fibers are known to reside within malignant tumors and the greater the neuronal density the worse prognosis for the patient. Recent discoveries using tumor bearing animal models have eluded to the autonomic nervous system having a direct effect on tumor growth and metastasis. We report the first direct and chron...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71670-y
更新日期:2020-09-09 00:00:00
abstract::Bemisia tabaci is a cryptic whitefly-species complex that includes some of the most damaging pests and plant-virus vectors of a diverse range of food and fibre crops worldwide. We combine experimental evidence of: (i) differences in reproductive compatibility, (ii) hybrid verification using a specific nuclear DNA mark...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29305-w
更新日期:2018-07-18 00:00:00
abstract::During the infection process, the influenza fusion peptide (FP) inserts into the host membrane, playing a crucial role in the fusion process between the viral and host membranes. In this work we used a combination of simulation and experimental techniques to analyse the molecular details of this process, which are lar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28099
更新日期:2016-06-15 00:00:00
abstract::A novel marine strain representing efficient degradation ability toward brown algae was isolated, identified, and assigned to Bacillus weihaiensis Alg07. The alga-associated marine bacteria promote the nutrient cycle and perform important functions in the marine ecosystem. The de novo sequencing of the B. weihaiensis ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38248
更新日期:2016-11-30 00:00:00
abstract::Many species of chiton are known to deposit magnetite (Fe3O4) within the cusps of their heavily mineralized and ultrahard radular teeth. Recently, much attention has been paid to the ultrastructural design and superior mechanical properties of these radular teeth, providing a promising model for the development of nov...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37839-2
更新日期:2019-01-29 00:00:00
abstract::Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48339-2
更新日期:2019-09-10 00:00:00
abstract::Printable, wide band-gap chalcopyrite compound films (CuInGaS2, CIGS) were synthesized on transparent conducting oxide substrates. The wide band-gap and defective nature of the films reveal semi-transparent and bifacial properties that are beneficial for power generating window applications. Importantly, solar cell de...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04408
更新日期:2014-03-18 00:00:00
abstract::The aims of this study were to explore whether DNA methylation at INSR and IGF2 mediated the association of prenatal exposure to the Chinese great famine with adulthood waist circumference (WC) and BMI. A total of 235 subjects were selected into the present study from severely affected province and a neighbor province...
journal_title:Scientific reports
pub_type: 历史文章,杂志文章
doi:10.1038/s41598-020-69120-w
更新日期:2020-07-22 00:00:00
abstract::Great interest has been shown in mesenchymal stem cell (MSC) therapy in a wide variety of clinical domains. However, the therapeutic efficiency depends on the proliferation and migration of MSCs. Chemokine receptors are involved in regulating the proliferation and migration to the specific organs of MSCs in different ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18509-1
更新日期:2018-01-09 00:00:00
abstract::Microscopic swimming devices hold promise for radically new applications in lab-on-a-chip and microfluidic technology, diagnostics and drug delivery etc. In this paper, we demonstrate the experimental verification of a new class of autonomous ferromagnetic swimming devices, actuated and controlled solely by an oscilla...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44142
更新日期:2017-03-09 00:00:00
abstract::We propose an ultrathin metallic structure to produce frequency-selective spoof surface plasmon polaritons (SPPs) in the microwave and terahertz frequencies. Designed on a thin dielectric substrate, the ultrathin metallic structure is composed of two oppositely oriented single-side corrugated strips, which are coupled...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08165
更新日期:2015-02-02 00:00:00
abstract::The prevalence of patients on automated peritoneal dialysis (APD) is increasing worldwide and may be guided by clinical characteristics, financial issues and patient option. Whether socioeconomic factors at the patient level may influence the decision for the initial peritoneal dialysis (PD) modality is unknown. This ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05544-1
更新日期:2017-07-12 00:00:00
abstract::Melanosomes (melanin-bearing organelles) are common in the fossil record occurring as dense packs of globular microbodies. The organic component comprising the melanosome, melanin, is often preserved in fossils, allowing identification of the chemical nature of the constituent pigment. In present-day vertebrates, mela...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52318-y
更新日期:2019-11-04 00:00:00
abstract::NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to describe differences i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41672-6
更新日期:2019-03-26 00:00:00
abstract::In recent years, numerous methods have emerged for the synthesis of trifluoromethylated arenes based on the late-stage introduction of a trifluoromethyl group onto an aryl ring. In sharp comparison, the synthesis of trifluoromethylated arenes based on the pre-introduction of a trifluoromethyl group onto an "aromatic t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26957
更新日期:2016-06-01 00:00:00
abstract::The impact of obesity on health-related quality of life (HRQoL) in chronic kidney disease (CKD) population has not been elucidated, despite the impairment of HRQoL in the obese among general population. We hypothesized that the impact of obesity on HRQoL might be confounded by impaired renal function in CKD population...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59382-9
更新日期:2020-02-11 00:00:00
abstract::Large spin splitting at Rashba interface, giving rise to strong spin-momentum locking, is essential for efficient spin-to-charge conversion. Recently, a Cu/Bismuth oxide (Bi2O3) interface has been found to exhibit an efficient spin-to-charge conversion similar to a Ag/Bi interface with large Rashba spin splitting. How...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23787-4
更新日期:2018-04-03 00:00:00
abstract::Supercapacitors with aqueous electrolytes and nanostructured composite electrodes are attractive because of their high charging-discharging speed, long cycle life, low environmental impact and wide commercial affordability. However, the energy capacity of aqueous supercapacitors is limited by the electrochemical windo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09854
更新日期:2015-04-21 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-62901-3
更新日期:2020-04-20 00:00:00
abstract::Understanding the molecular mechanism by which epithelial mesenchymal transition (EMT)-mediated cancer metastasis and how microRNA (miRNA) regulates lung cancer progression via Twist1-activated EMT may provide potential therapeutic targets for cancer therapy. Here we found that miR-33a, an intronic miRNA located withi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13677
更新日期:2015-09-02 00:00:00
abstract::In recent years, high energy density polymer capacitors have attracted a lot of scientific interest due to their potential applications in advanced power systems and electronic devices. Here, core-shell structured TiO2@SrTiO3@polydamine nanowires (TiO2@SrTiO3@PDA NWs) were synthesized via a combination of surface conv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73884-6
更新日期:2020-10-13 00:00:00