Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages.

abstract：:We introduce the Precipitation Probability DISTribution (PPDIST) dataset, a collection of global high-resolution (0.1°) observation-based climatologies (1979-2018) of the occurrence and peak intensity of precipitation (P) at daily and 3-hourly time-scales. The climatologies were produced using neural networks trained ...

journal_title：Scientific data

authors： Beck HE,Westra S,Tan J,Pappenberger F,Huffman GJ,McVicar TR,Gründemann GJ,Vergopolan N,Fowler HJ,Lewis E,Verbist K,Wood EF

更新日期：2020-09-11 00:00:00

abstract：:Eicosanoids comprise a class of bioactive lipids derived from a unique group of essential fatty acids that mediate a variety of important physiological functions. Owing to the structural diversity of these lipids, their analysis in biological samples is often a major challenge. Advancements in mass spectrometric have ...

journal_title：Scientific data

authors： Sorgi CA,Peti APF,Petta T,Meirelles AFG,Fontanari C,Moraes LAB,Faccioli LH

更新日期：2018-08-21 00:00:00

abstract：:The COVID-19 pandemic has ignited interest in age-specific manifestations of infection but surprisingly little is known about relative severity of infectious disease between the extremes of age. In a systematic analysis we identified 142 datasets with information on severity of disease by age for 32 different infectio...

journal_title：Scientific data

authors： Glynn JR,Moss PAH

更新日期：2020-10-15 00:00:00

abstract：:The experimental dataset presented was collected in an 18 m long and 1 m wide laboratory flume. Low to high flood flows through an urbanized floodplain were modelled. The floodplain bed is rough, modelled with dense artificial grass. A square cylinder array, representing house models, was set on the rough bed. The cyl...

journal_title：Scientific data

authors： Oukacine M,Proust S,Larrarte F,Goutal N

更新日期：2021-01-11 00:00:00

abstract：:This article presents data derived from a 36 year-long uninterrupted observational study of amphibian populations living in the city and vicinity of Yekaterinburg, Russia. This area is inhabited by six amphibian species. Based on a degree of anthropogenic transformation, the urban territory is divided into five highly...

journal_title：Scientific data

authors： Vershinin VL,Vershinina SD,Berzin DL,Zmeeva DV,Kinev AV

更新日期：2015-05-12 00:00:00

abstract：:Animal muscles must maintain their function and structure while bearing substantial mechanical loads. How muscles withstand persistent mechanical strain is presently not well understood. Understanding the mechanisms by which tissues maintain their complex architecture is a key goal of cell biology. This dataset repres...

journal_title：Scientific data

authors： Perkins AD,Lee MJ,Tanentzapf G

更新日期：2014-03-11 00:00:00

abstract：:East Africa is a drought prone, food and water insecure region with a highly variable climate. This complexity makes rainfall estimation challenging, and this challenge is compounded by low rain gauge densities and inhomogeneous monitoring networks. The dearth of observations is particularly problematic over the past ...

journal_title：Scientific data

authors： Funk C,Nicholson SE,Landsfeld M,Klotter D,Peterson P,Harrison L

更新日期：2015-09-29 00:00:00

abstract：:The data record contains Material Intensity data for buildings (MI). MI coefficients are often used for different types of analysis of socio-economic systems and in particular for environmental assessments. Until now, MI values were compiled and reported ad-hoc with few cross-study comparisons. We extracted and conver...

journal_title：Scientific data

authors： Heeren N,Fishman T

更新日期：2019-04-09 00:00:00

abstract：:RAS genes are frequently mutated in cancer and have for decades eluded effective therapeutic attack. The National Cancer Institute's RAS Initiative has a focus on understanding pathways and discovering therapies for RAS-driven cancers. Part of these efforts is the generation of novel reagents to enable the quantificat...

journal_title：Scientific data

authors： Schoenherr RM,Huang D,Voytovich UJ,Ivey RG,Kennedy JJ,Saul RG,Colantonio S,Roberts RR,Knotts JG,Kaczmarczyk JA,Perry C,Hewitt SM,Bocik W,Whiteley GR,Hiltke T,Boja ES,Rodriguez H,Whiteaker JR,Paulovich AG

更新日期：2019-08-29 00:00:00

abstract：:Tardigrades are ubiquitous microscopic animals that play an important role in the study of metazoan phylogeny. Most terrestrial tardigrades can withstand extreme environments by entering an ametabolic desiccated state termed anhydrobiosis. Due to their small size and the non-axenic nature of laboratory cultures, molec...

journal_title：Scientific data

authors： Arakawa K,Yoshida Y,Tomita M

更新日期：2016-08-16 00:00:00

abstract：:Polyadenylation plays an important role in gene regulation, thus affecting a wide variety of biological processes. In the rice blast fungus Magnaporthe oryzae the cleavage factor I protein Rpb35 is required for pre-mRNA polyadenylation and fungal virulence. Here we present the bioinformatic approach and output data re...

journal_title：Scientific data

authors： Marconi M,Sesma A,Rodríguez-Romero JL,González MLR,Wilkinson MD

更新日期：2018-11-27 00:00:00

abstract：:Olympia oysters are found along the west coast of North America and as the only native oyster species in the region, receive considerable attention with regard to restoration and conservation. Knowledge of genetic structure of this species is essential for resource managers. Here we provide genetic data for three dist...

journal_title：Scientific data

authors： White SJ,Vadopalas B,Silliman K,Roberts SB

更新日期：2017-09-12 00:00:00

abstract：:Benthic fauna refers to all fauna that live in or on the seafloor, which researchers typically divide into size classes meiobenthos (32/64 µm-0.5/1 mm), macrobenthos (250 µm-1 cm), and megabenthos (>1 cm). Benthic fauna play important roles in bioturbation activity, mineralization of organic matter, and in marine food...

journal_title：Scientific data

authors： Stratmann T,van Oevelen D,Martínez Arbizu P,Wei CL,Liao JX,Cusson M,Scrosati RA,Archambault P,Snelgrove PVR,Ramey-Balci PA,Burd BJ,Kenchington E,Gilkinson K,Belley R,Soetaert K

更新日期：2020-06-29 00:00:00

abstract：:Social network analysis is an invaluable tool to understand the patterns, evolution, and consequences of sociality. Comparative studies over a range of social systems across multiple taxonomic groups are particularly valuable. Such studies however require quantitative social association or interaction data across mult...

journal_title：Scientific data

authors： Sah P,Méndez JD,Bansal S

更新日期：2019-04-29 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) differentiated into hepatocyte-like cells (HLCs) provide a defined and renewable source of cells for drug screening, toxicology and regenerative medicine. We previously reprogrammed human fetal foreskin fibroblast cells (HFF1) into iPSCs emp...

journal_title：Scientific data

authors： Wruck W,Adjaye J

更新日期：2018-03-13 00:00:00

abstract：:Fully-automated nuclear image segmentation is the prerequisite to ensure statistically significant, quantitative analyses of tissue preparations,applied in digital pathology or quantitative microscopy. The design of segmentation methods that work independently of the tissue type or preparation is complex, due to varia...

journal_title：Scientific data

authors： Kromp F,Bozsaky E,Rifatbegovic F,Fischer L,Ambros M,Berneder M,Weiss T,Lazic D,Dörr W,Hanbury A,Beiske K,Ambros PF,Ambros IM,Taschner-Mandl S

更新日期：2020-08-11 00:00:00

abstract：:With the aim to uncover the molecular pathways underlying the regulation of sleep, we recently assembled an extensive and comprehensive systems genetics dataset interrogating a genetic reference population of mice at the levels of the genome, the brain and liver transcriptomes, the plasma metabolome, and the sleep-wak...

journal_title：Scientific data

authors： Jan M,Gobet N,Diessler S,Franken P,Xenarios I

更新日期：2019-10-31 00:00:00

abstract：:Size-resolved aerosol samples were collected in Metro Manila between July 2018 and October 2019. Two Micro-Orifice Uniform Deposit Impactors (MOUDI) were deployed at Manila Observatory in Quezon City, Metro Manila with samples collected on a weekly basis for water-soluble speciation and mass quantification. Additional...

journal_title：Scientific data

authors： Stahl C,Cruz MT,Bañaga PA,Betito G,Braun RA,Aghdam MA,Cambaliza MO,Lorenzo GR,MacDonald AB,Pabroa PC,Yee JR,Simpas JB,Sorooshian A

更新日期：2020-04-29 00:00:00

abstract：:Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. In the last decade, the advent and continued development of molecular profiling technologies has enabled researchers to generate vast amount of 'omics' data, which together with integra...

journal_title：Scientific data

authors： Sirota M,Thomas CG,Liu R,Zuhl M,Banerjee P,Wong RJ,Quaintance CC,Leite R,Chubiz J,Anderson R,Chappell J,Kim M,Grobman W,Zhang G,Rokas A,England SK,Parry S,Shaw GM,Simpson JL,Thomson E,Butte AJ,March of Dimes Pre

更新日期：2018-11-06 00:00:00

abstract：:In angiogenesis with concurrent inflammation, many pathways are activated, some linked to VEGF and others largely VEGF-independent. Pathways involving inflammatory mediators, chemokines, and micro-RNAs may play important roles in maintaining a pro-angiogenic environment or mediating angiogenic regression. Here, we des...

journal_title：Scientific data

authors： Mukwaya A,Lindvall JM,Xeroudaki M,Peebo B,Ali Z,Lennikov A,Jensen LD,Lagali N

更新日期：2016-11-22 00:00:00

abstract：:The human HCC1806 cell line is frequently used as a preclinical model for triple negative breast cancer (TNBC). Given that dysregulated epigenetic mechanisms are involved in cancer pathogenesis, emerging therapeutic strategies target chromatin regulators, such as histone deacetylases. A comprehensive understanding of ...

journal_title：Scientific data

authors： Perreault AA,Sprunger DM,Venters BJ

更新日期：2019-03-05 00:00:00

abstract：:Chest radiography is an extremely powerful imaging modality, allowing for a detailed inspection of a patient's chest, but requires specialized training for proper interpretation. With the advent of high performance general purpose computer vision algorithms, the accurate automated analysis of chest radiographs is beco...

journal_title：Scientific data

authors： Johnson AEW,Pollard TJ,Berkowitz SJ,Greenbaum NR,Lungren MP,Deng CY,Mark RG,Horng S

更新日期：2019-12-12 00:00:00

abstract：:Cross sectional imaging is essential for the patient-specific planning and delivery of radiotherapy, a primary determinant of head and neck cancer outcomes. Due to challenges ensuring data quality and patient de-identification, publicly available datasets including diagnostic and radiation treatment planning imaging a...

journal_title：Scientific data

authors： Grossberg AJ,Mohamed ASR,Elhalawani H,Bennett WC,Smith KE,Nolan TS,Williams B,Chamchod S,Heukelom J,Kantor ME,Browne T,Hutcheson KA,Gunn GB,Garden AS,Morrison WH,Frank SJ,Rosenthal DI,Freymann JB,Fuller CD

更新日期：2018-09-04 00:00:00

abstract：:While tick-borne zoonoses, such as Lyme disease and tick-borne encephalitis, present an increasing global concern, knowledge of their vectors' distribution remains limited, especially for China. In this paper, we present the first comprehensive dataset of known tick species and their distributions in China, derived fr...

journal_title：Scientific data

authors： Zhang G,Zheng D,Tian Y,Li S

更新日期：2019-07-01 00:00:00

abstract：:We introduce and make openly accessible a comprehensive, multivariate time series (MVTS) dataset extracted from solar photospheric vector magnetograms in Spaceweather HMI Active Region Patch (SHARP) series. Our dataset also includes a cross-checked NOAA solar flare catalog that immediately facilitates solar flare pred...

journal_title：Scientific data

authors： Angryk RA,Martens PC,Aydin B,Kempton D,Mahajan SS,Basodi S,Ahmadzadeh A,Cai X,Filali Boubrahimi S,Hamdi SM,Schuh MA,Georgoulis MK

更新日期：2020-07-10 00:00:00

abstract：:Structural studies of challenging targets such as G protein-coupled receptors (GPCRs) have accelerated during the last several years due to the development of new approaches, including small-wedge and serial crystallography. Here, we describe the deposition of seven datasets consisting of X-ray diffraction images acqu...

journal_title：Scientific data

authors： Marin E,Luginina A,Gusach A,Kovalev K,Bukhdruker S,Khorn P,Polovinkin V,Lyapina E,Rogachev A,Gordeliy V,Mishin A,Cherezov V,Borshchevskiy V

更新日期：2020-11-12 00:00:00

abstract：:As basic data, the river networks and water resources zones (WRZ) are critical for planning, utilization, development, conservation and management of water resources. Currently, the river network and WRZ of world are most obtained based on digital elevation model data automatically, which are not accuracy enough, espe...

journal_title：Scientific data

authors： Yan D,Wang K,Qin T,Weng B,Wang H,Bi W,Li X,Li M,Lv Z,Liu F,He S,Ma J,Shen Z,Wang J,Bai H,Man Z,Sun C,Liu M,Shi X,Jing L,Sun R,Cao S,Hao C,Wang L,Pei M,Dorjsuren B,Gedefaw M,Girma A,Abiyu A

更新日期：2019-10-22 00:00:00

abstract：:The corneal endothelium maintains corneal transparency; consequently, damage to this endothelium by a number of pathological conditions results in severe vision loss. Publicly available expression databases of human tissues are useful for investigating the pathogenesis of diseases and for developing new therapeutic mo...

journal_title：Scientific data

authors： Tokuda Y,Okumura N,Komori Y,Hanada N,Tashiro K,Koizumi N,Nakano M

更新日期：2020-11-20 00:00:00

abstract：:We provide a detailed description of a gadoteridol-derivatized lysozyme (gadolinium lysozyme) two-colour serial femtosecond crystallography (SFX) dataset for multiple wavelength anomalous dispersion (MAD) structure determination. The data was collected at the Spring-8 Angstrom Compact free-electron LAser (SACLA) facil...

journal_title：Scientific data

authors： Gorel A,Motomura K,Fukuzawa H,Doak RB,Grünbein ML,Hilpert M,Inoue I,Kloos M,Nass Kovács G,Nango E,Nass K,Roome CM,Shoeman RL,Tanaka R,Tono K,Foucar L,Joti Y,Yabashi M,Iwata S,Ueda K,Barends TRM,Schlichting I

更新日期：2017-12-12 00:00:00

abstract：:The big-headed turtle, Platysternon megacephalum, as the sole member of the monotypic family Platysternidae, has a number of distinct characteristics including an extra-large head, long tail, flat carapace, and a preference for low water temperature environments. We performed whole genome sequencing, assembly, and gen...

journal_title：Scientific data

authors： Cao D,Wang M,Ge Y,Gong S

更新日期：2019-05-16 00:00:00