Abstract：
:To compare the performance of eight score systems (MELD, uMELD, MELD-Na. iMELD, UKELD, MELD-AS, CTP, and mCTP) in predicting the post-transplant mortality, we analyzed the data of 6,014 adult cirrhotic patients who underwent liver transplantation between January 2003 and December 2010 from the China Liver Transplant Registry database. In hepatitis B virus (HBV) group, MELD, uMELD and MELD-AS showed good predictive accuracies at 3-month mortality after liver transplantation; by comparison with other five models, MELD presented the best ability in predicting 3-month, 6-month and 1-year mortality, showing a significantly better predictive ability than UKELD and iMELD. In hepatitis C virus and Alcohol groups, the predictive ability did not differ significantly between MELD and other models. Patient survivals in different MELD categories were of statistically significant difference. Among patients with MELD score >35, a new prognostic model based on serum creatinine, need for hemodialysis and moderate ascites could identify the sickest one. In conclusion, MELD is superior to other score systems in predicting short-term post-transplant survival in patients with HBV-related liver disease. Among patients with MELD score >35, a new prognostic model can identify the sickest patients who should be excluded from waiting list to prevent wasteful transplantation.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ling Q,Dai H,Zhuang R,Shen T,Wang W,Xu X,Zheng Sdoi
10.1038/srep42253subject
Has Abstractpub_date
2017-02-13 00:00:00pages
42253issn
2045-2322pii
srep42253journal_volume
7pub_type
杂志文章abstract：:Au nanoparticles (AuNPs), which easily aggregate in organic thin film, are observed to well-disperse in chicken albumen thin films. The incorporated AuNPs is distributed uniformly inside the thin film and is as dense as 650 (particles/μm(3)). In addition, enhanced ultraviolet (UV) fluorescence centered at 350 nm is ob...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01505
更新日期：2013-01-01 00:00:00
abstract：:Ischemic stroke after radiofrequency catheter ablation (RFCA) in atrial fibrillation (AF) patients is a great challenge for electrophysiologists. We performed this retrospective study to evaluate clinical and echocardiographic characteristics associated with increased risk of ischemic stroke following RFCA. A total of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43566-z
更新日期：2019-05-07 00:00:00
abstract：:V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA) is an immune checkpoint that maintains peripheral T cell quiescence and inhibits anti-tumor immune responses. VISTA functions by dampening the interaction between myeloid cells and T cells, orthogonal to PD-1 and other checkpoints of the tumor-T cell...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71519-4
更新日期：2020-09-16 00:00:00
abstract：:The interplay between the quasi 1-dimensional CuO-chains and the 2-dimensional CuO2 planes of YBa(2)Cu(3)O(6+x) (YBCO) has been in focus for a long time. Although the CuO-chains are known to be important as charge reservoirs that enable superconductivity for a range of oxygen doping levels in YBCO, the understanding o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep07017
更新日期：2014-11-12 00:00:00
abstract：:Changes in immune and coagulation systems and possible viral spread through the blood-brain barrier have been described in SARS-CoV-2 infection. In this study, we evaluated the possible retinal involvement and ocular findings in severe COVID-19 pneumonia patients. A cross-sectional study was conducted on 46 patients a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74446-6
更新日期：2020-10-15 00:00:00
abstract：:We sought to investigate the prevalence, functional characteristics, and clinical significance of right ventricular (RV) involvement in patients with hypertrophic cardiomyopathy (HCM). A total of 256 patients with HCM who underwent both cardiac magnetic resonance (CMR) imaging and transthoracic echocardiography within...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78945-4
更新日期：2020-12-14 00:00:00
abstract：:Features from Electrovestibulography (EVestG) recordings have been used to classify and measure the severity of both persistent post-concussion syndrome (PCS) and major depressive disorder. Herein, we examined the effect of comorbid depression on the detection of persistent PCS using EVestG. To validate our previously...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-018-32808-1
更新日期：2018-09-27 00:00:00
abstract：:Vitamin D deficiency has been related with metabolic alterations in polycystic ovary syndrome (PCOS). As well, hyperactivation of adrenal axis can be programmed early in life and could be related later with PCOS development. Our aim was to establish the relationship between vitamin D and adrenal parameters with metabo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40653-z
更新日期：2019-03-08 00:00:00
abstract：:Copper (Cu), an essential nutrient, promotes wound healing, however, target of Cu action and underlying mechanisms remain elusive. Cu chaperone Antioxidant-1 (Atox1) in the cytosol supplies Cu to the secretory enzymes such as lysyl oxidase (LOX), while Atox1 in the nucleus functions as a Cu-dependent transcription fac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33783
更新日期：2016-09-26 00:00:00
abstract：:Listeria monocytogenes is well known for having the ability to cross the placental barrier, leading to fetal infections and abortion. However, the mechanisms leading to infectious abortion are poorly understood. In this study, we demonstrate that interferon γ-induced GTPase (IGTP) contributes to the invasion of L. mon...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08195
更新日期：2015-02-03 00:00:00
abstract：:To discuss the status of epidemiology of stroke in the Mongolian and Han population aged over 45 years and to understand the treatment and prevention of stroke. Data collected on stroke populations aged over 45 years in the six areas in Inner Mongolia were analyzed by using stratified multi-stage cluster sampling. The...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45710
更新日期：2017-04-04 00:00:00
abstract：:Lactose intolerance is a major concern driving the growth of lactose-free foods including lactose-free infant formula. It is unknown what the metabolic consequence is of consumption of a formula where lactose has been replaced with corn syrup solids (CSS). Here, a randomized double-blinded intervention study was condu...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-017-03975-4
更新日期：2017-06-16 00:00:00
abstract：:Elevated plasma homocysteine (Hcy) is suggested as an independent risk factor for stroke. We aimed to investigate the association of Hcy concentration with intracranial atherosclerosis (ICAS) and extracranial AS (ECAS) in hypertensive patients without stroke in Chinese population and to explore modified effect of meth...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-19125-9
更新日期：2018-01-12 00:00:00
abstract：:Transmission electron microscopy and related analytical techniques have been widely used to study the microstructure of different materials. However, few research works have been performed in the field of glasses, possibly due to the electron-beam irradiation damage. In this paper, we have developed a method based on ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17526
更新日期：2015-12-08 00:00:00
abstract：:Sludge bulking is a major problem that restricts the development of the activated sludge process. The microbial community responsible for sludge bulking varies depending on water quality and operational conditions. This study analysed the microbial community of bulking sludge in oxidation ditch with ultra-low sludge l...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50086-3
更新日期：2019-09-23 00:00:00
abstract：:Previous studies reported that boreal winter precipitation in southeastern China (SEC) tends to increase during El Niño. In this study, however, we find that most weak El Niño events are accompanied by below-normal precipitation in SEC, although strong El Niño events are accompanied by above-normal precipitation in SE...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53496-5
更新日期：2019-11-22 00:00:00
abstract：:New techniques for the field detection of inorganic improvised explosive devices (IEDs) are urgently developed. Although ion mobility spectrometry (IMS) has been proved to be the most effective method for screening organic explosives, it still faces a major challenge to detect inorganic explosives owing to their low v...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06631
更新日期：2014-10-16 00:00:00
abstract：:Tumor-associated immune response plays a critical role in cancer pathogenesis. This study evaluated clinical implications of T cell cytokines and regulatory T cells (Tregs) in HCC patients treated with TACE. Whole blood was obtained for analysis of T cell cytokines (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40078-8
更新日期：2019-03-01 00:00:00
abstract：:Tobacco hairy root (HR) cultures, which have been widely used for the heterologous production of target compounds, have an innate capacity to bioconvert exogenous t-resveratrol (t-R) into t-piceatannol (t-Pn) and t-pterostilbene (t-Pt). We established genetically engineered HR carrying the gene encoding stilbene synth...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18330-w
更新日期：2017-12-21 00:00:00
abstract：:A number of Bruton's tyrosine kinase (BTK) inhibitors are currently in development, yet it has been difficult to visualize BTK expression and pharmacological inhibition in vivo in real time. We synthesized a fluorescent, irreversible BTK binder based on the drug Ibrutinib and characterized its behavior in cells and in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04782
更新日期：2014-04-24 00:00:00
abstract：:In this study, we categorize the microbial community in mangrove sediment samples from four different locations within a vast mangrove system in Kerala, India. We compared this data to other samples taken from the other known mangrove data, a tropical rainforest, and ocean sediment. An examination of the microbial com...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09254-6
更新日期：2017-08-18 00:00:00
abstract：:Exosomes contain cell-specific collections of bioactive materials including proteins, lipids, and RNAs that are transported to recipient cells to exert their impacts. MicroRNAs (miRNAs) can function as tumor suppressor or oncogenic genes and miR-21 is one of the most frequently up-regulated miRNAs in solid tumors incl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65207-6
更新日期：2020-05-19 00:00:00
abstract：:Different types of protein-protein interactions make different protein-protein interface patterns. Different machine learning methods are suitable to deal with different types of data. Then, is it the same situation that different interface patterns are preferred for prediction by different machine learning methods? H...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16397-z
更新日期：2017-11-22 00:00:00
abstract：:Equine athletes have a pattern of exercise which is analogous to human athletes and the cardiovascular risks in both species are similar. Both species have a propensity for atrial fibrillation (AF), which is challenging to detect by ECG analysis when in paroxysmal form. We hypothesised that the proarrhythmic backgroun...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63343-7
更新日期：2020-04-22 00:00:00
abstract：:This study investigated lead concentrations in the hairs of radiographers working in the radiological departments of general hospitals that used lead shielding for radiation protection. We collected scalp hair samples from 32 radiographers working in four radiology departments with lead shielding and 18 administration...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80721-3
更新日期：2021-01-08 00:00:00
abstract：:Submesoscale interleaving layers are caused by lateral intrusions of dissimilar water masses in frontal zones, which are significant processes in shaping physical, biogeochemical, and ecological parameters in the ocean. Possible interleaving layers were sometimes observed by ship-based conductivity-temperature-depth (...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47912-z
更新日期：2019-08-06 00:00:00
abstract：:Two-dimensional (2D) transition-metal dichalcogenides (TMDs), most notably, MoS2 and WS2, have attracted significant attention due to their sizable and direct bandgap characteristics. Although several interesting MoS2 and WS2-based optoelectronic devices have been reported, their processability and reproducibility are...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13783
更新日期：2015-09-08 00:00:00
abstract：:Bacterial pneumonia is a major cause of acute lung injury and acute respiratory distress syndrome, characterized by alveolar barrier disruption. NLRP3 is best known for its ability to form inflammasomes and to regulate IL-1β and IL-18 production in myeloid cells. Here we show that NLRP3 protects the integrity of the a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30943
更新日期：2016-08-01 00:00:00
abstract：:The mechanism of droplet drying is a widely concerned fundamental issue since controlling the deposition morphology of droplet has significant influence on printing, biology pattern, self-assembling and other solution-based devices fabrication. Here we reveal a striking different kinetics-controlled deposition regime ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24628
更新日期：2016-04-19 00:00:00
abstract：:The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden on human health because of ZIKV's neurotropic effects in the course of fetal development. Vaccine candidates against ZIKV are coming online, but immunological tools to study anti-ZIKV responses in preclinical models, particular...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00193-w
更新日期：2017-03-21 00:00:00
