Noninvasive prenatal diagnosis for single gene disorders.

abstract：PURPOSE OF REVIEW:To review current available literature on the relationship between fibroids and infertility with particular emphasis on the benefits of myomectomy. Pregnancy complications related to the presence of these lesions and to their removal are also addressed. RECENT FINDINGS:There is a biological plausibil...

journal_title：Current opinion in obstetrics & gynecology

authors： Somigliana E,Vercellini P,Benaglia L,Abbiati A,Barbara G,Fedele L

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current role of radiation therapy and specific types of radiation therapy used in the management of early stage, locoregionally advanced, and metastatic breast cancer. RECENT FINDINGS:The role of radiation therapy in the management of breast cancer has not changed in recent decades, h...

journal_title：Current opinion in obstetrics & gynecology

authors： McCloskey SA,Lee SP,Steinberg ML

更新日期：2011-02-01 00:00:00

abstract：:Studies published in the past year have attempted to model the pathophysiology of the twin-twin transfusion syndrome and also to establish the minimal diagnostic criteria for the condition. Many papers focused on treatment regimens and their sequelae. Aggressive treatment with serial amnioreduction continues to predom...

journal_title：Current opinion in obstetrics & gynecology

authors： Filkins KA,Beverly SE

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevention of breast, ovarian and endometrial cancer frequently involves hormonal or surgical interventions. Each of these may have noncancerous sequelae and can affect quality of life in women with hereditary cancer syndromes. The purpose of this review is to discuss the medical management of hor...

journal_title：Current opinion in obstetrics & gynecology

authors： Chapman JS,Jacoby V,Chen LM

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the available data regarding the value of oral contraceptive pill addition in ovarian stimulation schemes used for in-vitro fertilization. RECENT FINDINGS:In agonists cycles, a decreased incidence of ovarian cyst formation is expected in patients pretreated with the oral contraceptive pi...

journal_title：Current opinion in obstetrics & gynecology

authors： Kolibianakis EM,Venetis CA,Tarlatzis BC

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical utility of sperm DNA fragmentation tests needs to be revisited in light of increasing evidence of detrimental effect of sperm DNA damage on reproductive outcomes. RECENT FINDINGS:Current evidence supports the association between high sperm DNA fragmentation and poor outcomes with regards...

journal_title：Current opinion in obstetrics & gynecology

authors： Agarwal A,Cho CL,Esteves SC

更新日期：2016-06-01 00:00:00

abstract：:Immune based therapies for ovarian carcinoma continue to evolve. The current status of antibody, antibody conjugates, cytokine, cellular, and vaccine based immunotherapy is reviewed. Novel gene transfer strategies that will play an increasing important role in the evolution of immunotherapy are also discussed. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Vanderkwaak TJ,Alvarez RD

更新日期：1999-02-01 00:00:00

abstract：:Voiding disorders are frequently associated with urinary incontinence and other lower urinary tract dysfunction in women, but the cause of these disorders is not well understood and treatment options are limited. Little has changed in the treatment and evaluation of voiding disorders. New approaches to the study of de...

journal_title：Current opinion in obstetrics & gynecology

authors： Stevenson KR

更新日期：1996-10-01 00:00:00

abstract：:The battle against the epidemic of sexually transmitted infections continues but the clinician has new diagnostic and therapeutic weapons. This manuscript reviews new technologies, as well as novel applications of newer methodologies, such as utilization of amplified DNA techniques for urine specimens or patient-colle...

journal_title：Current opinion in obstetrics & gynecology

authors： Biro FM

更新日期：1999-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The management of locally advanced breast cancer requires a combined-modality treatment approach involving surgery, radiotherapy and systemic therapy. In this paper, we review clinical and experimental studies in order to evaluate how basic and clinical research in locally advanced breast cancer has p...

journal_title：Current opinion in obstetrics & gynecology

authors： Barni S,Mandalà M

更新日期：2006-02-01 00:00:00

abstract：:Human papillomavirus-related anogenital neoplasia is an active area of basic and clinical research. The research topics are broad based, but mostly are focused on delineating the clinical utility of human papillomavirus testing, the natural history of human papillomavirus infections and associated premalignancies, cha...

journal_title：Current opinion in obstetrics & gynecology

authors： Duggan MA

更新日期：1996-02-01 00:00:00

abstract：:Human embryo cryopreservation is now a fully established adjunct to assisted reproduction, with thawed embryos implanting at a rate approaching that of fresh embryos. As with fresh embryos, the quality of frozen-thawed embryos is affected by patient age at the time of oocyte retrieval, and by culture conditions. Ovari...

journal_title：Current opinion in obstetrics & gynecology

authors： Tucker MJ,Morton PC,Sweitzer CL,Wright G

更新日期：1995-06-01 00:00:00

abstract：:This review concentrates on the structural and functional aspects of lesions of the female genital tract that cause infertility, including cervical changes after treatment for neoplasia, uterine malformations, leiomyoma, endometrial aberrations, infection-related tubal lesions, ovarian disorders (oocyte defects, prema...

journal_title：Current opinion in obstetrics & gynecology

authors： Honoré LH

更新日期：1997-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been associated with a wide range of human disease states and the global epidemic, particularly in reproductive aged women, has led to a focus on this complex hormones role in human reproduction. Indeed vitamin D receptors are found throughout the reproductive tract in the ova...

journal_title：Current opinion in obstetrics & gynecology

authors： Franasiak JM,Lara EE,Pellicer A

更新日期：2017-08-01 00:00:00

abstract：:Neuromodulation is one option for the management of a wide variety of lower urinary tract disorders, including non-neuropathic and neuropathic bladder dysfunctions. The mechanisms of action of the reported techniques remain unclear; urodynamic changes are minimal, but symptomatic improvements are common. Although the ...

journal_title：Current opinion in obstetrics & gynecology

authors： Hasan ST,Neal DE

更新日期：1998-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lazarin GA,Goldberg JD

更新日期：2016-04-01 00:00:00

abstract：:Various malignant neoplasms, either primary or secondary, can affect the vagina. The most common primary malignant tumors of the vagina are squamous cell cancers; however, they are among the most uncommon of all primary gynecologic cancers. Vaginal intraepithelial neoplasia is being diagnosed with increasing frequency...

journal_title：Current opinion in obstetrics & gynecology

authors： Benedet JL

更新日期：1991-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights the complexity of caring for gynecologic patients who refuse blood transfusion and discusses the importance of early, targeted perioperative and intraoperative medical optimization. We review alternative interventions and the importance of medical management to minimize blood lo...

journal_title：Current opinion in obstetrics & gynecology

authors： Han ES,Arora C,Hur HC,Advincula AP,Kim JHJ

更新日期：2019-08-01 00:00:00

abstract：:This review explores the recent experience with, and the basis for, the use of selective estrogen receptor modulators to treat and prevent breast cancer. As new agents are unveiled, they will continue to be tested against tamoxifen. A number of new selective estrogen receptor modulators are in clinical development in ...

journal_title：Current opinion in obstetrics & gynecology

authors： Bentrem DJ,Jordan VC

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective intrauterine growth restriction (sIUGR) in twin pregnancies presents a complex management problem for the fetal medicine specialist. This review summarizes what is currently known about sIUGR pathophysiology, particularly in monochorionic pregnancies and looks at the results of early trials ...

journal_title：Current opinion in obstetrics & gynecology

authors： Townsend R,Khalil A

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutics targeting the ErbB protein family receptors have not always yielded favorable or successful results in present cancer therapy. This review discusses the possibility of the clinical adaptation of targeting against heparin-binding epidermal growth factor-like growth factor (HB-EGF), one of ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tsujioka H,Yotsumoto F,Hikita S,Ueda T,Kuroki M,Miyamoto S

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:With the recent advancements in reproductive medicine, many infertile couples now have the opportunity to conceive their own biological children. Although some medication protocols, such as clomiphene citrate, have been utilized for decades, other treatment modalities have evolved over the recent year...

journal_title：Current opinion in obstetrics & gynecology

authors： Torrealday S

更新日期：2014-06-01 00:00:00

abstract：:Few randomized studies have addressed the best choice of adjuvant radiation therapy after surgery for stage I endometrial cancer. Although whole pelvic radiation decreases the incidence of pelvic and vaginal cancer recurrence, there is no convincing evidence that it improves survival in women who have been completely ...

journal_title：Current opinion in obstetrics & gynecology

authors： Naumann RW

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances in oocyte and embryo cryopreservation techniques and outcomes. RECENT FINDINGS:Vitrification is gradually replacing slow freezing due to a better survival rate after thawing. Most units use vitrification for both oocyte and blastocyst cryopreservation, as these two biolog...

journal_title：Current opinion in obstetrics & gynecology

authors： Herrero L,Martínez M,Garcia-Velasco JA

更新日期：2011-08-01 00:00:00

abstract：:Urinary incontinence remains a common problem that adversely affects the quality of life of millions of women. In detrusor instability, treatment measures often lack efficacy or are accompanied by unacceptable side effects. In this review, standard treatments are discussed, together with recent pharmacologic advances ...

journal_title：Current opinion in obstetrics & gynecology

authors： Wise B,Cardozo L

更新日期：1991-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The increased risk of infertility in men with varicocele is well established. Varicocelectomy has been shown to improve semen parameters and increase pregnancy rates. Yet varicocele pathophysiology is poorly understood and potential implications for testosterone production are less clear. Evidence sug...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanrikut C,McQuaid JW,Goldstein M

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Much attention has been paid to the role of immunology in reproductive success or failure. Every step in the establishment of normal pregnancy has been implicated as a possible site of immune-mediated reproductive failure. The widespread testing of antiphospholipid, antinuclear, antithyroid, and antis...

journal_title：Current opinion in obstetrics & gynecology

authors： Kallen CB,Arici A

更新日期：2003-06-01 00:00:00

abstract：:The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vas...

journal_title：Current opinion in obstetrics & gynecology

authors： Lebovic DI,Mueller MD,Taylor RN

更新日期：1999-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Maternal mental health disorders, including anxiety and depression, are one of the most common obstetric complications, presenting in pregnancy and postpartum. RECENT FINDINGS:Maternal mental health disorders are associated with adverse maternal and neonatal outcomes. Screening women in pregnancy and...

journal_title：Current opinion in obstetrics & gynecology

authors： Yeaton-Massey A,Herrero T

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the epidemiology of thromboembolism in pregnancy and describe strategies to prevent and treat it. RECENT FINDINGS:The main reason for the increased risk of thrombosis in pregnancy is hypercoagulability. Other risk factors include a history of thrombosis, inh...

journal_title：Current opinion in obstetrics & gynecology

authors： James AH

更新日期：2008-12-01 00:00:00