Locally advanced breast cancer.

abstract：PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lazarin GA,Goldberg JD

更新日期：2016-04-01 00:00:00

abstract：:Neuromodulation is one option for the management of a wide variety of lower urinary tract disorders, including non-neuropathic and neuropathic bladder dysfunctions. The mechanisms of action of the reported techniques remain unclear; urodynamic changes are minimal, but symptomatic improvements are common. Although the ...

journal_title：Current opinion in obstetrics & gynecology

authors： Hasan ST,Neal DE

更新日期：1998-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Amidst the worldwide coronavirus disease 2019 pandemic, a new medical landscape revolving around telemedicine has arisen. The purpose of this review is to describe and analyze current urogynecologic guidelines for optimizing usage of telemedicine when treating women with pelvic floor disorders. RECEN...

journal_title：Current opinion in obstetrics & gynecology

authors： Serna-Gallegos T,Ninivaggio CS

更新日期：2020-12-01 00:00:00

abstract：:Ultrasound prenatal diagnosis of structural anomalies has become almost a separate branch of obstetrics. The advantages of performing ultrasound in pregnancies at high risk for fetal structural anomalies are clear. Patients and the news media have placed ever-increasing expectations on persons performing diagnostic ul...

journal_title：Current opinion in obstetrics & gynecology

authors： Gomez KJ,Copel JA

更新日期：1993-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review updated information on the influence of endometrial scratching on IVF. RECENT FINDINGS:Endometrial receptivity remains an important rate-limiting step affecting the success of IVF. The current evidence on the effect of endometrial scratching on IVF ranges from marked improvement, no differe...

journal_title：Current opinion in obstetrics & gynecology

authors： Ko JK,Ng EH

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article provides an overview of the molecular mechanisms underlying adolescent endometriosis and advances in both medical and surgical management. RECENT FINDINGS:Molecular and cellular features of endometriotic lesions differ from eutopic endometrium. There is altered estrogen-mediated c...

journal_title：Current opinion in obstetrics & gynecology

authors： Mama ST

更新日期：2018-10-01 00:00:00

abstract：:Infertile couples who seek medical advice have one single hope: to have one or more children. Therefore, pregnancy rates per cycle of any assisted reproductive technique that include early miscarriages and ectopic pregnancies are of little interest to them. They want to know their chances of having a baby. When counse...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanbo T,Abyholm T

更新日期：1996-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current consensus regarding the modern management of ovarian endometriosis and summarize the recent evidence that led to a shift in the management recommendations. RECENT FINDINGS:The vast majority of the recent studies demonstrate an adverse effect of surgery on ovarian reserve marke...

journal_title：Current opinion in obstetrics & gynecology

authors： Psaroudakis D,Hirsch M,Davis C

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Venous thromboembolism is the leading cause of maternal death in the UK. Thrombophilia underlies many thrombotic disorders in pregnancy. The high prevalence of thrombophilic defects in the population, the association of defects with venous thromboembolism and the special considerations for management ...

journal_title：Current opinion in obstetrics & gynecology

authors： Robertson L,Greer I

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been associated with a wide range of human disease states and the global epidemic, particularly in reproductive aged women, has led to a focus on this complex hormones role in human reproduction. Indeed vitamin D receptors are found throughout the reproductive tract in the ova...

journal_title：Current opinion in obstetrics & gynecology

authors： Franasiak JM,Lara EE,Pellicer A

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent literature on medical accuracy, program effectiveness, and ethical concerns related to abstinence-only policies for adolescent sexuality education. RECENT FINDINGS:The federal government invests over 175 million dollars annually in 'abstinence-only-until-marriage' programs. These pro...

journal_title：Current opinion in obstetrics & gynecology

authors： Ott MA,Santelli JS

更新日期：2007-10-01 00:00:00

abstract：:Human papillomavirus-related anogenital neoplasia is an active area of basic and clinical research. The research topics are broad based, but mostly are focused on delineating the clinical utility of human papillomavirus testing, the natural history of human papillomavirus infections and associated premalignancies, cha...

journal_title：Current opinion in obstetrics & gynecology

authors： Duggan MA

更新日期：1996-02-01 00:00:00

abstract：:Minimally invasive surgery enables the avoidance of, preparation for, participation in, and treatment of complications following assisted reproductive technology (ART). The major recent changes are, the development of surgical techniques to diagnose and treat intrafallopian tubal abnormalities; the use of operative en...

journal_title：Current opinion in obstetrics & gynecology

authors： Wood C

更新日期：1994-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The recovery of immature oocytes followed by in-vitro maturation (IVM) and in-vitro fertilization is an attractive alternative to conventional in-vitro fertilization treatment in which controlled ovarian stimulation with gonadotropins is used to increase the number of available oocytes and embryos. Si...

journal_title：Current opinion in obstetrics & gynecology

authors： Chian RC,Lim JH,Tan SL

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article will review recent changes in the standard of care for olaparib, niraparib, and rucaparib, as well as ongoing trials evaluating this class of drugs in combination with antiangiogenic agents and PD-1/PD-L1 inhibitors. RECENT FINDINGS:Niraparib received FDA approval for use in patients wit...

journal_title：Current opinion in obstetrics & gynecology

authors： Washington CR,Moore KN

更新日期：2021-02-01 00:00:00

abstract：:Early ectopic pregnancy screening using vaginal ultrasonographic technology together with measurement of beta human chorionic gonadotropin (beta-hCG) and human chorionic somatomammotropin is possible within the first 2 weeks of the missing menses, prior to the appearance of symptoms. This article summarizes the main a...

journal_title：Current opinion in obstetrics & gynecology

authors： Mettler L

更新日期：1991-06-01 00:00:00

abstract：:Urinary tract infections (UTIs) are still one of the most common bacterial infections in pregnant and non-pregnant women. It is estimated that about 10-20% of all women suffer from a UTI at some point in life. The presence of UTI is defined as the existence of urinary symptoms such as frequency of urination and dysuri...

journal_title：Current opinion in obstetrics & gynecology

authors： Weissenbacher ER,Reisenberger K

更新日期：1993-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The management of benign ovarian lesions in girls is currently a controversial topic in the pediatric surgical literature. The purpose of this review is to highlight the epidemiology of benign ovarian masses, outline preoperative risk stratification strategies, review the indications and importance of...

journal_title：Current opinion in obstetrics & gynecology

authors： Gonzalez DO,Minneci PC,Deans KJ

更新日期：2017-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Examine recent evidence of randomized controlled trials and meta-analyses regarding the effect of maternal vitamin D status and supplementation over obstetrical and offspring outcomes. RECENT FINDINGS:Maternal serum 25-hydroxyvitamin [25(OH)D] progressively declines during pregnancy because of fetal ...

journal_title：Current opinion in obstetrics & gynecology

authors： Pérez-López FR,Pilz S,Chedraui P

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Immune checkpoint blockade (ICB) is a promising area of cancer therapeutic research. Therapies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) mechanism of tumor immune evasion have resulted in durable responses in many difficult-to-treat tumor types. While these...

journal_title：Current opinion in obstetrics & gynecology

authors： Chin CD,Fares CM,Konecny GE,Rao J

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We present an update on amenorrhea in adolescent girls and young women. Amenorrhea may herald the onset of estrogen deficiency, which can adversely affect peak bone mass and ultimate risk of osteoporosis. RECENT FINDINGS:Adolescence is a critical period for bone accretion. Important modifiable factor...

journal_title：Current opinion in obstetrics & gynecology

authors： Gordon CM,Nelson LM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to summarize recently published clinical and animal-based studies of antenatal corticosteroids, describe current recommendations for practice, and suggest priority areas for future research. RECENT FINDINGS:A single course of antenatal corticosteroids is known to improv...

journal_title：Current opinion in obstetrics & gynecology

authors： Newnham JP,Moss TJ,Nitsos I,Sloboda DM

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Thyroid disorders are common in pregnancy and affect maternal and fetal outcome. RECENT FINDINGS:The reference values for normal thyroid function during first and second trimester had been re-evaluated recently. Hypothyroxinemia affects the neuropsychological development of the child. Maternal thyroi...

journal_title：Current opinion in obstetrics & gynecology

authors： Gärtner R

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevention of breast, ovarian and endometrial cancer frequently involves hormonal or surgical interventions. Each of these may have noncancerous sequelae and can affect quality of life in women with hereditary cancer syndromes. The purpose of this review is to discuss the medical management of hor...

journal_title：Current opinion in obstetrics & gynecology

authors： Chapman JS,Jacoby V,Chen LM

更新日期：2015-02-01 00:00:00

abstract：:This review explores some of the implications for a balanced approach to the ethics of maternal participation in clinical research, from the perspective of the fetus as a patient, which is a central concept in obstetric ethics. The review therefore begins with an account of this topic, followed by an examination of so...

journal_title：Current opinion in obstetrics & gynecology

authors： Chervenak FA,McCullough LB

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Many minimally invasive techniques have recently been introduced for the management of uterine fibroids. The purpose of this review is to analyse recent data for techniques that are used to manage uterine fibroids. RECENT FINDINGS:Laparoscopic myomectomy has provided a minimally invasive alternative ...

journal_title：Current opinion in obstetrics & gynecology

authors： Falcone T,Bedaiwy MA

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize results from the Women's Health Initiative trial and other recent randomized placebo-controlled trials of hormone replacement therapy, which fundamentally changed our understanding of its risks and benefits. RECENT FINDINGS:The Women's Health Initiative study for the first time provided ...

journal_title：Current opinion in obstetrics & gynecology

authors： Kocjan T,Prelevic GM

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Benefit of micronutrient supplementation on female fertility. RECENT FINDINGS:Reports of randomized trials are rare. Most studies are focused on multivitamin supplementations. For some micronutrients, a positive impact on fertility could be shown. This article reviews the available clinical studies a...

journal_title：Current opinion in obstetrics & gynecology

authors： Buhling KJ,Grajecki D

更新日期：2013-06-01 00:00:00

abstract：:Approximately 2-3% of cervical smears will be reported as showing low-grade changes. Many of these smears are in fact associated with high-grade cervical intraepithelial neoplasia requiring treatment, but a significant number will be associated with an absence of cervical intraepithelial neoplasia, where surveillance ...

journal_title：Current opinion in obstetrics & gynecology

authors： Cruickshank ME,Kitchener HC

更新日期：1995-02-01 00:00:00

abstract：:Studies published in the past year have attempted to model the pathophysiology of the twin-twin transfusion syndrome and also to establish the minimal diagnostic criteria for the condition. Many papers focused on treatment regimens and their sequelae. Aggressive treatment with serial amnioreduction continues to predom...

journal_title：Current opinion in obstetrics & gynecology

authors： Filkins KA,Beverly SE

更新日期：1998-12-01 00:00:00