Obstetric and perinatal outcome in pregnancies after assisted reproduction.

abstract：PURPOSE OF REVIEW:To highlight relevant strategies to overcome poly(ADP-ribose) polymerase (PARP) inhibitor resistance and present key clinical trials. RECENT FINDINGS:The use of PARP inhibition (PARPi) for frontline maintenance offers substantial clinical benefit in patients with homologous recombination-deficient tu...

journal_title：Current opinion in obstetrics & gynecology

authors： Hinchcliff E,Chelariu-Raicu A,Westin SN

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Sex trafficking of adolescents and young adults is both a human rights violation and a public health problem, globally and in the United States. Healthcare providers, including obstetricians and gynecologists, interact with victims, often while they remain under their traffickers' control, but because...

journal_title：Current opinion in obstetrics & gynecology

authors： Chaffee T,English A

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:More than 50% of all gynecologic cancers can be classified as rare tumors (defined as an incidence of <6 per 100 000) and as such represent a major challenge for clinicians. RECENT FINDINGS:The rapidly increasing number of targeted therapies provides a unique opportunity to improve treatment options ...

journal_title：Current opinion in obstetrics & gynecology

authors： Ray-Coquard I,Pujade-Lauraine E,Ledermann JA

更新日期：2015-02-01 00:00:00

abstract：:This review explores the recent experience with, and the basis for, the use of selective estrogen receptor modulators to treat and prevent breast cancer. As new agents are unveiled, they will continue to be tested against tamoxifen. A number of new selective estrogen receptor modulators are in clinical development in ...

journal_title：Current opinion in obstetrics & gynecology

authors： Bentrem DJ,Jordan VC

更新日期：2002-02-01 00:00:00

abstract：:Immune based therapies for ovarian carcinoma continue to evolve. The current status of antibody, antibody conjugates, cytokine, cellular, and vaccine based immunotherapy is reviewed. Novel gene transfer strategies that will play an increasing important role in the evolution of immunotherapy are also discussed. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Vanderkwaak TJ,Alvarez RD

更新日期：1999-02-01 00:00:00

abstract：:Selective oestrogen receptor modulators are a range of compounds which mimic some, but not all, agonist actions of oestrogen in different tissues. They were developed with the aim of maximizing the benefits of oestrogen-like drugs in a number of important conditions whilst reducing adverse side-effects. The molecular ...

journal_title：Current opinion in obstetrics & gynecology

authors： Baynes KC,Compston JE

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Hysteroscopic myomectomy was a revolution for surgical treatment of symptomatic submucosal myoma. RECENT FINDINGS:A new International Federation of Gynecology and Obstetrics classification for myoma was recently described. Type 0, 1 and 2 are submucosal like in the European Society for Human Reproduc...

journal_title：Current opinion in obstetrics & gynecology

authors： Capmas P,Levaillant JM,Fernandez H

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose is to review current recommendations for the evaluation and management of delayed puberty in the female patient. RECENT FINDINGS:Kisspeptin activation has emerged as an important factor for initiation of pubertal development. Causes of delayed puberty can be considered in four main catego...

journal_title：Current opinion in obstetrics & gynecology

authors： Trotman GE

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The increased risk of infertility in men with varicocele is well established. Varicocelectomy has been shown to improve semen parameters and increase pregnancy rates. Yet varicocele pathophysiology is poorly understood and potential implications for testosterone production are less clear. Evidence sug...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanrikut C,McQuaid JW,Goldstein M

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence-based women's healthcare is underpinned by systematic reviews and guidelines. Generating an evidence synthesis to support guidance for clinical practice is a time-consuming and labour-intensive activity that delays transfer of research into practice. Artificial intelligence has the potential ...

journal_title：Current opinion in obstetrics & gynecology

authors： Amezcua-Prieto C,Fernández-Luna JM,Huete-Guadix JF,Bueno-Cavanillas A,Khan KS

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Common and important psychosomatic disorders in pregnancy reviewed here include perinatal depression, posttraumatic stress disorders, anxiety disorders, eating disorders, and postpartum psychosis. RECENT FINDINGS:Research has focused on antenatal depression as postpartum depression often has onset pr...

journal_title：Current opinion in obstetrics & gynecology

authors： Tam WH,Chung T

更新日期：2007-04-01 00:00:00

abstract：:Magnetic resonance imaging represents a new method of imaging the pelvic viscera and pelvic floor musculature. Rapid sequences allow us to perform magnetic resonance imaging dynamically during straining or pelvic floor contraction, which can elegantly demonstrate the patterns of pelvic floor prolapse. The technique is...

journal_title：Current opinion in obstetrics & gynecology

authors： Steiner RA,Healy JC

更新日期：1998-08-01 00:00:00

abstract：:The surgical management of hydrosalpinges is a controversial subject. Chronic pathology of the fallopian tube with distal obstruction leads to the formation of a hydrosalpinx, and is associated with very poor pregnancy rates after surgery. In these cases, in-vitro fertilization has proved to be a much better alternati...

journal_title：Current opinion in obstetrics & gynecology

authors： Mansour R,Aboulghar M,Serour GI

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The study of embryonic development through conventional microscopy has contributed significantly to the success of IVF. However, clinical pregnancy rates per transfer remain as low as 30% according to the latest records of European society if human reproduction and society if assisted reproduction. Co...

journal_title：Current opinion in obstetrics & gynecology

authors： Basile N,Elkhatib I,Meseguer M

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the techniques recently tested in both animal models and humans to provide a state-of-the-art on adult stem cell ovarian transplant to achieve ovarian rejuvenation in patients with diminished ovarian reserves. RECENT FINDINGS:As the firsts reports of spontaneous pregnancies achieved after b...

journal_title：Current opinion in obstetrics & gynecology

authors： Herraiz S,Pellicer N,Romeu M,Pellicer A

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Endometriosis is a frequent gynaecological disorder in young women. Colorectal endometriosis accounts for about 90% of all intestinal locations. The effectiveness of medical therapies is poor, and surgery, including colorectal resection, is therefore often required. Since the first description of lapa...

journal_title：Current opinion in obstetrics & gynecology

authors： Daraï E,Bazot M,Rouzier R,Houry S,Dubernard G

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Laparoscopy is the gold standard for the diagnosis of endometriosis but the need for visual evidence of the disease is a major stumbling-block for both effective clinical management of affected patients as well as for research into this common and debilitating reproductive disease. Laparoscopy is inva...

journal_title：Current opinion in obstetrics & gynecology

authors： Brosens I,Puttemans P,Campo R,Gordts S,Brosens J

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review important considerations in the counseling and management of women over the age of 40 desiring a myomectomy for symptomatic fibroids. RECENT FINDINGS:Women in the late reproductive and perimenopausal years may choose a myomectomy over a hysterectomy for reasons of fertility preservation or ...

journal_title：Current opinion in obstetrics & gynecology

authors： Pepin K,Reddy H,Clark NV

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Growth hormone (GH) has been used as an adjunct in ovulation induction and IVF for 25 years, particularly as an adjunct to ovarian stimulation for women who had a previous poor response to stimulation in an IVF cycle. It does not have US Food and Drug Administration approval for this use. Unfortunatel...

journal_title：Current opinion in obstetrics & gynecology

authors： Hart RJ,Rombauts L,Norman RJ

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article provides an overview of types and trends in managed care, as well as insights into how obstetrician/gynecologists can work with managed care plans to improve process and outcomes for patients. RECENT FINDINGS:Although studies of managed care between 1990 and 2005 generally did not show c...

journal_title：Current opinion in obstetrics & gynecology

authors： Johnson KA,Gee RE

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article provides an overview of the molecular mechanisms underlying adolescent endometriosis and advances in both medical and surgical management. RECENT FINDINGS:Molecular and cellular features of endometriotic lesions differ from eutopic endometrium. There is altered estrogen-mediated c...

journal_title：Current opinion in obstetrics & gynecology

authors： Mama ST

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of recent research and guidelines regarding contraception and breastfeeding. RECENT FINDINGS:Recent studies assessed lactogenesis, breastfeeding rates, and milk supply concerns in patients starting postpartum hormonal contraception. One study showed a small but statistically si...

journal_title：Current opinion in obstetrics & gynecology

authors： Stanton TA,Blumenthal PD

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to summarize recently published clinical and animal-based studies of antenatal corticosteroids, describe current recommendations for practice, and suggest priority areas for future research. RECENT FINDINGS:A single course of antenatal corticosteroids is known to improv...

journal_title：Current opinion in obstetrics & gynecology

authors： Newnham JP,Moss TJ,Nitsos I,Sloboda DM

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Confidential enquiries of maternal deaths in the UK for 1997-1999 revealed that the number of indirect deaths from medical conditions exacerbated by pregnancy was greater than deaths from conditions directly caused by pregnancy. Indirect maternal deaths accounted for 36% of all deaths. Although neopla...

journal_title：Current opinion in obstetrics & gynecology

authors： Chandraharan E,Arulkumaran S

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the role of mullerian inhibiting substance in the context of female reproduction. RECENT FINDINGS:Serum and follicular fluid mullerian inhibiting substance can be measured by commercially available enzyme-linked immunosorbent assay kits. Mullerian inhibiting substance is secreted from small...

journal_title：Current opinion in obstetrics & gynecology

authors： Nakhuda GS

更新日期：2008-06-01 00:00:00

abstract：:We have attempted to review the best available evidence for the commonest gynaecological endoscopic procedures. Controlled studies are the exception rather than the rule, and randomized studies are even rarer. Therefore, the results of large, uncontrolled series must be acknowledged. As a result, for most procedures, ...

journal_title：Current opinion in obstetrics & gynecology

authors： Nagele F,Molnár BG,O'Connor H,Magos AL

更新日期：1996-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews new concepts in the aetiology of recurrent miscarriage, presents new outcome data and evaluates new modalities of treatment for unexplained recurrent miscarriage. RECENT FINDINGS:Preimplantation genetic diagnosis has been considered an option for couples who have structural chrom...

journal_title：Current opinion in obstetrics & gynecology

authors： Carrington B,Sacks G,Regan L

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Thyroid disorders are common in pregnancy and affect maternal and fetal outcome. RECENT FINDINGS:The reference values for normal thyroid function during first and second trimester had been re-evaluated recently. Hypothyroxinemia affects the neuropsychological development of the child. Maternal thyroi...

journal_title：Current opinion in obstetrics & gynecology

authors： Gärtner R

更新日期：2009-12-01 00:00:00

abstract：:In 1991, the abortion literature was characterized by articles relating to 1) epidemiologic issues in abortion care, 2) advances in knowledge and experience with medical abortifacients such as mifepristone (RU 486), and 3) cervical ripening prior to abortion with the use of both mifepristone and prostaglandins. Techni...

journal_title：Current opinion in obstetrics & gynecology

authors： Blumenthal PD

更新日期：1992-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Much attention has been paid to the role of immunology in reproductive success or failure. Every step in the establishment of normal pregnancy has been implicated as a possible site of immune-mediated reproductive failure. The widespread testing of antiphospholipid, antinuclear, antithyroid, and antis...

journal_title：Current opinion in obstetrics & gynecology

authors： Kallen CB,Arici A

更新日期：2003-06-01 00:00:00