Selective oestrogen receptor modulators: a new paradigm for HRT.

Abstract:

:Selective oestrogen receptor modulators are a range of compounds which mimic some, but not all, agonist actions of oestrogen in different tissues. They were developed with the aim of maximizing the benefits of oestrogen-like drugs in a number of important conditions whilst reducing adverse side-effects. The molecular biology of oestrogen receptor signalling is discussed in relation to the pharmacological effects of this class of drugs. The results of clinical trial data with one member of this group (raloxifene) are documented and future developments outlined.

authors

Baynes KC,Compston JE

doi

10.1097/00001703-199806000-00002

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

189-92

issue

3

eissn

1040-872X

issn

1473-656X

journal_volume

10

pub_type

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