Abstract:
:In 1991, the abortion literature was characterized by articles relating to 1) epidemiologic issues in abortion care, 2) advances in knowledge and experience with medical abortifacients such as mifepristone (RU 486), and 3) cervical ripening prior to abortion with the use of both mifepristone and prostaglandins. Technical methods of achieving termination of pregnancy continue to be similar in the United States, the United Kingdom, and Europe, although induction-abortion times are generally slower in Europe than in the United States. Surgically, dilatation and evacuation procedures continue to be more common in the United States than in other countries. The effectiveness of mifepristone is undisputed, and the recommended dose for early first-trimester termination is being compared with lower dose alternative regimens. There is additional evidence that at least in the short term, the negative psychological sequelae of abortion are infrequent and are inconsequential as a public health issue. :In 1991, the abortion literature comprised articles on epidemiologic issues in abortion care advances in abortifacient such as mifepristone (RU-486) and cervical ripening prior to abortion with the use of both mifepristone and prostaglandins. A comprehensive analysis of American women having abortions indicated that although the overall abortion rate had declined since 1980, the rate of unintended pregnancies had remained the same since 1982. Among married, white women over age 30 and white, unmarried women in their twenties abortion rates declined. A prospective cohort study showed no overall differences in nonviable pregnancy outcome, birth weight, and length of gestation between 6188 women who had an abortion and 7073 who did not. In most developed countries prostaglandins are widely used for termination of pregnancy in the 2nd trimester, either as an intra-amniotic or extra-amniotic preparation. In a retrospective analysis, oxytocin was quite effective in achieving rapid, uncomplicated fetoplacental expulsion. It had a mean induction-to-delivery interval of 8.2 (+ or - 5.1) hours, which was significantly better than a mean induction-to-delivery interval of 13.1 (+ or - 7.8) hours in the group that had received prostaglandin E2 suppositories. The World Health Organization estimated that 22-56% of maternal mortality is directly attributable to abortion. In Enugu, Nigeria, the mortality rate from incomplete abortion amounted to 17.9%, and septicemia was documented in 49% of cases. Cervical pretreatment prior to a 2nd-trimester abortion has become standard in many institutions. In a double-blind, double-randomized trial both mifepristone and gemeprost resulted in a cervix that required less force to dilate to 9 mm (P 0.001). The gemeprost group had significantly more side effects than the mifepristone group. Mifepristone is a safe alternative for the termination of pregnancy when the beta human chorionic gonadotropin is below 20,000 IU/L. In spite of the small sample size (n = 50) and a rather high 12% rate of postabortal pelvic inflammatory disease, when the beta human chorionic gonadotropin decreased by at least 40% in the 1st week after receiving mifepristone, the abortion procedure was invariable complete.
journal_name
Curr Opin Obstet Gynecoljournal_title
Current opinion in obstetrics & gynecologyauthors
Blumenthal PDkeywords:
subject
Has Abstractpub_date
1992-08-01 00:00:00pages
506-12issue
4eissn
1040-872Xissn
1473-656Xjournal_volume
4pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:To review minimally invasive modifications of traditional surgeries for female stress urinary incontinence (SUI) in light of increased demand. RECENT FINDINGS:Prior to the synthetic mid-urethral sling (MUS), traditional procedures were used to correct SUI. Often these were retropubic colposuspension ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000579
更新日期:2019-12-01 00:00:00
abstract::The subdermal contraceptive implant etonogestrel (Implanon; NV Organon International, Oss, The Netherlands) exerts complex effects on the endometrium. These include direct effects on the endometrium through endometrial progestin target sites, and indirect effects through suppression of the hypothalamic-pituitary-ovari...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/00001703-200106000-00015
更新日期:2001-06-01 00:00:00
abstract::Acquired immunodeficiency virus infections had recently been the leading cause of death in minority women of reproductive age in several urban cities in the United States. In addition, more than 80% of infants with human immunodeficiency virus type 1 infection acquired the infection perinatally. These alarming data ha...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract:PURPOSE OF REVIEW:This article will review recent changes in the standard of care for olaparib, niraparib, and rucaparib, as well as ongoing trials evaluating this class of drugs in combination with antiangiogenic agents and PD-1/PD-L1 inhibitors. RECENT FINDINGS:Niraparib received FDA approval for use in patients wit...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章
doi:10.1097/GCO.0000000000000675
更新日期:2021-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000256
更新日期:2016-04-01 00:00:00
abstract::Immune based therapies for ovarian carcinoma continue to evolve. The current status of antibody, antibody conjugates, cytokine, cellular, and vaccine based immunotherapy is reviewed. Novel gene transfer strategies that will play an increasing important role in the evolution of immunotherapy are also discussed. ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/00001703-199901000-00006
更新日期:1999-02-01 00:00:00
abstract::The battle against the epidemic of sexually transmitted infections continues but the clinician has new diagnostic and therapeutic weapons. This manuscript reviews new technologies, as well as novel applications of newer methodologies, such as utilization of amplified DNA techniques for urine specimens or patient-colle...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/00001703-199910000-00006
更新日期:1999-10-01 00:00:00
abstract::Transvaginal ultrasonography is emerging as the newest method for the early detection of structural malformations and markers of chromosomal aberrations. According to a multicenter registry on the onset of fetal anomalies, many defects are potentially detectable at an early transvaginal scan. Moreover, cystic hygroma ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/00001703-199504000-00008
更新日期:1995-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to summarize the current evidence on the safety and effectiveness of moving oral contraceptives from prescription-only to over-the-counter (OTC) status. The review also examines women's interest in OTC access to oral contraceptives, as well as potential barriers and facilitat...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000019
更新日期:2013-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The management of benign ovarian lesions in girls is currently a controversial topic in the pediatric surgical literature. The purpose of this review is to highlight the epidemiology of benign ovarian masses, outline preoperative risk stratification strategies, review the indications and importance of...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000400
更新日期:2017-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide an overview of the latest views and evidence available to clinicians managing couples with recurrent early pregnancy loss (RPL). RECENT FINDINGS:RPL is a heterogeneous condition associated with many pathologies, none of which is found in more than 50% of couples after routine investigation...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0b013e32833e124e
更新日期:2010-12-01 00:00:00
abstract::Human papillomavirus (HPV) infection and HPV-associated diseases pose a considerable health care burden in the United States. The morbidity and mortality associated with HPV infection and HPV-associated diseases, ranging from genital warts to cervical cancer, have prompted both the use of screening measures to monitor...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/01.gco.0000216316.10690.c6
更新日期:2006-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to summarize the most important and interesting achievements which have recently been made in the field of female sexual dysfunction. RECENT FINDINGS:During the last years, the characterization of the female sexual response has been re-examined, resulting in new approaches ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0b013e3282f1c733
更新日期:2007-12-01 00:00:00
abstract:PURPOSE OF REVIEW:To analyse the reasons why foetal heart rate (FHR) monitoring failed to fulfil the initial expectations of unequivocally decreasing perinatal morbidity and mortality, and to summarize the most recent advances in this field. RECENT FINDINGS:It is now clear that expectations towards FHR monitoring at t...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0b013e328337233c
更新日期:2010-04-01 00:00:00
abstract::Chronic medical problems and the various medications available to treat them represent an enormous volume of information for the practicing obstetrician. The agents commonly encountered are reviewed here and current literature is explored, where available, including the literature on folates in pregnancy. ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1996-12-01 00:00:00
abstract::Various malignant neoplasms, either primary or secondary, can affect the vagina. The most common primary malignant tumors of the vagina are squamous cell cancers; however, they are among the most uncommon of all primary gynecologic cancers. Vaginal intraepithelial neoplasia is being diagnosed with increasing frequency...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1991-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to understand the current use of minilaparoscopy in the field and how minilaparoscopy compares with traditional laparoscopy in terms of operative times, complications, pain, and cosmesis. RECENT FINDINGS:Although there are few randomized controlled trials comparing minil...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000290
更新日期:2016-08-01 00:00:00
abstract:PURPOSE OF REVIEW:There is a growing clinical consensus that Medicaid sterilization consent protections should be revisited because they impede desired care for many women. Here, we consider the broad social and ideological contexts for past sterilization abuses, beyond informed consent. RECENT FINDINGS:Throughout the...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 历史文章,杂志文章,评审
doi:10.1097/GCO.0000000000000121
更新日期:2014-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Telomere attrition and dysfunction has become a well established pathway involved in organismal aging, not only because it imposes a limitation to cell division and therefore, tissue regeneration but also because telomere homeostasis influences other pathways involved in aging. However, the implicatio...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000456
更新日期:2018-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to discuss the diagnosis, medical complications, and treatment of eating disorders as defined by the newly released Diagnostic and Statistical Manual, 5th edition. RECENT FINDINGS:With the introduction of the Diagnostic and Statistical Manual, 5th edition, the diagnostic...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0000000000000317
更新日期:2016-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Endometriosis is a frequent gynaecological disorder in young women. Colorectal endometriosis accounts for about 90% of all intestinal locations. The effectiveness of medical therapies is poor, and surgery, including colorectal resection, is therefore often required. Since the first description of lapa...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/GCO.0b013e328216f6bc
更新日期:2007-08-01 00:00:00
abstract::Human papillomavirus-related anogenital neoplasia is an active area of basic and clinical research. The research topics are broad based, but mostly are focused on delineating the clinical utility of human papillomavirus testing, the natural history of human papillomavirus infections and associated premalignancies, cha...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1996-02-01 00:00:00
abstract::During the period under review (December 1990 through January 1992), the revised World Health Organization Histological Classification of Ovarian Neoplasms and Tumor-like Lesions was completed, and it is presented herein. This system of classification incorporates recent advances and includes newly recognized entities...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1992-08-01 00:00:00
abstract::The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis ma...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/00001703-200106000-00005
更新日期:2001-06-01 00:00:00
abstract::Infertile couples who seek medical advice have one single hope: to have one or more children. Therefore, pregnancy rates per cycle of any assisted reproductive technique that include early miscarriages and ectopic pregnancies are of little interest to them. They want to know their chances of having a baby. When counse...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Growth hormone (GH) has been used as an adjunct in ovulation induction and IVF for 25 years, particularly as an adjunct to ovarian stimulation for women who had a previous poor response to stimulation in an IVF cycle. It does not have US Food and Drug Administration approval for this use. Unfortunatel...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,meta分析,评审
doi:10.1097/GCO.0000000000000360
更新日期:2017-06-01 00:00:00
abstract::Child sexual abuse is being recognized as a common and serious problem which affects children regardless of their age, sex, socio-economic class, or geographic location. Children of all ages, from infancy to young adulthood, have been victims of abuse. It is well accepted that the number of reported incidents of child...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:
更新日期:1993-12-01 00:00:00
abstract:PURPOSE OF REVIEW:With over 50 million abortions annually and 25% of pregnancies ending in abortion worldwide, abortion is one of the most common medical procedures. Yet abortion-related topics are glaringly absent from medical school curricula in the USA with half of medical schools including no formal training or onl...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章
doi:10.1097/GCO.0000000000000663
更新日期:2020-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Recently some studies have reinforced the arguments supporting the laparoscopic management of early ovarian cancer. These studies and reports questioning the use of laparoscopy in patients with early ovarian cancer will be reviewed. RECENT FINDINGS:Advances in laparoscopic techniques have enabled the...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/01.gco.0000175352.95436.fc
更新日期:2005-08-01 00:00:00
abstract::This review explores the recent experience with, and the basis for, the use of selective estrogen receptor modulators to treat and prevent breast cancer. As new agents are unveiled, they will continue to be tested against tamoxifen. A number of new selective estrogen receptor modulators are in clinical development in ...
journal_title:Current opinion in obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1097/00001703-200202000-00002
更新日期:2002-02-01 00:00:00