Harnessing the power of prevention: human papillomavirus vaccines.

abstract：PURPOSE OF REVIEW:Telomere attrition and dysfunction has become a well established pathway involved in organismal aging, not only because it imposes a limitation to cell division and therefore, tissue regeneration but also because telomere homeostasis influences other pathways involved in aging. However, the implicatio...

journal_title：Current opinion in obstetrics & gynecology

authors： Varela E,Sánchez-de-Puerta I,García-Velasco JA

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the epidemiology of thromboembolism in pregnancy and describe strategies to prevent and treat it. RECENT FINDINGS:The main reason for the increased risk of thrombosis in pregnancy is hypercoagulability. Other risk factors include a history of thrombosis, inh...

journal_title：Current opinion in obstetrics & gynecology

authors： James AH

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:More than 50% of all gynecologic cancers can be classified as rare tumors (defined as an incidence of <6 per 100 000) and as such represent a major challenge for clinicians. RECENT FINDINGS:The rapidly increasing number of targeted therapies provides a unique opportunity to improve treatment options ...

journal_title：Current opinion in obstetrics & gynecology

authors： Ray-Coquard I,Pujade-Lauraine E,Ledermann JA

更新日期：2015-02-01 00:00:00

abstract：:The battle against the epidemic of sexually transmitted infections continues but the clinician has new diagnostic and therapeutic weapons. This manuscript reviews new technologies, as well as novel applications of newer methodologies, such as utilization of amplified DNA techniques for urine specimens or patient-colle...

journal_title：Current opinion in obstetrics & gynecology

authors： Biro FM

更新日期：1999-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Currently, a number of different stress urinary incontinence (SUI) procedures exist. The relatively recent adoption of the midurethral sling into clinical practice has changed the surgical management of SUI. This critical evaluation of the trends in SUI surgery emphasizes the public health burden of S...

journal_title：Current opinion in obstetrics & gynecology

authors： Geller EJ,Wu JM

更新日期：2013-10-01 00:00:00

abstract：:Early ectopic pregnancy screening using vaginal ultrasonographic technology together with measurement of beta human chorionic gonadotropin (beta-hCG) and human chorionic somatomammotropin is possible within the first 2 weeks of the missing menses, prior to the appearance of symptoms. This article summarizes the main a...

journal_title：Current opinion in obstetrics & gynecology

authors： Mettler L

更新日期：1991-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been associated with a wide range of human disease states and the global epidemic, particularly in reproductive aged women, has led to a focus on this complex hormones role in human reproduction. Indeed vitamin D receptors are found throughout the reproductive tract in the ova...

journal_title：Current opinion in obstetrics & gynecology

authors： Franasiak JM,Lara EE,Pellicer A

更新日期：2017-08-01 00:00:00

abstract：:Few randomized studies have addressed the best choice of adjuvant radiation therapy after surgery for stage I endometrial cancer. Although whole pelvic radiation decreases the incidence of pelvic and vaginal cancer recurrence, there is no convincing evidence that it improves survival in women who have been completely ...

journal_title：Current opinion in obstetrics & gynecology

authors： Naumann RW

更新日期：2002-02-01 00:00:00

abstract：:Recent advances in seemingly remote areas of investigation, i.e. yeast cell cycle research and DNA amplifications, have opened spectacular avenues for understanding reproduction. The new insights on the single cell and subcellular level of processes, such as egg maturation, sperm-egg interaction and implantation enhan...

journal_title：Current opinion in obstetrics & gynecology

authors： Zilberstein M,Seibel MM

更新日期：1994-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the latest developments in screening and diagnosis of non-chromosomal genetic diseases. RECENT FINDINGS:Major recent advances include the completion of the Human Genome Project, the use of microarray and related technologies for mass screening and diagnosis of thousands of genetic abnormali...

journal_title：Current opinion in obstetrics & gynecology

authors： Lau TK,Leung TN

更新日期：2005-04-01 00:00:00

abstract：:Reflective of increasing attention to male sterilization are the development in China of the so-called "no scalpel" vasectomy technique, experiments with predicting reversibility through measurement of the cytometry of testicular aspirates, and research on issues such as the effects of vasectomy on spermatogenesis...

journal_title：Current opinion in obstetrics & gynecology

authors： Davis JE

更新日期：1990-08-01 00:00:00

abstract：:Human papillomavirus-related anogenital neoplasia is an active area of basic and clinical research. The research topics are broad based, but mostly are focused on delineating the clinical utility of human papillomavirus testing, the natural history of human papillomavirus infections and associated premalignancies, cha...

journal_title：Current opinion in obstetrics & gynecology

authors： Duggan MA

更新日期：1996-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To present the outcome of laparoscopic resection for bowel endometriosis. RECENT FINDINGS:In the last 12 months, numerous articles have been published to demonstrate and underline the efficiency and feasibility of the laparoscopic approach in the treatment of bowel endometriosis. SUMMARY:Endometrios...

journal_title：Current opinion in obstetrics & gynecology

authors： Ruffo G,Rossini R

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Examine recent evidence of randomized controlled trials and meta-analyses regarding the effect of maternal vitamin D status and supplementation over obstetrical and offspring outcomes. RECENT FINDINGS:Maternal serum 25-hydroxyvitamin [25(OH)D] progressively declines during pregnancy because of fetal ...

journal_title：Current opinion in obstetrics & gynecology

authors： Pérez-López FR,Pilz S,Chedraui P

更新日期：2020-10-01 00:00:00

abstract：:Transvaginal ultrasonography is emerging as the newest method for the early detection of structural malformations and markers of chromosomal aberrations. According to a multicenter registry on the onset of fetal anomalies, many defects are potentially detectable at an early transvaginal scan. Moreover, cystic hygroma ...

journal_title：Current opinion in obstetrics & gynecology

authors： Rottem S

更新日期：1995-04-01 00:00:00

abstract：:Infertility is a common medical problem resulting from one or more defects in the reproductive tract. Of the known causes of infertility, cervico-utero-tubal factors are important because they are generally manageable. Cervical factors include changes in cervical architecture, mucus, or both, resulting in a hostile en...

journal_title：Current opinion in obstetrics & gynecology

authors： Markham S

更新日期：1991-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The management of uterine fibroids in patients requiring treatment who desire future fertility remains controversial. Myomectomy has been the most common operative procedure to improve pregnancy rates and outcomes. Uterine fibroid embolization is an increasingly popular, minimally invasive treatment f...

journal_title：Current opinion in obstetrics & gynecology

authors： Goldberg J,Pereira L

更新日期：2006-08-01 00:00:00

abstract：:The obstetrician-gynecologist must assume a dual role in the future provision of health care to women. Not only should the obstetrician-gynecologist function as a consultant for medical and surgical problems peculiar to the female reproductive tract, but also assume a broader-based role for preventive medicine and hea...

journal_title：Current opinion in obstetrics & gynecology

authors： Laube DW

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Polycystic ovary syndrome is one of the most common endocrinopathies affecting premenopausal women. This review focuses on this major cause of hyperandrogenism in adolescents and young women, highlighting new diagnostic and therapeutic strategies that are under investigation. The pathophysiologic role...

journal_title：Current opinion in obstetrics & gynecology

authors： Stafford DE,Gordon CM

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Hysteroscopic myomectomy was a revolution for surgical treatment of symptomatic submucosal myoma. RECENT FINDINGS:A new International Federation of Gynecology and Obstetrics classification for myoma was recently described. Type 0, 1 and 2 are submucosal like in the European Society for Human Reproduc...

journal_title：Current opinion in obstetrics & gynecology

authors： Capmas P,Levaillant JM,Fernandez H

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Immune checkpoint blockade (ICB) is a promising area of cancer therapeutic research. Therapies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) mechanism of tumor immune evasion have resulted in durable responses in many difficult-to-treat tumor types. While these...

journal_title：Current opinion in obstetrics & gynecology

authors： Chin CD,Fares CM,Konecny GE,Rao J

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Emergency contraception in the past two decades had been proven to be effective and well tolerated. Counseling and advance provision and prescription of emergency contraception have been embraced by professional organizations in practice guidelines for its potential to reduce the number of unintended ...

journal_title：Current opinion in obstetrics & gynecology

authors： Broekhuizen FF

更新日期：2009-08-01 00:00:00

abstract：:Immune based therapies for ovarian carcinoma continue to evolve. The current status of antibody, antibody conjugates, cytokine, cellular, and vaccine based immunotherapy is reviewed. Novel gene transfer strategies that will play an increasing important role in the evolution of immunotherapy are also discussed. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Vanderkwaak TJ,Alvarez RD

更新日期：1999-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article provides an overview of the molecular mechanisms underlying adolescent endometriosis and advances in both medical and surgical management. RECENT FINDINGS:Molecular and cellular features of endometriotic lesions differ from eutopic endometrium. There is altered estrogen-mediated c...

journal_title：Current opinion in obstetrics & gynecology

authors： Mama ST

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical utility of sperm DNA fragmentation tests needs to be revisited in light of increasing evidence of detrimental effect of sperm DNA damage on reproductive outcomes. RECENT FINDINGS:Current evidence supports the association between high sperm DNA fragmentation and poor outcomes with regards...

journal_title：Current opinion in obstetrics & gynecology

authors： Agarwal A,Cho CL,Esteves SC

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The increased risk of infertility in men with varicocele is well established. Varicocelectomy has been shown to improve semen parameters and increase pregnancy rates. Yet varicocele pathophysiology is poorly understood and potential implications for testosterone production are less clear. Evidence sug...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanrikut C,McQuaid JW,Goldstein M

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Antiphospholipid syndrome (APS) is defined as the association of thrombotic events and/or obstetric morbidity in patients persistently positive for antiphospholipid antibodies (aPL). In this review, we will highlight the most important clinical presentations of APS with a focus on the obstetric morbid...

journal_title：Current opinion in obstetrics & gynecology

authors： Schreiber K,Radin M,Sciascia S

更新日期：2017-12-01 00:00:00

abstract：:The corpus luteum is controlled by luteinizing hormone (LH) and intraovarian morphofunctional specialization and autocrine/paracrine mechanisms. Corpus luteal insufficiency produces luteal phase defects (LPD). The poor precision and validation of endometrial histologic dating and single or random multiple serum proges...

journal_title：Current opinion in obstetrics & gynecology

authors： Dawood MY

更新日期：1994-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review is timely and relevant for several reasons. The incidence of adenomyosis begins to rise from the mid-thirties. Moreover, more women are delaying their first pregnancy until later in their thirties or forties, and consequently adenomyosis is encountered more frequently in the fertility clin...

journal_title：Current opinion in obstetrics & gynecology

authors： Matalliotakis IM,Katsikis IK,Panidis DK

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The review aims to summarize recent data about vascular endothelial growth factor and its implications in the normal endometrium during the menstrual cycle, implantation window and early pregnancy. RECENT FINDINGS:Angiogenesis is crucial for the development of endometrium as well as for embryo implan...

journal_title：Current opinion in obstetrics & gynecology

authors： Nardo LG

更新日期：2005-08-01 00:00:00