New clinical research strategies for rare gynecologic malignancies.

abstract：:Current studies verify the safety of surgery in the elderly. Delirium is a costly complication, but its incidence and severity can be reduced by pre- and postoperative interventions. Avoidance of even mild hypothermia has now been shown to reduce cardiovascular morbidity. New information available on the cardiovascula...

journal_title：Current opinion in obstetrics & gynecology

authors： Miller KL

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Venous thromboembolism is the leading cause of maternal death in the UK. Thrombophilia underlies many thrombotic disorders in pregnancy. The high prevalence of thrombophilic defects in the population, the association of defects with venous thromboembolism and the special considerations for management ...

journal_title：Current opinion in obstetrics & gynecology

authors： Robertson L,Greer I

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current role of radiation therapy and specific types of radiation therapy used in the management of early stage, locoregionally advanced, and metastatic breast cancer. RECENT FINDINGS:The role of radiation therapy in the management of breast cancer has not changed in recent decades, h...

journal_title：Current opinion in obstetrics & gynecology

authors： McCloskey SA,Lee SP,Steinberg ML

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The past 15 years have seen a five-fold increase in the incidence of acquired heart disease as a cause of maternal mortality in the UK, and advances in the surgical correction of congenital heart disease have enabled many more women to survive childhood and present at the antenatal clinic. This review...

journal_title：Current opinion in obstetrics & gynecology

authors： Curry R,Swan L,Steer PJ

更新日期：2009-12-01 00:00:00

abstract：:Approximately 12 million women worldwide use the levonorgestrel-releasing intrauterine system (IUS), with approximately 180,000 users of this IUS currently reported in Austria. A patient satisfaction study of 591 women in Austria revealed a high number of 'very satisfied' (79%) and 'satisfied' (19%) patients. Reliabil...

journal_title：Current opinion in obstetrics & gynecology

authors： Concin H,Bösch H,Hintermüller P,Hohlweg T,Mursch-Edlmayr G,Pinnisch B,Schmidl-Amann S,Schulz-Greinwald G,Unterlerchner D,Wagner T,Mattle V,Wildt L,Fiala C

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight relevant strategies to overcome poly(ADP-ribose) polymerase (PARP) inhibitor resistance and present key clinical trials. RECENT FINDINGS:The use of PARP inhibition (PARPi) for frontline maintenance offers substantial clinical benefit in patients with homologous recombination-deficient tu...

journal_title：Current opinion in obstetrics & gynecology

authors： Hinchcliff E,Chelariu-Raicu A,Westin SN

更新日期：2021-02-01 00:00:00

abstract：:In 1991, the abortion literature was characterized by articles relating to 1) epidemiologic issues in abortion care, 2) advances in knowledge and experience with medical abortifacients such as mifepristone (RU 486), and 3) cervical ripening prior to abortion with the use of both mifepristone and prostaglandins. Techni...

journal_title：Current opinion in obstetrics & gynecology

authors： Blumenthal PD

更新日期：1992-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Because of widespread availability of highly active antiretroviral therapy in the developed world, a large proportion of children with perinatally acquired HIV have survived to adolescence and young adulthood. Although their survival is remarkable, many now experience the long-term effects of HIV infe...

journal_title：Current opinion in obstetrics & gynecology

authors： Koenig LJ,Nesheim S,Abramowitz S

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The recovery of immature oocytes followed by in-vitro maturation (IVM) and in-vitro fertilization is an attractive alternative to conventional in-vitro fertilization treatment in which controlled ovarian stimulation with gonadotropins is used to increase the number of available oocytes and embryos. Si...

journal_title：Current opinion in obstetrics & gynecology

authors： Chian RC,Lim JH,Tan SL

更新日期：2004-06-01 00:00:00

abstract：:Various malignant neoplasms, either primary or secondary, can affect the vagina. The most common primary malignant tumors of the vagina are squamous cell cancers; however, they are among the most uncommon of all primary gynecologic cancers. Vaginal intraepithelial neoplasia is being diagnosed with increasing frequency...

journal_title：Current opinion in obstetrics & gynecology

authors： Benedet JL

更新日期：1991-02-01 00:00:00

abstract：:Chronic medical problems and the various medications available to treat them represent an enormous volume of information for the practicing obstetrician. The agents commonly encountered are reviewed here and current literature is explored, where available, including the literature on folates in pregnancy. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Colie CF

更新日期：1996-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose is to review current recommendations for the evaluation and management of delayed puberty in the female patient. RECENT FINDINGS:Kisspeptin activation has emerged as an important factor for initiation of pubertal development. Causes of delayed puberty can be considered in four main catego...

journal_title：Current opinion in obstetrics & gynecology

authors： Trotman GE

更新日期：2016-10-01 00:00:00

abstract：:The battle against the epidemic of sexually transmitted infections continues but the clinician has new diagnostic and therapeutic weapons. This manuscript reviews new technologies, as well as novel applications of newer methodologies, such as utilization of amplified DNA techniques for urine specimens or patient-colle...

journal_title：Current opinion in obstetrics & gynecology

authors： Biro FM

更新日期：1999-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To avoid both overtreatment and undertreatment accurate risk assessment is mandatory. The present review gives an overview of recently published articles covering prognostic and predictive factors for adjuvant therapy in early breast cancer. RECENT FINDINGS:Gene expression signatures enhance prognost...

journal_title：Current opinion in obstetrics & gynecology

authors： Schmidt M

更新日期：2020-02-01 00:00:00

abstract：:Our understanding of the causes, mechanisms, and prenatal management of fetal obstructive uropathy has increased significantly. Improved methods of prenatal evaluation have allowed the better selection of fetuses for invasive therapy, and studies indicate better survival and renal outcomes in carefully selected cases....

journal_title：Current opinion in obstetrics & gynecology

authors： Johnson MP,Freedman AL

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article provides an overview of the molecular mechanisms underlying adolescent endometriosis and advances in both medical and surgical management. RECENT FINDINGS:Molecular and cellular features of endometriotic lesions differ from eutopic endometrium. There is altered estrogen-mediated c...

journal_title：Current opinion in obstetrics & gynecology

authors： Mama ST

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the role of mullerian inhibiting substance in the context of female reproduction. RECENT FINDINGS:Serum and follicular fluid mullerian inhibiting substance can be measured by commercially available enzyme-linked immunosorbent assay kits. Mullerian inhibiting substance is secreted from small...

journal_title：Current opinion in obstetrics & gynecology

authors： Nakhuda GS

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review updated information on the influence of endometrial scratching on IVF. RECENT FINDINGS:Endometrial receptivity remains an important rate-limiting step affecting the success of IVF. The current evidence on the effect of endometrial scratching on IVF ranges from marked improvement, no differe...

journal_title：Current opinion in obstetrics & gynecology

authors： Ko JK,Ng EH

更新日期：2016-06-01 00:00:00

abstract：:Studies published in the past year have attempted to model the pathophysiology of the twin-twin transfusion syndrome and also to establish the minimal diagnostic criteria for the condition. Many papers focused on treatment regimens and their sequelae. Aggressive treatment with serial amnioreduction continues to predom...

journal_title：Current opinion in obstetrics & gynecology

authors： Filkins KA,Beverly SE

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The last several years have seen a number of important clinical and academic advances in long-acting reversible contraceptive (LARC) methods, such that many professional medical organizations now recommend these methods as first-line contraception for all women. RECENT FINDINGS:Recent data support th...

journal_title：Current opinion in obstetrics & gynecology

authors： Conti J,Shaw K

更新日期：2015-12-01 00:00:00

abstract：:Outpatient hysteroscopy has shown good correlation of findings compared with inpatient hysteroscopy, but one limitation is pain and discomfort in some women, and vasovagal reaction. Various forms of local anaesthesia have been evaluated in the past year, with controversial results, and a narrow 3.5 mm sheath hysterosc...

journal_title：Current opinion in obstetrics & gynecology

authors： Marana R,Marana E,Catalano GF

更新日期：2001-08-01 00:00:00

abstract：:Neuromodulation is one option for the management of a wide variety of lower urinary tract disorders, including non-neuropathic and neuropathic bladder dysfunctions. The mechanisms of action of the reported techniques remain unclear; urodynamic changes are minimal, but symptomatic improvements are common. Although the ...

journal_title：Current opinion in obstetrics & gynecology

authors： Hasan ST,Neal DE

更新日期：1998-10-01 00:00:00

abstract：:Ultrasound prenatal diagnosis of structural anomalies has become almost a separate branch of obstetrics. The advantages of performing ultrasound in pregnancies at high risk for fetal structural anomalies are clear. Patients and the news media have placed ever-increasing expectations on persons performing diagnostic ul...

journal_title：Current opinion in obstetrics & gynecology

authors： Gomez KJ,Copel JA

更新日期：1993-04-01 00:00:00

abstract：:Acquired immunodeficiency virus infections had recently been the leading cause of death in minority women of reproductive age in several urban cities in the United States. In addition, more than 80% of infants with human immunodeficiency virus type 1 infection acquired the infection perinatally. These alarming data ha...

journal_title：Current opinion in obstetrics & gynecology

authors： Sison AV

更新日期：1992-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The most appropriate surgical approach for uterine preservation still remains the subject of ongoing controversy. Uterine suspension procedures can be performed abdominally, vaginally, or laparoscopically. This article focuses on the three different laparoscopic approaches of uterine suspension for ut...

journal_title：Current opinion in obstetrics & gynecology

authors： Lin LL,Ho MH,Haessler AL,Betson LH,Alinsod RM,Liu CY,Bhatia NN

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lazarin GA,Goldberg JD

更新日期：2016-04-01 00:00:00

abstract：:The subdermal contraceptive implant etonogestrel (Implanon; NV Organon International, Oss, The Netherlands) exerts complex effects on the endometrium. These include direct effects on the endometrium through endometrial progestin target sites, and indirect effects through suppression of the hypothalamic-pituitary-ovari...

journal_title：Current opinion in obstetrics & gynecology

authors： Varma R,Mascarenhas L

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cervical cytology screening programs have dramatically decreased rates of invasive cancer in developed countries, most guidelines in the USA were overaggressive in their management of abnormal cytology in adolescents and young women. These management strategies resulted in costly over-treatme...

journal_title：Current opinion in obstetrics & gynecology

authors： Moscicki AB

更新日期：2005-10-01 00:00:00

abstract：:Urinary incontinence remains a common problem that adversely affects the quality of life of millions of women. In detrusor instability, treatment measures often lack efficacy or are accompanied by unacceptable side effects. In this review, standard treatments are discussed, together with recent pharmacologic advances ...

journal_title：Current opinion in obstetrics & gynecology

authors： Wise B,Cardozo L

更新日期：1991-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate the impact of early pregnancy complications involving placentation and early placental development on adverse obstetric outcome in ongoing and subsequent pregnancies. RECENT FINDINGS:We found an increased risk of adverse outcome (odds ratio >2.0) in ongoing pregnancies of preterm delivery...

journal_title：Current opinion in obstetrics & gynecology

authors： Jauniaux E,Van Oppenraaij RH,Burton GJ

更新日期：2010-12-01 00:00:00