Delayed puberty in the female patient.

abstract：PURPOSE OF REVIEW:To review recent findings related to possible causes of recurrent implantation failure of endometrial origin in normal uterus. RECENT FINDINGS:Recent evidences suggest that in apparently normal endometria, RIF may associate with molecular and functional changes in the uterus such as abnormal endometr...

journal_title：Current opinion in obstetrics & gynecology

authors： Bellver J,Simón C

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been associated with a wide range of human disease states and the global epidemic, particularly in reproductive aged women, has led to a focus on this complex hormones role in human reproduction. Indeed vitamin D receptors are found throughout the reproductive tract in the ova...

journal_title：Current opinion in obstetrics & gynecology

authors： Franasiak JM,Lara EE,Pellicer A

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To avoid both overtreatment and undertreatment accurate risk assessment is mandatory. The present review gives an overview of recently published articles covering prognostic and predictive factors for adjuvant therapy in early breast cancer. RECENT FINDINGS:Gene expression signatures enhance prognost...

journal_title：Current opinion in obstetrics & gynecology

authors： Schmidt M

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Gonadotrophin in IVF increases the number of oocytes retrieved, and many doctors regard a high number of oocytes as a measurement of success in IVF. Thus, the dogma of more oocytes provides better IVF success has been broadly accepted. However, some European fertility specialists have argued against t...

journal_title：Current opinion in obstetrics & gynecology

authors： Lindenberg S,Almind GJ,Lindenberg FB

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Benefit of micronutrient supplementation on female fertility. RECENT FINDINGS:Reports of randomized trials are rare. Most studies are focused on multivitamin supplementations. For some micronutrients, a positive impact on fertility could be shown. This article reviews the available clinical studies a...

journal_title：Current opinion in obstetrics & gynecology

authors： Buhling KJ,Grajecki D

更新日期：2013-06-01 00:00:00

abstract：:The battle against the epidemic of sexually transmitted infections continues but the clinician has new diagnostic and therapeutic weapons. This manuscript reviews new technologies, as well as novel applications of newer methodologies, such as utilization of amplified DNA techniques for urine specimens or patient-colle...

journal_title：Current opinion in obstetrics & gynecology

authors： Biro FM

更新日期：1999-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Ductal carcinoma in situ (DCIS) accounts for approximately 20% of mammographically diagnosed breast cancers. Currently, there is a trend to consider DCIS as a lesion for which treatment deescalation is advocated to avoid overtreatment, that is, radiotherapy in addition to breast-conserving surgery or ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lebeau A,Kühn T

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Because of widespread availability of highly active antiretroviral therapy in the developed world, a large proportion of children with perinatally acquired HIV have survived to adolescence and young adulthood. Although their survival is remarkable, many now experience the long-term effects of HIV infe...

journal_title：Current opinion in obstetrics & gynecology

authors： Koenig LJ,Nesheim S,Abramowitz S

更新日期：2011-10-01 00:00:00

abstract：:This review explores some of the implications for a balanced approach to the ethics of maternal participation in clinical research, from the perspective of the fetus as a patient, which is a central concept in obstetric ethics. The review therefore begins with an account of this topic, followed by an examination of so...

journal_title：Current opinion in obstetrics & gynecology

authors： Chervenak FA,McCullough LB

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight relevant strategies to overcome poly(ADP-ribose) polymerase (PARP) inhibitor resistance and present key clinical trials. RECENT FINDINGS:The use of PARP inhibition (PARPi) for frontline maintenance offers substantial clinical benefit in patients with homologous recombination-deficient tu...

journal_title：Current opinion in obstetrics & gynecology

authors： Hinchcliff E,Chelariu-Raicu A,Westin SN

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Pelvic organ prolapse is a common disease that negatively affects the lives of women. To date, basic science research into the pathogenesis of prolapse has been limited. The vagina and its supportive connective tissues provide one of the primary mechanisms of support to the pelvic organs. This review ...

journal_title：Current opinion in obstetrics & gynecology

authors： Alperin M,Moalli PA

更新日期：2006-10-01 00:00:00

abstract：:The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Mahutte NG,Arici A

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the latest views and evidence available to clinicians managing couples with recurrent early pregnancy loss (RPL). RECENT FINDINGS:RPL is a heterogeneous condition associated with many pathologies, none of which is found in more than 50% of couples after routine investigation...

journal_title：Current opinion in obstetrics & gynecology

authors： Tang AW,Quenby S

更新日期：2010-12-01 00:00:00

abstract：:In contrast to the reduction in perinatal mortality in high-risk pregnancies, screening of low-risk pregnancies with umbilical artery Doppler ultrasonography has shown no benefit. Advances in pathophysiology question the assumption that the placenta is hypoxic in fetal growth restriction, with absent end-diastolic fre...

journal_title：Current opinion in obstetrics & gynecology

authors： Burrell SJ,Kingdom JC

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide clinicians with a review of recent research and clinically applicable tools regarding teen pregnancy. RECENT FINDINGS:Teen pregnancy rates have declined but still remain a significant problem in the USA. Teen pregnancy prevention was identified by Centers for Disease Control and Prevention...

journal_title：Current opinion in obstetrics & gynecology

authors： McCracken KA,Loveless M

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cervical cytology screening programs have dramatically decreased rates of invasive cancer in developed countries, most guidelines in the USA were overaggressive in their management of abnormal cytology in adolescents and young women. These management strategies resulted in costly over-treatme...

journal_title：Current opinion in obstetrics & gynecology

authors： Moscicki AB

更新日期：2005-10-01 00:00:00

abstract：:Many different disease processes can result in a phenotype of hirsutism, anovulation, and oligomenorrhea or amenorrhea. An important goal of reproductive endocrinologists is to identify specific genetic diseases that can produce the hyperandrogenic phenotype. Two genetic disorders that can result in the hyperandrogeni...

journal_title：Current opinion in obstetrics & gynecology

authors： Barbieri RL

更新日期：1991-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate the role of fluorodeoxyglucose (FDG) PET/CT as cancer response testing in gynecological malignancies. RECENT FINDINGS:The application of FDG PET/CT in patients with endometrial and ovarian cancer to evaluate treatment response was found to have no clinical benefits.Patients with cervical ...

journal_title：Current opinion in obstetrics & gynecology

authors： Amit A,Person O,Keidar Z

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We present an update on amenorrhea in adolescent girls and young women. Amenorrhea may herald the onset of estrogen deficiency, which can adversely affect peak bone mass and ultimate risk of osteoporosis. RECENT FINDINGS:Adolescence is a critical period for bone accretion. Important modifiable factor...

journal_title：Current opinion in obstetrics & gynecology

authors： Gordon CM,Nelson LM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Prescribing habits for the treatment of symptomatic hypogonadism have recently stirred controversy surrounding testosterone replacement therapy. As a result, the gynecologist will need to recognize this iatrogenic form of decreased sperm production in couples seeking fertility advice. We have compiled...

journal_title：Current opinion in obstetrics & gynecology

authors： Owen RC,Elkelany OO,Kim ED

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The study of embryonic development through conventional microscopy has contributed significantly to the success of IVF. However, clinical pregnancy rates per transfer remain as low as 30% according to the latest records of European society if human reproduction and society if assisted reproduction. Co...

journal_title：Current opinion in obstetrics & gynecology

authors： Basile N,Elkhatib I,Meseguer M

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Borderline tumors of the ovary are seen commonly in obstetrics and gynecology practices. This review will outline the most recent information regarding the epidemiology, molecular pathogenesis, pathology, and clinical management of these tumors. RECENT FINDINGS:In the past, borderline ovarian tumors ...

journal_title：Current opinion in obstetrics & gynecology

authors： Crispens MA

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review important considerations in the counseling and management of women over the age of 40 desiring a myomectomy for symptomatic fibroids. RECENT FINDINGS:Women in the late reproductive and perimenopausal years may choose a myomectomy over a hysterectomy for reasons of fertility preservation or ...

journal_title：Current opinion in obstetrics & gynecology

authors： Pepin K,Reddy H,Clark NV

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lazarin GA,Goldberg JD

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This article will review recent changes in the standard of care for olaparib, niraparib, and rucaparib, as well as ongoing trials evaluating this class of drugs in combination with antiangiogenic agents and PD-1/PD-L1 inhibitors. RECENT FINDINGS:Niraparib received FDA approval for use in patients wit...

journal_title：Current opinion in obstetrics & gynecology

authors： Washington CR,Moore KN

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Monochorionic compared with dichorionic twins have disproportionately high fetal loss rates, perinatal mortality and morbidity. This is because of the unpredictable vascular anastomoses and the often asymmetrical distribution of the single placenta between both twins. RECENT FINDINGS:The pathophysiol...

journal_title：Current opinion in obstetrics & gynecology

authors： Lewi L,Van Schoubroeck D,Gratacós E,Witters I,Timmerman D,Deprest J

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the techniques recently tested in both animal models and humans to provide a state-of-the-art on adult stem cell ovarian transplant to achieve ovarian rejuvenation in patients with diminished ovarian reserves. RECENT FINDINGS:As the firsts reports of spontaneous pregnancies achieved after b...

journal_title：Current opinion in obstetrics & gynecology

authors： Herraiz S,Pellicer N,Romeu M,Pellicer A

更新日期：2019-06-01 00:00:00

abstract：:In the past year, new data have been published on the molecular biology of human papillomavirus infections and their relationship to cervical neoplasia. As molecular techniques have become more sophisticated and as the molecular knowledge of human papilloma-virus infections has been pursued in greater depth, it is inc...

journal_title：Current opinion in obstetrics & gynecology

authors： Richart RM,Wright TC Jr

更新日期：1992-10-01 00:00:00

abstract：:Human papillomavirus-related anogenital neoplasia is an active area of basic and clinical research. The research topics are broad based, but mostly are focused on delineating the clinical utility of human papillomavirus testing, the natural history of human papillomavirus infections and associated premalignancies, cha...

journal_title：Current opinion in obstetrics & gynecology

authors： Duggan MA

更新日期：1996-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Many minimally invasive techniques have recently been introduced for the management of uterine fibroids. The purpose of this review is to analyse recent data for techniques that are used to manage uterine fibroids. RECENT FINDINGS:Laparoscopic myomectomy has provided a minimally invasive alternative ...

journal_title：Current opinion in obstetrics & gynecology

authors： Falcone T,Bedaiwy MA

更新日期：2002-08-01 00:00:00