Updates in the treatment of ductal carcinoma in situ of the breast.

abstract：:Many different disease processes can result in a phenotype of hirsutism, anovulation, and oligomenorrhea or amenorrhea. An important goal of reproductive endocrinologists is to identify specific genetic diseases that can produce the hyperandrogenic phenotype. Two genetic disorders that can result in the hyperandrogeni...

journal_title：Current opinion in obstetrics & gynecology

authors： Barbieri RL

更新日期：1991-06-01 00:00:00

abstract：:The management of advanced ovarian cancer relies on appropriate surgical cytoreduction in conjunction with appropriate adjuvant chemotherapy. In the past year several studies have continued to support aggressive cytoreduction at the initial operation, including for stage IV disease, as well as in a second-look setting...

journal_title：Current opinion in obstetrics & gynecology

authors： Chen LM,Berek JS

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Polycystic ovary syndrome is one of the most common endocrinopathies affecting premenopausal women. This review focuses on this major cause of hyperandrogenism in adolescents and young women, highlighting new diagnostic and therapeutic strategies that are under investigation. The pathophysiologic role...

journal_title：Current opinion in obstetrics & gynecology

authors： Stafford DE,Gordon CM

更新日期：2002-10-01 00:00:00

abstract：:This paper reviews psychologic aspects of sexual abuse in female adolescents. It documents that sexual abuse is widespread, occurring at an alarming rate at all socioeconomic levels of society. It is perpetrated principally by adult men in the victim's family. Often its effects are tragic. Adolescent female sexual abu...

journal_title：Current opinion in obstetrics & gynecology

authors： Jeffrey TB,Jeffrey LK

更新日期：1991-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to provide an update for the GP on selected common vulvar concerns in prepubertal girls. Presentation, diagnostic criteria, and management of common vulvar conditions will be described. The following conditions are frequently encountered and may pose diagnostic or manage...

journal_title：Current opinion in obstetrics & gynecology

authors： Vilano SE,Robbins CL

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:We present an update on amenorrhea in adolescent girls and young women. Amenorrhea may herald the onset of estrogen deficiency, which can adversely affect peak bone mass and ultimate risk of osteoporosis. RECENT FINDINGS:Adolescence is a critical period for bone accretion. Important modifiable factor...

journal_title：Current opinion in obstetrics & gynecology

authors： Gordon CM,Nelson LM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Sex trafficking of adolescents and young adults is both a human rights violation and a public health problem, globally and in the United States. Healthcare providers, including obstetricians and gynecologists, interact with victims, often while they remain under their traffickers' control, but because...

journal_title：Current opinion in obstetrics & gynecology

authors： Chaffee T,English A

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent findings related to possible causes of recurrent implantation failure of endometrial origin in normal uterus. RECENT FINDINGS:Recent evidences suggest that in apparently normal endometria, RIF may associate with molecular and functional changes in the uterus such as abnormal endometr...

journal_title：Current opinion in obstetrics & gynecology

authors： Bellver J,Simón C

更新日期：2018-08-01 00:00:00

abstract：:Minimally invasive surgery enables the avoidance of, preparation for, participation in, and treatment of complications following assisted reproductive technology (ART). The major recent changes are, the development of surgical techniques to diagnose and treat intrafallopian tubal abnormalities; the use of operative en...

journal_title：Current opinion in obstetrics & gynecology

authors： Wood C

更新日期：1994-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Antiphospholipid syndrome (APS) is defined as the association of thrombotic events and/or obstetric morbidity in patients persistently positive for antiphospholipid antibodies (aPL). In this review, we will highlight the most important clinical presentations of APS with a focus on the obstetric morbid...

journal_title：Current opinion in obstetrics & gynecology

authors： Schreiber K,Radin M,Sciascia S

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Thyroid disorders are common in pregnancy and affect maternal and fetal outcome. RECENT FINDINGS:The reference values for normal thyroid function during first and second trimester had been re-evaluated recently. Hypothyroxinemia affects the neuropsychological development of the child. Maternal thyroi...

journal_title：Current opinion in obstetrics & gynecology

authors： Gärtner R

更新日期：2009-12-01 00:00:00

abstract：:Ovarian stimulation is applied during infertility management either alone or in conjunction with intrauterine insemination and assisted reproductive technologies. At the present time, the two main medications used for ovarian stimulation include an oral antiestrogen, clomiphene citrate, and injectable gonadotropins. I...

journal_title：Current opinion in obstetrics & gynecology

authors： Mitwally MF,Casper RF

更新日期：2002-06-01 00:00:00

abstract：:Specialized fetal echocardiography at 18 to 22 weeks for high-risk groups is well established as being sensitive and specific for most cardiac abnormalities. Early fetal echocardiography (< 16(+0) weeks, i.e. 16 weeks and 0 days) is a feasible alternative to mid second trimester scanning for families at risk of congen...

journal_title：Current opinion in obstetrics & gynecology

authors： Carvalho JS

更新日期：2001-04-01 00:00:00

abstract：:Misoprostol, an orally active prostaglandin E1 analogue, has been used widely by the vaginal and oral routes for labour induction at or near term. Several recent trials have confirmed that it is highly effective. Overall caesarean section rates appear to be reduced, despite a relative increase in caesarean sections fo...

journal_title：Current opinion in obstetrics & gynecology

authors： Hofmeyr GJ

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the latest views and evidence available to clinicians managing couples with recurrent early pregnancy loss (RPL). RECENT FINDINGS:RPL is a heterogeneous condition associated with many pathologies, none of which is found in more than 50% of couples after routine investigation...

journal_title：Current opinion in obstetrics & gynecology

authors： Tang AW,Quenby S

更新日期：2010-12-01 00:00:00

abstract：:During the period under review (December 1990 through January 1992), the revised World Health Organization Histological Classification of Ovarian Neoplasms and Tumor-like Lesions was completed, and it is presented herein. This system of classification incorporates recent advances and includes newly recognized entities...

journal_title：Current opinion in obstetrics & gynecology

authors： Talerman A

更新日期：1992-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To present the outcome of laparoscopic resection for bowel endometriosis. RECENT FINDINGS:In the last 12 months, numerous articles have been published to demonstrate and underline the efficiency and feasibility of the laparoscopic approach in the treatment of bowel endometriosis. SUMMARY:Endometrios...

journal_title：Current opinion in obstetrics & gynecology

authors： Ruffo G,Rossini R

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To avoid both overtreatment and undertreatment accurate risk assessment is mandatory. The present review gives an overview of recently published articles covering prognostic and predictive factors for adjuvant therapy in early breast cancer. RECENT FINDINGS:Gene expression signatures enhance prognost...

journal_title：Current opinion in obstetrics & gynecology

authors： Schmidt M

更新日期：2020-02-01 00:00:00

abstract：:The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Mahutte NG,Arici A

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Genetic variation plays a crucial role in modification of normal or disease pathophysiology. Follicle stimulating hormone receptor (FSHR) signaling is necessary for normal development and function of the ovaries and testes. Here, we review the associations between FSHR polymorphisms and fertility or s...

journal_title：Current opinion in obstetrics & gynecology

authors： Lalioti MD

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The review aims to summarize recent data about vascular endothelial growth factor and its implications in the normal endometrium during the menstrual cycle, implantation window and early pregnancy. RECENT FINDINGS:Angiogenesis is crucial for the development of endometrium as well as for embryo implan...

journal_title：Current opinion in obstetrics & gynecology

authors： Nardo LG

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight relevant strategies to overcome poly(ADP-ribose) polymerase (PARP) inhibitor resistance and present key clinical trials. RECENT FINDINGS:The use of PARP inhibition (PARPi) for frontline maintenance offers substantial clinical benefit in patients with homologous recombination-deficient tu...

journal_title：Current opinion in obstetrics & gynecology

authors： Hinchcliff E,Chelariu-Raicu A,Westin SN

更新日期：2021-02-01 00:00:00

abstract：:Doppler ultrasound velocimetry of uteroplacental, umbilical, and fetal vessels provides the clinician with important information on the hemodynamics of the vascular area under study. Transvaginal color Doppler is a new technique that allows precise investigation of fetomaternal circulation in early pregnancy. Doppler ...

journal_title：Current opinion in obstetrics & gynecology

authors： Kurjak A,Kupesic S,Zudenigo D

更新日期：1994-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aromatase inhibitors are increasingly used as adjuvant therapy in postmenopausal women with hormone receptor positive breast cancer. With additional experience using these agents, unanticipated side effects have become apparent. Women who experience side effects from adjuvant endocrine therapy are...

journal_title：Current opinion in obstetrics & gynecology

authors： Mortimer JE

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Much attention has been paid to the role of immunology in reproductive success or failure. Every step in the establishment of normal pregnancy has been implicated as a possible site of immune-mediated reproductive failure. The widespread testing of antiphospholipid, antinuclear, antithyroid, and antis...

journal_title：Current opinion in obstetrics & gynecology

authors： Kallen CB,Arici A

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to analyze what is known to date about the relation between telomeres and male fertility, and if it is possible for telomeres, or elements related to them, to be used as new prognostic biomarkers in fertility treatment. RECENT FINDINGS:Cells in germ series, including spe...

journal_title：Current opinion in obstetrics & gynecology

authors： Balmori C,Varela E

更新日期：2018-06-01 00:00:00

abstract：:Outpatient hysteroscopy has shown good correlation of findings compared with inpatient hysteroscopy, but one limitation is pain and discomfort in some women, and vasovagal reaction. Various forms of local anaesthesia have been evaluated in the past year, with controversial results, and a narrow 3.5 mm sheath hysterosc...

journal_title：Current opinion in obstetrics & gynecology

authors： Marana R,Marana E,Catalano GF

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:More than 50% of all gynecologic cancers can be classified as rare tumors (defined as an incidence of <6 per 100 000) and as such represent a major challenge for clinicians. RECENT FINDINGS:The rapidly increasing number of targeted therapies provides a unique opportunity to improve treatment options ...

journal_title：Current opinion in obstetrics & gynecology

authors： Ray-Coquard I,Pujade-Lauraine E,Ledermann JA

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutics targeting the ErbB protein family receptors have not always yielded favorable or successful results in present cancer therapy. This review discusses the possibility of the clinical adaptation of targeting against heparin-binding epidermal growth factor-like growth factor (HB-EGF), one of ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tsujioka H,Yotsumoto F,Hikita S,Ueda T,Kuroki M,Miyamoto S

更新日期：2011-02-01 00:00:00

abstract：:Early ectopic pregnancy screening using vaginal ultrasonographic technology together with measurement of beta human chorionic gonadotropin (beta-hCG) and human chorionic somatomammotropin is possible within the first 2 weeks of the missing menses, prior to the appearance of symptoms. This article summarizes the main a...

journal_title：Current opinion in obstetrics & gynecology

authors： Mettler L

更新日期：1991-06-01 00:00:00