Current controversies in traditional and expanded carrier screening.

abstract：PURPOSE OF REVIEW:Digital media, including the Internet, social networking sites, text messaging, and mobile applications, are ubiquitous among adolescents and young adults. These platforms enable users to obtain important information on a multitude of health topics, they may facilitate risk-taking behaviors, and they ...

journal_title：Current opinion in obstetrics & gynecology

authors： Gilliam M,Chor J,Hill B

更新日期：2014-10-01 00:00:00

abstract：:In the past year, new data have been published on the molecular biology of human papillomavirus infections and their relationship to cervical neoplasia. As molecular techniques have become more sophisticated and as the molecular knowledge of human papilloma-virus infections has been pursued in greater depth, it is inc...

journal_title：Current opinion in obstetrics & gynecology

authors： Richart RM,Wright TC Jr

更新日期：1992-10-01 00:00:00

abstract：:The advent of the AIDS epidemic coupled with enhanced recognition of the morbidity and mortality associated with occupationally acquired hepatitis B virus infection has resulted in a great interest in the epidemiologic characteristics of contact of surgical personnel with patient's blood and other bodily fluids in ass...

journal_title：Current opinion in obstetrics & gynecology

authors： Hemsell DL

更新日期：1993-06-01 00:00:00

abstract：:Urinary incontinence remains a common problem that adversely affects the quality of life of millions of women. In detrusor instability, treatment measures often lack efficacy or are accompanied by unacceptable side effects. In this review, standard treatments are discussed, together with recent pharmacologic advances ...

journal_title：Current opinion in obstetrics & gynecology

authors： Wise B,Cardozo L

更新日期：1991-08-01 00:00:00

abstract：:Recent publications about emergency and implantable contraception focused on increasing the awareness about emergency contraceptive methods and on updating readers about the controversies surrounding Norplant. Both emergency and implantable contraception have excellent safety and efficacy profiles, yet neither has rea...

journal_title：Current opinion in obstetrics & gynecology

authors： Cullins VE,Garcia FA

更新日期：1997-06-01 00:00:00

abstract：:Our understanding of the causes, mechanisms, and prenatal management of fetal obstructive uropathy has increased significantly. Improved methods of prenatal evaluation have allowed the better selection of fetuses for invasive therapy, and studies indicate better survival and renal outcomes in carefully selected cases....

journal_title：Current opinion in obstetrics & gynecology

authors： Johnson MP,Freedman AL

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Neonatal herpes simplex virus infection is often severe, if not fatal. What is our understanding of the epidemiology of this disease? How is it diagnosed? Would maternal screening for herpes simplex virus-2 (HSV-2) in pregnancy make a difference? Does maternal HSV alter transmission of HIV vertically ...

journal_title：Current opinion in obstetrics & gynecology

authors： Roberts S

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the latest developments in screening and diagnosis of non-chromosomal genetic diseases. RECENT FINDINGS:Major recent advances include the completion of the Human Genome Project, the use of microarray and related technologies for mass screening and diagnosis of thousands of genetic abnormali...

journal_title：Current opinion in obstetrics & gynecology

authors： Lau TK,Leung TN

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Borderline tumors of the ovary are seen commonly in obstetrics and gynecology practices. This review will outline the most recent information regarding the epidemiology, molecular pathogenesis, pathology, and clinical management of these tumors. RECENT FINDINGS:In the past, borderline ovarian tumors ...

journal_title：Current opinion in obstetrics & gynecology

authors： Crispens MA

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews new concepts in the aetiology of recurrent miscarriage, presents new outcome data and evaluates new modalities of treatment for unexplained recurrent miscarriage. RECENT FINDINGS:Preimplantation genetic diagnosis has been considered an option for couples who have structural chrom...

journal_title：Current opinion in obstetrics & gynecology

authors： Carrington B,Sacks G,Regan L

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate the impact of early pregnancy complications involving placentation and early placental development on adverse obstetric outcome in ongoing and subsequent pregnancies. RECENT FINDINGS:We found an increased risk of adverse outcome (odds ratio >2.0) in ongoing pregnancies of preterm delivery...

journal_title：Current opinion in obstetrics & gynecology

authors： Jauniaux E,Van Oppenraaij RH,Burton GJ

更新日期：2010-12-01 00:00:00

abstract：:Various malignant neoplasms, either primary or secondary, can affect the vagina. The most common primary malignant tumors of the vagina are squamous cell cancers; however, they are among the most uncommon of all primary gynecologic cancers. Vaginal intraepithelial neoplasia is being diagnosed with increasing frequency...

journal_title：Current opinion in obstetrics & gynecology

authors： Benedet JL

更新日期：1991-02-01 00:00:00

abstract：:Reflective of increasing attention to male sterilization are the development in China of the so-called "no scalpel" vasectomy technique, experiments with predicting reversibility through measurement of the cytometry of testicular aspirates, and research on issues such as the effects of vasectomy on spermatogenesis...

journal_title：Current opinion in obstetrics & gynecology

authors： Davis JE

更新日期：1990-08-01 00:00:00

abstract：:The obstetrician-gynecologist must assume a dual role in the future provision of health care to women. Not only should the obstetrician-gynecologist function as a consultant for medical and surgical problems peculiar to the female reproductive tract, but also assume a broader-based role for preventive medicine and hea...

journal_title：Current opinion in obstetrics & gynecology

authors： Laube DW

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Venous thromboembolism is the leading cause of maternal death in the UK. Thrombophilia underlies many thrombotic disorders in pregnancy. The high prevalence of thrombophilic defects in the population, the association of defects with venous thromboembolism and the special considerations for management ...

journal_title：Current opinion in obstetrics & gynecology

authors： Robertson L,Greer I

更新日期：2005-04-01 00:00:00

abstract：:The field of preimplantation genetic diagnosis has undergone significant advances since the report of the first birth from this method in 1990. The first birth in the USA was reported in 1992, as was the first successful diagnosis and delivery of a baby free of a single gene defect disorder (cystic fibrosis and then T...

journal_title：Current opinion in obstetrics & gynecology

authors： Grifo JA,Tang YX,Munne S,Krey L

更新日期：1996-04-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the techniques recently tested in both animal models and humans to provide a state-of-the-art on adult stem cell ovarian transplant to achieve ovarian rejuvenation in patients with diminished ovarian reserves. RECENT FINDINGS:As the firsts reports of spontaneous pregnancies achieved after b...

journal_title：Current opinion in obstetrics & gynecology

authors： Herraiz S,Pellicer N,Romeu M,Pellicer A

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article provides an overview of the molecular mechanisms underlying adolescent endometriosis and advances in both medical and surgical management. RECENT FINDINGS:Molecular and cellular features of endometriotic lesions differ from eutopic endometrium. There is altered estrogen-mediated c...

journal_title：Current opinion in obstetrics & gynecology

authors： Mama ST

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The past 15 years have seen a five-fold increase in the incidence of acquired heart disease as a cause of maternal mortality in the UK, and advances in the surgical correction of congenital heart disease have enabled many more women to survive childhood and present at the antenatal clinic. This review...

journal_title：Current opinion in obstetrics & gynecology

authors： Curry R,Swan L,Steer PJ

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to outline ovarian conservation and fertility sparing surgery (FSS) in the management of the most common pediatric gynecology malignancies. RECENT FINDINGS:Management of gynecologic malignancies has evolved to have a greater appreciation for adverse late effects from rad...

journal_title：Current opinion in obstetrics & gynecology

authors： Stambough K,Childress KJ

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:What controls puberty remains largely unknown and current gene mutations account for only about one-third of the apparently genetic cases of idiopathic hypogonadotropic hypogonadism. Lately important developments have occurred in this field. RECENT FINDINGS:Substantial variation in clinical expressio...

journal_title：Current opinion in obstetrics & gynecology

authors： Topaloglu AK,Kotan LD

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cervical cytology screening programs have dramatically decreased rates of invasive cancer in developed countries, most guidelines in the USA were overaggressive in their management of abnormal cytology in adolescents and young women. These management strategies resulted in costly over-treatme...

journal_title：Current opinion in obstetrics & gynecology

authors： Moscicki AB

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Noninvasive prenatal diagnosis for single gene disorders is coming to fruition in its clinical utility. The presence of cell-free DNA in maternal plasma has been recognized for many years, and a number of applications have developed from this. Noninvasive prenatal diagnosis for single gene disorders h...

journal_title：Current opinion in obstetrics & gynecology

authors： Allen S,Young E,Bowns B

更新日期：2017-04-01 00:00:00

abstract：:During the past few years enormous progress has been made in the understanding of the molecular mechanisms involved in parturition; however, the answer to the fundamental question of how labor is initiated remains elusive. This is a very important question because alterations in the timing of birth (preterm and post-t...

journal_title：Current opinion in obstetrics & gynecology

authors： Valenzuela GJ,Germain A,Foster TC

更新日期：1993-10-01 00:00:00

abstract：:This review explores some of the implications for a balanced approach to the ethics of maternal participation in clinical research, from the perspective of the fetus as a patient, which is a central concept in obstetric ethics. The review therefore begins with an account of this topic, followed by an examination of so...

journal_title：Current opinion in obstetrics & gynecology

authors： Chervenak FA,McCullough LB

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:As the life expectancy of cystic fibrosis (CF) patients continues to increase, and more patients become adults with a chronic disease, researching the impact of the disorder on male and female infertility has become increasingly important. Studies suggest that the prevalence of CF mutations may be hig...

journal_title：Current opinion in obstetrics & gynecology

authors： Ahmad A,Ahmed A,Patrizio P

更新日期：2013-06-01 00:00:00

abstract：:Outpatient hysteroscopy has shown good correlation of findings compared with inpatient hysteroscopy, but one limitation is pain and discomfort in some women, and vasovagal reaction. Various forms of local anaesthesia have been evaluated in the past year, with controversial results, and a narrow 3.5 mm sheath hysterosc...

journal_title：Current opinion in obstetrics & gynecology

authors： Marana R,Marana E,Catalano GF

更新日期：2001-08-01 00:00:00

abstract：:Human papillomavirus (HPV) infection and HPV-associated diseases pose a considerable health care burden in the United States. The morbidity and mortality associated with HPV infection and HPV-associated diseases, ranging from genital warts to cervical cancer, have prompted both the use of screening measures to monitor...

journal_title：Current opinion in obstetrics & gynecology

authors： Mayeaux EJ Jr

更新日期：2006-02-01 00:00:00

abstract：:Advances in perinatal and neonatal health care over the past few decades have resulted in a substantial reduction in perinatal mortality. Some of this improvement has been attributed to antepartum fetal surveillance techniques. The primary objective of antepartum fetal surveillance techniques is to avoid fetal deaths....

journal_title：Current opinion in obstetrics & gynecology

authors： Ananth CV,Smulian JC,Vintzileos AM

更新日期：1997-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To avoid both overtreatment and undertreatment accurate risk assessment is mandatory. The present review gives an overview of recently published articles covering prognostic and predictive factors for adjuvant therapy in early breast cancer. RECENT FINDINGS:Gene expression signatures enhance prognost...

journal_title：Current opinion in obstetrics & gynecology

authors： Schmidt M

更新日期：2020-02-01 00:00:00