Fertility, IVF and reproductive genetics.

abstract：PURPOSE OF REVIEW:The last several years have seen a number of important clinical and academic advances in long-acting reversible contraceptive (LARC) methods, such that many professional medical organizations now recommend these methods as first-line contraception for all women. RECENT FINDINGS:Recent data support th...

journal_title：Current opinion in obstetrics & gynecology

authors： Conti J,Shaw K

更新日期：2015-12-01 00:00:00

abstract：:Through the study of naturally occurring mutations in humans, the creation of mutations by site-directed mutagenesis, and the production of transgenic knockout mice, further understanding of molecular reproductive endocrinology had been achieved. Mutations in the aromatase gene in females have confirmed that its defic...

journal_title：Current opinion in obstetrics & gynecology

authors： Layman LC

更新日期：1995-10-01 00:00:00

abstract：:Our understanding of the causes, mechanisms, and prenatal management of fetal obstructive uropathy has increased significantly. Improved methods of prenatal evaluation have allowed the better selection of fetuses for invasive therapy, and studies indicate better survival and renal outcomes in carefully selected cases....

journal_title：Current opinion in obstetrics & gynecology

authors： Johnson MP,Freedman AL

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review is timely and relevant for several reasons. The incidence of adenomyosis begins to rise from the mid-thirties. Moreover, more women are delaying their first pregnancy until later in their thirties or forties, and consequently adenomyosis is encountered more frequently in the fertility clin...

journal_title：Current opinion in obstetrics & gynecology

authors： Matalliotakis IM,Katsikis IK,Panidis DK

更新日期：2005-06-01 00:00:00

abstract：:Studies published in the past year have attempted to model the pathophysiology of the twin-twin transfusion syndrome and also to establish the minimal diagnostic criteria for the condition. Many papers focused on treatment regimens and their sequelae. Aggressive treatment with serial amnioreduction continues to predom...

journal_title：Current opinion in obstetrics & gynecology

authors： Filkins KA,Beverly SE

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although developing countries have made much progress in expanding the availability and use of family planning services, the need for effective contraception is large, and growing because the largest cohorts in human history are entering their reproductive years. Not only regarding developing countrie...

journal_title：Current opinion in obstetrics & gynecology

authors： Cornet A

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The different patterns of autoreactivity that may account for the premature infertility observed in patients with premature ovarian failure are described. RECENT FINDINGS:Animal model studies have detailed fundamental immune dysregulatory patterns that induce ovarian failure in the context of global ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tuohy VK,Altuntas CZ

更新日期：2007-08-01 00:00:00

abstract：:Approximately 12 million women worldwide use the levonorgestrel-releasing intrauterine system (IUS), with approximately 180,000 users of this IUS currently reported in Austria. A patient satisfaction study of 591 women in Austria revealed a high number of 'very satisfied' (79%) and 'satisfied' (19%) patients. Reliabil...

journal_title：Current opinion in obstetrics & gynecology

authors： Concin H,Bösch H,Hintermüller P,Hohlweg T,Mursch-Edlmayr G,Pinnisch B,Schmidl-Amann S,Schulz-Greinwald G,Unterlerchner D,Wagner T,Mattle V,Wildt L,Fiala C

更新日期：2009-11-01 00:00:00

abstract：:Mifepristone is an orally active progesterone antagonist. It can be used for both contraceptive and non-contraceptive clinical indications. It is a very effective drug for emergency contraception with a low incidence of side effects. There is a potential for mifepristone to be used as a once-a-month pill. There is a n...

journal_title：Current opinion in obstetrics & gynecology

authors： Ho PC,Yu Ng EH,Tang OS

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Maternal mental health disorders, including anxiety and depression, are one of the most common obstetric complications, presenting in pregnancy and postpartum. RECENT FINDINGS:Maternal mental health disorders are associated with adverse maternal and neonatal outcomes. Screening women in pregnancy and...

journal_title：Current opinion in obstetrics & gynecology

authors： Yeaton-Massey A,Herrero T

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Traditionally, ovarian stimulation for IVF/intracytoplasmic sperm injection is performed by healthcare professionals, requiring the patient to make frequent visits to these centres. We describe the rationale, research findings and early clinical experience with home-based sonography for IVF patients. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Gerris J

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide clinicians with a review of recent research and clinically applicable tools regarding teen pregnancy. RECENT FINDINGS:Teen pregnancy rates have declined but still remain a significant problem in the USA. Teen pregnancy prevention was identified by Centers for Disease Control and Prevention...

journal_title：Current opinion in obstetrics & gynecology

authors： McCracken KA,Loveless M

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To avoid both overtreatment and undertreatment accurate risk assessment is mandatory. The present review gives an overview of recently published articles covering prognostic and predictive factors for adjuvant therapy in early breast cancer. RECENT FINDINGS:Gene expression signatures enhance prognost...

journal_title：Current opinion in obstetrics & gynecology

authors： Schmidt M

更新日期：2020-02-01 00:00:00

abstract：:Adolescent pregnancy and its consequences continue as major sources of morbidity in the United States. A teenager who becomes a parent is at a significant disadvantage in becoming a contributing adult, both psychosocially and economically. The physician who cares for adolescents has the responsibility of helping paren...

journal_title：Current opinion in obstetrics & gynecology

authors： Cromer BA,Brown RT

更新日期：1992-12-01 00:00:00

abstract：:Examination of the placenta may be viewed as a diary of the pregnancy. Apart from its immediate diagnostic value, it can also broadly serve two purposes: 1) it provides a method of auditing antenatal clinical judgment by clinicopathologic correlation, and 2) it makes an important contribution in the context of unsolve...

journal_title：Current opinion in obstetrics & gynecology

authors： Gillan JE

更新日期：1992-04-01 00:00:00

abstract：:Human papillomavirus testing has been evaluated as an adjunct to cervical cytologic screening. There is a well-established association between high-risk malignant subtypes of human papillomavirus infection and the development of neoplastic change. Although human papillomavirus infection is a necessary condition for ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Goodman A

更新日期：2000-02-01 00:00:00

abstract：:Child sexual abuse is being recognized as a common and serious problem which affects children regardless of their age, sex, socio-economic class, or geographic location. Children of all ages, from infancy to young adulthood, have been victims of abuse. It is well accepted that the number of reported incidents of child...

journal_title：Current opinion in obstetrics & gynecology

authors： Muram D

更新日期：1993-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Laparoscopy is the gold standard for the diagnosis of endometriosis but the need for visual evidence of the disease is a major stumbling-block for both effective clinical management of affected patients as well as for research into this common and debilitating reproductive disease. Laparoscopy is inva...

journal_title：Current opinion in obstetrics & gynecology

authors： Brosens I,Puttemans P,Campo R,Gordts S,Brosens J

更新日期：2003-12-01 00:00:00

abstract：:The field of preimplantation genetic diagnosis has undergone significant advances since the report of the first birth from this method in 1990. The first birth in the USA was reported in 1992, as was the first successful diagnosis and delivery of a baby free of a single gene defect disorder (cystic fibrosis and then T...

journal_title：Current opinion in obstetrics & gynecology

authors： Grifo JA,Tang YX,Munne S,Krey L

更新日期：1996-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Apart from histopathology, electrophysiological methods are the only tests to reveal neuromuscular involvement in the absence of gross anatomical lesions. They have played a major role in establishing the neuromuscular lesion due to vaginal delivery as a risk factor for incontinence and pelvic organ p...

journal_title：Current opinion in obstetrics & gynecology

authors： Vodusek DB

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current role of radiation therapy and specific types of radiation therapy used in the management of early stage, locoregionally advanced, and metastatic breast cancer. RECENT FINDINGS:The role of radiation therapy in the management of breast cancer has not changed in recent decades, h...

journal_title：Current opinion in obstetrics & gynecology

authors： McCloskey SA,Lee SP,Steinberg ML

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Genetic variation plays a crucial role in modification of normal or disease pathophysiology. Follicle stimulating hormone receptor (FSHR) signaling is necessary for normal development and function of the ovaries and testes. Here, we review the associations between FSHR polymorphisms and fertility or s...

journal_title：Current opinion in obstetrics & gynecology

authors： Lalioti MD

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Antiphospholipid syndrome (APS) is defined as the association of thrombotic events and/or obstetric morbidity in patients persistently positive for antiphospholipid antibodies (aPL). In this review, we will highlight the most important clinical presentations of APS with a focus on the obstetric morbid...

journal_title：Current opinion in obstetrics & gynecology

authors： Schreiber K,Radin M,Sciascia S

更新日期：2017-12-01 00:00:00

abstract：:The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Mahutte NG,Arici A

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article will review recent changes in the standard of care for olaparib, niraparib, and rucaparib, as well as ongoing trials evaluating this class of drugs in combination with antiangiogenic agents and PD-1/PD-L1 inhibitors. RECENT FINDINGS:Niraparib received FDA approval for use in patients wit...

journal_title：Current opinion in obstetrics & gynecology

authors： Washington CR,Moore KN

更新日期：2021-02-01 00:00:00

abstract：:In the past year, new data have been published on the molecular biology of human papillomavirus infections and their relationship to cervical neoplasia. As molecular techniques have become more sophisticated and as the molecular knowledge of human papilloma-virus infections has been pursued in greater depth, it is inc...

journal_title：Current opinion in obstetrics & gynecology

authors： Richart RM,Wright TC Jr

更新日期：1992-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Immune checkpoint blockade (ICB) is a promising area of cancer therapeutic research. Therapies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) mechanism of tumor immune evasion have resulted in durable responses in many difficult-to-treat tumor types. While these...

journal_title：Current opinion in obstetrics & gynecology

authors： Chin CD,Fares CM,Konecny GE,Rao J

更新日期：2020-02-01 00:00:00

abstract：:Few randomized studies have addressed the best choice of adjuvant radiation therapy after surgery for stage I endometrial cancer. Although whole pelvic radiation decreases the incidence of pelvic and vaginal cancer recurrence, there is no convincing evidence that it improves survival in women who have been completely ...

journal_title：Current opinion in obstetrics & gynecology

authors： Naumann RW

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Understanding the cause of tubal ectopic pregnancy (tEP) remains incomplete. We aim to summarize the latest advances in laboratory models of tEP that we believe will, ultimately, contribute to improving the diagnosis and management of the condition. RECENT FINDINGS:Progress in proteome prefractionati...

journal_title：Current opinion in obstetrics & gynecology

authors： Brown JK,Horne AW

更新日期：2011-08-01 00:00:00

abstract：:Ovarian stimulation is applied during infertility management either alone or in conjunction with intrauterine insemination and assisted reproductive technologies. At the present time, the two main medications used for ovarian stimulation include an oral antiestrogen, clomiphene citrate, and injectable gonadotropins. I...

journal_title：Current opinion in obstetrics & gynecology

authors： Mitwally MF,Casper RF

更新日期：2002-06-01 00:00:00