Managing symptoms and maximizing quality of life after preventive interventions for cancer risk reduction.

abstract：PURPOSE OF REVIEW:What controls puberty remains largely unknown and current gene mutations account for only about one-third of the apparently genetic cases of idiopathic hypogonadotropic hypogonadism. Lately important developments have occurred in this field. RECENT FINDINGS:Substantial variation in clinical expressio...

journal_title：Current opinion in obstetrics & gynecology

authors： Topaloglu AK,Kotan LD

更新日期：2010-08-01 00:00:00

abstract：:This review explores some of the implications for a balanced approach to the ethics of maternal participation in clinical research, from the perspective of the fetus as a patient, which is a central concept in obstetric ethics. The review therefore begins with an account of this topic, followed by an examination of so...

journal_title：Current opinion in obstetrics & gynecology

authors： Chervenak FA,McCullough LB

更新日期：1999-12-01 00:00:00

abstract：:The proper use of forceps or vacuum extractor, or both, remains a safe and effective modality in achieving the universal goal of a healthy mother and baby. Their use requires continued experience, sharing of information, and possibly attention to subtleties of design. This review looks at the current situation with sp...

journal_title：Current opinion in obstetrics & gynecology

authors： Robinson JC

更新日期：1994-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Immune checkpoint blockade (ICB) is a promising area of cancer therapeutic research. Therapies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) mechanism of tumor immune evasion have resulted in durable responses in many difficult-to-treat tumor types. While these...

journal_title：Current opinion in obstetrics & gynecology

authors： Chin CD,Fares CM,Konecny GE,Rao J

更新日期：2020-02-01 00:00:00

abstract：:Many different disease processes can result in a phenotype of hirsutism, anovulation, and oligomenorrhea or amenorrhea. An important goal of reproductive endocrinologists is to identify specific genetic diseases that can produce the hyperandrogenic phenotype. Two genetic disorders that can result in the hyperandrogeni...

journal_title：Current opinion in obstetrics & gynecology

authors： Barbieri RL

更新日期：1991-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The different patterns of autoreactivity that may account for the premature infertility observed in patients with premature ovarian failure are described. RECENT FINDINGS:Animal model studies have detailed fundamental immune dysregulatory patterns that induce ovarian failure in the context of global ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tuohy VK,Altuntas CZ

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Thyroid disorders are common in pregnancy and affect maternal and fetal outcome. RECENT FINDINGS:The reference values for normal thyroid function during first and second trimester had been re-evaluated recently. Hypothyroxinemia affects the neuropsychological development of the child. Maternal thyroi...

journal_title：Current opinion in obstetrics & gynecology

authors： Gärtner R

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the beneficial effects of micronutrient supplementation on male fertility. RECENT FINDINGS:Several micronutrients have beneficial effects on sperm quality, as well on male fertility (e.g. pregnancy rate). A deliberate use of micronutrients might be helpful for infertile patients. Healthca...

journal_title：Current opinion in obstetrics & gynecology

authors： Buhling KJ,Laakmann E

更新日期：2014-06-01 00:00:00

abstract：:An increasing number of diseases in child and adult life are now thought to have their origins in the fetal period. Central to this predisposition is restriction of fetal growth. During the period reviewed in this article, the associations between adult hypertension and low birthweight were confirmed, and numerous stu...

journal_title：Current opinion in obstetrics & gynecology

authors： Newnham J

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses recently published data concerning the anabolic effects of androgens on muscle and the mechanism by which testosterone regulates body composition with special emphasis on the anabolic effects of androgens on the muscles of the pelvic floor and lower urinary tract. RECENT FINDING...

journal_title：Current opinion in obstetrics & gynecology

authors： Ho MH,Bhatia NN,Bhasin S

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Polycystic ovary syndrome is one of the most common endocrinopathies affecting premenopausal women. This review focuses on this major cause of hyperandrogenism in adolescents and young women, highlighting new diagnostic and therapeutic strategies that are under investigation. The pathophysiologic role...

journal_title：Current opinion in obstetrics & gynecology

authors： Stafford DE,Gordon CM

更新日期：2002-10-01 00:00:00

abstract：:Ultrasound prenatal diagnosis of structural anomalies has become almost a separate branch of obstetrics. The advantages of performing ultrasound in pregnancies at high risk for fetal structural anomalies are clear. Patients and the news media have placed ever-increasing expectations on persons performing diagnostic ul...

journal_title：Current opinion in obstetrics & gynecology

authors： Gomez KJ,Copel JA

更新日期：1993-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutics targeting the ErbB protein family receptors have not always yielded favorable or successful results in present cancer therapy. This review discusses the possibility of the clinical adaptation of targeting against heparin-binding epidermal growth factor-like growth factor (HB-EGF), one of ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tsujioka H,Yotsumoto F,Hikita S,Ueda T,Kuroki M,Miyamoto S

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review current available literature on the relationship between fibroids and infertility with particular emphasis on the benefits of myomectomy. Pregnancy complications related to the presence of these lesions and to their removal are also addressed. RECENT FINDINGS:There is a biological plausibil...

journal_title：Current opinion in obstetrics & gynecology

authors： Somigliana E,Vercellini P,Benaglia L,Abbiati A,Barbara G,Fedele L

更新日期：2008-08-01 00:00:00

abstract：:Selective oestrogen receptor modulators are a range of compounds which mimic some, but not all, agonist actions of oestrogen in different tissues. They were developed with the aim of maximizing the benefits of oestrogen-like drugs in a number of important conditions whilst reducing adverse side-effects. The molecular ...

journal_title：Current opinion in obstetrics & gynecology

authors： Baynes KC,Compston JE

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:With over 50 million abortions annually and 25% of pregnancies ending in abortion worldwide, abortion is one of the most common medical procedures. Yet abortion-related topics are glaringly absent from medical school curricula in the USA with half of medical schools including no formal training or onl...

journal_title：Current opinion in obstetrics & gynecology

authors： Burns RM,Shaw KA

更新日期：2020-12-01 00:00:00

abstract：:The advent of the AIDS epidemic coupled with enhanced recognition of the morbidity and mortality associated with occupationally acquired hepatitis B virus infection has resulted in a great interest in the epidemiologic characteristics of contact of surgical personnel with patient's blood and other bodily fluids in ass...

journal_title：Current opinion in obstetrics & gynecology

authors： Hemsell DL

更新日期：1993-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Amidst the worldwide coronavirus disease 2019 pandemic, a new medical landscape revolving around telemedicine has arisen. The purpose of this review is to describe and analyze current urogynecologic guidelines for optimizing usage of telemedicine when treating women with pelvic floor disorders. RECEN...

journal_title：Current opinion in obstetrics & gynecology

authors： Serna-Gallegos T,Ninivaggio CS

更新日期：2020-12-01 00:00:00

abstract：:Examination of the placenta may be viewed as a diary of the pregnancy. Apart from its immediate diagnostic value, it can also broadly serve two purposes: 1) it provides a method of auditing antenatal clinical judgment by clinicopathologic correlation, and 2) it makes an important contribution in the context of unsolve...

journal_title：Current opinion in obstetrics & gynecology

authors： Gillan JE

更新日期：1992-04-01 00:00:00

abstract：:Recent publications about emergency and implantable contraception focused on increasing the awareness about emergency contraceptive methods and on updating readers about the controversies surrounding Norplant. Both emergency and implantable contraception have excellent safety and efficacy profiles, yet neither has rea...

journal_title：Current opinion in obstetrics & gynecology

authors： Cullins VE,Garcia FA

更新日期：1997-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Traditionally, ovarian stimulation for IVF/intracytoplasmic sperm injection is performed by healthcare professionals, requiring the patient to make frequent visits to these centres. We describe the rationale, research findings and early clinical experience with home-based sonography for IVF patients. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Gerris J

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence-based women's healthcare is underpinned by systematic reviews and guidelines. Generating an evidence synthesis to support guidance for clinical practice is a time-consuming and labour-intensive activity that delays transfer of research into practice. Artificial intelligence has the potential ...

journal_title：Current opinion in obstetrics & gynecology

authors： Amezcua-Prieto C,Fernández-Luna JM,Huete-Guadix JF,Bueno-Cavanillas A,Khan KS

更新日期：2020-10-01 00:00:00

abstract：:Transvaginal ultrasonography is emerging as the newest method for the early detection of structural malformations and markers of chromosomal aberrations. According to a multicenter registry on the onset of fetal anomalies, many defects are potentially detectable at an early transvaginal scan. Moreover, cystic hygroma ...

journal_title：Current opinion in obstetrics & gynecology

authors： Rottem S

更新日期：1995-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Endometriosis is a frequent gynaecological disorder in young women. Colorectal endometriosis accounts for about 90% of all intestinal locations. The effectiveness of medical therapies is poor, and surgery, including colorectal resection, is therefore often required. Since the first description of lapa...

journal_title：Current opinion in obstetrics & gynecology

authors： Daraï E,Bazot M,Rouzier R,Houry S,Dubernard G

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lazarin GA,Goldberg JD

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight relevant strategies to overcome poly(ADP-ribose) polymerase (PARP) inhibitor resistance and present key clinical trials. RECENT FINDINGS:The use of PARP inhibition (PARPi) for frontline maintenance offers substantial clinical benefit in patients with homologous recombination-deficient tu...

journal_title：Current opinion in obstetrics & gynecology

authors： Hinchcliff E,Chelariu-Raicu A,Westin SN

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances in oocyte and embryo cryopreservation techniques and outcomes. RECENT FINDINGS:Vitrification is gradually replacing slow freezing due to a better survival rate after thawing. Most units use vitrification for both oocyte and blastocyst cryopreservation, as these two biolog...

journal_title：Current opinion in obstetrics & gynecology

authors： Herrero L,Martínez M,Garcia-Velasco JA

更新日期：2011-08-01 00:00:00

abstract：:Current studies verify the safety of surgery in the elderly. Delirium is a costly complication, but its incidence and severity can be reduced by pre- and postoperative interventions. Avoidance of even mild hypothermia has now been shown to reduce cardiovascular morbidity. New information available on the cardiovascula...

journal_title：Current opinion in obstetrics & gynecology

authors： Miller KL

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been increasing interest in developing assisted reproductive technologies to overcome failure at fertilization and early embryonic arrest. Some of the affected patients harbor too few copies of mitochondrial DNA (mtDNA) in their eggs at the time of fertilization, which results in development...

journal_title：Current opinion in obstetrics & gynecology

authors： St John JC,Tsai TS,Cagnone GL

更新日期：2016-06-01 00:00:00

abstract：:The surgical management of hydrosalpinges is a controversial subject. Chronic pathology of the fallopian tube with distal obstruction leads to the formation of a hydrosalpinx, and is associated with very poor pregnancy rates after surgery. In these cases, in-vitro fertilization has proved to be a much better alternati...

journal_title：Current opinion in obstetrics & gynecology

authors： Mansour R,Aboulghar M,Serour GI

更新日期：2000-08-01 00:00:00