Cryopreservation of human embryos and oocytes.

Abstract:

:Human embryo cryopreservation is now a fully established adjunct to assisted reproduction, with thawed embryos implanting at a rate approaching that of fresh embryos. As with fresh embryos, the quality of frozen-thawed embryos is affected by patient age at the time of oocyte retrieval, and by culture conditions. Ovarian stimulation incorporating gonadotropin-releasing hormone analogs does not appear to be detrimental to cryopreservation success, and natural or artificial thaw cycles seem equally effective. Successful cryopreservation seems feasible for one- to eight-cell embryos and blastocysts using a variety of protocols. Selection criteria for embryos to be frozen can vary, and embryo quality has the most significant impact on post-cryopreservation viability. Unfertilized oocyte cryopreservation is coming closer to routine clinical application.

authors

Tucker MJ,Morton PC,Sweitzer CL,Wright G

doi

10.1097/00001703-199506000-00006

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

188-92

issue

3

eissn

1040-872X

issn

1473-656X

journal_volume

7

pub_type

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