Modern management of vulvar cancer.

abstract：PURPOSE OF REVIEW:Evidence-based women's healthcare is underpinned by systematic reviews and guidelines. Generating an evidence synthesis to support guidance for clinical practice is a time-consuming and labour-intensive activity that delays transfer of research into practice. Artificial intelligence has the potential ...

journal_title：Current opinion in obstetrics & gynecology

authors： Amezcua-Prieto C,Fernández-Luna JM,Huete-Guadix JF,Bueno-Cavanillas A,Khan KS

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:More than 50% of all gynecologic cancers can be classified as rare tumors (defined as an incidence of <6 per 100 000) and as such represent a major challenge for clinicians. RECENT FINDINGS:The rapidly increasing number of targeted therapies provides a unique opportunity to improve treatment options ...

journal_title：Current opinion in obstetrics & gynecology

authors： Ray-Coquard I,Pujade-Lauraine E,Ledermann JA

更新日期：2015-02-01 00:00:00

abstract：:Acquired immunodeficiency virus infections had recently been the leading cause of death in minority women of reproductive age in several urban cities in the United States. In addition, more than 80% of infants with human immunodeficiency virus type 1 infection acquired the infection perinatally. These alarming data ha...

journal_title：Current opinion in obstetrics & gynecology

authors： Sison AV

更新日期：1992-02-01 00:00:00

abstract：:We have attempted to review the best available evidence for the commonest gynaecological endoscopic procedures. Controlled studies are the exception rather than the rule, and randomized studies are even rarer. Therefore, the results of large, uncontrolled series must be acknowledged. As a result, for most procedures, ...

journal_title：Current opinion in obstetrics & gynecology

authors： Nagele F,Molnár BG,O'Connor H,Magos AL

更新日期：1996-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize results from the Women's Health Initiative trial and other recent randomized placebo-controlled trials of hormone replacement therapy, which fundamentally changed our understanding of its risks and benefits. RECENT FINDINGS:The Women's Health Initiative study for the first time provided ...

journal_title：Current opinion in obstetrics & gynecology

authors： Kocjan T,Prelevic GM

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The development of robotic technology has facilitated the application of minimally invasive techniques for complex operations in gynecologic oncology. The objective of this article is to review the published literature regarding robotic surgery and its application to gynecologic cancer. RECENT FINDIN...

journal_title：Current opinion in obstetrics & gynecology

authors： Yim GW,Kim YT

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Spontaneous preterm birth complicates 3-11% of pregnancies and is a major cause of neonatal mortality and morbidity worldwide. If accurate tests can be identified, a potentially effective screening strategy with an adjunct preventive therapy may be trialled to reduce the rate of spontaneous preterm bi...

journal_title：Current opinion in obstetrics & gynecology

authors： Honest H,Hyde CJ,Khan KS

更新日期：2012-12-01 00:00:00

abstract：:Gynecologic oncology is a rapidly growing field due to constant advances in immunohistochemistry and molecular biology. This review serves as an overview of new studies promoting the use of tumor markers and molecular biological prognostic factors in malignancies affecting women. The majority of studies focus on eithe...

journal_title：Current opinion in obstetrics & gynecology

authors： Geisler JP,Geisler HE

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Fetal magnetic resonance imaging (MRI) is a relatively new clinical application but is becoming increasingly used in fetal medicine in combination with the established technique of antenatal ultrasound. A review of the literature to date provides information for clinicians to help assess which patient...

journal_title：Current opinion in obstetrics & gynecology

authors： Rutherford MA

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances in oocyte and embryo cryopreservation techniques and outcomes. RECENT FINDINGS:Vitrification is gradually replacing slow freezing due to a better survival rate after thawing. Most units use vitrification for both oocyte and blastocyst cryopreservation, as these two biolog...

journal_title：Current opinion in obstetrics & gynecology

authors： Herrero L,Martínez M,Garcia-Velasco JA

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The different patterns of autoreactivity that may account for the premature infertility observed in patients with premature ovarian failure are described. RECENT FINDINGS:Animal model studies have detailed fundamental immune dysregulatory patterns that induce ovarian failure in the context of global ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tuohy VK,Altuntas CZ

更新日期：2007-08-01 00:00:00

abstract：:An increasing number of diseases in child and adult life are now thought to have their origins in the fetal period. Central to this predisposition is restriction of fetal growth. During the period reviewed in this article, the associations between adult hypertension and low birthweight were confirmed, and numerous stu...

journal_title：Current opinion in obstetrics & gynecology

authors： Newnham J

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review minimally invasive modifications of traditional surgeries for female stress urinary incontinence (SUI) in light of increased demand. RECENT FINDINGS:Prior to the synthetic mid-urethral sling (MUS), traditional procedures were used to correct SUI. Often these were retropubic colposuspension ...

journal_title：Current opinion in obstetrics & gynecology

authors： Shaw JS

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Fetal magnetic resonance imaging is becoming more used in the evaluation of complex fetal abnormalities. Rapid advances in the technology and application of fetal magnetic resonance imaging necessitate a review of this subject. RECENT FINDINGS:Diffusion-weighted imaging, magnetic resonance spectrosco...

journal_title：Current opinion in obstetrics & gynecology

authors： Sandrasegaran K,Lall CG,Aisen AA

更新日期：2006-12-01 00:00:00

abstract：:Doppler ultrasound velocimetry of uteroplacental, umbilical, and fetal vessels provides the clinician with important information on the hemodynamics of the vascular area under study. Transvaginal color Doppler is a new technique that allows precise investigation of fetomaternal circulation in early pregnancy. Doppler ...

journal_title：Current opinion in obstetrics & gynecology

authors： Kurjak A,Kupesic S,Zudenigo D

更新日期：1994-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical utility of sperm DNA fragmentation tests needs to be revisited in light of increasing evidence of detrimental effect of sperm DNA damage on reproductive outcomes. RECENT FINDINGS:Current evidence supports the association between high sperm DNA fragmentation and poor outcomes with regards...

journal_title：Current opinion in obstetrics & gynecology

authors： Agarwal A,Cho CL,Esteves SC

更新日期：2016-06-01 00:00:00

abstract：:The subdermal contraceptive implant etonogestrel (Implanon; NV Organon International, Oss, The Netherlands) exerts complex effects on the endometrium. These include direct effects on the endometrium through endometrial progestin target sites, and indirect effects through suppression of the hypothalamic-pituitary-ovari...

journal_title：Current opinion in obstetrics & gynecology

authors： Varma R,Mascarenhas L

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review is timely and relevant for several reasons. The incidence of adenomyosis begins to rise from the mid-thirties. Moreover, more women are delaying their first pregnancy until later in their thirties or forties, and consequently adenomyosis is encountered more frequently in the fertility clin...

journal_title：Current opinion in obstetrics & gynecology

authors： Matalliotakis IM,Katsikis IK,Panidis DK

更新日期：2005-06-01 00:00:00

abstract：:This review explores the recent experience with, and the basis for, the use of selective estrogen receptor modulators to treat and prevent breast cancer. As new agents are unveiled, they will continue to be tested against tamoxifen. A number of new selective estrogen receptor modulators are in clinical development in ...

journal_title：Current opinion in obstetrics & gynecology

authors： Bentrem DJ,Jordan VC

更新日期：2002-02-01 00:00:00

abstract：:The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Mahutte NG,Arici A

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the beneficial effects of micronutrient supplementation on male fertility. RECENT FINDINGS:Several micronutrients have beneficial effects on sperm quality, as well on male fertility (e.g. pregnancy rate). A deliberate use of micronutrients might be helpful for infertile patients. Healthca...

journal_title：Current opinion in obstetrics & gynecology

authors： Buhling KJ,Laakmann E

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:As the life expectancy of cystic fibrosis (CF) patients continues to increase, and more patients become adults with a chronic disease, researching the impact of the disorder on male and female infertility has become increasingly important. Studies suggest that the prevalence of CF mutations may be hig...

journal_title：Current opinion in obstetrics & gynecology

authors： Ahmad A,Ahmed A,Patrizio P

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Genetic variation plays a crucial role in modification of normal or disease pathophysiology. Follicle stimulating hormone receptor (FSHR) signaling is necessary for normal development and function of the ovaries and testes. Here, we review the associations between FSHR polymorphisms and fertility or s...

journal_title：Current opinion in obstetrics & gynecology

authors： Lalioti MD

更新日期：2011-06-01 00:00:00

abstract：:Outpatient hysteroscopy has shown good correlation of findings compared with inpatient hysteroscopy, but one limitation is pain and discomfort in some women, and vasovagal reaction. Various forms of local anaesthesia have been evaluated in the past year, with controversial results, and a narrow 3.5 mm sheath hysterosc...

journal_title：Current opinion in obstetrics & gynecology

authors： Marana R,Marana E,Catalano GF

更新日期：2001-08-01 00:00:00

abstract：:The management of advanced ovarian cancer relies on appropriate surgical cytoreduction in conjunction with appropriate adjuvant chemotherapy. In the past year several studies have continued to support aggressive cytoreduction at the initial operation, including for stage IV disease, as well as in a second-look setting...

journal_title：Current opinion in obstetrics & gynecology

authors： Chen LM,Berek JS

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of recent research and guidelines regarding contraception and breastfeeding. RECENT FINDINGS:Recent studies assessed lactogenesis, breastfeeding rates, and milk supply concerns in patients starting postpartum hormonal contraception. One study showed a small but statistically si...

journal_title：Current opinion in obstetrics & gynecology

authors： Stanton TA,Blumenthal PD

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article provides an overview of the molecular mechanisms underlying adolescent endometriosis and advances in both medical and surgical management. RECENT FINDINGS:Molecular and cellular features of endometriotic lesions differ from eutopic endometrium. There is altered estrogen-mediated c...

journal_title：Current opinion in obstetrics & gynecology

authors： Mama ST

更新日期：2018-10-01 00:00:00

abstract：:The past year has seen major challenges to existing maternal serum alpha-fetoprotein testing protocols for both neural tube defects and chromosomal anomalies. These challenges are reviewed along with the physiology of alpha-fetoprotein; the use of amniocentesis, ultrasonography, and additional serum markers in women w...

journal_title：Current opinion in obstetrics & gynecology

authors： Drugan A,Dvorin E,Obrien JE,Johnson MP,Evans MI

更新日期：1991-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Thyroid disorders are common in pregnancy and affect maternal and fetal outcome. RECENT FINDINGS:The reference values for normal thyroid function during first and second trimester had been re-evaluated recently. Hypothyroxinemia affects the neuropsychological development of the child. Maternal thyroi...

journal_title：Current opinion in obstetrics & gynecology

authors： Gärtner R

更新日期：2009-12-01 00:00:00

abstract：:The use of gonadotropin-releasing hormone agonists as adjunctive therapy with gonadotropins for ovulation induction in in vitro fertilization and other assisted reproductive technologies has become common clinical practice. With the recent advent of potent gonadotropin-releasing hormone antagonists free from the marke...

journal_title：Current opinion in obstetrics & gynecology

authors： Gordon K,Danforth DR,Williams RF,Hodgen GD

更新日期：1992-10-01 00:00:00