Abstract：
PURPOSE OF REVIEW:Spontaneous preterm birth complicates 3-11% of pregnancies and is a major cause of neonatal mortality and morbidity worldwide. If accurate tests can be identified, a potentially effective screening strategy with an adjunct preventive therapy may be trialled to reduce the rate of spontaneous preterm birth or effective measures be deployed at an early stage of a suspected spontaneous preterm labour before the onset of cervical changes to ameliorate prematurity complications. RECENT FINDINGS:There are many tests predicting spontaneous preterm births, published in the literature individually or in a systematic review. The information has not been collated about all candidate tests simultaneously in a systematic review incorporating a framework on how these tests may be evaluated, modelled with an intervention to provide a number needed to treat and test to inform decision-making. SUMMARY:There were 319 studies evaluating 22 tests. There are many promising tests, for example, history of previous spontaneous preterm birth, cervicovaginal swabs for markers such as fibronectin or HCG, cervical ultrasound, serum CRP and amniotic fluid interleukins for predicting spontaneous preterm birth, but none have exceptional accuracy and the quality of studies was generally poor. Some tests were able to achieve high LR+, but at the expense of LR-, that is, tests good for ruling in disease were poor for ruling out disease and vice versa.
journal_name
Curr Opin Obstet Gynecoljournal_title
Current opinion in obstetrics & gynecologyauthors
Honest H,Hyde CJ,Khan KSdoi
10.1097/GCO.0b013e328359823asubject
Has Abstractpub_date
2012-12-01 00:00:00pages
422-33issue
6eissn
1040-872Xissn
1473-656Xjournal_volume
24pub_type
杂志文章abstract：PURPOSE OF REVIEW:To describe the current consensus regarding the modern management of ovarian endometriosis and summarize the recent evidence that led to a shift in the management recommendations. RECENT FINDINGS:The vast majority of the recent studies demonstrate an adverse effect of surgery on ovarian reserve marke...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000078
更新日期：2014-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Prolonged (postterm) pregnancies are associated with both fetal and maternal complications. A variety of management practices can be utilized to mitigate the risk of these complications. RECENT FINDINGS:In addition to routine induction of labor at 41 weeks, a number of alternative management strategi...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/gco.0b013e328314b6f8
更新日期：2008-12-01 00:00:00
abstract：:In the past decade, neoadjuvant and concomitant multimodality therapies have been studied in patients with cervical cancer. The past year has witnessed more pilot studies confirming the feasibility of multimodality therapy. It is now time to move to prospective randomized clinical trials to determine the effects on di...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1993-02-01 00:00:00
abstract：:Through the study of naturally occurring mutations in humans, the creation of mutations by site-directed mutagenesis, and the production of transgenic knockout mice, further understanding of molecular reproductive endocrinology had been achieved. Mutations in the aromatase gene in females have confirmed that its defic...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：:Recent publications about emergency and implantable contraception focused on increasing the awareness about emergency contraceptive methods and on updating readers about the controversies surrounding Norplant. Both emergency and implantable contraception have excellent safety and efficacy profiles, yet neither has rea...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1997-06-01 00:00:00
abstract：:Ovarian stimulation is applied during infertility management either alone or in conjunction with intrauterine insemination and assisted reproductive technologies. At the present time, the two main medications used for ovarian stimulation include an oral antiestrogen, clomiphene citrate, and injectable gonadotropins. I...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-200206000-00003
更新日期：2002-06-01 00:00:00
abstract：:We have attempted to review the best available evidence for the commonest gynaecological endoscopic procedures. Controlled studies are the exception rather than the rule, and randomized studies are even rarer. Therefore, the results of large, uncontrolled series must be acknowledged. As a result, for most procedures, ...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1996-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Abortion services are essential in sexual and reproductive health and should be held to the same standards as other health services. Patient (or person)-centeredness is a key dimension of healthcare quality that incorporates the perspectives of patients in care provision. The purpose of this review is...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000492
更新日期：2018-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Polycystic ovary syndrome is one of the most common endocrinopathies affecting premenopausal women. This review focuses on this major cause of hyperandrogenism in adolescents and young women, highlighting new diagnostic and therapeutic strategies that are under investigation. The pathophysiologic role...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-200210000-00002
更新日期：2002-10-01 00:00:00
abstract：PURPOSE OF REVIEW:Although there is effective screening for cervical cancer, it continues to be a healthcare problem in developing countries. To increase survival rates, different strategies with neoadjuvant chemotherapy have been developed. Nearly all trials that analysed neoadjuvant chemotherapy plus surgery demonstr...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-200502000-00008
更新日期：2005-02-01 00:00:00
abstract：:Examination of the placenta may be viewed as a diary of the pregnancy. Apart from its immediate diagnostic value, it can also broadly serve two purposes: 1) it provides a method of auditing antenatal clinical judgment by clinicopathologic correlation, and 2) it makes an important contribution in the context of unsolve...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Antiphospholipid syndrome (APS) is defined as the association of thrombotic events and/or obstetric morbidity in patients persistently positive for antiphospholipid antibodies (aPL). In this review, we will highlight the most important clinical presentations of APS with a focus on the obstetric morbid...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000406
更新日期：2017-12-01 00:00:00
abstract：:Magnetic resonance imaging represents a new method of imaging the pelvic viscera and pelvic floor musculature. Rapid sequences allow us to perform magnetic resonance imaging dynamically during straining or pelvic floor contraction, which can elegantly demonstrate the patterns of pelvic floor prolapse. The technique is...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-199808000-00003
更新日期：1998-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Evidence-based women's healthcare is underpinned by systematic reviews and guidelines. Generating an evidence synthesis to support guidance for clinical practice is a time-consuming and labour-intensive activity that delays transfer of research into practice. Artificial intelligence has the potential ...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章
doi：10.1097/GCO.0000000000000643
更新日期：2020-10-01 00:00:00
abstract：PURPOSE OF REVIEW:There is persisting controversy about tocolytic treatment for preterm labour. This review addresses this controversy by appraising the recent clinical literature. RECENT FINDINGS:Surveys of obstetricians indicate a high usage of tocolysis for preterm labour, but evidence that this treatment confers o...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-200412000-00004
更新日期：2004-12-01 00:00:00
abstract：PURPOSE OF REVIEW:To describe the current role of radiation therapy and specific types of radiation therapy used in the management of early stage, locoregionally advanced, and metastatic breast cancer. RECENT FINDINGS:The role of radiation therapy in the management of breast cancer has not changed in recent decades, h...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0b013e3283425401
更新日期：2011-02-01 00:00:00
abstract：:In the past year, new data have been published on the molecular biology of human papillomavirus infections and their relationship to cervical neoplasia. As molecular techniques have become more sophisticated and as the molecular knowledge of human papilloma-virus infections has been pursued in greater depth, it is inc...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：PURPOSE OF REVIEW:To provide clinicians with a review of recent research and clinically applicable tools regarding teen pregnancy. RECENT FINDINGS:Teen pregnancy rates have declined but still remain a significant problem in the USA. Teen pregnancy prevention was identified by Centers for Disease Control and Prevention...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000102
更新日期：2014-10-01 00:00:00
abstract：:This review explores some of the implications for a balanced approach to the ethics of maternal participation in clinical research, from the perspective of the fetus as a patient, which is a central concept in obstetric ethics. The review therefore begins with an account of this topic, followed by an examination of so...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-199912000-00002
更新日期：1999-12-01 00:00:00
abstract：PURPOSE OF REVIEW:To describe the beneficial effects of micronutrient supplementation on male fertility. RECENT FINDINGS:Several micronutrients have beneficial effects on sperm quality, as well on male fertility (e.g. pregnancy rate). A deliberate use of micronutrients might be helpful for infertile patients. Healthca...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000063
更新日期：2014-06-01 00:00:00
abstract：PURPOSE OF REVIEW:The aim of this review is to summarize the current evidence on the safety and effectiveness of moving oral contraceptives from prescription-only to over-the-counter (OTC) status. The review also examines women's interest in OTC access to oral contraceptives, as well as potential barriers and facilitat...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000019
更新日期：2013-12-01 00:00:00
abstract：:The past year has seen major challenges to existing maternal serum alpha-fetoprotein testing protocols for both neural tube defects and chromosomal anomalies. These challenges are reviewed along with the physiology of alpha-fetoprotein; the use of amniocentesis, ultrasonography, and additional serum markers in women w...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Venous thromboembolism is the leading cause of maternal death in the UK. Thrombophilia underlies many thrombotic disorders in pregnancy. The high prevalence of thrombophilic defects in the population, the association of defects with venous thromboembolism and the special considerations for management ...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/01.gco.0000162177.30607.59
更新日期：2005-04-01 00:00:00
abstract：:Treatment of invasive vulvar malignancy has become more individualized during the past decade. In the past, radical vulvectomy with bilateral inguinofemoral lymphadenectomy was the standard therapy for invasive squamous cell carcinoma and melanoma of the vulva. This is no longer always the case. The treatment of stage...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1991-02-01 00:00:00
abstract：PURPOSE OF REVIEW:Fetal magnetic resonance imaging (MRI) is a relatively new clinical application but is becoming increasingly used in fetal medicine in combination with the established technique of antenatal ultrasound. A review of the literature to date provides information for clinicians to help assess which patient...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0b013e32832947ab
更新日期：2009-04-01 00:00:00
abstract：PURPOSE OF REVIEW:The prevention of breast, ovarian and endometrial cancer frequently involves hormonal or surgical interventions. Each of these may have noncancerous sequelae and can affect quality of life in women with hereditary cancer syndromes. The purpose of this review is to discuss the medical management of hor...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000146
更新日期：2015-02-01 00:00:00
abstract：:In contrast to the reduction in perinatal mortality in high-risk pregnancies, screening of low-risk pregnancies with umbilical artery Doppler ultrasonography has shown no benefit. Advances in pathophysiology question the assumption that the placenta is hypoxic in fetal growth restriction, with absent end-diastolic fre...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：PURPOSE OF REVIEW:This article reviews the potential benefits and downsides of early anatomy screening. RECENT FINDINGS:There is increasing evidence that about 50% of severe fetal anomalies can be diagnosed prior to 14 weeks of gestation. 'Red flags' such as an increased nuchal or intracranial translucency, tricuspid ...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0000000000000161
更新日期：2015-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Confidential enquiries of maternal deaths in the UK for 1997-1999 revealed that the number of indirect deaths from medical conditions exacerbated by pregnancy was greater than deaths from conditions directly caused by pregnancy. Indirect maternal deaths accounted for 36% of all deaths. Although neopla...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/00001703-200304000-00003
更新日期：2003-04-01 00:00:00
abstract：PURPOSE OF REVIEW:To review recent literature on medical accuracy, program effectiveness, and ethical concerns related to abstinence-only policies for adolescent sexuality education. RECENT FINDINGS:The federal government invests over 175 million dollars annually in 'abstinence-only-until-marriage' programs. These pro...
journal_title：Current opinion in obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1097/GCO.0b013e3282efdc0b
更新日期：2007-10-01 00:00:00
