Human heart valve-derived scaffold improves cardiac repair in a murine model of myocardial infarction.

abstract：:The treatment of testicular cancer includes unilateral orchiectomy and chemotherapy and is curative for most patients. However, observational studies revealed an association with depression, anxiety and cognitive impairment. It is unclear whether these side effects are caused by chemotherapy, hemicastration or the dis...

journal_title：Scientific reports

authors： Borbélyová V,Renczés E,Chovanec M,Mego M,Celec P

更新日期：2020-06-23 00:00:00

abstract：:The mammalian central nervous system (CNS) contains various types of neurons with different neuronal functions. In contrast to established roles of cell type-specific transcription factors on neuronal specification and maintenance, whether ubiquitous transcription factors have conserved or differential neuronal functi...

journal_title：Scientific reports

authors： Yamanaka T,Tosaki A,Miyazaki H,Kurosawa M,Koike M,Uchiyama Y,Maity SN,Misawa H,Takahashi R,Shimogori T,Hattori N,Nukina N

更新日期：2016-09-30 00:00:00

abstract：:Liver stage Plasmodium parasites reside in a parasitophorous vacuole (PV) that associates with lysosomes. It has previously been shown that these organelles can have beneficial as well as harmful effects on the parasite. Yet it is not clear how the association of lysosomes with the parasite is controlled and how inter...

journal_title：Scientific reports

authors： Niklaus L,Agop-Nersesian C,Schmuckli-Maurer J,Wacker R,Grünig V,Heussler VT

更新日期：2019-05-28 00:00:00

abstract：:Sharp increase in macromolecular crowding induces abnormal chromatin compaction in the cell nucleus, suggesting its non-negligible impact on chromatin structure and function. However, the details of the crowding-induced chromatin compaction remain poorly understood. In this work, we present a computer simulation study...

journal_title：Scientific reports

authors： Oh I,Choi S,Jung Y,Kim JS

更新日期：2018-04-03 00:00:00

abstract：:Natural Bacillus isolates generate limited amounts of surfactin (<10% of their biomass), which functions as an antibiotic or signalling molecule in inter-/intra-specific interactions. However, overproduction of surfactin in Bacillus amyloliquefaciens MT45 was observed at a titre of 2.93 g/l, which is equivalent to hal...

journal_title：Scientific reports

authors： Zhi Y,Wu Q,Xu Y

更新日期：2017-01-23 00:00:00

abstract：:The midline thalamus is reciprocally connected with the medial temporal lobe, where neural circuitry essential for spatial navigation and memory formation resides. Yet, little information is available on the dynamic relationship between activity patterns in the midline thalamus and medial temporal lobe. Here, we repor...

journal_title：Scientific reports

authors： Lara-Vásquez A,Espinosa N,Durán E,Stockle M,Fuentealba P

更新日期：2016-07-14 00:00:00

abstract：:The role of intraspecific variation in the magnitude and direction of plastic responses in ecology and evolution is increasingly recognized. However, the factors underlying intraspecific variation in plastic responses remain largely unexplored, particularly for the hypothesis that the herbivores' phenotypic response t...

journal_title：Scientific reports

authors： Sentis A,Bertram R,Dardenne N,Ramon-Portugal F,Louit I,Le Trionnaire G,Simon JC,Magro A,Pujol B,Hemptinne JL,Danchin E

更新日期：2019-06-21 00:00:00

abstract：:Passive immunotherapy may have particular benefits for the treatment of severe influenza infection in at-risk populations, however little is known of the impact of passive immunotherapy on the formation of memory responses to the virus. Ideally, passive immunotherapy should attenuate the severity of infection while st...

journal_title：Scientific reports

authors： Stevens NE,Hatjopolous A,Fraser CK,Alsharifi M,Diener KR,Hayball JD

更新日期：2016-07-06 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL, lipocalin 2 or LCN2) is an iron carrier protein whose circulating level is increased by kidney injury, bacterial infection and obesity, but its metabolic consequence remains elusive. To study physiological role of LCN2 in energy homeostasis, we challenged female Lcn2 k...

journal_title：Scientific reports

authors： Ishii A,Katsuura G,Imamaki H,Kimura H,Mori KP,Kuwabara T,Kasahara M,Yokoi H,Ohinata K,Kawanishi T,Tsuchida J,Nakamoto Y,Nakao K,Yanagita M,Mukoyama M,Mori K

更新日期：2017-11-14 00:00:00

abstract：:In this paper, a novel explanation on high directive emission of Fabry-Perot resonator antenna with subwavelength metasurface is proposed. Based on image theory and effective constitutive parameter retrieval, the whole Fabry-Perot resonant cavity structure composed of a single-layer metasurface with square ring elemen...

journal_title：Scientific reports

authors： Liu ZG,Lu WB,Yang W

更新日期：2017-09-13 00:00:00

abstract：:We studied the spin-transfer torque (STT) in graphene based normal-metal/topological-insulator/ferromagnet heterostructures (N/TI/F), which is induced by the helical spin-polarized current in the quantum spin Hall insulator. We found that the STT is comparable in magnitude to the STT in ferromagnetic-normal- ferromagn...

journal_title：Scientific reports

authors： Zhang Q,Chan KS,Li J

更新日期：2018-03-12 00:00:00

abstract：:Combining the advantages of structured random measurement matrix and chaotic structure, this paper introduces a color image encryption algorithm based on a structural chaotic measurement matrix and random phase mask. The Chebyshev chaotic sequence is used in the algorithm to generate the flip permutation matrix, the s...

journal_title：Scientific reports

authors： Wang X,Su Y

更新日期：2020-10-29 00:00:00

abstract：:We evaluated bioactive glass graft (S53P4) in patients undergoing Le Fort I osteotomy, with non-grafted patients as controls. Computed tomography facial scans of the 25 patients submitted for Le Fort I were divided into two groups: Group 1-S53P4 group and Group 2-without grafting. CT scans were analyzed in the immedia...

journal_title：Scientific reports

authors： de Souza Cruz EL,de Souza FJ Jr,de Menezes LM,Tuji FM,Carneiro JT Jr

更新日期：2020-07-29 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common cause of malignancy-related mortality worldwide. It is urgently needed to develop potential drugs with good efficacy and low toxicity for HCC treatment. The anti-tumor effect of Traditional Chinese Medicine (TCM) has received increasing attention worldwide. Tram...

journal_title：Scientific reports

authors： Hu Z,Yang A,Su G,Zhao Y,Wang Y,Chai X,Tu P

更新日期：2016-08-09 00:00:00

abstract：:Factor induced reprogramming of fibroblasts is an orchestrated but inefficient process. At the epigenetic level, it results in drastic chromatin changes to erase the existing somatic "memory" and to establish the pluripotent state. Accordingly, alterations of chromatin regulators including Ezh2 influence iPSC generati...

journal_title：Scientific reports

authors： Rao RA,Dhele N,Cheemadan S,Ketkar A,Jayandharan GR,Palakodeti D,Rampalli S

更新日期：2015-02-04 00:00:00

abstract：:Staphylococcus aureus can cause different types of diseases from mild skin infections to life-threatening sepsis worldwide. Owing to the emergence and transmission of multidrug-resistant strains, developing an impactful immunotherapy especially vaccine control approach against S. aureus infections is increasingly enco...

journal_title：Scientific reports

authors： Yu W,Yao D,Yu S,Wang X,Li X,Wang M,Liu S,Feng Z,Chen X,Li W,Wang L,Liu W,Ma J,Yu L,Tong C,Song B,Cui Y

更新日期：2018-02-26 00:00:00

abstract：:We show that H-bonded host-guest systems associate in ionic liquids (ILs), pure salts with melting point below room temperature, in which dipole-dipole electrostatic interactions should be negligible in comparison with dipole-charge interactions. Binding constants (Ka) obtained from titrations of four H-bonded host-gu...

journal_title：Scientific reports

authors： Naranjo T,Álvarez-Asencio R,Pedraz P,Nieto-Ortega B,Silva SM,Burzurí E,Rutland MW,Pérez EM

更新日期：2020-09-22 00:00:00

abstract：:Early ontogenetic periods and postnatal maturation in organisms are sex-specifically sensitive to hypothalamic-pituitary-adrenal (HPA)-axis activities, related glucocorticoid secretions, and their effects on energy balance and homeostasis. Dietary polyunsaturated (PUFAs) and saturated (SFAs) fatty acids potentially pl...

journal_title：Scientific reports

authors： Nemeth M,Millesi E,Schuster D,Quint R,Wagner KH,Wallner B

更新日期：2018-01-11 00:00:00

abstract：:Sludge bulking is a major problem that restricts the development of the activated sludge process. The microbial community responsible for sludge bulking varies depending on water quality and operational conditions. This study analysed the microbial community of bulking sludge in oxidation ditch with ultra-low sludge l...

journal_title：Scientific reports

authors： Zhang M,Yao J,Wang X,Hong Y,Chen Y

更新日期：2019-09-23 00:00:00

abstract：:VCF2CNA is a tool (Linux commandline or web-interface) for copy-number alteration (CNA) analysis and tumor purity estimation of paired tumor-normal VCF variant file formats. It operates on whole genome and whole exome datasets. To benchmark its performance, we applied it to 46 adult glioblastoma and 146 pediatric neur...

journal_title：Scientific reports

authors： Putnam DK,Ma X,Rice SV,Liu Y,Newman S,Zhang J,Chen X

更新日期：2019-07-17 00:00:00

abstract：:Individuals in the state of psychological suboptimal health keep increasing, only scales and questionnaires were used to diagnose in clinic under current conditions, and symptoms of high reliability and accuracy are destitute. Therefore, the noninvasive and precise laboratory diagnostic methods are needed. This study ...

journal_title：Scientific reports

authors： Tian JS,Xia XT,Wu YF,Zhao L,Xiang H,Du GH,Zhang X,Qin XM

更新日期：2016-09-21 00:00:00

abstract：:In earlier studies, we showed that ATF4 down-regulation affects post-synaptic development and dendritic spine morphology in neurons through increased turnover of the Rho GTPase Cell Division Cycle 42 (Cdc42) protein. Here, we find that ATF4 down-regulation in both hippocampal and cortical neuron cultures reduces prote...

journal_title：Scientific reports

authors： Pasini S,Liu J,Corona C,Peze-Heidsieck E,Shelanski M,Greene LA

更新日期：2016-11-14 00:00:00

abstract：:Urban water supplies are critical to the growth of the city and the wellbeing of its citizens. However, these supplies can be vulnerable to hydrological extremes, such as droughts and floods, especially if they are the main source of water for the city. Maintaining these supplies and preparing for future conditions is...

journal_title：Scientific reports

authors： Obringer R,Nateghi R

更新日期：2018-03-26 00:00:00

abstract：:Ultraviolet radiation (UVR) is a major environmental genotoxic agent. In skin, it can lead to the formation of mutagenic DNA damage. Several mechanisms are in place to prevent the conversion of these DNA damage into skin cancer-driver mutations. An important mutation prevention mechanism is the programmed cell death, ...

journal_title：Scientific reports

authors： Gary AS,Rochette PJ

更新日期：2020-11-03 00:00:00

abstract：:Reef sharks are vulnerable predators experiencing severe population declines mainly due to overexploitation. However, beyond direct exploitation, human activities can produce indirect or sub-lethal effects such as behavioral alterations. Such alterations are well known for terrestrial fauna but poorly documented for m...

journal_title：Scientific reports

authors： Juhel JB,Vigliola L,Wantiez L,Letessier TB,Meeuwig JJ,Mouillot D

更新日期：2019-02-27 00:00:00

abstract：:Polygenic risk scores (PRS) from genome-wide association studies (GWAS) are increasingly used to predict disease risks. However some included variants could be false positives and the raw estimates of effect sizes from them may be subject to selection bias. In addition, the standard PRS approach requires testing over ...

journal_title：Scientific reports

authors： So HC,Sham PC

更新日期：2017-02-01 00:00:00

abstract：:Methicillin resistant Staphylococcus aureus (MRSA) is a major human pathogen, which causes superficial to lethal clinical infections. Neutrophils are the most abundant leukocytes in the blood and are the first defense mechanism against S. aureus infections. Here we show Staphylococcal Superantigen-Like protein 11 (SSL...

journal_title：Scientific reports

authors： Chen C,Yang C,Barbieri JT

更新日期：2019-03-12 00:00:00

abstract：:Fear of predation can induce profound changes in the behaviour and physiology of prey species even if predator encounters are infrequent. For echolocating toothed whales, the use of sound to forage exposes them to detection by eavesdropping predators, but while some species exploit social defences or produce cryptic a...

journal_title：Scientific reports

authors： Aguilar de Soto N,Visser F,Tyack PL,Alcazar J,Ruxton G,Arranz P,Madsen PT,Johnson M

更新日期：2020-02-06 00:00:00

abstract：:Adult zebrafish have the ability to regenerate cells of the central nervous system. However, few neuronal regeneration studies in adult zebrafish addressed their ability to regenerate specific types of neurons following cell specific ablation. We show here that treatment of transgenic Tg(dat:CFP-NTR) adult zebrafish w...

journal_title：Scientific reports

authors： Godoy R,Hua K,Kalyn M,Cusson VM,Anisman H,Ekker M

更新日期：2020-07-30 00:00:00

abstract：:The bacterial stringent response is a key regulator of bacterial virulence, biofilm formation and antibiotic tolerance, and is a promising target for the development of new antibacterial compounds. The intracellular nucleotide (p)ppGpp acts as a messenger orchestrating the stringent response. A synthetic peptide 1018 ...

journal_title：Scientific reports

authors： Andresen L,Tenson T,Hauryliuk V

更新日期：2016-11-07 00:00:00