当前位置： SCI文献检索 > GENERAL AND COMPARATIVE ENDOCRINOLOGY期刊下所有文献 > Impairment of microvascular angiogenesis is associated with delay in prostatic development in rat offspring of maternal protein malnutrition.

Impairment of microvascular angiogenesis is associated with delay in prostatic development in rat offspring of maternal protein malnutrition.

Abstract：

:Experimental data demonstrated the negative impact of maternal protein malnutrition (MPM) on rat prostate development, but the mechanism behind the impairment of prostate growth has not been well understood. Male Sprague Dawley rats, borned to dams fed a normal protein diet (CTR group, 17% protein diet), were compared with those borned from dams fed a low protein diet (6% protein diet) during gestation (GLP group) or gestation and lactation (GLLP). The ventral prostate lobes (VP) were removed at post-natal day (PND) 10 and 21, and analyzed via different methods. The main findings were low birth weight, a reduction in ano-genital distance (AGD, a testosterone-dependent parameter), and an impairment of prostate development. A delay in prostate morphogenesis was associated with a reduced testosterone levels and angiogenic process through downregulation of aquaporin-1 (AQP-1), insulin/IGF-1 axis and VEGF signaling pathway. Depletion of the microvascular network, which occurs in parallel to the impairment of proliferation and differentiation of the epithelial cells, affects the bidirectional flux between blood vessels impacting prostatic development. In conclusion, our data support the hypothesis that a reduction in microvascular angiogenesis, especially in the subepithelial compartment, is associated to the impairment of prostate morphogenesis in the offspring of MPM dams.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Colombelli KT,Santos SAA,Camargo ACL,Constantino FB,Barquilha CN,Rinaldi JC,Felisbino SL,Justulin LA

doi

10.1016/j.ygcen.2016.12.016

subject

Has Abstract

pub_date

2017-05-15 00:00:00

pages

258-269

eissn

0016-6480

issn

1095-6840

pii

S0016-6480(16)30494-4

journal_volume

246

pub_type

杂志文章

相关文献

GENERAL AND COMPARATIVE ENDOCRINOLOGY文献大全
  • Changes in plasma cortisol during stress and smoltification in coho salmon, Oncorhynchus kisutch.

    abstract：:The cortisol stress response in juvenile coho salmon, Oncorhynchus kisutch, considered as the difference between resting and peak poststress cortisol levels, increased from 80 ng/ml in March to 166 ng/ml in July, the period when smoltification normally occurs. Resting plasma cortisol levels also continually increased ...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(85)90406-x

    authors： Barton BA,Schreck CB,Ewing RD,Hemmingsen AR,Patiño R

    更新日期：1985-09-01 00:00:00

  • Vitellogenin of Fujian oyster, Crassostrea angulata: Synthesized in the ovary and controlled by estradiol-17β.

    abstract：:In this study, we cloned a full-length cDNA encoding vitellogenin (Vg) in the Fujian oyster Crassostrea angulata. The complete Vg cDNA consists of 5160 nucleotides with a long open reading frame encoding 1641 amino acid residues. The deduced amino acid sequence shared high similarity with the Vgs of other mollusc, fis...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2014.03.034

    authors： Ni J,Zeng Z,Kong D,Hou L,Huang H,Ke C

    更新日期：2014-06-01 00:00:00

  • The effects of age, season, and gender on serum cortisol levels in the tammar wallaby, Macropus eugenii.

    abstract：:Serum cortisol levels were measured in a total of 73 tammar wallabies maintained in a captive population at Macquarie University, NSW, Australia. Previous studies of corticosteroids in marsupials have generally involved low sample numbers, a diverse array of analytical techniques, and a variety of sampling conditions....

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0016-6480(03)00185-0

    authors： McKenzie S,Deane EM

    更新日期：2003-10-01 00:00:00

  • The number of life-history stages does not influence the androgen responsiveness to male-male interactions: sedentary and migratory black redstarts (Phoenicurus ochruros) do not elevate testosterone in response to simulated territorial intrusions.

    abstract：:High plasma levels of testosterone at the beginning of the breeding season adjust male physiology for mating and promote territorial behavior in birds. Conversely intra-sexual competition may elicit a temporary increase in circulating testosterone. Male black redstarts (Phoenicurus ochruros) from migratory populations...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2014.04.017

    authors： Villavicencio CP,Blas J,Goymann W

    更新日期：2014-09-01 00:00:00

  • Transcriptional signature of progesterone in the fathead minnow ovary (Pimephales promelas).

    abstract：:A growing number of studies have examined transcriptional responses to sex steroids along the hypothalamic-pituitary-gonadal axis in teleost fishes. However, data are lacking on the molecular cascades that underlie progesterone signaling. The objective of this study was to characterize the transcriptional response in ...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2013.06.008

    authors： Garcia-Reyero N,Martyniuk CJ,Kroll KJ,Escalon BL,Spade DJ,Denslow ND

    更新日期：2013-10-01 00:00:00

  • Molecular cloning, tissue distribution, and developmental expression of lamprey transthyretins.

    abstract：:We isolated and cloned full-length cDNAs of transthyretin (TTR) from 2 genera of lamprey, Petromyzon marinus and Lampetra appendix. These sequences represent the first report of TTR sequences in vertebrates basal to teleost fishes. The deduced amino acid sequence of lamprey TTR cDNAs showed 36-47% identity with those ...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2006.11.017

    authors： Manzon RG,Neuls TM,Manzon LA

    更新日期：2007-03-01 00:00:00

  • Testosterone influences song behaviour and social dominance - but independent of prenatal yolk testosterone exposure.

    abstract：:In the last two decades, maternally derived yolk androgens have been shown to significantly alter offspring development, and a number of these effects persist into adulthood. However, little is known about their underlying mechanisms. Mechanisms that have been suggested are changes in the endogenous androgen productio...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2013.10.014

    authors： Vergauwen J,Groothuis TG,Eens M,Müller W

    更新日期：2014-01-01 00:00:00

  • Cardiovascular and vasoconstrictive actions of skate bradykinin in the little skate, Leucoraja erinacea (Elasmobranchii).

    abstract：:The vasoconstrictive and cardiovascular actions of a recently identified bradykinin (BK)-related peptide (Gly-Ile-Thr-Ser-Trp-Leu-Pro-Phe) from the little skate, Leucoraja erinacea were examined in the unanesthetised little skate. Intra-arterial administration of a skate BK (0.1-1 nmolkg(-1)) produced a hypertensive r...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2011.08.002

    authors： Dasiewicz PJ,Conlon JM,Anderson WG

    更新日期：2011-11-01 00:00:00

  • Brain-pituitary-gonadal axis during early development and sexual differentiation in the rainbow trout, Oncorhynchus mykiss.

    abstract：:Profiles of testosterone, 11-ketotestosterone, androstenedione, and estradiol were determined by RIA, and immunocytochemical techniques were employed to identify gonadotropin (GTH) I and II and gonadotropin releasing hormone (GnRH) in monosex and mixed sex populations of rainbow trout from 1 to 126 days postfertilizat...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.1996.0083

    authors： Feist G,Schreck CB

    更新日期：1996-06-01 00:00:00

  • The effect of cortisol on the secretion of sex steroids from cultured ovarian follicles of rainbow trout.

    abstract：:In a series of experiments, the effect of cortisol on the ability of rainbow trout (Salmo gairdneri) ovarian follicles to secrete sex steroids in vitro was investigated. The basal rate of secretion of sex steroids (oestradiol and testosterone) was suppressed in a dose-dependent manner by the addition of cortisol to th...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(90)90230-j

    authors： Carragher JF,Sumpter JP

    更新日期：1990-03-01 00:00:00

  • Prenatal development of hematopoietic and hormone-producing cells in the chicken adenohypophysis.

    abstract：:The developmental sequence of markers for hematopoietic, hormone-producing, and folliculo-stellate cells in the chicken adenohypophysis is described using immunohistochemical staining techniques. Hematopoietic cells are detected in cryosections of the adenohypophysis starting from 10- or 12-day embryos, using chicken-...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.1998.7235

    authors： Allaerts W,Boonstra-Blom AG,Peeters K,Janse EM,Berghman LR,Jeurissen SH

    更新日期：1999-05-01 00:00:00

  • A possible involvement of prostaglandin F2 alpha (PGF2 alpha) in Rana esculenta ovulation: effects of mammalian gonadotropin-releasing hormone on in vitro PGF2 alpha and 17 beta-estradiol production from ovary and oviduct.

    abstract：:The present work studied the PGF2 alpha and 17 beta-estradiol plasma levels during ovulation, and the in vitro effects of mammalian gonadotropin-releasing hormone (mGnRH) on ovarian and oviductal production of prostaglandin F2 alpha (PGF2 alpha) and 17 beta-estradiol during four different stages of the annual sexual c...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(92)90018-f

    authors： Gobbetti A,Zerani M

    更新日期：1992-08-01 00:00:00

  • A nonsteroidal follicular factor is involved in maturation process of Xenopus laevis oocytes.

    abstract：:Xenopus laevis postvitellogenic ovarian follicles release into conditioned medium nonsteroidal factor(s) that potentiate progesterone-induced oocyte maturation. The molecular weight of this factor is between 1000 and 10,000 Da. The potentiating activity is suppressed when follicles are incubated with cyanoketone to in...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(92)90115-z

    authors： Chesnel F,Bourry A,Boujard D,Joly J

    更新日期：1992-05-01 00:00:00

  • Molecular evolution of adiponectin in Carnivora and its mRNA expression in relation to hepatic lipidosis.

    abstract：:Adiponectin is a novel adipocyte-derived hormone with low circulating concentrations and/or mRNA expression in obesity and non-alcoholic fatty liver disease (NAFLD). The adiponectin mRNA of several Carnivora species was sequenced to enable further gene expression studies in this clade with potential experimental speci...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2010.05.010

    authors： Nieminen P,Rouvinen-Watt K,Kapiainen S,Harris L,Mustonen AM

    更新日期：2010-09-15 00:00:00

  • Immunocytochemical and histological differences in the interrenal axis of feral brown trout, Salmo trutta, in metal-contaminated waters.

    abstract：:There are more CRH-like immunoreactive neurons in the preoptic nucleus and nucleus lateralis tuberis in the brain of feral brown trout, Salmo trutta, living in cadmium- and zinc-contaminated regions of the Eagle River than in fish from an uncontaminated control site. Histological analyses revealed that interrenal cell...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.1997.7000

    authors： Norris DO,Felt SB,Woodling JD,Dores RM

    更新日期：1997-12-01 00:00:00

  • The effects of acute and chronic stress on the levels of reproductive hormones in the plasma of mature male brown trout, Salmo trutta L.

    abstract：:Chronic confinement for 1 month caused a significant elevation of plasma cortisol but suppressed the levels of plasma testosterone and 11-ketotestosterone in sexually mature male brown trout. An acute handling stress for 1 hr elevated blood cortisol and ACTH levels and also suppressed circulating androgens. This andro...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/0016-6480(87)90036-0

    authors： Pickering AD,Pottinger TG,Carragher J,Sumpter JP

    更新日期：1987-11-01 00:00:00

  • Glucose stimulates the release of bombyxin, an insulin-related peptide of the silkworm Bombyx mori.

    abstract：:The effects of starvation and feeding on the release of bombyxin, a peptide of insulin superfamily in insects, from the larval brain of the silkworm Bombyx mori were investigated. Following starvation, the bombyxin titer in the hemolymph of larvae decreased, whereas its content in the brain increased. On the other han...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.1999.7438

    authors： Masumura M,Satake S,Saegusa H,Mizoguchi A

    更新日期：2000-06-01 00:00:00

  • Ultrastructural comparison of the perisympathetic organs in three Coleoptera: Chrysocarabus auronitens F., Oryctes rhinoceros L. and Tenebrio molitor L.

    abstract：:Ultrastructural comparison of different types of perisympathetic organs (POs) in three species of Coleoptera (Chrysocarabus auronitens, Oryctes rhinoceros, and Tenebrio molitor) showed that the structure of these organs was not related to their morphological types but to their topography. Two kinds of PO structure may...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(83)90203-4

    authors： Provansal-Baudez A,Baudry-Partiaoglou N

    更新日期：1983-03-01 00:00:00

  • Partial food restriction increases hepatic inner ring deiodinating activity in the chicken and the rat.

    abstract：:The effects of a long term partial food restriction were studied in chickens and rats. In chickens the treatment resulted in increased plasma T4 levels while T4 levels in rats remained unchanged. Plasma T3 decreased in both species. In vitro hepatic outer ring deiodinating type I (ORD-I) activity was not influenced by...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.1995.1164

    authors： Darras VM,Cokelaere M,Dewil E,Arnouts S,Decuypere E,Kühn ER

    更新日期：1995-12-01 00:00:00

  • Degradation of gonadotropin-releasing hormones in the gilthead seabream, Sparus aurata. I. Cleavage of native salmon GnRH and mammalian LHRH in the pituitary.

    abstract：:The pattern and kinetics of degradation of native salmon gonadotropin-releasing hormone (sGnRH) and mammalian leuteinizing hormone-releasing hormone (LHRH) by pituitary bound enzymes were studied in the gilthead seabream, Sparus aurata. sGnRH and LHRH were incubated for different periods of time with membrane or cytos...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(90)90115-3

    authors： Goren A,Zohar Y,Fridkin M,Elhanati E,Koch Y

    更新日期：1990-08-01 00:00:00

  • Food intake, growth, and expression of neuropeptides regulating appetite in clown anemonefish (Amphiprion ocellaris) exposed to predicted climate changes.

    abstract：:The clown anemonefish (Amphiprion ocellaris) is a common model species in studies assessing the impact of climate changes on tropical coral fish physiology, metabolism, growth, and stress. However, the basic endocrine principles for the control of food intake and energy homeostasis, under normal and elevated sea tempe...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2021.113719

    authors： Pham LP,Olderbakk Jordal AE,Nguyen MV,Rønnestad I

    更新日期：2021-01-18 00:00:00

  • Biosynthesis and axonal transport of multiple molluscan insulin-related peptides by the neuroendocrine light green cells of Lymnaea stagnalis.

    abstract：:The neuroendocrine light green cells (LGCs) control body growth and metabolism of the freshwater snail, Lymnaea stagnalis. These cells, located in the cerebral ganglia, use the peripheries of the median lip nerves (MLNs) as the neurohemal area. The LGCs express four members of a gene family encoding the precursors of ...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(92)90152-a

    authors： Li KW,Geraerts WP,van Loenhout H,Joosse J

    更新日期：1992-07-01 00:00:00

  • Isolation and structural characterization of proglucagon-derived peptides, pancreatic polypeptide, and somatostatin from the urodele Amphiuma tridactylum.

    abstract：:The expression of the preproglucagon gene in vertebrates is markedly species- and tissue-dependent. Three peptides derived from the posttranslational processing of preproglucagon were isolated from an extract of the pancreas of the urodele Amphiuma tridactylum (threetoed amphiuma). The primary structures of the peptid...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.1996.0003

    authors： Cavanaugh ES,Nielsen PF,Conlon JM

    更新日期：1996-01-01 00:00:00

  • Maternal androgen levels during pregnancy are associated with early-life growth in Geoffroy's marmosets, Callithrix geoffroyi.

    abstract：:Fetal development is a critical period of physical development, and factors in the intrauterine environment can cause lasting effects on the growth and development of offspring. There is little research evaluating organizational effects of early androgen exposure of endogenous maternal origins on the prenatal and post...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.ygcen.2009.10.008

    authors： Smith AS,Birnie AK,French JA

    更新日期：2010-04-01 00:00:00

  • Effects of time, photoperiod, and pinealectomy on ocular and plasma melatonin concentrations in the chick.

    abstract：:Pinealectomized and intact chicks raised under cyclic (14L:10D) and noncyclic (OL;24L) conditions of environmental lighting were sampled 60 hr and 6 weeks after pinealectomy to evaluate the effects of pineal ablation on plasma and ocular melatonin concentrations. Little or no immunoreactive melatonin was present in pl...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(85)90114-5

    authors： Osol G,Schwartz B,Foss DC

    更新日期：1985-06-01 00:00:00

  • Localization of a salmon calcitonin-like molecule in one type of ultimobranchial cells in the freshwater turtle Pseudemys scripta.

    abstract：:Immunohistochemical methods using affinity adsorbed antibodies raised against the three families of calcitonins (CT) were applied to ultimobranchial (UB) cells in situ to investigate the nature of the Chelonian calcitonin molecule and its distribution in the ultimobranchial bodies of the freshwater turtle, Pseudemys s...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(87)90127-4

    authors： Boudbid H,Leger AF,Pidoux E,Volle GE,Taboulet J,Moukhtar MS,Treilhou-Lahille F

    更新日期：1987-03-01 00:00:00

  • Regulation of hepatic growth hormone receptors in coho salmon (Oncorhynchus kisutch).

    abstract：:Factors potentially regulating hepatic growth hormone (GH) receptors in coho salmon (Oncorhynchus kisutch) have been investigated. From December to June of the first year, relative changes in hepatic 125I-sGH binding and 35SO4 incorporation by ceratobranchial cartilage were similar. Stunted salmon, which in seawater h...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(92)90256-j

    authors： Gray ES,Kelley KM,Law S,Tsai R,Young G,Bern HA

    更新日期：1992-11-01 00:00:00

  • Novel discoveries in acid-base regulation and osmoregulation: A review of selected hormonal actions in zebrafish and medaka.

    abstract：:Maintenance of internal ionic and acid-base homeostasis is critical for survival in all biological systems. Similar to mammals, aquatic fishes have developed sophisticated homeostatic mechanisms to mitigate metabolic or environmental disruptions in ionic and acid-base status of systemic body fluids via hormone-control...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygcen.2019.03.007

    authors： Yan JJ,Hwang PP

    更新日期：2019-06-01 00:00:00

  • Gonadotropin-releasing hormone-immunoreactive neurons and associated nicotinamide adenine dinucleotide phosphate-diaphorase-positive neurons in the brain of a teleost, Rhodeus amarus.

    abstract：:Using combined nicotinamide adenine dinucleotide phosphate-diaphorase (NADPHd) histochemistry and salmon gonadotropin-releasing hormone (sGnRH) immunocytochemistry, it is reported for the first time that possible potential contacts occur between the nitric oxide (NO)- and the GnRH-containing neurons in the brain of a ...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1006/gcen.2000.7541

    authors： Baby SM,Ueck M,Prasada Rao PD

    更新日期：2000-10-01 00:00:00

  • Investigations of endocrine cells in the gastrointestinal tract and pancreas during the metamorphosis of an anuran (Alytes obstetricans L.): histochemical detection of APUD cells.

    abstract：:Endocrine cells were detected at premetamorphosis, prometamorphosis, climax, and juvenile stages using an amine-inducing fluorescence technique with or without previous L-3,4-dihydroxyphenylalanine (L-DOPA) treatment. At premetamorphosis, serotonin cells exhibited yellow fluorescence in the gut primary epithelium of t...

    journal_title：General and comparative endocrinology

    pub_type： 杂志文章

    doi：10.1016/0016-6480(88)90029-9

    authors： L'Hermite A,Hourdry J,Ferrand R

    更新日期：1988-03-01 00:00:00