Memory consolidation reconfigures neural pathways involved in the suppression of emotional memories.

abstract：:Cells couple growth with division and regulate size in response to nutrient availability. In rod-shaped fission yeast, cell-size control occurs at mitotic commitment. An important regulator is the DYRK-family kinase Pom1, which forms gradients from cell poles and inhibits the mitotic activator Cdr2, itself localized a...

journal_title：Nature communications

authors： Kelkar M,Martin SG

更新日期：2015-10-07 00:00:00

abstract：:Developmental plasticity describes the influence of environmental factors on phenotypic variation. An important mediator of developmental plasticity in many animals is parental care. Here, we examine the consequences of maternal care on offspring after the initial mass provisioning of brood in the small carpenter bee,...

journal_title：Nature communications

authors： Arsenault SV,Hunt BG,Rehan SM

更新日期：2018-08-27 00:00:00

abstract：:FDA proactively invests in tools to support innovation of emerging technologies, such as infectious disease next generation sequencing (ID-NGS). Here, we introduce FDA-ARGOS quality-controlled reference genomes as a public database for diagnostic purposes and demonstrate its utility on the example of two use cases. We...

journal_title：Nature communications

authors： Sichtig H,Minogue T,Yan Y,Stefan C,Hall A,Tallon L,Sadzewicz L,Nadendla S,Klimke W,Hatcher E,Shumway M,Aldea DL,Allen J,Koehler J,Slezak T,Lovell S,Schoepp R,Scherf U

更新日期：2019-07-25 00:00:00

abstract：:Extrachromosomal telomeric circles are commonly invoked as important players in telomere maintenance, but their origin has remained elusive. Using electron microscopy analysis on purified telomeres we show that, apart from known structures, telomeric repeats accumulate internal loops (i-loops) that occur in the proxim...

journal_title：Nature communications

authors： Mazzucco G,Huda A,Galli M,Piccini D,Giannattasio M,Pessina F,Doksani Y

更新日期：2020-10-20 00:00:00

abstract：:Analyzing scattered wave to recognize object is of fundamental significance in wave physics. Recently-emerged deep learning technique achieved great success in interpreting wave field such as in ultrasound non-destructive testing and disease diagnosis, but conventionally need time-consuming computer postprocessing or ...

journal_title：Nature communications

authors： Weng J,Ding Y,Hu C,Zhu XF,Liang B,Yang J,Cheng J

更新日期：2020-12-09 00:00:00

abstract：:Perception is guided by the anticipation of future events. It has been hypothesized that this process may be implemented by pattern completion in early visual cortex, in which a stimulus sequence is recreated after only a subset of the visual input is provided. Here we test this hypothesis using ultra-fast functional ...

journal_title：Nature communications

authors： Ekman M,Kok P,de Lange FP

更新日期：2017-05-23 00:00:00

abstract：:Wild boar (Sus scrofa) drastically colonized mainland Eurasia and North Africa, most likely from East Asia during the Plio-Pleistocene (2-1Mya). In recent studies, based on genome-wide information, it was hypothesized that wild boar did not replace the species it encountered, but instead exchanged genetic materials wi...

journal_title：Nature communications

authors： Liu L,Bosse M,Megens HJ,Frantz LAF,Lee YL,Irving-Pease EK,Narayan G,Groenen MAM,Madsen O

更新日期：2019-04-30 00:00:00

abstract：:Large-scale genomic data highlight the complexity and diversity of the molecular changes that drive cancer progression. Statistical analysis of cancer data from different tissues can guide drug repositioning as well as the design of targeted treatments. Here, we develop an improved Bayesian network model for tumour mu...

journal_title：Nature communications

authors： Kuipers J,Thurnherr T,Moffa G,Suter P,Behr J,Goosen R,Christofori G,Beerenwinkel N

更新日期：2018-10-19 00:00:00

abstract：:Recent years have witnessed the growing interest in the remote functionalization of alkenes for it offers a strategy to activate the challenging C-H bonds distant from the initiation point via alkene isomerization/functionalization. However, the catalytic enantioselective isomerization/functionalization with one singl...

journal_title：Nature communications

authors： Chen X,Cheng Z,Guo J,Lu Z

更新日期：2018-09-26 00:00:00

abstract：:Symbiotic associations occur in every habitat on earth, but we know very little about their evolutionary histories. Current models of trait evolution cannot adequately reconstruct the deep history of symbiotic innovation, because they assume homogenous evolutionary processes across millions of years. Here we use a rec...

journal_title：Nature communications

authors： Werner GD,Cornwell WK,Sprent JI,Kattge J,Kiers ET

更新日期：2014-06-10 00:00:00

abstract：:Fatty acids (FAs) are not only essential components of cellular energy storage and structure, but play crucial roles in signalling. Here we present a toolkit of photoswitchable FA analogues (FAAzos) that incorporate an azobenzene photoswitch along the FA chain. By modifying the FAAzos to resemble capsaicin, we prepare...

journal_title：Nature communications

authors： Frank JA,Moroni M,Moshourab R,Sumser M,Lewin GR,Trauner D

更新日期：2015-05-22 00:00:00

abstract：:The combined effects of anthropogenic and biological CO2 inputs may lead to more rapid acidification in coastal waters compared to the open ocean. It is less clear, however, how redox reactions would contribute to acidification. Here we report estuarine acidification dynamics based on oxygen, hydrogen sulfide (H2S), p...

journal_title：Nature communications

authors： Cai WJ,Huang WJ,Luther GW 3rd,Pierrot D,Li M,Testa J,Xue M,Joesoef A,Mann R,Brodeur J,Xu YY,Chen B,Hussain N,Waldbusser GG,Cornwell J,Kemp WM

更新日期：2017-08-28 00:00:00

abstract：:Rearrangement reactions have attracted considerable interest over the past decades due to their high bond-forming efficiency and atom economy in the construction of complex organic architectures. In contrast to the well-established [3,3]-rearrangement, [1,3] O-to-C rearrangement has been far less vigorously investigat...

journal_title：Nature communications

authors： Zhou B,Zhang YQ,Zhang K,Yang MY,Chen YB,Li Y,Peng Q,Zhu SF,Zhou QL,Ye LW

更新日期：2019-07-19 00:00:00

abstract：:Maize rough dwarf disease (MRDD), caused by various species of the genus Fijivirus, threatens maize production worldwide. We previously identified a quantitative locus qMrdd1 conferring recessive resistance to one causal species, rice black-streaked dwarf virus (RBSDV). Here, we show that Rab GDP dissociation inhibito...

journal_title：Nature communications

authors： Liu Q,Deng S,Liu B,Tao Y,Ai H,Liu J,Zhang Y,Zhao Y,Xu M

更新日期：2020-01-24 00:00:00

abstract：:Alike materials in the solid state, the phase diagram of type-II superconductors exhibit crystalline, amorphous, liquid and spatially inhomogeneous phases. The multitude of different phases of vortex matter has thence proven to act as almost ideal model system for the study of both the underlying properties of superco...

journal_title：Nature communications

authors： Reimann T,Mühlbauer S,Schulz M,Betz B,Kaestner A,Pipich V,Böni P,Grünzweig C

更新日期：2015-11-02 00:00:00

abstract：:Nuclear factor-κB (NFκB) and peroxisome proliferator activated receptor-γ (PPARγ) are both transcription factors that perform distinct but overlapping roles in cellular regulation. Here we report that PPARγ acts as an E3 ubiquitin ligase, physically interacting with p65 to induce its ubiquitination and degradation. Th...

journal_title：Nature communications

authors： Hou Y,Moreau F,Chadee K

更新日期：2012-01-01 00:00:00

abstract：:The importance of singlet oxygen (1O2) in the environmental and biomedical fields has motivated research for effective 1O2 production. Electrocatalytic processes hold great potential for highly-automated and scalable 1O2 synthesis, but they are energy- and chemical-intensive. Herein, we present a Janus electrocatalyti...

journal_title：Nature communications

authors： Zhao Y,Sun M,Wang X,Wang C,Lu D,Ma W,Kube SA,Ma J,Elimelech M

更新日期：2020-12-04 00:00:00

abstract：:Voltage-gated sodium channels (Na(v)) underlie the rapid upstroke of action potentials in excitable tissues. Binding of channel-interactive proteins is essential for controlling fast and long-term inactivation. In the structure of the complex of the carboxy-terminal portion of Na(v)1.5 (CTNa(v)1.5) with calmodulin (Ca...

journal_title：Nature communications

authors： Gabelli SB,Boto A,Kuhns VH,Bianchet MA,Farinelli F,Aripirala S,Yoder J,Jakoncic J,Tomaselli GF,Amzel LM

更新日期：2014-11-05 00:00:00

abstract：:Self-assembly of proteins and inorganic nanoparticles into terminal assemblies makes possible a large family of uniformly sized hybrid colloids. These particles can be compared in terms of utility, versatility and multifunctionality to other known types of terminal assemblies. They are simple to make and offer theoret...

journal_title：Nature communications

authors： Park JI,Nguyen TD,de Queirós Silveira G,Bahng JH,Srivastava S,Zhao G,Sun K,Zhang P,Glotzer SC,Kotov NA

更新日期：2014-05-20 00:00:00

abstract：:Alcohol oxidation reactions are widely used for the preparation of aldehydes and ketones. The electrolysis of alcohols to carbonyl compounds have been underutilized owing to low efficiency. Herein, we report an electrochemical oxidation of various alcohols in a continuous-flow reactor without external oxidants, base o...

journal_title：Nature communications

authors： Wang D,Wang P,Wang S,Chen YH,Zhang H,Lei A

更新日期：2019-06-26 00:00:00

abstract：:Non-line-of-sight (NLOS) imaging recovers objects using diffusely reflected indirect light using transient illumination devices in combination with a computational inverse method. While capture systems capable of collecting light from the entire NLOS relay surface can be much more light efficient than single pixel poi...

journal_title：Nature communications

authors： Liu X,Bauer S,Velten A

更新日期：2020-04-02 00:00:00

abstract：:Aerobic methane oxidation is catalyzed by particulate methane monooxygenase (pMMO), a copper-dependent, membrane metalloenzyme composed of subunits PmoA, PmoB, and PmoC. Characterization of the copper active site has been limited by challenges in spectroscopic analysis stemming from the presence of multiple copper bin...

journal_title：Nature communications

authors： Ro SY,Schachner LF,Koo CW,Purohit R,Remis JP,Kenney GE,Liauw BW,Thomas PM,Patrie SM,Kelleher NL,Rosenzweig AC

更新日期：2019-06-17 00:00:00

abstract：:SIRT1, the founding member of the mammalian family of seven NAD(+)-dependent sirtuins, is composed of 747 amino acids forming a catalytic domain and extended N- and C-terminal regions. We report the design and characterization of an engineered human SIRT1 construct (mini-hSIRT1) containing the minimal structural eleme...

journal_title：Nature communications

authors： Dai H,Case AW,Riera TV,Considine T,Lee JE,Hamuro Y,Zhao H,Jiang Y,Sweitzer SM,Pietrak B,Schwartz B,Blum CA,Disch JS,Caldwell R,Szczepankiewicz B,Oalmann C,Yee Ng P,White BH,Casaubon R,Narayan R,Koppetsch K,Bourb

更新日期：2015-07-02 00:00:00

abstract：:The mathematics of gauge theories lies behind many of the most profound advances in physics in the past 200 years, from Maxwell's theory of electromagnetism to Einstein's theory of general relativity. More recently it has become clear that gauge theories also emerge in condensed matter, a prime example being the spin-...

journal_title：Nature communications

authors： Benton O,Jaubert LD,Yan H,Shannon N

更新日期：2016-05-26 00:00:00

abstract：:The modern understanding of sleep is based on the classification of sleep into stages defined by their electroencephalography (EEG) signatures, but the underlying brain dynamics remain unclear. Here we aimed to move significantly beyond the current state-of-the-art description of sleep, and in particular to characteri...

journal_title：Nature communications

authors： Stevner ABA,Vidaurre D,Cabral J,Rapuano K,Nielsen SFV,Tagliazucchi E,Laufs H,Vuust P,Deco G,Woolrich MW,Van Someren E,Kringelbach ML

更新日期：2019-03-04 00:00:00

abstract：:The original version of this Article contained an error in Fig. 4. In the lower part of the three gene circuit diagrams in panel b, the flat-headed arrow linking lambdaCI to the tetR promoter incorrectly pointed to the tetR gene body. This has now been corrected in the HTML and PDF versions of this Article. ...

journal_title：Nature communications

authors： Purcell O,Wang J,Siuti P,Lu TK

更新日期：2019-01-08 00:00:00

abstract：:Circulating tumor cells (CTCs) have become an established biomarker for prognosis in patients with various carcinomas. However, current ex vivo CTC isolation technologies rely on small blood volumes from a single venipuncture limiting the number of captured CTCs. This produces statistical variability and inaccurate re...

journal_title：Nature communications

authors： Kim TH,Wang Y,Oliver CR,Thamm DH,Cooling L,Paoletti C,Smith KJ,Nagrath S,Hayes DF

更新日期：2019-04-01 00:00:00

abstract：:Protein aggregation plays a key role in neurodegenerative disease, giving rise to small oligomers that may become cytotoxic to cells. The fundamental microscopic reactions taking place during aggregation, and their rate constants, have been difficult to determine due to lack of suitable methods to identify and follow ...

journal_title：Nature communications

authors： Shammas SL,Garcia GA,Kumar S,Kjaergaard M,Horrocks MH,Shivji N,Mandelkow E,Knowles TP,Mandelkow E,Klenerman D

更新日期：2015-04-30 00:00:00

abstract：:Magmatic intrusions and volcanic eruptions are intimately related phenomena. Shallow magma intrusion builds subsurface reservoirs that are drained by volcanic eruptions. Thus, the long-held view is that intrusions must precede and feed eruptions. Here we show that explosive eruptions can also cause magma intrusion. We...

journal_title：Nature communications

authors： Castro JM,Cordonnier B,Schipper CI,Tuffen H,Baumann TS,Feisel Y

更新日期：2016-11-23 00:00:00

abstract：:Generation and recombination of electrons and holes in organic solar cells occurs via charge transfer states located at the donor/acceptor interface. The energy of these charge transfer states is a crucial factor for the attainable open-circuit voltage and its correct determination is thus of utmost importance for a d...

journal_title：Nature communications

authors： List M,Sarkar T,Perkhun P,Ackermann J,Luo C,Würfel U

更新日期：2018-09-07 00:00:00