Abstract：
:Here we provide, at least to our knowledge, the first evidence that aripiprazole (APPZ) in the water blunts the stress response of exposed fish in a concentration ten times lower than the concentration detected in the environment. Although the mechanism of APPZ in the neuroendocrine axis is not yet determined, our results highlight that the presence of APPZ residues in the environment may interfere with the stress responses in fish. Since an adequate stress response is crucial to restore fish homeostasis after stressors, fish with impaired stress response may have trouble to cope with natural and/or imposed stressors with consequences to their welfare and survival.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Barcellos HH,Kalichak F,da Rosa JG,Oliveira TA,Koakoski G,Idalencio R,de Abreu MS,Giacomini AC,Fagundes M,Variani C,Rossini M,Piato AL,Barcellos LJdoi
10.1038/srep37612subject
Has Abstractpub_date
2016-11-22 00:00:00pages
37612issn
2045-2322pii
srep37612journal_volume
6pub_type
杂志文章abstract：:To resolve the pore-associated bottleneck problem observed in the electrode materials used for ultracapacitors, which inhibits the transport of the electrolyte ions, we designed hierarchically structured activated carbon (HAC) by synthesizing a mesoporous silica template/carbon composite and chemically activating it t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21182
更新日期：2016-02-16 00:00:00
abstract：:Meaningful, reliable and valid mRNA expression analyses by real-time quantitative PCR (RT-qPCR) can only be achieved, if suitable reference genes are chosen for normalization and if appropriate RT-qPCR quality standards are met. Human periodontal ligament (hPDL) fibroblasts play a major mediating role in orthodontic t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15281-0
更新日期：2017-11-07 00:00:00
abstract：:Prolonged tomato consumption can mitigate ultraviolet (UV) light induced sunburn via unknown mechanisms. Dietary carotenoids distributed to skin are hypothesized to protect skin against UV-induced damage, although other phytochemicals may play a role. We hypothesize that tomato consumption would protect against skin c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05568-7
更新日期：2017-07-11 00:00:00
abstract：:Neonatal mice exhibit natural heart regeneration after myocardial infarction (MI) on postnatal day 1 (P1), but this ability is lost by postnatal day 7 (P7). Cardiac biomechanics intricately affect long-term heart function, but whether regenerated cardiac muscle is biomechanically similar to native myocardium remains u...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63324-w
更新日期：2020-04-30 00:00:00
abstract：:Coastal zones constitute one of the most heavily populated and developed land zones in the world. Despite the utility and economic benefits that coasts provide, there is no reliable global-scale assessment of historical shoreline change trends. Here, via the use of freely available optical satellite images captured si...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24630-6
更新日期：2018-04-27 00:00:00
abstract：:Fundamental understanding of guest gas replacement in hydrate reservoirs is crucial for the enhanced recovery of natural gas and carbon dioxide (CO2) sequestration. To gain physical insight into this exchange process, this work aims at developing and validating a clathrate hydrate model for gas replacement. Most of th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55476-1
更新日期：2019-12-11 00:00:00
abstract：:The blood-based diagnosis has a potential to provide an alternative approach for easy diagnosis of Alzheimer's disease (AD) with less invasiveness and low-cost. However, present blood-based AD diagnosis mainly focuses on measuring the plasma Aβ level because no other biomarkers are found to possess evident transport m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15703
更新日期：2015-10-27 00:00:00
abstract：:In a 250-kyr transient simulation of the Community Earth System Model (CESM), we identified a precessional forced seesaw of the summer middle-upper tropospheric eddy temperature between Asia and the North Pacific as the paleo-APO (Asian-Pacific oscillation). The paleo-APO variability is out of phase with the precessio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28349
更新日期：2016-07-06 00:00:00
abstract：:Light regulates cGMP concentration in the photoreceptor cytoplasm by activating phosphodiesterase (PDE) molecules through a G-protein signalling cascade. Spontaneous PDE activity is present in rod outer segments even in darkness. This basal PDE activity (βdark) has not been determined in wild type mammalian photorecep...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37661-w
更新日期：2019-02-04 00:00:00
abstract：:The use of lithium (Li) metal anodes has been reconsidered because of the necessity for a higher energy density in secondary batteries. However, Li metal anodes suffer from 'dead' Li formation and surface deactivation which consequently form a porous layer of redundant Li aggregates. In this work, a fibrous metal felt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30830
更新日期：2016-08-03 00:00:00
abstract：:Major overturn within a magma chamber can bring together felsic and mafic magmas, prompting de-volatilisation and acting as the driver for Plinian eruptions. Until now identification of mixing has been limited to analysis of lavas or individual crystals ejected during eruptions. We have recovered partially developed c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00731
更新日期：2012-01-01 00:00:00
abstract：:Antimicrobial peptides (AMPs) exhibit broad-spectrum antimicrobial activity, and have promise as new therapeutic agents. While the adult North American bullfrog (Rana [Lithobates] catesbeiana) is a prolific source of high-potency AMPs, the aquatic tadpole represents a relatively untapped source for new AMP discovery. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38442-1
更新日期：2019-02-06 00:00:00
abstract：:Hepcidin, a cysteine-rich peptide hormone, secreted mainly by the liver, plays a central role in iron metabolism regulation. Emerging evidence suggests that disordered iron metabolism is a risk factor for various types of diseases including cancers. However, it remains challenging to apply current mass spectrometry (M...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43756-9
更新日期：2019-05-13 00:00:00
abstract：:In this study, a novel resorufin thionocarbonate-based Hg2+-selective signaling probe (RT) for microfluidic paper-based analytical device (μPAD) applications is reported. The designed probe, RT, was readily synthesized by the one-step reaction of resorufin with phenyl thionochloroformate. The RT probe displayed a prom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40169-6
更新日期：2019-03-04 00:00:00
abstract：:Electroceutical wound dressings, especially those involving current flow with silver based electrodes, show promise for treating biofilm infections. However, their mechanism of action is poorly understood. We have developed an in vitro agar based model using a bioluminescent strain of Pseudomonas aeruginosa to measure...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37891-y
更新日期：2019-02-14 00:00:00
abstract：:Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified as the umami (savory) taste receptor. Amino acids and 5'-ribonucleotides are well known to be natural ligands for human...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30315-x
更新日期：2018-08-07 00:00:00
abstract：:Mammalian motor cortex consists of several interconnected subregions thought to play distinct roles in voluntary movements, yet their specific role in decision making and execution is not completely elucidated. Here we used transient optogenetic inactivation of the caudal forelimb area (CFA) and rostral forelimb area ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15835-2
更新日期：2017-11-17 00:00:00
abstract：:Immunopathology corresponds to self-damage of the inflammatory response, resulting from oxidizing molecules produced when the immune system is activated. Immunopathology often contributes to age-related diseases and is believed to accelerate ageing. Prevention of immunopathology relies on endogenous antioxidant enzyme...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12769-7
更新日期：2017-09-29 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60514-4
更新日期：2020-02-19 00:00:00
abstract：:Textile forms of solar cells possess special advantages over other types of solar cells, including their light weight, high flexibility, and mechanical robustness. Recent demand for wearable devices has promoted interest in the development of high-efficiency textile-based solar cells for energy suppliers. However, the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05322
更新日期：2014-06-24 00:00:00
abstract：:We report the thermal annealing-induced formation of ring-like structure of Zn(II)-doped magnetite from iron alkoxide leaf-like nanoplate precusor. The phase, structure and morphology of magnetite nanorings were comprehensively characterized by powder X-ray diffraction, X-ray photoelectron spectroscopy, atomic force m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45480
更新日期：2017-04-03 00:00:00
abstract：:Directional replacement and directional non-replacement models are two alternative paradigms for community development in primary successional environments. The first model emphasizes turnover in species between early and late successional niches. The second emphasizes accumulation of additional diversity over time. T...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26360
更新日期：2016-05-31 00:00:00
abstract：:Tracking animal behavior by video is one of the most common tasks in the life sciences. Although commercial software exists for executing this task, they often present enormous cost to the researcher and can entail purchasing hardware that is expensive and lacks adaptability. Additionally, the underlying code is often...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56408-9
更新日期：2019-12-27 00:00:00
abstract：:The pace of two-dimensional materials (2DM) research has been greatly accelerated by the ability to identify exfoliated thicknesses down to a monolayer from their optical contrast. Since this process requires time-consuming and error-prone manual assignment to avoid false-positives from image features with similar con...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23922-1
更新日期：2018-04-23 00:00:00
abstract：:New small molecules that regulate the step-wise differentiation of human pluripotent stem cells into dopaminergic neurons have been identified. The steroid, guggulsterone, was found to be the most effective inducer of neural stem cells into dopaminergic neurons. These neurons are extensively characterized and shown to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01463
更新日期：2013-01-01 00:00:00
abstract：:Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase domain containing 1 (NAPRT1) are the main human NAD salvage enzymes. NAD regulates energy metabolism and cell signaling, and the enzymes that control NAD availability are linked to pathologies such as cancer and neurodegeneration. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06311
更新日期：2014-09-09 00:00:00
abstract：:Silicon has emerged as the most promising high-capacity material for lithium-ion batteries. Waste glass can be a potential low cost and environmentally benign silica resource enabling production of nanosized silicon at the industry level. Windshields are generally made of laminated glass comprising two separate glass ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19529-1
更新日期：2018-01-17 00:00:00
abstract：:Mounting evidence indicated that human mesenchymal stem cells (hMSCs) are responsive not only to biochemical but also to physical cues, such as substrate topography and stiffness. To simulate the dynamic structures of extracellular environments of the marrow in vivo, we designed a novel surrogate substrate for marrow ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24264
更新日期：2016-04-15 00:00:00
abstract：:Increasing evidence suggests that pathological hallmarks of chronic degenerative syndromes progressively spread among interconnected brain areas in a disease-specific stereotyped pattern. Functional brain imaging from patients affected by various neurological syndromes such as traumatic brain injury and stroke indicat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29918-1
更新日期：2018-08-02 00:00:00
abstract：:The paper presents new knowledge on primary defect formation in tungsten (W) and iron (Fe) irradiated by fission and high-energy neutrons at near-room temperature. Using a well-established method of positron-annihilation lifetime-spectroscopy (PALS), it was found that irradiation of W in the fission reactor and by hig...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75737-8
更新日期：2020-11-03 00:00:00
