Abstract：
:G protein-coupled receptors (GPCRs) are a remarkably multifaceted family of transmembrane proteins that exert a variety of physiological effects. Although family A GPCRs are able to operate as monomers, there is increasing evidence that heteromerization represents a fundamental aspect of receptor function, trafficking and pharmacology. Most recently, it has been suggested that GPCR heteromers may play a crucial role as new molecular targets of heteromer-selective and bivalent ligands. The current review summarizes key recent developments in these topics.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Gaitonde SA,González-Maeso Jdoi
10.1016/j.coph.2016.10.006subject
Has Abstractpub_date
2017-02-01 00:00:00pages
23-31eissn
1471-4892issn
1471-4973pii
S1471-4892(16)30128-Xjournal_volume
32pub_type
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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