Abstract：
:Interferon-alpha-based therapies are the mainstay of hepatitis C treatment. However, these broad immunomodulatory agents, already limited by their side effects, expense and route of administration, are not efficacious in all cases. Therefore, research efforts have focused on identifying additional drugs and therapeutic modalities to benefit those individuals refractive to current therapy, and which might be more affordable, such as orally active small-molecule alternatives and preventive or therapeutic vaccines. It is likely that successful therapeutic intervention of hepatitis C will require a combination of approaches targeting different aspects of the viral life-cycle.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Tan SL,He Y,Huang Y,Gale M Jrdoi
10.1016/j.coph.2004.07.003keywords:
subject
Has Abstractpub_date
2004-10-01 00:00:00pages
465-70issue
5eissn
1471-4892issn
1471-4973pii
S1471-4892(04)00128-6journal_volume
4pub_type
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