Acute mercury exposition of virgin, pregnant, and lactating rats: Histopathological kidney and liver evaluations.

abstract：:Bisphenol A (BPA) has been widely reported to exert endocrine disrupting effects, including the induction of adipogenesis in cultured preadipocytes and intact animals. Because of the potential harm to human health, BPA is being substituted by structurally related bisphenols. Whether or not such BPA analogues are safe ...

journal_title：Environmental toxicology

authors： Ramskov Tetzlaff CN,Svingen T,Vinggaard AM,Rosenmai AK,Taxvig C

更新日期：2020-05-01 00:00:00

abstract：:Dibutyltin (DBT) is the degradation products of TBT, which is generally considered higher toxicity than TBT in the immune system. In order to learn more about the mechanisms of immune-toxic of DBT, we exposed zebrafish (Danio rerio) to 0, 1, 10 and 100 ng/L DBT for 8 weeks. At the end of the experiment, we determined ...

journal_title：Environmental toxicology

authors： Zhang CN,Zhang JL,Huang Y,Ren HT,Guan SH,Zeng QH

更新日期：2018-01-01 00:00:00

abstract：:Domestic exposure to biomass smoke represents the second cause of chronic obstructive lung disease. Previous studies have shown that exposure of guinea pigs to wood smoke is capable of generating oxidative stress in lung tissue, and this may involve a failure at a mitochondrial level, given its close relation with the...

journal_title：Environmental toxicology

authors： Granados-Castro LF,Rodríguez-Rangel DS,Montaño M,Ramos C,Pedraza-Chaverri J

更新日期：2015-04-01 00:00:00

abstract：:The prostate is an accessory reproductive gland that is sensitive to the action of exogenous compounds known as endocrine disrupters that alter normal hormonal function. Finasteride is a widely used chemical that acts to inhibit the conversion of testosterone in its most active form, dihydrotestosterone. It is known t...

journal_title：Environmental toxicology

authors： Maldarine JS,Sanches BDA,Santos VA,Amaro GM,Calmon MF,Rahal P,Góes RM,Vilamaior PSL,Taboga SR

更新日期：2020-01-01 00:00:00

abstract：:So far, little is known on the distribution of hepatotoxic microcystin (MC) in various organs of bivalves, and there is no study on MC accumulation in bivalves from Chinese waters. Distribution pattern and seasonal dynamics of MC-LR, -YR and -RR in various organs (hepatopancreas, intestine, visceral mass, gill, foot, ...

journal_title：Environmental toxicology

authors： Chen J,Xie P

更新日期：2005-12-01 00:00:00

abstract：:Increasing use of pesticides all over the world makes it necessary to reveal the toxic risk in populations of nontargeted organisms. Bendiocarb is one of the 12 insecticides recommended by the World Health Organization for use in malaria control in Africa, and is used against a variety of insects. The liver has an imp...

journal_title：Environmental toxicology

authors： Petrovova E,Purzyc H,Mazensky D,Luptakova L,Torma N,Sopoliga I,Sedmera D

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVES:We evaluated the role of oxidative stress in Sudan IV-induced DNA damage, using human liver-derived HepG2 cells. METHODS:The DNA damaging effects of Sudan IV in HepG2 cells were evaluated by alkaline single cell gel electrophoresis assay and micronucleus test (MNT). To clarify the underlying mechanisms, we ...

journal_title：Environmental toxicology

authors： Zhang Y,An Y,Jiang L,Geng C,Cao J,Jiang L,Zhong L

更新日期：2011-06-01 00:00:00

abstract：:Liver is one of the major target organs of arsenic toxicity and carcinogenesis. Nuclear factor (erythroid-2 related) factor 2 (Nrf2) is a redox-sensitive transcription factor, regulating critically cellular defense responses against the toxic metallic arsenic in many cell types and tissues. This study was conducted to...

journal_title：Environmental toxicology

authors： Li B,Li X,Zhu B,Zhang X,Wang Y,Xu Y,Wang H,Hou Y,Zheng Q,Sun G

更新日期：2013-07-01 00:00:00

abstract：:Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer that gives flexibility to various polyvinyl chloride products. It is a pollutant easily released into the environment and can cause many adverse effects to living organisms including hepatotoxicity. The thioredoxin system is a determining factor in the redox balance ...

journal_title：Environmental toxicology

authors： Amara I,Timoumi R,Annabi E,Di Rosa G,Scuto M,Najjar MF,Calabrese V,Abid-Essefi S

更新日期：2020-01-01 00:00:00

abstract：:Survival of juvenile freshwater mussels (Echyridella menziesii (Gray, 1843) formerly known as Hyridella menziesi) and crayfish (Paranephrops planifrons, White, 1842) decreased after four days exposure to microcystin-containing cell-free extracts (MCFE) of Microcystis sp. at concentrations typical of severe cyanobacter...

journal_title：Environmental toxicology

authors： Clearwater SJ,Wood SA,Phillips NR,Parkyn SM,Van Ginkel R,Thompson KJ

更新日期：2014-05-01 00:00:00

abstract：:Bergapten is a natural compound and has potent anticancer activities. In this study, we explored the cytotoxicity of bergapten on colorectal cancer (CRC) cell DLD-1 and LoVo and its underlying mechanisms. We observed that bergapten (30 and 50 μM) decreased the viability of the CRC cells and induced the G0/G1 and sub-G...

journal_title：Environmental toxicology

authors： Lin CP,Lin CS,Lin HH,Li KT,Kao SH,Tsao SM

更新日期：2019-03-01 00:00:00

abstract：:Polybrominated diphenyl ethers (PBDEs) are ubiquitous and prolific contaminant in both the abiotic and biotic environment because of the wide industrial applications of these chemicals. In the present study, the effects of 2,2',4,4'-tetrabrominateddiphenyl ether (BDE-47) and 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE...

journal_title：Environmental toxicology

authors： Meng S,Chen X,Gyimah E,Xu H,Chen J

更新日期：2020-11-01 00:00:00

abstract：:Lead ions (Pb(2+) ) are toxic industrial pollutants associated with chronic inflammatory diseases in humans and animals. Previously, we found that Pb(2+) ions induce COX-2 gene expression via the EGF receptor/nuclear factor-κB signal transduction pathway in epidermoid carcinoma cell line A431. In this study, to see wh...

journal_title：Environmental toxicology

authors： Tsai YT,Chang CM,Wang JY,Hou MF,Wang JM,Shiurba R,Chang WC,Chang WC

更新日期：2015-09-01 00:00:00

abstract：:The synergic allergic inflammatory effects of particulate matter (PM) 2.5 and human albumin were investigated in NC/Nga mice, which are hypersensitive to mite allergens. PM2.5 or PM2.5 plus human albumin with aluminum oxide was injected twice intraperitoneally for sensitization. After 7 days, PM2.5 or PM2.5 plus human...

journal_title：Environmental toxicology

authors： Nagaoka K,Ogino K,Ogino N,Ito T,Takemoto K,Ogino S,Seki Y,Hamada H,Fujikura Y

更新日期：2019-07-01 00:00:00

abstract：:Some species of the genera Anabaena can produce various kinds of cyanotoxins, which may pose risks to environment and human health. Anabaena has frequently been observed in eutrophic freshwater of China in recent years, but its toxicity has been reported only in a few studies. In the present study, the toxicity of an ...

journal_title：Environmental toxicology

authors： Pan X,Chang F,Liu Y,Li D,Xu A,Shen Y,Huang Z

更新日期：2009-02-01 00:00:00

abstract：:The aim of this study is to determine the chemical composition, and evaluate the genotoxic, and anti-growth potency of the methanol extracts of lichen species Hypogymnia physodes (L.) Nyl. (HPE). Anti-growth effect was tested in two different human breast cancer cell lines (MCF-7 and MDA-MB-231) by the MTT and ATP via...

journal_title：Environmental toxicology

authors： Ari F,Celikler S,Oran S,Balikci N,Ozturk S,Ozel MZ,Ozyurt D,Ulukaya E

更新日期：2014-05-01 00:00:00

abstract：:8-Hydroxy-2'-deoxyguanosine (8-OHdG) is the most common biomarker of oxidative DNA damage, it is formed by chemical carcinogens and can be measured in any species. Perfluorooctanoic acid (PFOA) and perfluorononanoic acid (PFNA) are suspected genotoxic carcinogens through induction of reactive oxygen species that are r...

journal_title：Environmental toxicology

authors： Yahia D,Haruka I,Kagashi Y,Tsuda S

更新日期：2016-02-01 00:00:00

abstract：:We hypothesized that chronic exposure to arsenic would deplete the reduced glutathione (GSH) and methionine in vivo, thereby impair the methylation capacity of inorganic arsenic (iAs) ingested. Our experiment was designed to explore the effects of exogenous GSH and methionine on arsenic methylation in mice exposed to ...

journal_title：Environmental toxicology

authors： Jin Y,Zhao F,Zhong Y,Yu X,Sun D,Liao Y,Lv X,Li G,Sun G

更新日期：2010-08-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are a class of organic pollutants that have been linked to pancreatic disease. However, their role in affecting the exocrine function of pancreas and the underlying mechanism remains elusive. In the present study, male C57 mice were treated with Aroclor 1254, a commercially available P...

journal_title：Environmental toxicology

authors： Lin M,Wu T,Sun L,Lin JJ,Zuo Z,Wang C

更新日期：2016-06-01 00:00:00

abstract：:Adrenomedullin (AdM) is synthesized and secreted by a number of cells and tissue. AdM is a potent vasodilator but it is also considered a neuromodulator, an angiogenic factor, and a hormone regulator. AdM possess antiapoptotic, antioxidant, and antimicrobial properties. Heavy metals such as cadmium and lead are found ...

journal_title：Environmental toxicology

authors： Yurekli M,Esrefoglu M,Ilker Doğru M,Doğru A,Gul M,Whidden M

更新日期：2009-06-01 00:00:00

abstract：:The 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidized nucleoside of DNA, not only is a widely used biomarker for the measurement of endogenous oxidative DNA damage, but might also be a risk factor for many diseases including cancer. Elevated level of urinary 8-OHdG has been detected in patients with various malignanci...

journal_title：Environmental toxicology

authors： Yang Y,Tian Y,Yan C,Jin X,Tang J,Shen X

更新日期：2009-10-01 00:00:00

abstract：:We performed an interspecies comparison for the human hepatoma cell line HepG2 and the eukaryotic single cell organism Tetrahymena pyriformis (T. pyriformis) for 17 xenobiotics with diverse structures and four metals. The cytotoxicity was assessed by four different cell viability assays (3-[4,5-dimethylthiazol-2-yl]-2...

journal_title：Environmental toxicology

authors： Rudzok S,Krejči S,Graebsch C,Herbarth O,Mueller A,Bauer M

更新日期：2011-04-01 00:00:00

abstract：:Airborne particulates, especially fine particles and bound chemical compounds, are a potential mediator of adverse health effects. In this study an analysis was done of the concentration and size distribution of air particulate matter, the content of bound polycyclic aromatic hydrocarbons (PAHs), and the biological ef...

journal_title：Environmental toxicology

authors： Massolo L,Müller A,Tueros M,Rehwagen M,Franck U,Ronco A,Herbarth O

更新日期：2002-01-01 00:00:00

abstract：:In the present study, the modulatory effect of phytol against benzo(a)pyrene [B(a)P] induced lung carcinogenesis was investigated in Swiss albino mice. During the experimental period, phytol treatment showed no adverse toxic effect and mortality to the experimental animals. Lung tumor was observed in B(a)P treated gro...

journal_title：Environmental toxicology

authors： Sakthivel R,Sheeja Malar D,Archunan G,Pandima Devi K

更新日期：2019-04-01 00:00:00

abstract：:The microbial assay for risk assessment (MARA) is an innovative system based on an array of 11 different microbial species freeze-dried in a 96-well micro-titer plate. Developed for testing the toxicity of chemicals, mixtures, and environmental samples, the assay employs species of a taxonomically diverse range. In ad...

journal_title：Environmental toxicology

authors： Wadhia K

更新日期：2008-10-01 00:00:00

abstract：:In recent years cyanobacteria blooms have become a severe problem in Taihu Lake, a large shallow eutrophic lake in China. Microcystins produced by certain genera of cyanobacteria can affect public health in this area because of their acute and chronic toxic effects. In this study, samples of cyanobacteria were collect...

journal_title：Environmental toxicology

authors： Wu JY,Xu QJ,Gao G,Shen JH

更新日期：2006-06-01 00:00:00

abstract：:Endotoxins exist anywhere including in water pools, dust, humidifier systems, and machining fluids. The major causal factor is endotoxins in many serious diseases, such as fever, sepsis, multi-organ failure, meningococcemia, and severe morbidities like neurologic disability, or hearing loss. Endotoxins are also called...

journal_title：Environmental toxicology

authors： Huang YC,Horng CT,Chen ST,Lee SS,Yang ML,Lee CY,Kuo WH,Yeh CH,Kuan YH

更新日期：2016-02-01 00:00:00

abstract：:The risk presented by β-blockers on aquatic organisms remains uncertain, particularly given the enantiospecific differences in toxicity of chiral β-blockers. In this study, the toxicity of two β-blockers, propranolol and metoprolol, was determined. The 96-h LC50 of propranolol in the zebrafish larvae was 2.48 mg/L, wh...

journal_title：Environmental toxicology

authors： Sun L,Xin L,Peng Z,Jin R,Jin Y,Qian H,Fu Z

更新日期：2014-12-01 00:00:00

abstract：:Indium, a rare earth metal characterized by high plasticity, corrosion resistance, and a low melting point, is widely used in the electronics industry, but has been reported to be an environmental pollutant and a health hazard. We designed a study to investigate the effects of subacute exposure of indium compounds on ...

journal_title：Environmental toxicology

authors： Lee KH,Chen HL,Leung CM,Chen HP,Hsu PC

更新日期：2016-01-01 00:00:00

abstract：:Benchmark dose (BMD) and the lower confidence limit on the benchmark dose (BMDL) of blood lead were estimated to explore the biologic exposure limits for renal dysfunction caused by lead. One hundred thirty-five workers from one storage battery plant were selected as lead exposure group while 143 mechanics as the cont...

journal_title：Environmental toxicology

authors： Lin T,Tai-Yi J

更新日期：2007-06-01 00:00:00