Abstract:
:To evaluate the treatment efficacies and toxicities of concurrent cetuximab-based bioradiotherapy (BRT) or cisplatin-based chemoradiotherapy (CRT) in locally advanced nasopharyngeal carcinoma. :Patients with previously untreated locally advanced nasopharyngeal carcinoma were matched into pairs, and enrolled into the study. All patients were given either BRT or CRT. Survival outcomes, toxicities, and prognostic factors were evaluated. :A total of 112 patients were enrolled. The 5-year overall survival was 79.3% and 79.5% in CRT and BRT arm, respectively (P = 0.797) and the 5-year DFS was 73.5% and 74.6%, respectively (P = 0.953). In toxicity analysis, CRT arm had more significant decrease in white blood cell, platelet, hemoglobin, and severe vomiting, while more severe skin reactions and mucositis were shown in BRT arm. :BRT was not less efficacious than traditional CRT. They lead to different aspects of toxicities. If patients cannot stand more severe toxicities caused by CRT, BRT could be an ideal alternative.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Wu X,Huang J,Liu L,Li H,Li P,Zhang J,Xie Ldoi
10.1097/MD.0000000000004926subject
Has Abstractpub_date
2016-09-01 00:00:00pages
e4926issue
39eissn
0025-7974issn
1536-5964pii
00005792-201609270-00040journal_volume
95pub_type
杂志文章相关文献
MEDICINE文献大全abstract:INTRODUCTION:Injection laryngoplasty is a common procedure for patients with vocal fold dysfunction, but the literature on its benefits has been mainly focused on those related to structural lesions or laryngeal nerve involvement. Stroke patients may be at increased risk of aspiration due to insufficient vocal fold mot...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019220
更新日期:2020-02-01 00:00:00
abstract::To evaluate the utility of blood pressure variability (BPV) calculated using previously published and newly introduced indices using the variables falls and age as comparators.While postural hypotension has long been considered a risk factor for falls, there is currently no documented evidence on the relationship betw...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003614
更新日期:2016-05-01 00:00:00
abstract::To compare the prevalence of hepatitis B virus (HBV) infection over a 10-year period in terms of population-level trends, we established hypothetical birth cohorts that represented each 10-year interval age group.We used data from the Korean National Health and Nutrition Examination Surveys conducted between 1998 to 2...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001469
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Asthma is the most common chronic lung disease in childhood, leading to a great burden to the healthcare system worldwide. Despite the medication treatment, physiotherapy is now applied for asthmatic children aiming to improve their lung function and life quality. However, the effectiveness of physiotherapy ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016195
更新日期:2019-06-01 00:00:00
abstract:RATIONALE:A characteristic metabolic finding of hepatic alveolar echinococcosis (HAE) on positron emission tomography/computed tomography (PET/CT) correlates with morphologic features on CT and magnetic resonance imaging (MRI). PATIENT CONCERNS:A young man from an endemic area was admitted to our hospital due to right...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014561
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION:Early diagnosis of acute kidney injury (AKI) remains a challenge. Recently, [TIMP-2]·[IGFBP7], which is a combination of urine tissue inhibitor of metalloproteinase 2 (TIMP-2) and insulin-like growth factor (IGF) binding protein 7 (IGFBP7), has been identified as a potential biomarker of AKI. We performed ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000007484
更新日期:2017-07-01 00:00:00
abstract::Thyroid complications resulting from excess iodide such as thyrotoxicosis, thyroiditis, sialadenitis, or hypothyroidism are much rarer after iodine supplementation with Lipiodol than with KI. They do not militate against its widespread use in endemic goiter populations, especially in pregnant women. However, patients ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-200101000-00003
更新日期:2001-01-01 00:00:00
abstract::A congenital peribronchial myofibroblastic tumor (CPMT) is a rare benign tumor arising from the lungs. Although CPMT is a benign tumor, it is characterized by rapid growth, and is easily misdiagnosed during the prenatal period when the symptoms are nonspecific. The authors present a rare case of CPMT in a premature in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001842
更新日期:2015-10-01 00:00:00
abstract::The objective of this study was to compare the differences between the measurements performed manually to those obtained using a digital model scanner of patients with orthodontic treatment.A cross-sectional study was performed in a sample of 30 study models from patients with permanent dentition who attended a univer...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010887
更新日期:2018-06-01 00:00:00
abstract::The purpose of this study was to assess whether breast cancer subtype (BCS) as determined by estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 can predict the axillary lymph node metastasis in breast cancer. Patients who received breast conserving surgery or mastectomy and axillary...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000002213
更新日期:2015-12-01 00:00:00
abstract:RATIONALE:Intraocular manifestation of hematopoietic tumors is rare and often difficult to distinguish from inflammation. We report a patient with acute lymphoblastic leukemia (ALL) who developed intraocular infiltration during the remission period. PATIENT CONCERNS:A 40-year-old man presented with hypopyon in his rig...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018872
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Chimeric antigen receptor T cells (CAR-T) targeting CD19 have shown great potential for treatment of B-cell malignancies. For those patients who can not achieve complete remission (CR) or suffer from relapse after CAR-T therapy, further therapeutic strategies still remain elusive. Whether existing CAR-T ce...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022510
更新日期:2020-10-23 00:00:00
abstract:RATIONALE:Congenital diaphragmatic hernia (CDH) associated congenital anomalies are present in about 25%. Congenital short esophagus (CSE) is a relatively rare condition. Both CDH and congenital intrathoracic stomach caused by CSE can be diagnosed in utero. However, CSE can be easily misdiagnosed in utero. PATIENT CON...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008996
更新日期:2017-12-01 00:00:00
abstract::[In the article "Uncompromised Treatment Efficacy in Elderly Patients With Hepatocellular Carcinoma: A Propensity Score Analysis", which appeared in Volume 93, Issue 28 of Medicine, one of the authors' affiliations, National Yang-Ming University School of Medicine, Taipei, Taiwan, was omitted. The article has since be...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000461199.07356.ca
更新日期:2015-01-01 00:00:00
abstract::The aim of this study was to investigate the influence of vertebral bone mineral density (BMD) on total diffusion volume of bone cement in percutaneous vertebroplasty (PVP). This study was a retrospective review of prospectively collected data of consecutive patients with A1.2 thoracolumbar compression fractures treat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014941
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:To assess the effect of dexmedetomidine added to ropivaccaine on the onset and duration of sensory block, as well as postoperative analgesia during caudal anesthesia in patients undergoing hemorrhoidectomy. METHODS:Fifty adult patients scheduled for hemorrhoidectomy were divided into 2 groups. The group R r...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000011731
更新日期:2018-08-01 00:00:00
abstract::The dopamine transporter (DAT) plays a crucial role in the pathogenesis of alcohol dependence (AD) and major depression (MD), and males have more risk factors for the development of AD. However, imaging studies on brain DAT availability in males with AD comorbid with MD (AD/MD) are limited, and the association of DAT ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004048
更新日期:2016-08-01 00:00:00
abstract::Acute myocardial infarction (AMI) is recognized as being a life-threatening event. Both microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH) have been recognized as poor prognostic factors in myocardial infarct (MI) since they adversely affect left ventricular remodeling. MVO refers to small vessels ch...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011617
更新日期:2018-07-01 00:00:00
abstract:RATIONALE:Castleman's disease (CD) is a rare lymphoproliferative disease. Compared to unicentric CD, multicentric Castleman disease (MCD) displays poorer prognosis and great variance to different therapies. Though chemotherapy, immunization therapy, and glucocorticoids have been used in the treatment of MCD, its optima...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017681
更新日期:2019-11-01 00:00:00
abstract:RATIONALE:Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor may be found as a solit...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000020869
更新日期:2020-06-26 00:00:00
abstract:BACKGROUND:We aimed to conduct a meta-analysis to evaluate the efficacy and safety between once daily (OD) and twice daily (BD) regime dosing of mesalazine for mild-to-moderate ulcerative colitis (UC). METHODS:PubMed, Embase, the Cochrane library, and Web of Science from 1990 to November 2018 were investigated. We sea...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000015113
更新日期:2019-04-01 00:00:00
abstract:RATIONALE:Arterial occlusion, a rare condition after total knee arthroplasty (TKA), may cause fatal outcomes if not treated on time. We report a case of arterial occlusion after undergoing navigated TKA with no tourniquet use, in a patient at high risk of postoperative arterial occlusion due to the patient's ipsilatera...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012719
更新日期:2018-10-01 00:00:00
abstract::Diarrhea-predominant irritable bowel syndrome (IBS-D) and functional diarrhea (FD) are highly prevalent, and the effectiveness of acupuncture for managing IBS-D and FD is still unknown.The aim of this study was to compare the effectiveness of electroacupuncture with loperamide.It was a prospective, randomized, paralle...
journal_title:Medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/MD.0000000000003884
更新日期:2016-06-01 00:00:00
abstract::Although step counters are increasingly being used in walking programmes to promote sedentary behavior changes in adults, their effectiveness remains unknown. The aim of this meta-analysis of randomized controlled trials (RCTs) was to assess the effectiveness of step counter use in reducing sedentary time among adults...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001412
更新日期:2015-09-01 00:00:00
abstract::The clinical symptoms of pylephlebitis caused by acute appendicitis are varied and atypical, which leads to delayed diagnosis and poor outcomes. Here, we report a case of intestinal necrosis caused by thrombophlebitis of the portomesenteric veins as a complication of acute appendicitis after appendectomy. The patient ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001033
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:To compare superb microvascular imaging with power Doppler imaging for evaluating joint lesion scores in rheumatoid arthritis based on high quality clinical cohort or case control studies. METHODS:We searched Medline (via PubMed), Web of Science, Cochrane Library, Embase, and Chinese Biomedical Literature D...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022185
更新日期:2020-09-11 00:00:00
abstract:RATIONALE:To report a patient with primary progressive freezing gait (PPFG) whose degeneration of corticofugal tract (CFT) from the supplementary motor area (SMA) was demonstrated using diffusion tensor tractography (DTT). PATIENT CONCERNS:A 66-year-old woman presented with a solitary symptom of a sudden transient bre...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006840
更新日期:2017-05-01 00:00:00
abstract::Cytokines are extensively involved in the process of hepatitis C virus (HCV) infection and take a crucial part in host immune regulation. We aimed to explore the potential correlation of cytokine single nucleotide polymorphisms (SNPs) with HCV susceptibility and response rate of interferon (IFN)-based antiviral therap...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022362
更新日期:2020-09-18 00:00:00
abstract::Hand-foot-and-mouth disease (HFMD) is a common childhood infection that may lead to serious complications and even death. Globally, epidemics of HFMD are increasing each year, especially in China. This study aimed to identify risk factors for death in children with critical and severe HFMD in Chongqing, China.We perfo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008934
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Generally, rheumatic heart disease is, today, sporadic in developed countries, even though it continues to be a major health hazard in the developing ones. It is also a very rare cause of sudden unexpected death. We report a case of a 15-year-old boy who suddenly died at home. Since 3 days he had presented f...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004586
更新日期:2016-08-01 00:00:00