Lymphodepletion chemotherapy revitalizes chimeric antigen receptor T cells contributing to regression of relapsed B-cell lymphoma: A case report.

abstract：:Actinic keratoses (AKs) are precancerous epidermal lesions that develop on sensitive, frequently sun-exposed skin surfaces. There are very little data regarding AK prevalance. The aim of this study was to investigate the prevalence of AK and related conditions among patients in a dermatology outpatient clinic.Patients...

journal_title：Medicine

authors： Yaldiz M

更新日期：2019-07-01 00:00:00

abstract：RATIONALE:Philadelphia chromosome-positive mixed phenotype acute leukemia (Ph+ MPAL) is a rare type of leukemia with poor prognosis. Tyrosine kinase inhibitors (TKIs) in combination with chemotherapy have significantly improved its remission rate. However, relapse remains the major obstacle to achieve long survival. Le...

journal_title：Medicine

authors： Lai B,Mu Q,Zhu H,Wang Y,Zhang Y,Xu K,Sheng L,Ouyang G

更新日期：2018-04-01 00:00:00

abstract：:This study is to investigate the effect of metabotropic glutamate receptor 7 (mGluR7) on the proliferation of human embryonic neural stem cells (NSCs) and its molecular mechanism.Human embryonic NSCs were isolated. The pCMV2-GV146-GFP-mGluR7 plasmid was transfected to over-express mGluR7 while mGluR7 siRNA was transfe...

journal_title：Medicine

authors： Zhang J,Zhao J,Chen Y,Shi H,Huang X,Wang Y,Wang Y,Wei Y,Xue W,Han J

更新日期：2019-03-01 00:00:00

abstract：RATIONALE:Sarcomatous or anaplastic carcinoma mural nodules presenting in ovarian mucinous cystic tumors are very rare. Here, we reported the ultrasonic and pathological features of 2 such cases. PATIENT CONCERNS:A 60-year-old woman presented with a complaint of lower abdominal pain. Physical examination revealed a ha...

journal_title：Medicine

authors： Zhang Y,Yuan Z,Sun K,Li P

更新日期：2017-11-01 00:00:00

abstract：:Signet ring cell carcinoma (SRC) is a poorly differentiated cancer of the stomach. Generally, poorly differentiated cancer is believed to show poor prognosis and aggressive behavior. Recently, however, there is debate on the aggressiveness of SRC in early gastric cancer (EGC). We therefore studied postoperation biopsi...

journal_title：Medicine

authors： Kang SH,Kim JS,Moon HS,Lee ES,Kim SH,Sung JK,Lee BS,Jeong HY

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The use of hysteroscopy for the diagnosis and treatment of uterine and endometrial abnormalities is often associated with postoperative pain. This randomized controlled trial aimed to assess the efficacy of preoperative intravenous (IV) lidocaine in reducing pain after hysteroscopy. METHODS:In total, 138 pa...

journal_title：Medicine

authors： Lee J,Lee S,Lee H,Kim HC,Park C,Kim JY

更新日期：2020-10-16 00:00:00

abstract：:To evaluate the predictive and prognostic significance of the prognostic nutritional index (PNI) in a large cohort of gastric cancer patients who underwent gastrectomy.Assessing a patient's immune and nutritional status, PNI has been reported as a predictive marker for surgical outcomes in various types of cancer.We r...

journal_title：Medicine

authors： Lee JY,Kim HI,Kim YN,Hong JH,Alshomimi S,An JY,Cheong JH,Hyung WJ,Noh SH,Kim CB

更新日期：2016-05-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a common and genetically heterozygous inflammatory rheumatic disease characterized by new bone formation, ankylosis and inflammation of hip, sacroiliac joints and spine. Until now, there is no method for early diagnosis of AS and the effective treatment available for AS patients remain l...

journal_title：Medicine

authors： Li Z,Wong SH,Shen J,Chan MTV,Wu WKK

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss that is characterized by depression, anxiety and social isolation. In recent years, Plum-blossom needle plus Chinese herbal medicine has gradually shown its clinical advantages and been more and more widely used in China. Whereas, ...

journal_title：Medicine

authors： Tang G,Xiong J,Fan Q,Guo H,Zhou X,Zhu S,Zhong Z,Chen J,Lu L

更新日期：2020-10-09 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is the most common and frequently dangerous neonatal gastrointestinal disease. Studies have shown broad-spectrum antibiotics plus anaerobic antimicrobial therapy did not prevent the deterioration of NEC among very low birth preterm infants. However, few studies about this therapy which ...

journal_title：Medicine

authors： Luo LJ,Li X,Yang KD,Lu JY,Li LQ

更新日期：2015-10-01 00:00:00

abstract：:Meibomian gland dysfunction (MGD) is believed to be the leading cause of dry eye (DE) disease worldwide. The connection between aging and MGD has long been recognized. However, few studies have addressed the relationship between MGD and hormone replacement therapy (HRT) in perimenopausal women, and not have examined t...

journal_title：Medicine

authors： Jin X,Lin Z,Liu Y,Lin L,Zhu B

更新日期：2016-08-01 00:00:00

abstract：RATIONALE:Report a case of bilateral multiple retinal hamartomas (RAHs) in a patient with tuberous sclerosis complex (TSC) and introduced a new method (subthreshold micropulse laser photocoagulation) for the treatment of RAHs. PATIENT CONCERNS:A 20-year-old man with TSC complained of decreased vision and metamorphosia...

journal_title：Medicine

authors： Yan S,Chen Y,Chen R,Tian B,Li Z

更新日期：2018-12-01 00:00:00

abstract：:We retrospectively compared accelerated hypofractionation (AHF) with conventional fractionation (CF) in the radiation therapy (RT) for early-stage breast cancer patients.Three hundred seventy-nine early-stage (pT1-2 and pN0-1a) breast cancer patients who received RT with AHF after breast-conserving surgery (BCS) were ...

journal_title：Medicine

authors： Lee SW,Kim YJ,Shin KH,Kim K,Chie EK,Han W,Im SA,Jung SY,Lee KS,Lee ES

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The corona virus disease 2019 (COVID-19) has caused a global pandemic, there are no specific drugs and vaccines for epidemic control at present. More and more clinical practice shows that traditional Chinese medicine has played an important role in the outbreak. Among them, Qingfei Paidu decoction (QPD) comb...

journal_title：Medicine

authors： Gao K,Song YP,Chen H,Zhao LT,Ma L

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:Talaromyces marneffei (T marneffei), known as a significant pathogen in patients with AIDS in Southeast Asia, is a dimorphic fungus, which can cause deadly systematic infection in immunocompromised hosts. What is more, the dimorphic phase transition has been reported as a conspicuous process linked with viru...

journal_title：Medicine

authors： Cen J,Chen J,Qiu Y,Zeng W,Zhang J

更新日期：2020-11-25 00:00:00

abstract：RATIONALE:Unicompartmental knee arthroplasty (UKA) is an effective method to treat single compartment disease of the knee joint. Report about the complications of UKA, especially tibial plateau fractures, is rare. Given its rarity, its pathogenesis is not well described, and a standard of treatment is still not establi...

journal_title：Medicine

authors： Lu C,Ye G,Liu W,Wu H,Wu G,Chen J

更新日期：2019-10-01 00:00:00

abstract：:Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. FM frequently results in the compression of vital mediastinal structures and has been associated with substantial morbidity and mortality. Its pathogenesis remains unknown. However, in ...

journal_title：Medicine

authors： Peikert T,Colby TV,Midthun DE,Pairolero PC,Edell ES,Schroeder DR,Specks U

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Published association studies have investigated the correlation between interleukin-8 (IL-8) gene polymorphism -251T>A and susceptibility to Alzheimer's disease (AD); however, the results are conflicting. Thus, we conducted the meta-analysis to reassess the effect of IL-8 gene -251T>A variant on the risk of ...

journal_title：Medicine

authors： Qin B,Li L,Wang S,Wu J,Huang Y,Zhou P,Bai J,Zheng Y

更新日期：2016-09-01 00:00:00

abstract：:Extraintestinal manifestations (EIMs) cause increased morbidity and decreased quality of life in Crohn disease (CD). Ankylosing spondylitis (AS) belongs to EIMs. Very little is known on the clinical features of CD concomitant with AS. This study is to investigate the clinical features of CD patients with AS.We retrosp...

journal_title：Medicine

authors： Liu S,Ding J,Wang M,Zhou W,Feng M,Guan W

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The prognostic significance of phosphatase and tensin homolog (PTEN) in patients with breast cancer (BC) remains controversial. The aims of our meta-analysis are to evaluate its association with clinicopathological characteristics and prognostic value in patients with breast cancer. METHODS:PubMed, EMBASE, ...

journal_title：Medicine

authors： Xu F,Zhang C,Cui J,Liu J,Li J,Jiang H

更新日期：2017-09-01 00:00:00

abstract：:[This corrects the article DOI: 10.1097/MD.0000000000002306.]. ...

journal_title：Medicine

authors：

更新日期：2016-03-03 00:00:00

abstract：RATIONALE:ST-segment elevation localizes an ischemic lesion to the coronary artery supplying the area of the myocardium reflected by the electrocardiographic leads. Dynamic ST-segment elevation can be due to severe transmural ischemia secondary to a thrombus, vasospasm, or a tightly fixed coronary artery lesion or a co...

journal_title：Medicine

authors： Hung MJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) and Crohn disease (CD) are the 2 main types of inflammatory bowel diseases (IBDs). Several studies have been conducted to investigate the association of Glutathione S-Transferase M1 (GSTM1) null genotype with UC and CD, but the results are inconsistent. Here, we performed a meta-analy...

journal_title：Medicine

authors： Zhou YJ,Zhao BL,Qian Z,Xu Y,Ding YQ

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to observe the counter-effect of carbon monoxide-releasing molecule-2 (CORM-2) on lipopolysaccharide (LPS)-suppressed thrombomodulin (TM) and endothelial protein C receptor (EPCR) expressions from human umbilical vein endothelial cell (HUVEC), and to reveal its mechanisms. METHODS:H...

journal_title：Medicine

authors： Meng X,Fei D,Liu M,Yang S,Song N,Jiang L,Kang K,Nan C,Luo Y,Pan S,Zhao M

更新日期：2017-05-01 00:00:00

abstract：:To analyze the impact of perigastric lipolymphatic tissue grouping by the surgeon on the number of pathologic sampled lymph nodes and to explore the appropriate lymph node delivery process.The authors collected the medical records of gastric cancer patients who were hospitalized in Wuhan Union Hospital during the peri...

journal_title：Medicine

authors： Cao Y,Xiong L,Deng S,Shen L,Li J,Wu K,Wang J,Tao K,Wang G,Cai K

更新日期：2018-07-01 00:00:00

abstract：:Indentation hardness test is a good in vitro method of bone quality assessment. The purpose of this study is to explore the distribution characteristics of bone tissue microhardness in tibial diaphysis and provide theoretical support for the test site selection of the reference point indentation technique.Three fresh ...

journal_title：Medicine

authors： Wang J,Yin B,Liu G,Li S,Zhang X,Hu Z,Wu W,Zhang Y

更新日期：2019-07-01 00:00:00

abstract：RATIONALE:Pegaspargase has been used in the treatment of acute lymphoblastic leukemia with promising results. However, it has also been associated with several potentially serious complications, including thrombosis. Pegaspargase-induced cerebral venous thrombosis and bone marrow necrosis are very rare. PATIENT CONCER...

journal_title：Medicine

authors： Sui J,Zhang Y,Yang L,Wang H,Xu J,Wei R,Hao Y,Wang X,Peng J,Ma J

更新日期：2017-11-01 00:00:00

abstract：:Teenage mothers are at high risk for maternal and neonatal complications. This study aimed to evaluate the socioeconomic circumstances of teenage pregnancy, and determine whether these increased risks remained after adjustment for socioeconomic circumstances in Korea. Using the National Health Insurance Corporation da...

journal_title：Medicine

authors： Lee SH,Lee SM,Lim NG,Kim HJ,Bae SH,Ock M,Kim UN,Lee JY,Jo MW

更新日期：2016-08-01 00:00:00

abstract：RATIONALE:Gouty panniculitis, characterised by the deposition of monosodium urate crystals in subcutaneous tissue, is a rare clinical manifestation of gout. PATIENT CONCERNS:The case of a 67-year-old man is reported, who presented an erythematous nodule on the upper part of the right buttock suspicious for an abscess....

journal_title：Medicine

authors： Martin D,Joliat GR,Fournier P,Brunel C,Demartines N,Gié O

更新日期：2017-04-01 00:00:00

abstract：:This research aims to explore the accurate incidence, severity and outcomes of dysphagia and dysphonia after Hangman fractures.A total of 93 patients were included in this study and clinical data were reviewed. The Bazaz grading system (0-None; 1-Mild; 2-Moderate; 3-Severe) was used for dysphagia evaluation and the Vo...

journal_title：Medicine

authors： Yang Y,Dai L,Ma L,Gao X,Liu H

更新日期：2018-12-01 00:00:00