Abstract:
RATIONALE:Report a case of bilateral multiple retinal hamartomas (RAHs) in a patient with tuberous sclerosis complex (TSC) and introduced a new method (subthreshold micropulse laser photocoagulation) for the treatment of RAHs. PATIENT CONCERNS:A 20-year-old man with TSC complained of decreased vision and metamorphosia in both eyes for 2 months. At presentation, visual acuity (VA) was 20/32 in the right eye and 20/40 in the left eye. Fundus photographs, optical coherence tomography, fundus fluorescein angiography (FFA), and indocyanine green angiography indicated multiple RAHs in both eyes. DIAGNOSES:Bilateral retinal astrocytic hamartomas. INTERVENTIONS:In the right eye, 577 nm photocoagulation was adopted to treat the RAHs with obvious fluorescein leakage in FFA. The paramacular RAHs were treated by subthreshold micropulse mode to minimize the damage to macula. Photocoagulation therapy was administrated in the left eye after 1 dose of intravitreal ranibizumab treatment. OUTCOMES:After photocoagulation therapy (including subthreshold micropulse laser photocoagulation for the paramacular RAHs in both eyes), the VA improved to 20/25 OD and 20/32 OS with no recurrence of exudation. LESSONS:About 577 nm photocoagulation for the peripheral RAHs in combination with subthreshold micropulse laser photocoagulation for RAHs in the macular zone is a good option for multiple RAHs in patients with TSC.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Yan S,Chen Y,Chen R,Tian B,Li Zdoi
10.1097/MD.0000000000013265subject
Has Abstractpub_date
2018-12-01 00:00:00pages
e13265issue
50eissn
0025-7974issn
1536-5964pii
00005792-201812140-00009journal_volume
97pub_type
杂志文章相关文献
MEDICINE文献大全abstract::Extraintestinal manifestations (EIMs) cause increased morbidity and decreased quality of life in Crohn disease (CD). Ankylosing spondylitis (AS) belongs to EIMs. Very little is known on the clinical features of CD concomitant with AS. This study is to investigate the clinical features of CD patients with AS.We retrosp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004267
更新日期:2016-07-01 00:00:00
abstract::Different patterns of milk and breast cancer rates across countries suggest that several components of milk could affect breast cancer risk. However, the components of diet are complex including milk that could potentially influence risk. Some milk products such as whole milk and cheese have a high fat content which m...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000014900
更新日期:2019-03-01 00:00:00
abstract:RATIONALE:The optimal therapeutic regimen for chemotherapy-refractory and node-positive small-cell lung cancer (SCLC) is criticizable for the lack of evidence. PATIENT CONCERNS:A patient with locally advanced SCLC was insensitive to the first-line chemotherapy of etoposide, irinotecan, and cisplatin. DIAGNOSES:The pa...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000008922
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Femoral nerve block (FNB) is considered the preferred analgesia after anterior cruciate ligament reconstruction (ACLR), but leads to weakness in the quadriceps muscles. Adductor canal block (ACB) is a new sensory block technique that effectively relieves postoperative pain while preserving quadriceps strengt...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020776
更新日期:2020-07-10 00:00:00
abstract::This study was aimed to evaluate whether silver-containing dressings were superior to other types of dressings in the treatment of venous leg ulcers (VLU) and their specific advantages.Eight databases (Cochrane Library, PubMed, Web of Science, Ovid-Medline, Wanfang, VIP, China Biology Medicine, and China National Know...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022164
更新日期:2020-09-11 00:00:00
abstract::Many studies suggest that catalase C-262T gene polymorphism is associated with cancer risk, but with inconsistent results. This study aimed to summarize the overall association between catalase C-262T polymorphism and cancer risk. Literature search was performed in PubMed, Embase, and other databases, studies regardin...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000000679
更新日期:2015-04-01 00:00:00
abstract::Strength training has, in recent years, been shown to be beneficial for people with Parkinson disease and multiple sclerosis. Consensus regarding its utility for these disorders nevertheless remains contentious among healthcare professionals. Greater clarity is required, especially in regards to the type and magnitude...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000000411
更新日期:2015-01-01 00:00:00
abstract:RATIONALE:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. It appears as patches, plaques, and tumors depending on the stage of the disease, which presents a chronic progressive course. Compared to CD4/CD8 MF, CD4/CD8 dual-positive MF is an uncommon immune phenotype. PATIENT CONCERNS:A 36-year-old ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000022786
更新日期:2020-10-16 00:00:00
abstract::Recent studies have revealed a link between estradiol (E2) and glucose homeostasis. We aimed to assess the association between cord blood hormone levels and the risk of gestational diabetes mellitus (GDM).A total of 204 pregnant women with GDM and 204 pregnant women without GDM (control) were included in the study. Ma...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006962
更新日期:2017-05-01 00:00:00
abstract::The aim of the study was to assess the independent contribution of hyperuricemia to coronary artery disease (CAD) confirmed by coronary angiography (CAG), and to explore associations between serum uric acid (SUA) level and CAD.We performed a retrospective cohort study of 5069 patients who underwent CAG. Patients were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012926
更新日期:2018-11-01 00:00:00
abstract::The aim of this observational study was to test whether ABO blood type was a prognostic factor for pancreatic ductal adenocarcinoma (PDAC) patients and whether other risk factors could influence pancreatic cancer patients' survival. This study included 610 patients who were diagnosed as pancreatic cancer and had under...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019413
更新日期:2020-04-01 00:00:00
abstract:RATIONALE:More mature or older women are more likely to undergo in vitro fertilization and embryo implant. These women have a greater chance of receiving ergonovine therapy because of a suspected abortion. We present this case report to call attention to a latent lethal adverse effect in everyday obstetric practice usi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008559
更新日期:2017-11-01 00:00:00
abstract::Primary Amyloid Light-chain (AL) amyloidosis is a rare form of plasma cell dyscrasia characterized by tissue deposition of monoclonal immunoglobulin light chain. Kidney involvement is the most frequent manifestation, and patients usually present with glomerular disease.We report an exceptional case of bilateral kidney...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000777
更新日期:2015-05-01 00:00:00
abstract::Transient receptor potential vanilloid-1 (TRPV1) receptor and proteinase-activated receptor 2 (PAR2) have been implicated in the mechanism of acid-induced inflammation in gastroesophageal reflux disease (GERD). We aimed to evaluate TRPV1 and PAR2 mRNA expression levels in the GERD patients and their relationship with ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004387
更新日期:2016-08-01 00:00:00
abstract:RATIONALE:The emphysematous prostatic abscess is a rare but potentially life-threatening clinical condition. The early diagnosis is difficult due to nonspecific symptoms. PATIENT CONCERNS:A 72-year-old man with poorly controlled diabetes mellitus was admitted to hospital because of dysuria and acute urine retention. H...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000019391
更新日期:2020-02-01 00:00:00
abstract:RATIONALE:The fundamental pathogenesis of Behçet disease (BD) is still unclear and controversial. Many cases of oral aphthous ulcers and genital ulcers related to BD are reported; nevertheless, idiopathic giant esophageal ulcers related to BD are rare. A rare case for esophageal ulcers related to BD is presented. PATI...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008469
更新日期:2017-11-01 00:00:00
abstract::Graft insertion into the anterior chamber is one of the most important procedures for successful Descemet membrane endothelial keratoplasty (DMEK). Especially in eyes with fragile zonular fibers and a shallow anterior chamber, smooth graft insertion tends to become more difficult. Ophthalmic viscoelastic devices (OVDs...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011245
更新日期:2018-06-01 00:00:00
abstract:RATIONALE:Due to unprecedented global aging, the number of elderly and super-elderly patients with cancer is increasing. However, restricted by comorbidities or fragility, many elderly patients are considered ineligible to receive invasive therapies. A centenarian with primary liver cancer (PLC) was treated by external...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022473
更新日期:2020-11-20 00:00:00
abstract::The purpose of this study was to investigate the association of herpes zoster infection with peptic ulcer disease in a Korean population.The Korean National Health Insurance Service selects samples directly from the entire Korean population database, and 1,125,691 participants with 114,369,638 medical claim codes were...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019318
更新日期:2020-02-01 00:00:00
abstract:RATIONALE:This study aims to evaluate the diagnostic value of beta-endorphin (β-EP) and brain natriuretic peptid (BNP) plasma concentrations for the early diagnosis of acute left heart failure and atrial fibrillation. PATIENT CONCERNS:A total of 45 patients were included. These patients comprised 23 male and 22 female...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007526
更新日期:2017-08-01 00:00:00
abstract::The objective of this study was to carry out a large population-based study to understand the factors associated with hypoglycemia-related hospitalizations among older Korean adults with diabetes mellitus.This study analyzed data from a subset of the 2013 Health Insurance and Review and Assessment service-Adult Patien...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000005016
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Undiagnosed pleural effusions (UPEs) are a common problem of respiratory medicine, leading to an increased diagnostic burden globally. However, the most efficient and cost-effective approaches to UPEs remain controversial. This study aimed to assess the diagnostic value of ultrasound-guided nee...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000021076
更新日期:2020-07-02 00:00:00
abstract:RATIONALE:Hepatic alveolar echinococcosis (HAE) presents a high pathogenicity and case fatality rate. The main treatment for HAE is surgical resection. Giant lesions in the liver and invasion of the pathogen into the retrohepatic inferior vena cava are usually associated with a poor prognosis when radical resection can...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021336
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:Contrast-induced nephropathy (CIN) is acute renal failure observed after administration of iodinated contrast media during angiographic or other medical procedures. In recent years, many studies have focused on biomarkers that recognize CIN and/or predict its development in advance. One of the many biomarker...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016801
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Lesions of herpes labialis are caused by the herpes simplex virus type 1 and cause pain and aesthetic compromise. It is characterized by the formation of small vesicles that coalesce and rupture forming extremely painful ulcers, that evolve to crusts, dry desquamations until their complete remission. Current...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000019500
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. However, its etiology and fundamental pathophysiology for the disease process are poorly understood. In this study, we thus used bioinformatics to identify candidate genes potentially causative of severe NAFLD. ME...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007743
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Glypican-3 (GPC3) has been widely recognized in the progression of liver tumors for several years. The relationship between overexpression of GPC3 and the poorer prognosis of patients with hepatocellular carcinoma (HCC) was performed by 2 meta-analyses. However, there were also some latest literatures that i...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000011130
更新日期:2018-06-01 00:00:00
abstract::Central nervous system (CNS) nocardiosis is a rare disease entity caused by the filamentous bacteria Nocardia species. We present a case series of 5 patients from our hospital and a review of the cases of CNS nocardiosis reported in the literature from January 2000 to December 2011. Our results indicate that CNS nocar...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000000012
更新日期:2014-01-01 00:00:00
abstract::Ovarian masses are one of the most frequently identified entities in gynecological practice. Early differential diagnosis is a key factor in the medical management of each patient. Transvaginal ultrasound along with additional preoperative testing, such as serum cancer antigen 125 (CA-125) levels and the Risk of Ovari...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011762
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Although several studies have investigated the role of psychological factors in atrial fibrillation (AF), the results are still under debate. Therefore, we performed a meta-analysis to examine the relationship between psychological factors and the risk of incident AF. METHODS:We systematically searched the ...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000019615
更新日期:2020-04-01 00:00:00