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Optimized holographic femtosecond laser patterning method towards rapid integration of high-quality functional devices in microchannels.

Abstract：

:Rapid integration of high-quality functional devices in microchannels is in highly demand for miniature lab-on-a-chip applications. This paper demonstrates the embellishment of existing microfluidic devices with integrated micropatterns via femtosecond laser MRAF-based holographic patterning (MHP) microfabrication, which proves two-photon polymerization (TPP) based on spatial light modulator (SLM) to be a rapid and powerful technology for chip functionalization. Optimized mixed region amplitude freedom (MRAF) algorithm has been used to generate high-quality shaped focus field. Base on the optimized parameters, a single-exposure approach is developed to fabricate 200 × 200 μm microstructure arrays in less than 240 ms. Moreover, microtraps, QR code and letters are integrated into a microdevice by the advanced method for particles capture and device identification. These results indicate that such a holographic laser embellishment of microfluidic devices is simple, flexible and easy to access, which has great potential in lab-on-a-chip applications of biological culture, chemical analyses and optofluidic devices.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Zhang C,Hu Y,Du W,Wu P,Rao S,Cai Z,Lao Z,Xu B,Ni J,Li J,Zhao G,Wu D,Chu J,Sugioka K

doi

10.1038/srep33281

subject

Has Abstract

pub_date

2016-09-13 00:00:00

pages

33281

issn

2045-2322

pii

srep33281

journal_volume

6

pub_type

杂志文章

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